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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
EKREAQVARETGETKIEVRLSLDGTGVSDVKTGIGFLDHMLSALAKHGRFDLYLRCAGDLHVDDHHTSEDCAIVLGQAFR
QAIGERKGIKRYGSAYAPLDESLARAVVDISSRPFAVIDLKLKREKIGELSCEMIPHVLHSFATSANLTLHVEVLYGAND
HHKAESAFKATALALREAVTKDGPADAVPSTKGVLE

The query sequence (length=196) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6fwh:A 196 196 1.0000 1.0000 1.0000 2.37e-143 6fwh:C, 6fwh:F, 6fwh:B, 6fwh:K, 6fwh:G, 6fwh:L, 6fwh:E, 6fwh:D, 6fwh:H, 6fwh:J, 6fwh:I
2 6ezm:U 212 213 0.6071 0.5613 0.5587 1.87e-83 6ezm:D, 6ezm:S, 6ezm:L, 6ezm:R, 6ezm:A, 6ezm:Q, 6ezm:V, 6ezm:O, 6ezm:B, 6ezm:N, 6ezm:F, 6ezm:T, 6ezm:C, 6ezm:X, 6ezm:E, 6ezm:H, 6ezm:P, 6ezm:J, 6ezm:G, 6ezm:I, 6ezm:W, 6ezm:K, 6ezm:M
3 1rhy:B 180 185 0.5357 0.5833 0.5676 8.31e-68
4 5el9:A 199 195 0.4694 0.4623 0.4718 1.39e-62 5ekw:A, 5elw:A, 6ezj:A, 6ezj:Q, 6ezj:B, 6ezj:N, 6ezj:C, 6ezj:W, 6ezj:D, 6ezj:H, 6ezj:E, 6ezj:R, 6ezj:F, 6ezj:G, 6ezj:V, 6ezj:L, 6ezj:I, 6ezj:S, 6ezj:J, 6ezj:K, 6ezj:U, 6ezj:X, 6ezj:M, 6ezj:P, 6ezj:O, 6ezj:T, 2f1d:B, 2f1d:A, 2f1d:G, 2f1d:C, 2f1d:D, 2f1d:E, 2f1d:F, 2f1d:H, 2f1d:J, 2f1d:I, 2f1d:O, 2f1d:K, 2f1d:L, 2f1d:M, 2f1d:N, 2f1d:P, 4mu0:A, 4mu1:A, 4mu3:A, 4mu4:A, 4qnj:A, 4qnk:A, 4qnk:B, 4qnk:C, 4qnk:D, 4qnk:E, 4qnk:F, 4qnk:G, 4qnk:H
5 8qaw:A 185 180 0.4133 0.4378 0.4500 5.52e-58 7oj5:A, 7oj5:B, 7oj5:C, 7oj5:D, 7oj5:E, 7oj5:F, 7oj5:G, 7oj5:H, 7oj5:I, 7oj5:J, 7oj5:K, 7oj5:L, 7oj5:M, 7oj5:N, 7oj5:O, 7oj5:P, 7oj5:Q, 7oj5:R, 7oj5:S, 7oj5:T, 7oj5:V, 7oj5:W, 7oj5:X, 7oj5:Y, 8qav:A, 8qav:S, 8qav:W, 8qav:B, 8qav:N, 8qav:R, 8qav:C, 8qav:Q, 8qav:V, 8qav:D, 8qav:H, 8qav:X, 8qav:E, 8qav:O, 8qav:Y, 8qav:F, 8qav:P, 8qav:G, 8qav:J, 8qav:M, 8qav:T, 8qav:I, 8qav:K, 8qav:L, 8qaw:B, 8qaw:C, 8qaw:D, 8qaw:E, 8qaw:F, 8qaw:G, 8qaw:H, 8qax:A, 8qax:B, 8qax:C, 8qax:D, 8qax:E, 8qax:F, 8qay:A, 8qay:B, 8qay:C, 8qay:D, 8qay:E, 8qay:F, 8qay:G, 8qay:H
6 4gqu:A 191 177 0.4082 0.4188 0.4520 1.69e-48 7ddv:A, 7dnq:A, 7fcy:A, 6khh:A, 4lom:A, 4lpf:A, 5xds:A, 6yjh:A, 5zqn:A
7 2ae8:B 172 158 0.3214 0.3663 0.3987 3.12e-39 2ae8:A, 2ae8:C, 2ae8:D, 2ae8:E, 2ae8:F
8 5dnl:A 176 187 0.3571 0.3977 0.3743 3.32e-29 5dnl:C, 5dnl:B, 5dnx:A, 5dnx:C, 5dnx:B
9 8bd3:Y 221 41 0.0816 0.0724 0.3902 4.7 8bd3:y
10 4oal:A 444 71 0.1020 0.0450 0.2817 7.1 4oal:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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