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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
EFSIIDQYFNRQSHPDVALGIGDDSALITPPPNQQLVICADTLVAGRHFPLETSPHAIGWKSVAVNLSDIAAMGAKPHSI
LLAISLPQVDHEWLEGFSQGIYDCCNQFGVALIGGDTTQGPHLTITVTAMGWIETGKAVLRSGAKVGDYVCVSGQIGDAA
YGLQHLGHSLQQRLDYPTPRCKLGEELKGLASSMIDVSDGLAQDLGHILKASKVGARLILEKLPVDPVLQQIEEQQRWQY
ALAGGDDYELCFTITPQNYEKLLQKQLDVKITMIGQIVEQTKLTFEHLGSDYPLQI

The query sequence (length=296) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5cm7:A 305 296 1.0000 0.9705 1.0000 0.0 5cc8:A, 5cc8:B, 5cm7:B, 5dd7:A, 5dd7:B, 6mfm:A, 6mfm:B
2 7du3:B 327 274 0.3851 0.3486 0.4161 2.70e-62 7du3:A, 8yku:A
3 3c9u:B 312 273 0.3007 0.2853 0.3260 3.86e-37 3c9r:A, 3c9r:B, 3c9s:A, 3c9s:B, 3c9t:A, 3c9t:B, 3c9u:A
4 3vti:C 305 183 0.1791 0.1738 0.2896 2.83e-08 3vti:D
5 2yye:B 343 313 0.2500 0.2157 0.2364 3.09e-08 2yye:A, 2zau:A, 2zau:C
6 3m84:A 348 131 0.1081 0.0920 0.2443 4.84e-06 3qty:A, 3qty:B
7 3vyt:C 336 191 0.1588 0.1399 0.2461 9.96e-06 3vys:C, 3wjp:A, 3wjq:A, 3wjr:A
8 2z1u:A 335 185 0.1588 0.1403 0.2541 1.66e-04
9 5vk4:B 330 180 0.1520 0.1364 0.2500 1.72e-04 5vk4:A
10 3u0o:B 335 204 0.1689 0.1493 0.2451 3.93e-04 3u0o:A
11 3p4e:A 323 207 0.1824 0.1672 0.2609 7.65e-04
12 1cli:A 341 123 0.1081 0.0938 0.2602 0.002 1cli:B, 1cli:C, 1cli:D
13 3fd5:B 355 135 0.1081 0.0901 0.2370 0.010 3fd5:A, 3fd6:A, 3fd6:B
14 2hs3:A 602 223 0.1520 0.0748 0.2018 0.018 3d54:A, 3d54:E, 3d54:I, 2hs4:A
15 2hru:A 581 92 0.0743 0.0379 0.2391 0.026 2hry:A, 2hs0:A
16 4mri:B 303 122 0.1081 0.1056 0.2623 0.090 2i3c:A, 2i3c:B, 4mri:A, 4mxu:A, 4mxu:B, 4nfr:A, 4nfr:B, 2o4h:A, 2o4h:B, 2o53:A, 2o53:B, 2q51:A, 2q51:B, 4tnu:A, 4tnu:B
17 3viu:A 703 54 0.0676 0.0284 0.3704 1.8
18 8k5p:M 744 104 0.1047 0.0417 0.2981 2.0
19 7tnb:AAA 353 76 0.0709 0.0595 0.2763 2.2
20 8jch:M 721 104 0.1047 0.0430 0.2981 2.2
21 2gu2:A 307 121 0.0980 0.0945 0.2397 2.9 2gu2:B, 2q4z:B
22 6nfp:A 292 94 0.0946 0.0959 0.2979 3.1 6dkt:A, 6dkt:B, 6dkt:C, 6dkt:D, 6dkt:F, 6nfp:B, 6nfp:C, 6nfp:D, 6nfp:E, 6nfp:F
23 4avn:A 420 36 0.0439 0.0310 0.3611 3.2 4avo:A, 4b4f:A, 4b4f:B
24 1vf1:A 226 66 0.0709 0.0929 0.3182 6.4 1vf2:A, 1vf2:B, 1vf3:A, 1vf3:B
25 7c5x:A 506 100 0.0845 0.0494 0.2500 9.6 7c5x:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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