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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
EKLILALDQGTTSSRAILFNKSGEIKFVSQKSFEQIFPTPGWVEHDPNEIWSSQISVAAEVIAKAGISGLEVAAIGITNQ
RETTVVWDRHTSEPIYNAIVWQDRRTSKYCDELKSQGHTDEIKQKTGLVLDAYFSATKLKWILDNVEGAREKAEAGDLCF
GTVDTWLIWKLTRGKMFITDVSNASRTMMFNIRTMDWDDDLLKLFNIPRAILPEVKQSSEVYGETSTTSTKIPIAGIAGD
QQAALFGQMCTKPGMVKNTYGTGCFLLMNTGNEAVYSKNNLLTTVAWKINGEVSYALEGSVFVGGAAIQWLRDGLKIIHD
SSEVSTLAETVEDNGGVYFVPALTGLGAPYWDQYARGTIIGVTRGTTDGHIARATLEGIAFQVYDIVKAMEADAETQSTE
LRVDGGASASNLLMQIQSDLFGFKIIRPKTLETTALGAAYLAGLAVGFWESIDEIQSQWIIEKEFTPKEDKTKIDNMVSF
WHKAVKRSQAWIED

The query sequence (length=494) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6ude:B 495 494 1.0000 0.9980 1.0000 0.0 6ude:A, 6ude:C, 6ude:D
2 1bu6:Y 499 496 0.6073 0.6012 0.6048 0.0 1bo5:O, 1bo5:Z, 1bot:O, 1bot:Z, 1bu6:O, 1bu6:Z, 1bu6:X, 1bwf:Y, 1bwf:O, 3ezw:A, 3ezw:B, 3ezw:E, 3ezw:G, 3ezw:C, 3ezw:D, 3ezw:F, 3ezw:H, 1gla:G, 1glb:G, 1glc:G, 1gld:G, 1gle:G, 1glf:O, 1glf:X, 1glf:Y, 1glf:Z, 1glj:Y, 1glj:O, 1gll:Y, 1gll:O
3 3ge1:A 499 494 0.5789 0.5731 0.5789 0.0 3ge1:B, 3ge1:C, 3ge1:D
4 3h3n:X 501 491 0.5506 0.5429 0.5540 0.0 3d7e:O, 3d7e:X, 3flc:O, 3flc:X, 3h3n:O, 3h3o:O, 3h3o:X, 3h3o:B, 3h3o:C, 3h45:X, 3h45:O, 3h45:C, 3h45:D, 3h46:X, 3h46:O, 1xup:O, 1xup:X
5 6k76:A 485 488 0.5709 0.5814 0.5779 0.0 6k76:B
6 5azi:A 513 507 0.4514 0.4347 0.4398 4.62e-139 5azi:B, 5azi:C, 5azi:D, 5azj:A, 5azj:B, 5azj:C, 5azj:D, 5gn5:A, 5gn5:B, 5gn5:C, 5gn5:D, 5gn6:A, 5gn6:B, 5gn6:C, 5gn6:D, 6j9q:A, 6j9q:B, 6j9q:C, 6j9q:D, 6j9v:A, 6j9v:B, 6jaf:A, 3wxj:A, 3wxj:B, 3wxj:C, 3wxj:D, 3wxk:A, 3wxk:B, 3wxk:C, 3wxk:D, 3wxl:A, 3wxl:B, 3wxl:C, 3wxl:D
7 6zq4:F 512 510 0.4798 0.4629 0.4647 6.42e-137 6zq4:A, 6zq4:B, 6zq4:C, 6zq4:D, 6zq4:E, 6zq4:G, 6zq4:H, 6zq6:A, 6zq6:B, 6zq6:C, 6zq6:D, 6zq7:A
8 2w41:B 507 500 0.4130 0.4024 0.4080 7.18e-121 2w40:A, 2w40:B, 2w40:C, 2w40:D, 2w41:A
9 3ll3:A 492 486 0.2510 0.2520 0.2551 8.77e-34 3ll3:B
10 5ya1:A 478 492 0.2348 0.2427 0.2358 4.20e-22 5ya1:B, 5ya2:A, 5ya2:B
11 2itm:A 476 486 0.2247 0.2332 0.2284 1.19e-21 2itm:B
12 3kzb:A 498 469 0.2206 0.2189 0.2324 1.93e-13 3hz6:A
13 3i8b:A 506 533 0.2389 0.2332 0.2214 1.10e-07
14 3l0q:A 541 141 0.0709 0.0647 0.2482 5.75e-06
15 3l0q:A 541 147 0.0688 0.0628 0.2313 2.24e-04
16 3qdk:A 546 303 0.1538 0.1392 0.2508 1.54e-05
17 2cgj:A 479 500 0.1964 0.2025 0.1940 5.90e-05 2cgl:A, 2uyt:A
18 5htv:A 424 458 0.1984 0.2311 0.2140 0.30 5htx:A
19 5xtc:b 124 45 0.0223 0.0887 0.2444 1.0 5xtd:b, 5xth:b, 5xti:b, 5xti:Bb
