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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ELTLRTIADEDDYESYMASAYSVFLRDPQKDEIEVNRKFTELDRMIGFHDGKKWVATTGAFSRHVVLPGGAVVPVAAVTA
VTVSPTHRRRGLLTTMMRHQLADIRSRGESLAMLFASYGRFGYGVATESAELSGQVRELAFRPTVDLGDGTLEEVSAETF
LASAPAIYDAVIPGLPGQMSRTPEWWASWTLDSEELQKESGKVRFVLHYESDGTASGFAIYRPKPGWGGPNAELHVQEVL
GTNPRSYARTWRYLLDMDLVRKIKYHGASVQEELRYLVANHPSLECVVSDAIQVRLVDIPRALAQRRYAADVDVVLEVTD
DFLPENSGRYRLRGGLDHASCEITTDDADIALTVRDLGSVYMGGVSLQVLASAGLVTELRAGAVQRAATAFGWPVAPSAP
DDF

The query sequence (length=403) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6rft:A 406 407 0.9950 0.9877 0.9853 0.0 6rft:B, 6rft:C, 6rft:D, 6rft:E, 6rft:F, 6rfx:D, 6rfx:A, 6rfx:B, 6rfx:C, 6rfx:E
2 6yca:A 390 374 0.3027 0.3128 0.3262 7.30e-41 6yca:F, 6yca:B, 6yca:C, 6yca:D, 6yca:E
3 4qb9:A 402 396 0.3002 0.3010 0.3056 8.16e-38 4qb9:B, 4qb9:C, 4qb9:D, 4qb9:E, 4qb9:F, 3sxn:A, 3sxn:B, 3sxn:C, 3sxn:D, 3sxn:E, 3sxn:F
4 6b3t:A 396 394 0.2680 0.2727 0.2741 1.32e-23 6b0u:A, 6b0u:B, 6b0u:C, 8d1r:A, 8d23:A, 8d25:A, 5ebv:A, 5ec4:A, 8f4a:A, 8f4t:A, 8f4u:A, 8f4w:A, 8f4z:A, 8f51:A, 8f55:A, 8f57:A, 8f58:A, 5iv0:A, 4jd6:A, 4jd6:B, 4jd6:C, 4jd6:D, 4jd6:E, 4jd6:F, 6p3t:A, 6p3u:A, 6p3v:A, 3r1k:A, 3ryo:A, 3ryo:B, 3ryo:C, 3ryo:D, 3ryo:E, 3ryo:F, 3ryo:G, 3ryo:H, 3ryo:I, 3ryo:J, 3ryo:K, 3ryo:L, 5tvj:A, 6vur:A, 6vus:A, 6vut:A, 6vuu:A, 6vuw:A, 6vux:A, 6vuy:A, 6vuz:A, 6vv0:A, 6vv1:A, 6vv2:A, 6vv3:A, 6x10:A, 6x6g:AAA, 6x6i:AAA, 6x6y:AAA, 6x7a:AAA
5 4my0:C 392 408 0.2481 0.2551 0.2451 5.07e-09 4my0:A, 4my0:E, 4my0:B, 4my0:D, 4my0:F
6 2ozg:A 388 319 0.1762 0.1830 0.2226 1.32e-06
7 2q0y:A 153 60 0.0447 0.1176 0.3000 0.12
8 4j3h:A 42 28 0.0298 0.2857 0.4286 0.63 4j3h:B
9 4evy:A 147 55 0.0372 0.1020 0.2727 4.2 4evy:B
10 8ia0:CZ 576 104 0.0670 0.0469 0.2596 4.3
11 5t7e:D 175 32 0.0323 0.0743 0.4062 5.0 5t7d:A, 5t7d:B, 5t7d:C, 5t7d:D, 5t7e:A, 5t7e:B, 5t7e:C
12 7k36:I 599 53 0.0422 0.0284 0.3208 5.5
13 2zg3:A 210 39 0.0323 0.0619 0.3333 6.5 2zg1:A
14 5nnp:B 179 35 0.0347 0.0782 0.4000 7.8 5nnp:F
15 8fia:A 1772 26 0.0347 0.0079 0.5385 8.8
16 1xx4:A 254 69 0.0521 0.0827 0.3043 9.2
17 1gqy:B 469 62 0.0521 0.0448 0.3387 9.4 1gqy:A, 1p31:A, 1p31:B, 1p3d:A, 1p3d:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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