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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
EIRLGLPSKGRMSSDTLDLLKDCQLSVRQYVAQIPQISNLEVWFQRPKDIVRKLLSGDLDLGIVGLDVLTEFGQGNEDLI
VVHEALEYGDCRLSIAIPQKMPQWTEDLRVATGFTYLGPKFMKDNGHVAFSTAALEAAPAMGIAILDLVSSGTTLKENNL
KEIEGGTVLESQAALVASRRSMIGRKGVLETTHEMLERLEAHLRAMGQFTVVANMRGSSAEEVAERVLSQPSLAGLQGPT
VSPVFCKRDGKVSADYYAIVICVPKKALYKSIQQLRAIGGSGVLVSPLTYIFDEETPRWRQLLSKLG

The query sequence (length=307) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6czm:E 342 334 1.0000 0.8977 0.9192 0.0 6czm:A, 6czm:C, 6czm:D
2 6czm:F 315 322 0.9577 0.9333 0.9130 0.0 6czm:B
3 2vd3:A 289 309 0.3290 0.3495 0.3269 5.98e-31 2vd3:B
4 4yb6:A 296 306 0.2801 0.2905 0.2810 9.43e-22 5ub9:A, 5ub9:B, 5ubg:A, 5ubg:B, 5ubh:A, 5ubh:B, 5ubi:A, 5ubi:B, 4yb5:A, 4yb5:E, 4yb5:B, 4yb5:C, 4yb5:F, 4yb5:D, 4yb6:E, 4yb6:B, 4yb6:C, 4yb6:F, 4yb6:D, 4yb7:B, 4yb7:C, 4yb7:D, 4yb7:E, 4yb7:I, 4yb7:K, 4yb7:A, 4yb7:F, 4yb7:G, 4yb7:H, 4yb7:J, 4yb7:L
5 1h3d:A 288 312 0.2541 0.2708 0.2500 2.28e-21 1q1k:A
6 7dah:C 288 312 0.2932 0.3125 0.2885 5.30e-21 7dah:F
7 5lht:A 284 301 0.2671 0.2887 0.2724 1.23e-16 5lhu:A, 1nh8:A, 5u99:A
8 6fca:A 209 168 0.1498 0.2201 0.2738 7.10e-08 6fct:A, 6fcw:A, 6fcy:A, 6fd9:A, 6ftt:E, 6ftt:H, 6ftt:G, 6ftt:F, 6fu2:C, 6fu2:D, 6fu7:C, 6fu7:D, 6fua:C, 6fua:D, 6r02:E, 6r02:F, 6r02:G, 6r02:H, 7z6r:C, 7z6r:D, 7z8u:A
9 1usy:G 203 204 0.1596 0.2414 0.2402 8.90e-08 1usy:F, 1usy:E, 1usy:H
10 1z7n:F 205 171 0.1466 0.2195 0.2632 2.05e-07 1z7m:G, 1z7m:E, 1z7m:H, 1z7n:E, 1z7n:G, 1z7n:H
11 3aib:G 844 136 0.0912 0.0332 0.2059 0.76 3aib:A, 3aib:B, 3aib:C, 3aib:D, 3aib:E, 3aib:F, 3aib:H, 3aic:A, 3aic:B, 3aic:C, 3aic:D, 3aic:E, 3aic:F, 3aic:G, 3aic:H, 3aie:A, 3aie:B, 3aie:C, 3aie:D, 3aie:E, 3aie:F, 3aie:G, 3aie:H, 8fg8:A, 8fg8:B, 8fj9:A, 8fj9:B, 8fjc:A, 8fjc:B, 8fk4:A, 8fk4:B, 8fk4:C, 8fk4:D, 8fk4:E, 8fk4:F, 8fk4:G, 8fk4:H, 8uf5:A, 8uf5:B
12 7edd:A 1394 68 0.0554 0.0122 0.2500 2.8 5xyr:A
13 5xxz:B 1310 68 0.0554 0.0130 0.2500 3.1
14 6vjb:A 1346 50 0.0456 0.0104 0.2800 4.6
15 4zsi:A 166 84 0.0847 0.1566 0.3095 5.1 4zsi:B, 4zsk:A, 4zsk:B
16 5xya:A 1358 68 0.0554 0.0125 0.2500 7.3 5xxz:A
17 3h0l:A 478 44 0.0423 0.0272 0.2955 7.6 3h0l:D, 3h0l:G, 3h0l:J, 3h0l:M, 3h0l:P, 3h0l:S, 3h0l:V, 3h0m:A, 3h0m:D, 3h0m:G, 3h0m:J, 3h0m:M, 3h0m:P, 3h0m:S, 3h0m:V, 3h0r:A, 3h0r:D, 3h0r:G, 3h0r:J, 3h0r:M, 3h0r:P, 3h0r:S, 3h0r:V
18 7pua:Fi 475 74 0.0684 0.0442 0.2838 8.9
19 5csu:A 518 52 0.0521 0.0309 0.3077 9.6 5cps:A, 5cps:B, 5cpt:A, 5cpt:B, 5cq1:A, 5cq1:B, 5csu:B, 5csy:A, 5csy:B
20 6pej:A 257 65 0.0586 0.0700 0.2769 9.9 6pej:B, 6pej:C, 6pej:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218