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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
EKLILALDQGTTSSRAILFNKSGEIKFVSQKSFEQIFPTPGWVEHDPNEIWSSQISVAAEVIAKAGLEVAAIGITNQRET
TVVWDRHTSEPIYNAIVWQDRRTSKYCDELKSQGHTDEIKQKTGLVLDAYFSATKLKWILDNVEGAREKAEAGDLCFGTV
DTWLIWKLTRGKMFITDVSNASRTMMFNIRTMDWDDDLLKLFNIPRAILPEVKQSSEVYGETSTTLFSTKIPIAGIAGDQ
QAALFGQMCTKPGMVKNTYGTGCFLLMNTGNEAVYSKNNLLTTVAWKINGEVSYALEGSVFVGGAAIQWLRDGLKIIHDS
SEVSTLAETVEDNGGVYFVPALTGLGAPYWDQYARGTIIGVTRGTTDGHIARATLEGIAFQVYDIVKAMEADAETQSTEL
RVDGGASASNLLMQIQSDLFGFKIIRPKTLETTALGAAYLAGLAVGFWESIDEIQSQWIIEKEFTPKEDKTKIDNMVSFW
HKAVKRSQAWIED

The query sequence (length=493) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6ude:B 495 496 0.9959 0.9919 0.9899 0.0 6ude:A, 6ude:C, 6ude:D
2 1bu6:Y 499 496 0.6045 0.5972 0.6008 0.0 1bo5:O, 1bo5:Z, 1bot:O, 1bot:Z, 1bu6:O, 1bu6:Z, 1bu6:X, 1bwf:Y, 1bwf:O, 3ezw:A, 3ezw:B, 3ezw:E, 3ezw:G, 3ezw:C, 3ezw:D, 3ezw:F, 3ezw:H, 1gla:G, 1glb:G, 1glc:G, 1gld:G, 1gle:G, 1glf:O, 1glf:X, 1glf:Y, 1glf:Z, 1glj:Y, 1glj:O, 1gll:Y, 1gll:O
3 3ge1:A 499 494 0.5801 0.5731 0.5789 0.0 3ge1:B, 3ge1:C, 3ge1:D
4 3h3n:X 501 491 0.5517 0.5429 0.5540 0.0 3d7e:O, 3d7e:X, 3flc:O, 3flc:X, 3h3n:O, 3h3o:O, 3h3o:X, 3h3o:B, 3h3o:C, 3h45:X, 3h45:O, 3h45:C, 3h45:D, 3h46:X, 3h46:O, 1xup:O, 1xup:X
5 6k76:A 485 489 0.5740 0.5835 0.5787 0.0 6k76:B
6 5azi:A 513 507 0.4523 0.4347 0.4398 4.05e-139 5azi:B, 5azi:C, 5azi:D, 5azj:A, 5azj:B, 5azj:C, 5azj:D, 5gn5:A, 5gn5:B, 5gn5:C, 5gn5:D, 5gn6:A, 5gn6:B, 5gn6:C, 5gn6:D, 6j9q:A, 6j9q:B, 6j9q:C, 6j9q:D, 6j9v:A, 6j9v:B, 6jaf:A, 3wxj:A, 3wxj:B, 3wxj:C, 3wxj:D, 3wxk:A, 3wxk:B, 3wxk:C, 3wxk:D, 3wxl:A, 3wxl:B, 3wxl:C, 3wxl:D
7 6zq4:F 512 511 0.4787 0.4609 0.4618 4.74e-135 6zq4:A, 6zq4:B, 6zq4:C, 6zq4:D, 6zq4:E, 6zq4:G, 6zq4:H, 6zq6:A, 6zq6:B, 6zq6:C, 6zq6:D, 6zq7:A
8 2w41:B 507 500 0.4097 0.3984 0.4040 1.80e-119 2w40:A, 2w40:B, 2w40:C, 2w40:D, 2w41:A
9 3ll3:A 492 483 0.2475 0.2480 0.2526 1.44e-34 3ll3:B
10 2itm:A 476 484 0.2272 0.2353 0.2314 1.75e-22 2itm:B
