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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
EFSMEDLIPLVNRLQDAFSADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLVLQLVNATTEYAEFLHCK
GKKFTDFEEVRLEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKE
NCLILAVSPANSDLANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIDGKKD
ITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKLQSQLLSIEKEVEEYKNFSRVDEMLRMY
HALKEALSIIGNI

The query sequence (length=333) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6dlu:P 747 325 0.9369 0.4177 0.9600 0.0 2aka:B, 5d3q:A, 5d3q:B, 6dlu:B, 6s9a:B, 2x2e:A, 2x2e:D, 2x2f:A, 2x2f:D, 3zyc:A, 3zyc:D
2 6dlu:P 747 29 0.0631 0.0281 0.7241 8.23e-05 2aka:B, 5d3q:A, 5d3q:B, 6dlu:B, 6s9a:B, 2x2e:A, 2x2e:D, 2x2f:A, 2x2f:D, 3zyc:A, 3zyc:D
3 8sxz:c 699 325 0.9339 0.4449 0.9569 0.0 8sxz:b, 8sxz:f, 8sxz:g, 8sz8:b, 8sz8:c, 8sz8:f, 8sz8:g, 8t0k:b, 8t0k:c, 8t0k:f, 8t0k:g, 8t0r:b, 8t0r:c, 8t0r:f, 8t0r:g, 8tym:c, 8tym:f, 8tym:B, 8tym:C, 8tyn:c, 8tyn:f, 8tyn:C, 8tyn:F
4 8sxz:c 699 29 0.0661 0.0315 0.7586 2.16e-05 8sxz:b, 8sxz:f, 8sxz:g, 8sz8:b, 8sz8:c, 8sz8:f, 8sz8:g, 8t0k:b, 8t0k:c, 8t0k:f, 8t0k:g, 8t0r:b, 8t0r:c, 8t0r:f, 8t0r:g, 8tym:c, 8tym:f, 8tym:B, 8tym:C, 8tyn:c, 8tyn:f, 8tyn:C, 8tyn:F
5 7ax3:D2 582 321 0.9249 0.5292 0.9595 0.0 7ax3:B2, 7ax3:B, 7ax3:D, 7ax3:F, 7ax3:H, 7ax3:J, 7ax3:M, 7ax3:O, 7ax3:Q, 7ax3:S, 7ax3:U, 7ax3:W, 7ax3:Y, 7ax3:E2, 7ax3:G2, 7ax3:H2, 7ax3:I2, 7ax3:J2
6 7ax3:D2 582 29 0.0661 0.0378 0.7586 1.73e-05 7ax3:B2, 7ax3:B, 7ax3:D, 7ax3:F, 7ax3:H, 7ax3:J, 7ax3:M, 7ax3:O, 7ax3:Q, 7ax3:S, 7ax3:U, 7ax3:W, 7ax3:Y, 7ax3:E2, 7ax3:G2, 7ax3:H2, 7ax3:I2, 7ax3:J2
7 6s9a:A 312 334 0.8919 0.9519 0.8892 0.0
8 3l43:B 246 255 0.6607 0.8943 0.8627 1.99e-163 3l43:A, 3l43:C, 3l43:D
9 6djq:B 330 330 0.5856 0.5909 0.5909 3.39e-134
10 6def:C 368 362 0.5916 0.5353 0.5442 7.87e-133 6def:A, 6def:B, 6def:D, 6di7:A, 6djq:A, 6djq:C, 6djq:D, 6vjf:A, 6vjf:B, 6vjf:C, 6vjf:D
11 4h1v:A 358 357 0.5646 0.5251 0.5266 8.85e-123
12 5wp9:A 590 297 0.5225 0.2949 0.5859 4.39e-120 8skn:A, 8skn:B, 3w6n:A, 3w6n:B, 3w6o:A, 3w6o:B, 3w6p:A, 3w6p:B, 5wp9:C, 5wp9:E, 5wp9:G, 5wp9:I, 5wp9:K, 5wp9:M, 5wp9:O
13 3t34:B 341 343 0.5255 0.5132 0.5102 2.08e-114 3t34:A, 3t35:A, 3t35:B, 3t35:C, 3t35:D
