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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
EIQIIPTHSSDEEANLFAMQLASAAVLPMALKAAIELDVLEIMAKSVPPSGYISPAEIAAQLPTTNPEAPVMLDRVLRLL
ASYSVVTYTLRELPSGKVERLYGLAPVCKFLTKNEDGVSLAPFLLLATDKVLLEPWFYLKDAILEGGIPFNKAYGMNIWD
YFGTDHRINKVFNKGMSSNSTITMKKILEMYNGFEGLTTIVDVGGGTGAVASMIVAKYPSINAINFDLPHVIQDAPAFSG
VEHLGGDMFDGVPKGDAIFIKWICHDWSDEHCLKLLKNCYAALPDHGKVIVAEYILPPSPDPSIATKVVIHTDALMLAYN
PGGKERTEKEFQALAMASGFRGFKVASCAFNTYVMEFLKTA

The query sequence (length=361) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5cvj:D 361 361 1.0000 1.0000 1.0000 0.0 5cvj:A, 5cvj:B, 5cvj:C, 5cvu:A, 5cvu:B, 5cvu:C, 5cvu:D, 5cvv:A, 5cvv:B, 3reo:A, 3reo:B, 3reo:C, 3reo:D, 3tky:A, 3tky:B, 3tky:C, 3tky:D
2 6i71:A 353 350 0.7202 0.7365 0.7429 0.0 6i71:B, 6i72:A, 6i72:B, 6i73:A, 6i73:B, 6yjw:A, 6yjw:B
3 1kyw:C 361 359 0.7008 0.7008 0.7047 0.0 1kyw:F, 1kyz:A, 1kyz:C, 1kyz:E
4 7v6l:B 347 349 0.6371 0.6628 0.6590 7.58e-177 7v6j:A, 7v6j:B, 7v6l:A
5 5xoh:A 348 348 0.5873 0.6092 0.6092 2.07e-158
6 3p9i:A 357 352 0.5734 0.5798 0.5881 2.04e-154 3p9c:A, 3p9i:B, 3p9i:C, 3p9i:D, 3p9k:A, 3p9k:B, 3p9k:C, 3p9k:D
7 4pgh:D 358 354 0.5402 0.5447 0.5508 9.28e-137 4pgh:A, 4pgh:B, 4pgh:C
8 1fp1:D 340 354 0.4543 0.4824 0.4633 2.61e-110 1fpq:A
9 6nej:B 346 345 0.4211 0.4393 0.4406 2.07e-101 6neg:A, 6neg:B, 6neh:A, 6neh:B, 6nej:A
10 7waq:D 365 364 0.4266 0.4219 0.4231 1.03e-96 7vb8:B, 7vb8:A, 7waq:B, 7waq:A, 7waq:C, 7war:B, 7war:A, 7was:A, 7was:B
11 6i6m:B 357 351 0.4072 0.4118 0.4188 2.73e-89 6i5z:A, 6i5z:B, 6i5z:D, 6i6k:A, 6i6k:B, 6i6l:A, 6i6l:B, 6i6m:A, 6i6n:A, 6i6n:B
12 5icc:A 352 334 0.3546 0.3636 0.3832 1.85e-66 5ice:A, 5icf:A
13 6cig:A 349 333 0.2742 0.2837 0.2973 3.56e-46 1fp2:A
14 2qyo:A 353 335 0.2742 0.2805 0.2955 7.33e-44 2qyo:B
15 4evi:A 360 334 0.2687 0.2694 0.2904 1.09e-39 4e70:A, 4e70:B, 4evi:B
16 6c5b:A 332 346 0.2687 0.2922 0.2803 7.77e-35 6c5b:B
17 1zg3:A 358 354 0.3047 0.3073 0.3107 1.02e-32 1zga:A, 1zgj:A, 1zhf:A
18 3lst:A 333 295 0.2216 0.2402 0.2712 4.07e-23 3lst:B
19 3gwz:A 339 221 0.1662 0.1770 0.2715 4.73e-23 3gwz:D, 3gwz:C, 3gwz:B, 3gxo:A, 3gxo:D, 3gxo:C, 3gxo:B
