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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
EKKLFLKALKEKFEEDPKEKYTKFYVFGGWRQSARKREFVEAAEKLAEKRGGIPFYNPDIGVPLGQRKLMPYKLSGTDYI
VEGDDLHFMNNAAMQQFWDDIRRTVIVGMDTAHAVLEKRLGVEVTPETINEYMETINHALPGGAVVQEHMVEVHPALAWD
CYAKIFTGDDELADEIDKKFLIDINKLFPEEQAEQLKAAIGKRTYQVSRVPTLVGRVCDGGTIARWSAMQIGMSFITAYK
LCAGEAAIADFSYAAKHADVIQMGTLLPARRARGPNEPGGIPFGILADVVQTTRVSDDPVEQSLEVVASGAMLYDQIWLG
SYMSGGVGFTQYATASYTDDILDDFSYYGYDYVEKKYGICGAKPTMDVVEDIATEVTLYALECYDEFPALLEDHFGGSQR
AAVAAAASGISVCMATGNSNAGLNGWYLSQILHKEYHSRLGFYGYDLQDQCGASNSLSIRNDESSPLELRGPNYPNYAMN
VGHQGEYAGITQAAHSARKDAFALNPLIKVAFADPSLVFDFSHPRKEFARGALREFEPAGERDPIIPA

The query sequence (length=548) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5n1q:A 549 548 0.9142 0.9126 0.9142 0.0 5n1q:D, 5n28:A, 5n28:D, 5n2a:A
2 5a8w:D 549 534 0.7828 0.7814 0.8034 0.0 5a8r:A, 5a8r:D, 5a8r:G, 5a8r:J, 5a8w:A, 5a8w:G, 5a8w:J
3 1e6v:A 545 546 0.7628 0.7670 0.7656 0.0 1e6v:D
4 5a0y:A 548 547 0.7245 0.7245 0.7258 0.0 5a0y:D, 5a8k:A, 5a8k:D, 7b2h:A, 7b2h:D, 5g0r:A, 5g0r:D, 1hbm:A, 1hbm:D, 1hbn:A, 1hbn:D, 1hbo:A, 1hbo:D, 1hbu:A, 1hbu:D, 3m1v:A, 3m1v:D, 3m2r:A, 3m2r:D, 3m2u:A, 3m2u:D, 3m2v:A, 3m2v:D, 3m30:A, 3m30:D, 3m32:A, 3m32:D, 1mro:A, 1mro:D, 3pot:A, 3pot:D, 7suc:A, 7suc:a, 7sxm:A, 7sxm:D
5 1e6y:A 568 542 0.6478 0.6250 0.6550 0.0 1e6y:D, 8gf5:A, 8gf5:B
6 7nkg:D 565 563 0.6788 0.6584 0.6607 0.0 7nkg:A, 7nkg:G, 7nkg:J
7 3sqg:A 578 558 0.5474 0.5190 0.5376 0.0 3sqg:D, 3sqg:G
8 7b1s:D 593 590 0.4854 0.4486 0.4508 4.59e-171 7b1s:A, 7b2c:A, 7b2c:D
9 2q3r:A 351 95 0.0420 0.0655 0.2421 0.72 1vji:A
10 2c43:A 280 29 0.0201 0.0393 0.3793 2.6 2cg5:A
11 5szl:C 418 128 0.0566 0.0742 0.2422 2.8 5szl:A, 5szl:B, 5szl:D, 4zi9:A, 4zi9:B
12 6s32:D 352 76 0.0420 0.0653 0.3026 5.5 6s32:A, 6s32:B, 6s32:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218