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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
EIGRTTDPVRMYMREMGTVELLTREGEIDIAKRIEDGINQVQCSVAEYPEAITYLLEQYDRVEAEEARLSDLITGFELAR
EKFAELRAQYVVTRDTIKAHATAQEEILKLSEVFKQFRLVPKQFDYLVNSMRVMMDRVRTQERLIMKLCVEQCKMPKKNF
ITLFTGNETSDTWFNAAIAMNKPWSEKLHDVSEEVHRALQKLQQIEEETGLTIEQVKDINRRMSIGEAKARRAKKEMVEA
NLRLVISIAKKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQATAREAKVLRMRFGID
MNTDYTLEEVGKQFDVTRERIRQIEAKALRKLR

The query sequence (length=353) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7ubm:F 353 353 1.0000 1.0000 1.0000 0.0 7ubn:F
2 6n4c:F 558 320 0.8640 0.5466 0.9531 0.0 8ad1:F, 6b6h:F, 7bef:F, 7beg:F, 7c17:F, 7c97:F, 6ca0:F, 7chw:F, 7dy6:F, 8ftd:L, 6jnx:F, 8jo2:F, 6k4y:F, 7khb:F, 7khc:F, 7khe:F, 7khi:F, 6ldi:F, 7mkd:L, 7mke:L, 7mki:L, 7mkj:L, 7n4e:F, 6n57:L, 6n62:F, 6oul:L, 6p18:F, 2p7v:B, 6pb4:F, 6pb5:F, 6pb6:F, 6psq:L, 6pss:L, 6pst:L, 6psu:L, 6psv:L, 6psw:L, 7szj:F, 8to1:L, 8to6:L, 8to8:L, 8toe:L, 8tom:L, 5vt0:L, 7vwy:F, 7vwz:F, 7w5w:F, 7w5x:F, 7w5y:F, 6wmu:F, 6xh7:F, 6xh8:F, 6xl5:F, 6xl9:F, 6xlj:F, 6xll:F, 8y6u:F, 4yln:F, 4yln:L, 4yln:R, 4ylo:F, 4ylo:L, 4ylo:R, 4ylp:F, 4ylp:L, 4ylp:R
3 6n4c:F 558 68 0.1501 0.0950 0.7794 1.29e-23 8ad1:F, 6b6h:F, 7bef:F, 7beg:F, 7c17:F, 7c97:F, 6ca0:F, 7chw:F, 7dy6:F, 8ftd:L, 6jnx:F, 8jo2:F, 6k4y:F, 7khb:F, 7khc:F, 7khe:F, 7khi:F, 6ldi:F, 7mkd:L, 7mke:L, 7mki:L, 7mkj:L, 7n4e:F, 6n57:L, 6n62:F, 6oul:L, 6p18:F, 2p7v:B, 6pb4:F, 6pb5:F, 6pb6:F, 6psq:L, 6pss:L, 6pst:L, 6psu:L, 6psv:L, 6psw:L, 7szj:F, 8to1:L, 8to6:L, 8to8:L, 8toe:L, 8tom:L, 5vt0:L, 7vwy:F, 7vwz:F, 7w5w:F, 7w5x:F, 7w5y:F, 6wmu:F, 6xh7:F, 6xh8:F, 6xl5:F, 6xl9:F, 6xlj:F, 6xll:F, 8y6u:F, 4yln:F, 4yln:L, 4yln:R, 4ylo:F, 4ylo:L, 4ylo:R, 4ylp:F, 4ylp:L, 4ylp:R
4 6psr:L 548 308 0.8555 0.5511 0.9805 0.0 6n58:L, 6n61:F
5 6psr:L 548 59 0.1416 0.0912 0.8475 4.33e-23 6n58:L, 6n61:F
6 4kn7:X 517 304 0.8187 0.5590 0.9507 0.0
7 4kn7:X 517 59 0.1416 0.0967 0.8475 4.36e-23
8 3iyd:F 479 314 0.7932 0.5846 0.8917 0.0
9 3iyd:F 479 59 0.1388 0.1023 0.8305 1.40e-22
10 8u3b:F 431 309 0.7195 0.5893 0.8220 1.38e-172
11 8u3b:F 431 65 0.1473 0.1206 0.8000 3.04e-23
12 7xya:F 302 305 0.5184 0.6060 0.6000 4.68e-127
