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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
EHVILLNAQGVPTGTLEKYAAHTADTRLHLAFSSWLFNAKGQLLVTRRALSKKAWPGVWTNSVCGHPQLGESNEDAVIRR
CRYELGVEITPPESIYPDFRFRATDPSGIVENEVCPVFAARTTSALQINDDEVMDYQWCDLADVLHGIDATPWAFSPWMV
MQATNREARKRLSAFT

The query sequence (length=176) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2b2k:B 180 176 1.0000 0.9778 1.0000 2.08e-133 2b2k:A, 2g73:A, 2g73:B, 2g74:A, 2g74:B, 1hx3:A, 1hx3:B, 1i9a:A, 1i9a:B, 1nfs:A, 1nfs:B, 1nfz:A, 1nfz:B, 1ow2:A, 1ow2:B, 1ppv:A, 1ppv:B, 1ppw:A, 1ppw:B, 1pvf:A, 1pvf:B, 1q54:A, 1q54:B, 1r67:A, 2vnp:A, 2vnp:B, 2vnq:A, 2vnq:B, 1x83:A, 1x83:B, 1x84:A, 1x84:B
2 2i6k:A 224 153 0.2614 0.2054 0.3007 1.02e-11 2dho:A, 2i6k:B, 2icj:A, 2ick:A
3 2pny:A 233 115 0.2045 0.1545 0.3130 8.81e-08
4 1vc8:A 126 87 0.1705 0.2381 0.3448 6.70e-04 1vc8:B, 1vc9:A, 1vc9:B
5 5zrk:A 129 63 0.1193 0.1628 0.3333 0.26 5zrg:A, 5zrh:A, 5zri:A, 5zrk:B, 5zrl:A, 5zrl:B, 5zro:A, 5zro:B
6 7ohy:b 375 69 0.1136 0.0533 0.2899 0.32
7 2e50:P 186 84 0.1364 0.1290 0.2857 0.40 2e50:A, 2e50:Q
8 1e1c:A 727 52 0.0966 0.0234 0.3269 0.46 1e1c:C, 1req:A, 1req:C, 2req:A, 2req:C, 3req:A, 4req:A, 4req:C, 5req:A, 5req:C, 6req:A, 6req:C, 7req:A, 7req:C
9 6scx:A 328 107 0.1420 0.0762 0.2336 0.50 6o3p:A, 6scx:B, 6scx:C
10 7mto:A 188 84 0.1364 0.1277 0.2857 0.53 2e50:B
11 1ppx:A 129 74 0.1250 0.1705 0.2973 0.76 3a6t:A, 3a6u:A, 3a6v:A, 3a6v:B, 1pun:A, 1puq:A, 1pus:A, 1tum:A, 7ww5:A, 7ww6:A, 7ww7:A, 7ww8:A, 7ww9:A, 7wwa:A, 7x9h:A, 7x9i:A, 7x9j:A, 7x9k:A, 7x9l:A, 7x9n:A, 7x9o:A
12 6o3p:B 320 88 0.1136 0.0625 0.2273 1.4
13 6ylg:b 613 66 0.1080 0.0310 0.2879 2.4 7nac:b, 7of1:b, 7r7a:b, 6ylh:b
14 8hfr:rA 647 66 0.1080 0.0294 0.2879 2.6 7bt6:b, 7btb:b, 6c0f:W, 6ft6:b, 3jct:b, 5jcs:o, 6m62:b, 6n8j:b, 6n8k:b, 7nad:b, 7oh3:b, 7ohq:b, 7oht:b, 7r72:b, 7u0h:b, 7ug6:b, 7uoo:b, 7uqb:b, 7uqz:b, 7v08:b, 4v7f:o, 8v87:b, 6ylx:b, 6yly:b, 7z34:b
15 8v83:b 423 66 0.1080 0.0449 0.2879 2.6 6elz:b, 6em1:b, 6em5:b, 7ohp:b, 7ohr:b, 7ohs:b, 7ohu:b, 7ohv:b, 8v84:b
16 3hhj:B 131 62 0.1023 0.1374 0.2903 3.2 3hhj:A
17 3i1l:A 362 51 0.0795 0.0387 0.2745 4.2 3i1l:B, 3i1l:C
18 3r03:A 131 59 0.1023 0.1374 0.3051 4.4
19 3kzp:B 232 34 0.0739 0.0560 0.3824 5.4 3kzp:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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