20 5euj:E 556 104 0.0567 0.0504 0.2692 1.2 5euj:A, 5euj:B, 5euj:C, 5euj:D, 5euj:F, 5euj:G, 5euj:H, 5euj:I, 5euj:J, 5euj:K, 5euj:L, 5euj:M, 5euj:N, 5euj:O, 5euj:P, 5euj:Q, 5euj:R, 5euj:S, 5euj:T, 5euj:U, 5euj:V, 5euj:W, 5euj:X
21 1jft:A 340 80 0.0405 0.0588 0.2500 2.2 1bdh:A, 1bdi:A, 1jfs:A, 1jh9:A, 1pnr:A, 2pua:A, 2pub:A, 2puc:A, 2pud:A, 2pue:A, 2puf:A, 2pug:A, 1qp0:A, 1qp4:A, 1qp7:A, 1qpz:A, 1qqa:A, 1qqb:A, 1vpw:A, 1wet:A, 1zay:A
22 8rh3:A 156 126 0.0749 0.2372 0.2937 3.2 8pqp:A, 8pqq:A, 8pqq:C, 8pqq:B, 8pqq:D, 8pqr:B, 8pqr:D, 8pqr:A, 8pqr:C, 8qc0:A, 8qc0:B, 8qc0:C, 8qc0:D, 8rh3:B, 8rh3:C, 8rh3:D
23 1n4p:B 346 53 0.0304 0.0434 0.2830 3.7 1n4p:D, 1n4p:F, 1n4p:H, 1n4p:J, 1n4p:L, 1n4q:B, 1n4q:D, 1n4q:F, 1n4q:H, 1n4q:J, 1n4q:L, 1n4r:B, 1n4r:D, 1n4r:F, 1n4r:H, 1n4r:J, 1n4r:L, 1n4s:B, 1n4s:D, 1n4s:F, 1n4s:H, 1n4s:L, 1n4s:J, 8rdx:B, 8rdx:D, 8rdx:F, 8rdx:H, 8rdx:J, 8rdx:L, 1s64:B, 1s64:D, 1s64:F, 1s64:H, 1s64:J, 1s64:L, 1tnb:B, 1tnb:D, 1tnb:F, 1tnb:H, 1tnb:J, 1tnb:L, 1tno:B, 1tno:D, 1tno:F, 1tno:H, 1tno:J, 1tno:L, 1tnu:B, 1tnu:D, 1tnu:F, 1tnu:H, 1tnu:J, 1tnu:L, 1tny:B, 1tny:D, 1tny:F, 1tny:H, 1tny:J, 1tny:L, 1tnz:B, 1tnz:D, 1tnz:F, 1tnz:H, 1tnz:J, 1tnz:L
24 6zha:A 3707 43 0.0263 0.0035 0.3023 5.4 6zh8:A
25 7qsw:C 467 35 0.0283 0.0300 0.4000 5.4 7qsw:A, 7qsw:E, 7qsw:G
26 7nfe:A 3585 43 0.0263 0.0036 0.3023 5.5
27 7otm:A 3656 43 0.0263 0.0036 0.3023 5.5 7otp:A, 7otv:A, 7otw:A, 7oty:A
28 8bot:A 3528 43 0.0263 0.0037 0.3023 5.6
29 6zhe:A 3768 43 0.0263 0.0035 0.3023 5.6
30 8ez9:L 3662 43 0.0263 0.0035 0.3023 5.6 8ez9:C
31 7k17:B 3645 43 0.0263 0.0036 0.3023 5.7 7k17:A
32 7k0y:A 3669 43 0.0263 0.0035 0.3023 5.7
33 7k1j:A 3584 43 0.0263 0.0036 0.3023 5.7 7k19:A
34 7z87:A 3689 43 0.0263 0.0035 0.3023 5.8
35 8ezb:C 3724 43 0.0263 0.0035 0.3023 5.8 8ezb:L
36 7sud:A 3740 43 0.0263 0.0035 0.3023 5.8
37 7k1n:A 3634 43 0.0263 0.0036 0.3023 5.8 7z88:A
38 6zhe:F 3731 43 0.0263 0.0035 0.3023 5.8
39 7su3:A 3802 43 0.0263 0.0034 0.3023 5.8
40 7nfc:A 3562 43 0.0263 0.0036 0.3023 5.9 8bh3:S, 8bh3:A, 8bhv:A, 8bhv:F, 8bhy:A, 8bhy:S, 8bot:F, 8bot:S, 7nfc:F
41 7k1k:A 3604 43 0.0263 0.0036 0.3023 5.9 7k1b:A
42 8eza:L 3720 43 0.0263 0.0035 0.3023 5.9 8eza:C, 7lt3:C, 7lt3:L
43 5y3r:C 3636 43 0.0263 0.0036 0.3023 6.0
44 8uhi:A 465 35 0.0263 0.0280 0.3714 6.1 8uhi:B, 8uhi:C, 8uhi:D, 8uhi:E, 8uhi:F, 8uhi:G, 8uhi:H, 3zxw:A, 3zxw:C, 3zxw:E, 3zxw:G
45 7sgl:A 3852 43 0.0263 0.0034 0.3023 6.2
46 4bc2:A 528 100 0.0587 0.0549 0.2900 8.0 4bc2:B, 4bc2:C, 4bc4:A, 4bc4:B, 4bc4:C, 4bc5:A, 4bc5:B, 4bc5:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218