20 6clx:B 342 212 0.1579 0.1667 0.2689 3.10e-20 6clx:A
21 8bie:A 318 197 0.1468 0.1667 0.2690 9.38e-19 8bie:B, 8bij:A, 8bij:B
22 4a6d:A 345 217 0.1579 0.1652 0.2627 3.45e-17 4a6e:A
23 8bic:B 323 193 0.1468 0.1641 0.2746 4.09e-17 8bic:A
24 8bif:A 318 212 0.1440 0.1635 0.2453 1.69e-15 8bif:B, 8bif:C, 8bif:D
25 8bir:A 321 216 0.1413 0.1589 0.2361 8.42e-14 8big:A, 8big:B, 8big:C, 8big:D, 8big:E, 8big:F, 8big:G, 8big:H, 8bii:A, 8bii:B, 8bii:C, 8bii:D, 8bii:E, 8bii:F, 8bii:G, 8bii:H, 8bir:B
26 8bgt:A 319 196 0.1330 0.1505 0.2449 4.19e-13 8bgt:B, 8bgx:A, 8bgx:B, 8bgx:C, 8bgx:D, 8bgy:A, 8bgy:B, 8bgy:C, 8bgy:D, 8bgz:A, 8bgz:B, 8bgz:C, 8bgz:D, 8bh0:A, 8bh0:B, 8bh0:C, 8bh0:D, 8bh0:E, 8bh0:F, 8bh0:G, 8bh0:H, 8bib:A, 8bib:B, 8bib:C, 8bib:D, 8bid:A, 8bid:B, 8bid:C, 8bid:D, 8bih:A, 8bih:B, 8bih:C, 8bih:D, 8bih:E, 8bih:F, 8bih:G, 8bih:H, 8bih:I, 8bih:J, 8bih:K, 8bih:L
27 1qzz:A 340 232 0.1551 0.1647 0.2414 9.20e-12 1r00:A, 1xds:A, 1xds:B, 1xdu:A
28 8pha:A 450 246 0.1690 0.1356 0.2480 5.27e-11 8pha:B
29 5i2h:A 335 105 0.0914 0.0985 0.3143 1.29e-10 5i2h:B
30 8tjj:C 330 234 0.1634 0.1788 0.2521 3.19e-10 8tjj:A, 8tjj:B, 8tjj:D, 8tjk:A, 8tjk:B
31 7y3h:A 396 155 0.1413 0.1288 0.3290 8.41e-10 8gx4:A, 8gzi:A
32 7pg7:D 329 201 0.1357 0.1489 0.2438 1.18e-09
33 6inw:B 390 169 0.1302 0.1205 0.2781 2.88e-09 6inw:A, 6iv7:A, 6iv7:B, 6ix3:A, 6ix3:B, 6ix5:A, 6ix5:B, 6ix7:A, 6ix7:B, 6ix8:A, 6ix8:B, 6ix9:A, 6ix9:B, 6j1o:A, 6j1o:B, 6j24:B, 6j24:A, 6j46:A, 6j46:B, 5zzd:A, 5zzd:B
34 7clf:A 335 165 0.1247 0.1343 0.2727 1.86e-08 7clf:B
35 7wuy:A 393 154 0.1163 0.1069 0.2727 2.13e-07 7wuy:B, 7wvs:A, 7wvs:B, 7ww0:A, 7ww0:B
36 7wh9:A 476 169 0.0997 0.0756 0.2130 4.70e-07 7wh9:B, 7wh9:C
37 1tw2:B 350 210 0.1330 0.1371 0.2286 1.13e-06 5eeg:A, 5eeg:B, 5eeh:A, 5eeh:B, 5eeh:C, 5jr3:A, 5jr3:B, 5jr3:C, 7owb:A, 7oy1:A, 7oy1:B, 7pga:A, 7pga:B, 7pga:C, 7pga:D, 7pgj:A, 7phd:A, 7phd:B, 7phe:A, 7phe:B, 7phf:A, 7phf:D, 7phf:C, 1tw2:A, 1tw3:A, 1tw3:B, 4wxh:A, 4wxh:B
38 8har:A 357 108 0.0942 0.0952 0.3148 8.90e-06 8har:B
39 1x1a:A 337 285 0.1662 0.1780 0.2105 1.22e-05 1x1b:A, 1x1c:A, 1x1d:A