13 6wmr:Z 470 316 0.3938 0.2957 0.4399 5.28e-74 6wmt:Z
14 6wmr:Z 470 61 0.1303 0.0979 0.7541 6.39e-20 6wmt:Z
15 7ye1:F 497 332 0.4136 0.2938 0.4398 5.41e-70 7ye2:F, 5yix:A
16 7ye1:F 497 61 0.1246 0.0885 0.7213 1.86e-18 7ye2:F, 5yix:A
17 6n60:F 318 103 0.2691 0.2987 0.9223 8.72e-61 8igr:L, 8igs:L
18 6n60:F 318 60 0.1530 0.1698 0.9000 4.84e-30 8igr:L, 8igs:L
19 6n60:F 318 59 0.1416 0.1572 0.8475 8.18e-24 8igr:L, 8igs:L
20 7ckq:F 272 123 0.1983 0.2574 0.5691 6.23e-39 7f75:F, 8x6f:E
21 7ckq:F 272 68 0.1105 0.1434 0.5735 2.94e-14 7f75:F, 8x6f:E
22 7ckq:F 272 41 0.0538 0.0699 0.4634 0.001 7f75:F, 8x6f:E
23 8k60:F 315 139 0.1955 0.2190 0.4964 1.58e-38 8dy7:F, 8dy9:F, 8hvr:F, 8jke:F, 7vpd:F, 7vpz:F, 7x74:F, 7x75:F, 7x76:F
24 8k60:F 315 64 0.0850 0.0952 0.4688 7.13e-10 8dy7:F, 8dy9:F, 8hvr:F, 8jke:F, 7vpd:F, 7vpz:F, 7x74:F, 7x75:F, 7x76:F
25 8k60:F 315 36 0.0510 0.0571 0.5000 1.61e-04 8dy7:F, 8dy9:F, 8hvr:F, 8jke:F, 7vpd:F, 7vpz:F, 7x74:F, 7x75:F, 7x76:F
26 7l7b:F 272 135 0.2040 0.2647 0.5333 4.58e-37
27 7l7b:F 272 46 0.0992 0.1287 0.7609 1.89e-13
28 7l7b:F 272 31 0.0397 0.0515 0.4516 0.008
29 6bzo:F 326 128 0.1870 0.2025 0.5156 6.71e-37 6c04:F, 6cce:F, 6ccv:F, 6dcf:F, 6edt:F, 6ee8:F, 6eec:F, 6fbv:F, 8hih:F, 7kif:F, 7kim:F, 7kin:F, 6m7j:F, 6ono:B, 6ono:D, 6onu:B, 6onu:D, 6onu:F, 6onu:H, 7p5x:AF, 5tw1:F, 7u22:F, 5uh5:F, 5uh6:F, 5uh8:F, 5uh9:F, 5uha:F, 5uhb:F, 5uhc:F, 5uhd:F, 5uhe:F, 5uhf:F, 5uhg:F, 5vi5:F, 5vi8:F, 6vvs:F, 6vvt:F, 6vvv:F, 6vvx:F, 6vvy:F, 6vvz:F, 6vw0:F
30 6bzo:F 326 55 0.0793 0.0859 0.5091 1.56e-09 6c04:F, 6cce:F, 6ccv:F, 6dcf:F, 6edt:F, 6ee8:F, 6eec:F, 6fbv:F, 8hih:F, 7kif:F, 7kim:F, 7kin:F, 6m7j:F, 6ono:B, 6ono:D, 6onu:B, 6onu:D, 6onu:F, 6onu:H, 7p5x:AF, 5tw1:F, 7u22:F, 5uh5:F, 5uh6:F, 5uh8:F, 5uh9:F, 5uha:F, 5uhb:F, 5uhc:F, 5uhd:F, 5uhe:F, 5uhf:F, 5uhg:F, 5vi5:F, 5vi8:F, 6vvs:F, 6vvt:F, 6vvv:F, 6vvx:F, 6vvy:F, 6vvz:F, 6vw0:F
31 6bzo:F 326 43 0.0510 0.0552 0.4186 0.003 6c04:F, 6cce:F, 6ccv:F, 6dcf:F, 6edt:F, 6ee8:F, 6eec:F, 6fbv:F, 8hih:F, 7kif:F, 7kim:F, 7kin:F, 6m7j:F, 6ono:B, 6ono:D, 6onu:B, 6onu:D, 6onu:F, 6onu:H, 7p5x:AF, 5tw1:F, 7u22:F, 5uh5:F, 5uh6:F, 5uh8:F, 5uh9:F, 5uha:F, 5uhb:F, 5uhc:F, 5uhd:F, 5uhe:F, 5uhf:F, 5uhg:F, 5vi5:F, 5vi8:F, 6vvs:F, 6vvt:F, 6vvv:F, 6vvx:F, 6vvy:F, 6vvz:F, 6vw0:F