14 1jwy:A 1039 308 0.5105 0.1636 0.5519 9.71e-99 4ae3:A, 2aka:A, 7b19:A, 7b1a:A, 3bz7:A, 3bz8:A, 3bz9:A, 1d0x:A, 1d0y:A, 1d0z:A, 1d1a:A, 1d1b:A, 1d1c:A, 1fmw:A, 2jhr:A, 2jj9:A, 1jx2:A, 1lvk:A, 3mjx:A, 3mkd:A, 1mma:A, 1mmd:A, 1mmg:A, 1mmn:A, 1mne:A, 3mnq:A, 3myh:X, 3myk:X, 3myl:X, 4pjk:A, 1vom:A, 1w9i:A, 1w9j:A, 1w9k:A, 1w9l:A, 2x9h:A, 2xel:A, 2xo8:A, 2y8i:X, 1yv3:A, 6z2s:A, 6z7t:A, 6z7t:B, 6z7u:A
15 4p4s:B 336 299 0.3694 0.3661 0.4114 4.63e-66 4p4s:A, 4p4t:A
16 6jsj:A 625 249 0.3183 0.1696 0.4257 1.86e-45 6jsj:B, 6jsj:C
17 8eew:A 766 245 0.2222 0.0966 0.3020 4.66e-25 8eew:B, 8eff:A, 8eff:B, 8eff:C, 8eff:D, 8efr:A, 8efr:B, 8efr:C, 8efr:K, 8efr:D, 8efr:L, 8efr:E, 8efr:M, 8efr:F, 8efr:N, 8efr:G, 8efr:O, 8efr:H, 8efr:P, 8efr:I, 8efr:Q, 8efr:J, 8efr:R, 6jtg:A
18 5oxf:C 601 132 0.1321 0.0732 0.3333 0.008 5oxf:D
19 6vmb:B 503 54 0.0511 0.0338 0.3148 3.2 6fkf:A, 6fkf:C, 6fkf:E, 6fkh:C, 6fkh:E, 6fkh:A, 6fki:E, 6fki:A, 6fki:C, 1kmh:A, 6vmb:A, 6vmb:C, 6vmd:A, 6vmd:B, 6vmd:C, 6vof:A, 6vof:B, 6vof:C, 6vog:A, 6vog:B, 6vog:C, 6voh:A, 6voh:C, 6voh:B, 6voi:A, 6voi:C, 6voi:B, 6voj:A, 6voj:B, 6voj:C, 6vok:A, 6vok:B, 6vok:C, 6vol:A, 6vol:B, 6vol:C, 6vom:A, 6vom:B, 6vom:C, 6von:A, 6von:B, 6von:C, 6voo:A, 6voo:B, 6voo:C
20 1svw:A 190 31 0.0390 0.0684 0.4194 3.4 1svi:A, 1svw:B
21 7nyx:A 1467 50 0.0541 0.0123 0.3600 4.1 7nyx:B, 7nyz:A, 7nyz:B, 7nz0:B, 7nz0:A, 7nz2:A3, 7nz2:B3, 7nz2:A4, 7nz2:B4, 7nz2:A1, 7nz2:B1, 7nz2:A2, 7nz2:B2, 7nz3:A1, 7nz3:B1, 7nz3:A2, 7nz3:B2
22 1ggz:A 144 63 0.0511 0.1181 0.2698 4.5
23 4gki:A 272 116 0.0931 0.1140 0.2672 4.5 4ej7:A, 4ej7:B, 4ej7:C, 4feu:A, 4feu:B, 4feu:C, 4feu:D, 4feu:E, 4feu:F, 4fev:A, 4fev:B, 4fev:C, 4fev:D, 4fev:E, 4fev:F, 4few:A, 4few:B, 4few:C, 4few:D, 4few:E, 4few:F, 4fex:A, 4fex:B, 4fex:C, 4fex:D, 4fex:E, 4gkh:A, 4gkh:B, 4gkh:C, 4gkh:D, 4gkh:E, 4gkh:F, 4gkh:G, 4gkh:H, 4gkh:I, 4gkh:J, 4gkh:K, 4gkh:L, 4gki:B, 4gki:C, 4gki:D, 4gki:E, 4gki:F, 4gki:G, 4gki:H, 4gki:I, 4gki:J, 4gki:K, 4gki:L
24 8kab:h 430 54 0.0541 0.0419 0.3333 4.8
25 5gom:A 407 48 0.0450 0.0369 0.3125 5.0 5gnr:A, 5gof:A, 5gom:B, 5yew:A, 5yew:B, 5yew:C
26 5goe:A 384 33 0.0390 0.0339 0.3939 5.2 5gns:A, 5gnt:A
27 7ezi:A 323 51 0.0390 0.0402 0.2549 7.4 7ezl:A
28 4y0a:A 179 30 0.0420 0.0782 0.4667 8.7
29 5oxf:B 591 42 0.0511 0.0288 0.4048 9.6
30 8qby:E 236 28 0.0300 0.0424 0.3571 9.8

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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