40 5w7p:A 396 158 0.1219 0.1111 0.2785 1.28e-05 5w7r:A, 5w7s:A
41 8xte:A 395 166 0.1163 0.1063 0.2530 2.02e-05 8xte:B, 8xte:C, 8xte:D, 8xte:E, 8xte:F, 8xtf:A, 8xtg:A, 8xtg:B, 8xtg:C, 8xtg:D, 8xtg:E, 8xtg:F
42 4u1q:A 341 133 0.1025 0.1085 0.2782 2.24e-05 4u1q:B, 4u1q:C, 4u1q:D, 4x3q:A, 4x3q:B, 4x3q:C, 4x3q:D
43 7bqk:A 459 209 0.1468 0.1155 0.2536 5.19e-05 7bqk:B, 7bql:A, 7bql:B
44 7bqo:A 451 171 0.1163 0.0931 0.2456 1.59e-04
45 3i58:A 328 96 0.0859 0.0945 0.3229 1.78e-04 3i53:A, 3i53:B, 3i58:B, 3i5u:A, 3i5u:B, 3i64:A, 3i64:B
46 7wdq:A 336 237 0.1413 0.1518 0.2152 0.001 7wdq:B, 7wdq:C, 7wdw:A, 7wdw:B, 7wdw:C, 7wdw:D
47 7ux7:A 378 170 0.1025 0.0979 0.2176 0.002 7ux6:A, 7ux6:B, 7ux7:B, 7ux8:A, 7ux8:B
48 3dtn:A 220 103 0.0748 0.1227 0.2621 0.023 3dtn:B
49 7phf:B 270 94 0.0693 0.0926 0.2660 0.025
50 9fce:B 209 104 0.0748 0.1292 0.2596 0.038 9fce:A
51 6dtn:B 233 108 0.0582 0.0901 0.1944 0.20 5cvd:A, 5cvd:B, 5cve:A, 5cve:B, 5e1b:A, 5e1b:B, 5e1d:A, 5e1d:B, 5e1m:A, 5e1m:B, 5e1o:A, 5e1o:B, 5e2a:A, 5e2a:B, 5e2b:A, 5e2b:B, 2ex4:A, 2ex4:B, 7k3d:B, 7k3d:A, 6kdq:A, 6kdq:B, 6pva:B, 6pvb:B, 7ss1:A, 7ss1:B, 7u1m:A, 7u1m:B, 6wh8:B, 6wh8:A, 6wj7:B
52 6wlf:B 434 152 0.0831 0.0691 0.1974 0.25 6wlf:A
53 4kif:B 339 116 0.0720 0.0767 0.2241 0.44 4kib:A, 4kib:B, 4kic:A, 4kic:B, 4kif:A, 4kig:A, 4kig:B, 4m6x:A, 4m6x:B, 4m6y:A, 4m6y:B, 4m71:A, 4m71:B, 4m72:A, 4m72:B, 4m73:A, 4m73:B, 4m74:A, 4m74:B
54 2v7y:A 504 82 0.0609 0.0437 0.2683 0.49
55 2ics:A 368 67 0.0499 0.0489 0.2687 0.69
56 5m58:A 230 70 0.0526 0.0826 0.2714 0.72 5m58:B
57 7d8f:A 234 107 0.0693 0.1068 0.2336 1.5 7d8d:A
58 5x4z:N 1074 77 0.0637 0.0214 0.2987 1.6 5x4z:B, 5x51:B, 5x51:N
59 3ftf:A 246 50 0.0499 0.0732 0.3600 1.7 3fte:A, 3r9x:B
60 4ng4:B 389 87 0.0720 0.0668 0.2989 2.7 4ng4:A, 4ng4:C
61 7xn7:B 1164 58 0.0554 0.0172 0.3448 2.9 6a5l:B, 6a5o:B, 6a5p:B, 6a5r:B, 6a5t:B, 6a5u:B, 8h0v:B, 8h0w:B, 8he5:B, 6inq:B, 6ir9:B, 6j4w:B, 6j4x:B, 6j4y:B, 6j4z:B, 6j50:B, 6j51:B, 8jh2:B, 8jh3:B, 8jh4:B, 7wbv:B, 7wbw:B, 7wbx:B, 5xog:B, 5xon:B, 7xse:B, 7xsx:B, 7xsz:B, 7xt7:B, 7xtd:B, 7xti:B, 8yfq:B, 8yfr:B