32 8h3v:G 314 139 0.1955 0.2197 0.4964 1.36e-34 8h40:G
33 8h3v:G 314 53 0.0935 0.1051 0.6226 3.41e-12 8h40:G
34 8h3v:G 314 32 0.0368 0.0414 0.4062 0.32 8h40:G
35 7rdq:F 349 128 0.1898 0.1920 0.5234 3.43e-34 2a68:F, 2a68:P, 2a69:F, 2a69:P, 6cuu:F, 5d4c:F, 5d4c:P, 5d4d:F, 5d4d:P, 5d4e:F, 5d4e:P, 5e17:F, 5e18:F, 7eh0:F, 7eh1:F, 7eh2:F, 7eh2:P, 4g7h:F, 4g7h:P, 4g7o:F, 4g7o:P, 4g7z:F, 4g7z:P, 5i2d:F, 5i2d:Q, 1iw7:F, 1iw7:P, 4ki2:A, 4ki2:B, 6kqd:F, 6kqd:P, 6kqe:F, 6kqf:F, 6kqg:F, 6kqh:F, 6kql:F, 6kqm:F, 6kqn:F, 1ku7:A, 6l74:F, 6lts:F, 7mlb:F, 7mli:F, 7mlj:F, 3n97:A, 4oin:F, 4oio:F, 4oip:F, 4oiq:F, 4oir:F, 6ovr:F, 6ovy:F, 6ow3:F, 6oy5:F, 6oy6:F, 6oy7:F, 6p70:F, 6p71:F, 4q4z:F, 4q5s:F, 1rio:H, 1smy:F, 5tjg:F, 3ugo:A, 3ugp:A, 5vo8:F, 5voi:F, 8w8n:F, 8w8o:F, 8w8p:F, 6wox:F, 6woy:F, 5x21:F, 5x22:F, 5x22:P, 4xln:F, 4xln:L, 4xlp:F, 4xlp:L, 4xlq:F, 4xlq:L, 4xlr:F, 4xlr:L, 4xls:F, 4xls:L
36 7rdq:F 349 48 0.0850 0.0860 0.6250 5.01e-09 2a68:F, 2a68:P, 2a69:F, 2a69:P, 6cuu:F, 5d4c:F, 5d4c:P, 5d4d:F, 5d4d:P, 5d4e:F, 5d4e:P, 5e17:F, 5e18:F, 7eh0:F, 7eh1:F, 7eh2:F, 7eh2:P, 4g7h:F, 4g7h:P, 4g7o:F, 4g7o:P, 4g7z:F, 4g7z:P, 5i2d:F, 5i2d:Q, 1iw7:F, 1iw7:P, 4ki2:A, 4ki2:B, 6kqd:F, 6kqd:P, 6kqe:F, 6kqf:F, 6kqg:F, 6kqh:F, 6kql:F, 6kqm:F, 6kqn:F, 1ku7:A, 6l74:F, 6lts:F, 7mlb:F, 7mli:F, 7mlj:F, 3n97:A, 4oin:F, 4oio:F, 4oip:F, 4oiq:F, 4oir:F, 6ovr:F, 6ovy:F, 6ow3:F, 6oy5:F, 6oy6:F, 6oy7:F, 6p70:F, 6p71:F, 4q4z:F, 4q5s:F, 1rio:H, 1smy:F, 5tjg:F, 3ugo:A, 3ugp:A, 5vo8:F, 5voi:F, 8w8n:F, 8w8o:F, 8w8p:F, 6wox:F, 6woy:F, 5x21:F, 5x22:F, 5x22:P, 4xln:F, 4xln:L, 4xlp:F, 4xlp:L, 4xlq:F, 4xlq:L, 4xlr:F, 4xlr:L, 4xls:F, 4xls:L
37 7rdq:F 349 38 0.0482 0.0487 0.4474 0.96 2a68:F, 2a68:P, 2a69:F, 2a69:P, 6cuu:F, 5d4c:F, 5d4c:P, 5d4d:F, 5d4d:P, 5d4e:F, 5d4e:P, 5e17:F, 5e18:F, 7eh0:F, 7eh1:F, 7eh2:F, 7eh2:P, 4g7h:F, 4g7h:P, 4g7o:F, 4g7o:P, 4g7z:F, 4g7z:P, 5i2d:F, 5i2d:Q, 1iw7:F, 1iw7:P, 4ki2:A, 4ki2:B, 6kqd:F, 6kqd:P, 6kqe:F, 6kqf:F, 6kqg:F, 6kqh:F, 6kql:F, 6kqm:F, 6kqn:F, 1ku7:A, 6l74:F, 6lts:F, 7mlb:F, 7mli:F, 7mlj:F, 3n97:A, 4oin:F, 4oio:F, 4oip:F, 4oiq:F, 4oir:F, 6ovr:F, 6ovy:F, 6ow3:F, 6oy5:F, 6oy6:F, 6oy7:F, 6p70:F, 6p71:F, 4q4z:F, 4q5s:F, 1rio:H, 1smy:F, 5tjg:F, 3ugo:A, 3ugp:A, 5vo8:F, 5voi:F, 8w8n:F, 8w8o:F, 8w8p:F, 6wox:F, 6woy:F, 5x21:F, 5x22:F, 5x22:P, 4xln:F, 4xln:L, 4xlp:F, 4xlp:L, 4xlq:F, 4xlq:L, 4xlr:F, 4xlr:L, 4xls:F, 4xls:L
