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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAP
SCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQN
EEITALKIKYNPFAKAFLDAK

The query sequence (length=181) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6f59:B 185 181 0.9945 0.9730 0.9945 2.52e-136 8a7n:A, 8cdn:A, 6f58:A, 6f58:B, 6f59:A, 8fmu:A, 8fmu:B, 5qrf:A, 5qrg:A, 5qrh:A, 5qri:A, 5qrj:A, 5qrk:A, 5qrl:A, 5qrm:A, 5qrn:A, 5qro:A, 5qrq:A, 5qrr:A, 5qrs:A, 5qrt:A, 5qru:A, 5qrv:A, 5qrw:A, 5qrx:A, 5qry:A, 5qrz:A, 5qs0:A, 5qs1:A, 5qs3:A, 5qs4:A, 5qs5:A, 5qs6:A, 5qs7:A, 5qs9:A, 5qsa:A, 5qsb:A, 5qsc:A, 5qsd:A, 5qse:A, 5qsf:A, 5qsg:A, 5qsh:A, 5qsj:A, 5qsk:A, 5qsl:A, 5qt0:A, 1xbr:A, 1xbr:B, 7zk2:A, 6zu8:A
2 5flv:M 229 177 0.5414 0.4279 0.5537 2.10e-68 5flv:A, 5flv:E, 5flv:I, 4s0h:A, 4s0h:B, 4s0h:E, 4s0h:F, 6wc2:N, 6wc2:M, 6wc2:O, 6wc5:I, 6wc5:N, 2x6u:A, 2x6v:A, 2x6v:B
3 1h6f:B 186 182 0.5193 0.5054 0.5165 4.29e-63 1h6f:A
4 5t1j:B 192 191 0.5359 0.5052 0.5079 2.45e-61 5t1j:A
5 4a04:B 190 188 0.5083 0.4842 0.4894 2.46e-57 4a04:A
6 6jta:A 1298 39 0.0608 0.0085 0.2821 2.2 7dw7:A, 6jt7:A, 6jt8:A, 6jt9:A, 4l78:A, 4lgy:A, 6lyk:A, 6lyl:A, 6lym:A, 6lyo:A, 4mgh:A, 4r7g:A, 1t3t:A, 3ugj:A, 3ujn:A, 3umm:A
7 7ug9:A 206 71 0.0939 0.0825 0.2394 5.3
8 2vxo:B 658 44 0.0829 0.0228 0.3409 6.1 2vxo:A
9 3jsz:A 520 90 0.1436 0.0500 0.2889 6.9 3jt1:A, 2wzg:A
10 3rsj:A 406 81 0.1271 0.0567 0.2840 8.0 3rsj:B, 3rsj:C, 3rsj:D
11 7tau:A 951 44 0.0608 0.0116 0.2500 8.5 7tau:C, 7tau:D, 7tau:E, 7tau:F, 7tau:H, 7tau:I, 7tau:G, 7tau:K, 7tau:L, 7tau:J, 5tx1:A, 5tx1:C, 5tx1:D, 5tx1:E, 5tx1:F, 5tx1:H, 5tx1:I, 5tx1:G, 5tx1:J, 5tx1:L
12 2wzf:A 515 90 0.1436 0.0505 0.2889 8.7
13 1wyw:A 216 29 0.0608 0.0509 0.3793 9.0 5cys:A, 5ff8:A, 4fnc:A, 5hf7:A, 4jgc:A, 5jxy:A, 2rba:A, 2rba:B, 5t2w:A, 6u15:A, 6u16:A, 6u17:A, 3ufj:B, 3ufj:A, 3uo7:A, 3uo7:B, 3uob:A, 3uob:B, 4xeg:A, 4z3a:A, 4z47:A, 4z7b:A, 4z7z:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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