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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
EKKLFLKALKKKFEGEDPEEKSTNFYCFGGWEQSERKREFTEYAKKAAEKRGGIPFYNPDIGVPLGQRKLMAYRVSGTDA
YVEGDDLHFVNNAAIQQMVDDIKRTVIVGMDTAHAVLEKRLGVEVTPETINEYMEVINHALPGGAVVQEHMVEVHPGIVE
DCYAKVFTGDDNLADELDKRILIDINKEFPEEQAEQLKSYIGNRTYQVNRVPTIVVRACDGGTVSRWSAMQIGMSFISAY
KLCAGEAAIADFSFAAKHADVIEMGTIMPARRARGPNEPGGVAFGTFADIVQASRVSDDPANVSLEVIAGAAALYDQVWL
GSYMSGGVGFTQYATAAYTDDILDDFLYYGMEYVEDKFGICGSEPTMDVVRDISTEVTLYSLEQYEEYPTLLEDHFGGSQ
RAAVAAAAAGCSTAFATGNSNAGVNGWYLSQILHKEAHSRLGFYGYDLQDQCGASNSLSIRSDEGLIHELRGPNYPNYAM
NVGHQPEYAGIAQAPHAARGDAFCTNPLIKVAFADKDLSFDFTSPRKSIAKGALREFIPEGERDLIIPA

The query sequence (length=549) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5a8w:D 549 549 1.0000 1.0000 1.0000 0.0 5a8r:A, 5a8r:D, 5a8r:G, 5a8r:J, 5a8w:A, 5a8w:G, 5a8w:J
2 5n1q:A 549 549 0.7905 0.7905 0.7905 0.0 5n1q:D, 5n28:A, 5n28:D, 5n2a:A
3 1e6v:A 545 547 0.7505 0.7560 0.7532 0.0 1e6v:D
4 5a0y:A 548 548 0.7250 0.7263 0.7263 0.0 5a0y:D, 5a8k:A, 5a8k:D, 7b2h:A, 7b2h:D, 5g0r:A, 5g0r:D, 1hbm:A, 1hbm:D, 1hbn:A, 1hbn:D, 1hbo:A, 1hbo:D, 1hbu:A, 1hbu:D, 3m1v:A, 3m1v:D, 3m2r:A, 3m2r:D, 3m2u:A, 3m2u:D, 3m2v:A, 3m2v:D, 3m30:A, 3m30:D, 3m32:A, 3m32:D, 1mro:A, 1mro:D, 3pot:A, 3pot:D, 7suc:A, 7suc:a, 7sxm:A, 7sxm:D
5 1e6y:A 568 548 0.6375 0.6162 0.6387 0.0 1e6y:D, 8gf5:A, 8gf5:B
6 7nkg:D 565 563 0.6758 0.6566 0.6590 0.0 7nkg:A, 7nkg:G, 7nkg:J
7 3sqg:A 578 559 0.5355 0.5087 0.5259 0.0 3sqg:D, 3sqg:G
8 7b1s:D 593 589 0.4718 0.4368 0.4397 2.42e-166 7b1s:A, 7b2c:A, 7b2c:D
9 2q3r:A 351 95 0.0437 0.0684 0.2526 0.61 1vji:A
10 5l9c:A 304 124 0.0619 0.1118 0.2742 5.9 5l9c:B, 5l9c:C, 5l9c:D
11 2c43:A 280 26 0.0200 0.0393 0.4231 6.4 2cg5:A
12 6e20:B 133 34 0.0255 0.1053 0.4118 7.4 6e20:A
13 1o0s:A 602 189 0.0656 0.0598 0.1905 7.7 1llq:A, 1llq:B, 1o0s:B
14 6dzs:A 431 63 0.0364 0.0464 0.3175 8.0 6dzs:B, 6dzs:C, 6dzs:D
15 2vq3:A 181 87 0.0474 0.1436 0.2989 8.2 2vq3:B
16 2yjz:A 174 69 0.0455 0.1437 0.3623 9.7 2yjz:B, 2yjz:C, 2yjz:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218