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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
EGLSIFVILVWLGLNVFLFVWYYRVYDIPPKFFYTRKLLGSALALARAPAACLNFNCMLILLPVCRNLLSFLRGSSTRVR
RQLDRNLTFHKMVAWMIALHSAIHTIAHLFNVEWCVNARVNNSDPYSVALSELGDRQNESYLNFARKRIKNPEGGLYLAV
TLLAGITGVVITLCLILIITSSTKTIRRSYFEVFWYTHHLFVIFFIGLAIHGAERIVRGQTAESLAVHNITVCEQKISEW
GKIKECPIPQFAGNPPMTWKWIVGPMFLYLCERLVRFWRSQQKVVITKVVTHPFKTIELQMKKKGFKMEVGQYIFVKCPK
VSKLEWHPFTLTSAPEEDFFSIHIRIVGDWTEGLFNACGCDKLPKIAVDGPFGTASEDVFSYEVVMLVGAGIGVTPFASI
LKSVWYKYCNNATNLKLKKIYFYWLCRDTHAFEWFADLLQLLESQMQERNNAGFLSYNIYLTGQKTLYGRPNWDNEFKTI
ASQHPNTRIGVFLCGPEALAETLSKQSISNSESGPRGVHFIFNKE

The query sequence (length=525) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8x2l:B 525 525 1.0000 1.0000 1.0000 0.0 7u8g:A
2 8wej:B 569 561 1.0000 0.9227 0.9358 0.0 8gz3:B, 8kei:B
3 6wxv:A 1091 484 0.2686 0.1292 0.2913 4.79e-58 6wxr:A, 6wxu:C, 6wxu:A
4 7d3e:C 1380 498 0.2724 0.1036 0.2871 1.07e-55 7d3e:A, 7d3f:C, 7d3f:A
5 5o0x:A 261 231 0.1867 0.3755 0.4242 1.06e-54 8cak:A, 8cal:A, 8cao:A, 8cap:A, 8cap:E, 8cap:B, 8cap:C, 8cb0:A
6 8u87:A 621 555 0.2914 0.2464 0.2757 1.47e-53 8u7y:A, 8u7y:B, 8u85:A, 8u85:C, 8u86:A, 8u86:C, 8u87:C
7 5o0t:A 206 169 0.0819 0.2087 0.2544 3.08e-09
8 5ksw:B 262 102 0.0552 0.1107 0.2843 6.09e-06 5ksw:D, 5ue9:B, 5ue9:D
9 4ylf:A 276 135 0.0724 0.1377 0.2815 9.81e-05 4ylf:C, 4yry:A, 4yry:C
10 8qq7:A 399 225 0.0933 0.1228 0.2178 3.17e-04 8qq1:C, 8qq1:F, 8qq1:G, 8qq5:A, 8qq5:B, 8qq5:C, 8qt6:A, 8qt7:A, 8qt9:A, 8qta:A
11 5ogx:A 333 220 0.0971 0.1532 0.2318 0.011
12 1krh:A 337 111 0.0533 0.0831 0.2523 0.12 1krh:B
13 1cqx:A 403 101 0.0438 0.0571 0.2277 0.20 1cqx:B, 3ozu:A, 3ozv:B, 3ozv:A, 3ozw:A, 3ozw:B
14 4b4d:A 256 106 0.0552 0.1133 0.2736 0.63
15 7bbv:A 298 135 0.0552 0.0973 0.2148 0.71 7bbv:B
16 5i4m:A 414 65 0.0362 0.0459 0.2923 0.98 5i4m:B, 5thw:A, 5thw:B, 5thw:C, 5thw:D
17 8gpm:A 193 59 0.0324 0.0881 0.2881 2.1 8gpp:A, 8gpp:B, 8gpp:C
18 4r3u:A 557 107 0.0571 0.0539 0.2804 2.4 4r3u:B
19 1gvh:A 396 220 0.0895 0.1187 0.2136 4.2
20 2eix:A 243 100 0.0419 0.0905 0.2200 4.5 2eix:B
21 3u5m:E 173 38 0.0305 0.0925 0.4211 4.7
22 6rr3:A 257 107 0.0552 0.1128 0.2710 6.1 6rra:A
23 3bg6:A 577 73 0.0381 0.0347 0.2740 7.4 3bg6:B, 3bg6:C, 3bg6:D, 3bg6:E, 3bg6:F, 3bg6:G, 3bg6:H, 3bg7:A, 3bg7:B, 3bg7:C, 3bg7:D, 3bg7:E, 3bg7:F, 3bg7:G, 3bg7:H, 3bly:A, 2f5v:A, 2f6c:A, 3fdy:A, 2igk:A, 2igk:B, 2igk:C, 2igk:D, 2igk:E, 2igk:F, 2igk:G, 2igk:H, 2igm:A, 2igm:B, 2igm:D, 2igm:C, 2igm:E, 2igm:F, 2igm:G, 2igm:H, 2ign:A, 2ign:B, 2ign:D, 2ign:C, 2ign:E, 2ign:F, 2ign:H, 2ign:G, 2igo:A, 2igo:B, 2igo:D, 2igo:C, 2igo:E, 2igo:F, 2igo:H, 2igo:G, 3k4b:A, 3k4c:A, 3k4c:B, 3k4c:C, 3k4c:D, 3k4j:A, 3k4k:A, 3k4l:A, 3k4l:B, 3k4m:A, 3k4m:B, 3k4m:C, 3k4m:D, 3k4m:E, 3k4m:F, 3k4m:G, 3k4m:H, 3k4n:A, 3k4n:B, 3lsh:A, 3lsh:B, 3lsh:C, 3lsh:D, 3lsi:A, 3lsi:B, 3lsk:A, 3lsk:B, 3lsk:C, 3lsk:D, 3lsm:A, 3lsm:B, 4moe:A, 4moe:B, 4moe:C, 4moe:D, 4mof:A, 4mog:A, 4moh:A, 4moi:A, 4moi:B, 4moj:A, 4moj:B, 4moj:C, 4moj:D, 4mok:A, 4mok:B, 4mok:C, 4mok:D, 4mol:A, 4mol:B, 4mol:C, 4mol:D, 4mom:A, 4mom:B, 4mom:C, 4mom:D, 4moo:A, 4mop:A, 4mop:B, 4mop:C, 4mop:D, 4moq:A, 4moq:B, 4mor:A, 4mor:B, 4mor:C, 4mor:D, 4mos:A, 3pl8:A, 1tt0:A, 1tt0:B, 1tt0:C, 1tt0:D, 1tzl:A, 1tzl:B, 1tzl:C, 1tzl:D, 1tzl:E, 1tzl:F, 1tzl:G, 1tzl:H

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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