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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
EIEVTGWEQALKWLRSNTSKYATATSWWDYGYWIESSLLGNRRRDRDHILALFLARDGNISEVDFESWELNYFIIYLNDW
AKFNAISYLGGAITRKEYNGDENGRGRVTTILLTQAAGNVYVNPYARIVIKVIQQNKTRRIAVNIGQLECSPILSVAFPG
NIKIKGSGRCSDGSPFPYVVYLTPSLGVLAYYKVATSNFVKLAFGIPTSSYSEFAEKLFSNFIPVYQYGSVIVYEFRPFA
IYKIEDFINGTWREVGKLSPGKHTLRLYISAFGRDIKNATLYVYALNGTKIIKRIKVGEIKYMNHLEEYPIIVNVTLPTA
QKYRFILAQKGPVGVLTGPVRVNGKITNPAYIMREGESGRLELKVGVDKEYTADLYLRATFIYLVRKGGKSNEDYDASFE
PHMDTFFITKLKEGIKLRPGENEIVVNAEMPKNAISSYKEKLEKEHGDKLIIRGIRVEPVFIVEKEYTMIEVSASAPHHH
HHHHHHHH

The query sequence (length=488) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3vu1:B 490 487 0.9816 0.9776 0.9836 0.0 3vu1:A
2 3wov:A 457 473 0.7070 0.7549 0.7294 0.0
3 5aza:A 836 469 0.6270 0.3660 0.6525 0.0 5b3z:A, 5b3z:B, 5b3z:C, 5b3z:D, 2zag:A, 2zag:B, 2zag:C, 2zag:D, 2zai:A, 2zai:B, 2zai:C, 2zai:D
4 6s7t:A 706 47 0.0389 0.0269 0.4043 0.003
5 6s7o:A 656 36 0.0348 0.0259 0.4722 0.024 6ftg:5, 6fti:5, 6ftj:5, 8pn9:A
6 6ezn:F 650 51 0.0328 0.0246 0.3137 0.15 8agb:A, 8age:A, 6c26:A, 7oci:F
7 8agc:A 697 51 0.0328 0.0230 0.3137 0.16
8 3waj:A 793 57 0.0369 0.0227 0.3158 2.3
9 7e9s:A 867 57 0.0369 0.0208 0.3158 2.4 5gmy:A, 3wak:A
10 1cxa:A 124 56 0.0348 0.1371 0.3036 2.7 1cxc:A, 2cxb:A, 2cxb:B, 1l9b:C, 1l9j:C, 1l9j:D
11 2c3c:A 522 175 0.0922 0.0862 0.2571 2.9 2c3c:B, 2c3d:A, 2c3d:B, 7mgn:A, 7mgn:B, 7mgo:B, 1mo9:A, 1mo9:B, 1mok:A, 1mok:B, 1mok:C, 1mok:D, 3q6j:A, 3q6j:B
12 2xgj:B 777 23 0.0246 0.0154 0.5217 2.9
13 6fsz:MM 978 23 0.0246 0.0123 0.5217 3.4 7ajt:EN, 7aju:EN, 6ft6:MM, 5ooq:A, 5ooq:B, 2xgj:A
14 8wiv:D 602 117 0.0635 0.0515 0.2650 3.7 8wk0:D
15 8wiv:O 657 117 0.0635 0.0472 0.2650 4.2 8wiv:M, 8wiv:L, 8wj3:M, 8wj3:O, 8wj3:L, 8wk0:M, 8wk0:O, 8wk0:L
16 8fru:Z 134 133 0.0738 0.2687 0.2707 5.5 8brm:La, 8bsi:La, 8bsj:La, 8btd:La, 8btr:La, 7pwg:Z, 7pwo:Z2
17 4g97:A 243 73 0.0451 0.0905 0.3014 7.8
18 7tbu:A 450 115 0.0553 0.0600 0.2348 9.4 7tbu:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218