11 5ya1:A 478 492 0.2333 0.2406 0.2337 6.83e-20 5ya1:B, 5ya2:A, 5ya2:B
12 3kzb:A 498 469 0.2252 0.2229 0.2367 1.59e-12 3hz6:A
13 3i8b:A 506 532 0.2333 0.2273 0.2162 1.89e-07
14 3l0q:A 541 141 0.0710 0.0647 0.2482 5.73e-06
15 3l0q:A 541 146 0.0669 0.0610 0.2260 0.023
16 3qdk:A 546 130 0.0872 0.0788 0.3308 1.99e-05
17 2cgj:A 479 498 0.1947 0.2004 0.1928 3.55e-05 2cgl:A, 2uyt:A
18 5htv:A 424 456 0.1886 0.2193 0.2039 0.043 5htx:A
19 5xtc:b 124 45 0.0223 0.0887 0.2444 1.1 5xtd:b, 5xth:b, 5xti:b, 5xti:Bb
20 5euj:E 556 104 0.0568 0.0504 0.2692 1.1 5euj:A, 5euj:B, 5euj:C, 5euj:D, 5euj:F, 5euj:G, 5euj:H, 5euj:I, 5euj:J, 5euj:K, 5euj:L, 5euj:M, 5euj:N, 5euj:O, 5euj:P, 5euj:Q, 5euj:R, 5euj:S, 5euj:T, 5euj:U, 5euj:V, 5euj:W, 5euj:X
21 1jft:A 340 80 0.0406 0.0588 0.2500 2.1 1bdh:A, 1bdi:A, 1jfs:A, 1jh9:A, 1pnr:A, 2pua:A, 2pub:A, 2puc:A, 2pud:A, 2pue:A, 2puf:A, 2pug:A, 1qp0:A, 1qp4:A, 1qp7:A, 1qpz:A, 1qqa:A, 1qqb:A, 1vpw:A, 1wet:A, 1zay:A
22 8rh3:A 156 126 0.0751 0.2372 0.2937 3.5 8pqp:A, 8pqq:A, 8pqq:C, 8pqq:B, 8pqq:D, 8pqr:B, 8pqr:D, 8pqr:A, 8pqr:C, 8qc0:A, 8qc0:B, 8qc0:C, 8qc0:D, 8rh3:B, 8rh3:C, 8rh3:D
23 1n4p:B 346 53 0.0304 0.0434 0.2830 3.7 1n4p:D, 1n4p:F, 1n4p:H, 1n4p:J, 1n4p:L, 1n4q:B, 1n4q:D, 1n4q:F, 1n4q:H, 1n4q:J, 1n4q:L, 1n4r:B, 1n4r:D, 1n4r:F, 1n4r:H, 1n4r:J, 1n4r:L, 1n4s:B, 1n4s:D, 1n4s:F, 1n4s:H, 1n4s:L, 1n4s:J, 8rdx:B, 8rdx:D, 8rdx:F, 8rdx:H, 8rdx:J, 8rdx:L, 1s64:B, 1s64:D, 1s64:F, 1s64:H, 1s64:J, 1s64:L, 1tnb:B, 1tnb:D, 1tnb:F, 1tnb:H, 1tnb:J, 1tnb:L, 1tno:B, 1tno:D, 1tno:F, 1tno:H, 1tno:J, 1tno:L, 1tnu:B, 1tnu:D, 1tnu:F, 1tnu:H, 1tnu:J, 1tnu:L, 1tny:B, 1tny:D, 1tny:F, 1tny:H, 1tny:J, 1tny:L, 1tnz:B, 1tnz:D, 1tnz:F, 1tnz:H, 1tnz:J, 1tnz:L
24 7qsw:C 467 35 0.0284 0.0300 0.4000 5.5 7qsw:A, 7qsw:E, 7qsw:G
25 8uhi:A 465 35 0.0264 0.0280 0.3714 6.1 8uhi:B, 8uhi:C, 8uhi:D, 8uhi:E, 8uhi:F, 8uhi:G, 8uhi:H, 3zxw:A, 3zxw:C, 3zxw:E, 3zxw:G
26 4bc2:A 528 100 0.0588 0.0549 0.2900 7.7 4bc2:B, 4bc2:C, 4bc4:A, 4bc4:B, 4bc4:C, 4bc5:A, 4bc5:B, 4bc5:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218