38 8gzg:F 314 128 0.1813 0.2038 0.5000 7.09e-33 8gzh:F
39 8gzg:F 314 54 0.0935 0.1051 0.6111 3.22e-12 8gzh:F
40 8gzg:F 314 32 0.0397 0.0446 0.4375 0.23 8gzh:F
41 7f0r:F 278 113 0.1615 0.2050 0.5044 2.49e-28
42 7f0r:F 278 50 0.0623 0.0791 0.4400 1.29e-05
43 6omf:F 278 94 0.1473 0.1871 0.5532 1.38e-27 5ipl:F, 5ipm:F, 5ipn:F, 6kj6:F, 6utv:FFF, 6utw:FFF, 6utx:FFF, 6uty:FFF, 6utz:FFF, 6uu0:FFF, 6uu1:FFF, 6uu2:FFF, 6uu3:FFF, 6uu4:FFF, 6uu5:FFF, 6uu6:FFF, 6uu7:FFF, 6uu8:FFF, 6uu9:FFF, 6uua:FFF, 6uub:FFF, 6uuc:FFF
44 6omf:F 278 48 0.0623 0.0791 0.4583 3.87e-05 5ipl:F, 5ipm:F, 5ipn:F, 6kj6:F, 6utv:FFF, 6utw:FFF, 6utx:FFF, 6uty:FFF, 6utz:FFF, 6uu0:FFF, 6uu1:FFF, 6uu2:FFF, 6uu3:FFF, 6uu4:FFF, 6uu5:FFF, 6uu6:FFF, 6uu7:FFF, 6uu8:FFF, 6uu9:FFF, 6uua:FFF, 6uub:FFF, 6uuc:FFF
45 8hkc:E 262 128 0.1246 0.1679 0.3438 9.46e-12
46 8hkc:E 262 46 0.0482 0.0649 0.3696 0.019
47 8cwr:B 109 55 0.0793 0.2569 0.5091 5.99e-10 8cwt:B, 8cwt:D, 8cwt:F, 8cyf:B, 7kuf:B
48 6ido:A 86 48 0.0623 0.2558 0.4583 2.46e-06 6ido:B
49 6pmi:F 239 37 0.0482 0.0711 0.4595 0.001 6pmj:F
50 8x6g:H 244 78 0.0623 0.0902 0.2821 0.009
51 6pfv:G 223 37 0.0453 0.0717 0.4324 0.011 6pfj:A, 6pfv:A, 6pfv:D
52 6ttb:A 331 148 0.0935 0.0997 0.2230 0.091
53 2dqu:H 222 95 0.0737 0.1171 0.2737 1.5 2dqt:H, 3ls4:H, 4p3c:H, 4p3d:A, 4p3d:H, 4qxu:H
54 3h0d:A 155 23 0.0283 0.0645 0.4348 2.2 3h0d:B
55 1ez4:B 318 96 0.0567 0.0629 0.2083 2.6 1ez4:A, 1ez4:C, 1ez4:D
56 7vdv:A 809 106 0.0935 0.0408 0.3113 2.9 7vdt:A
57 5or5:A 95 54 0.0538 0.2000 0.3519 3.5
58 6uel:A 1333 48 0.0453 0.0120 0.3333 7.1 6uel:B
59 6w2j:B 1364 48 0.0453 0.0117 0.3333 7.1
60 5dou:D 1430 48 0.0453 0.0112 0.3333 7.2 5dou:A, 5dou:B, 5dou:C, 6w2j:A
61 6db6:H 226 20 0.0283 0.0442 0.5000 8.1
62 7lq4:A 192 156 0.1190 0.2188 0.2692 8.3
63 7phw:E 226 21 0.0255 0.0398 0.4286 8.6 7phw:B, 7pi3:F, 7pi3:M, 7pi3:T, 7pi3:a
64 7aoi:BL 234 90 0.0595 0.0897 0.2333 8.8 6hiv:BL, 6hix:BL
65 5fgc:E 225 47 0.0425 0.0667 0.3191 9.5

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218