62 1xtp:A 246 148 0.0886 0.1301 0.2162 4.1
63 5mgz:A 230 30 0.0277 0.0435 0.3333 4.3 5mgz:B
64 5c4j:B 1157 78 0.0609 0.0190 0.2821 4.6 4a3b:B, 4a3c:B, 4a3d:B, 4a3e:B, 4a3f:B, 4a3g:B, 4a3i:B, 4a3j:B, 4a3k:B, 4a3l:B, 4a3m:B, 4a93:B, 2b63:B, 2b8k:B, 6blo:B, 6blp:B, 6bm2:B, 6bm4:B, 6bqf:B, 4by1:B, 4by7:B, 2e2j:B, 3gtl:B, 3gtm:B, 3gto:B, 3gtp:B, 3gtq:B, 3h3v:C, 3hou:B, 3hou:N, 3hov:B, 3how:B, 3hox:B, 3hoy:B, 3hoz:B, 6i84:B, 3j0k:B, 2ja5:B, 2ja6:B, 2ja7:B, 2ja7:N, 2ja8:B, 7ked:B, 7kee:B, 7kef:B, 3m3y:B, 3m4o:B, 7ml4:B, 7nkx:B, 7nky:B, 2nvq:B, 2nvt:B, 2nvx:B, 5ot2:B, 3po3:B, 3qt1:B, 2r7z:B, 1r9t:B, 2r92:B, 2r93:B, 7riq:B, 7riw:B, 7rix:B, 7riy:B, 3rzd:B, 3rzo:B, 3s14:B, 3s15:B, 3s16:B, 3s17:B, 3s1m:B, 3s1n:B, 3s1q:B, 3s1r:B, 3s2d:B, 3s2h:B, 1sfo:B, 8ukq:B, 8ukr:B, 8uks:B, 8ukt:B, 8uku:B, 6upx:B, 6upz:B, 6uq0:B, 6uq1:B, 6uq2:B, 6uq3:B, 2vum:B, 4x67:B, 4x6a:B, 1y1v:B, 1y1w:B, 4y52:B, 1y77:B, 4y7n:B
65 4bxx:B 1097 78 0.0609 0.0201 0.2821 4.7 4bxz:B, 3cqz:B, 1i3q:B, 1i50:B, 1i6h:B, 1k83:B, 1nik:B, 2nvy:B, 1r5u:B, 1r9s:B, 1twa:B, 1twc:B, 1twf:B, 1twg:B, 1twh:B, 5w4u:B, 5w51:B, 1wcm:B
66 8cen:B 1180 78 0.0609 0.0186 0.2821 4.9 4bbr:B, 4bbs:B, 5c3e:B, 5c4a:B, 5c4x:B, 8ceo:B, 2e2i:B, 3fki:B, 5fmf:B, 5fyw:B, 5fz5:B, 6gyk:B, 6gyl:B, 6gym:B, 3i4m:B, 3i4n:B, 5ip7:B, 5ip9:B, 3k1f:B, 7mei:b, 7mei:B, 7mk9:B, 7mka:b, 7ml0:B, 7ml1:B, 7ml2:B, 7o4i:B, 7o4j:B, 7o72:B, 7o73:B, 7o75:B, 5oqj:B, 5oqm:B, 3po2:B, 7rim:B, 7rip:B, 5sva:B, 4v1m:B, 4v1n:B, 4v1o:B, 7zs9:B, 7zsa:B, 7zsb:B
67 3k7a:B 1122 78 0.0609 0.0196 0.2821 4.9
68 6o6c:B 1165 78 0.0609 0.0189 0.2821 5.1 5c44:B, 2e2h:B, 9ja1:B, 2nvz:B, 6upy:B, 2yu9:B
69 8u9r:B 1060 60 0.0526 0.0179 0.3167 5.5 8u9x:B
70 8tvy:B 1207 78 0.0609 0.0182 0.2821 5.6 3gtg:B, 3gtj:B, 3gtk:B, 8jch:B, 8k5p:B, 7o4k:B, 7o4l:B, 5u5q:B, 5vvr:B, 5vvs:B
71 8tug:B 1041 60 0.0526 0.0183 0.3167 5.9 8tvp:B, 8tvq:B, 8tvs:B, 8tvv:B, 8tvw:B, 8tvx:B
72 1t5j:A 301 102 0.0693 0.0831 0.2451 7.5
73 4dzr:A 163 66 0.0416 0.0920 0.2273 9.5

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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