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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
EFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNL
GTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSR
NRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGL
MTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATC
LNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDKGEMCSGHGQCSCGDCLCDS
DWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDREPYMTENTC
NRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKG

The query sequence (length=539) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1u8c:B 599 548 1.0000 0.8998 0.9836 0.0 1jv2:B, 1l5g:B, 1m1x:B
2 8t2v:B 718 638 0.9388 0.7047 0.7931 0.0 4cak:B, 3fcs:B, 3fcs:D, 3fcu:B, 3fcu:D, 3fcu:F, 4g1e:B, 4g1m:B, 8gcd:B, 8gce:B, 5hdb:B, 5hdb:D, 3ije:B, 7l8p:B, 7l8p:D, 7la4:B, 6mk0:B, 4mmx:B, 4mmy:B, 4mmz:B, 6msl:B, 6msu:B, 6naj:B, 3nid:B, 3nid:D, 3nif:B, 3nif:D, 3nig:B, 3nig:D, 4o02:B, 8t2u:B, 3t3m:B, 3t3m:D, 3t3p:B, 3t3p:D, 7tct:B, 7tct:D, 7td8:B, 7td8:D, 7tho:B, 7tho:D, 7tmz:B, 7tmz:D, 7tpd:B, 7tpd:D, 1tye:B, 1tye:D, 1tye:F, 7u60:B, 7u60:D, 7u9f:B, 7u9f:D, 7u9v:B, 7u9v:D, 7ubr:B, 7ubr:D, 7ucy:B, 7ucy:D, 7udg:B, 7udg:D, 7udh:B, 7udh:D, 7ue0:B, 7ue0:D, 7ufh:B, 7ufh:D, 7uh8:B, 7uh8:D, 7uje:B, 7uje:D, 7ujk:B, 7ujk:D, 7uk9:B, 7uk9:D, 7uko:B, 7uko:D, 7ukp:B, 7ukp:D, 7ukt:B, 7ukt:D, 6v4p:B, 2vc2:B, 2vdk:B, 2vdl:B, 2vdm:B, 2vdn:B, 2vdo:B, 2vdp:B, 2vdq:B, 2vdr:B, 4z7n:B, 4z7n:D, 4z7o:B, 4z7o:D, 4z7q:B, 4z7q:D, 3zdx:B, 3zdx:D, 3zdy:B, 3zdy:D, 3zdz:B, 3zdz:D, 3ze0:B, 3ze0:D, 3ze1:B, 3ze1:D, 3ze2:B, 3ze2:D
3 6bxj:A 619 638 0.5826 0.5073 0.4922 2.14e-166 3bn3:A, 3bqm:B, 3bqm:C, 3bqn:B, 3bqn:C, 6bxb:A, 6bxb:B, 6bxf:A, 6bxf:B, 6ckb:A, 6ckb:B, 1cqp:A, 1cqp:B, 3e2m:A, 3e2m:B, 3eob:I, 3eob:J, 3f74:C, 3f78:A, 3f78:B, 3f78:C, 3hi6:A, 3hi6:B, 2ica:A, 4ixd:A, 7kc3:C, 7kc5:A, 7kc5:C, 7kc6:C, 7kc6:A, 1lfa:A, 1lfa:B, 3m6f:A, 1mjn:A, 1mq8:B, 1mq8:D, 1mq9:A, 2o7n:A, 1rd4:A, 1rd4:B, 1rd4:C, 1rd4:D, 1t0p:A, 3tcx:B, 3tcx:D, 3tcx:F, 3tcx:H, 3tcx:J, 3tcx:L, 3tcx:N, 3tcx:P, 3tcx:R, 3tcx:T, 3tcx:V, 3tcx:X, 3tcx:Z, 3tcx:b, 1xdd:A, 1xdd:B, 1xdg:A, 1xdg:B, 1xuo:A, 1xuo:B, 1zoo:A, 1zoo:B, 1zop:A, 1zop:B
4 4um9:D 455 407 0.3896 0.4615 0.5160 5.65e-146 5ffg:B, 5ffo:B, 5ffo:F, 5neu:B, 8tcg:B, 4um8:B, 4um8:D, 4um9:B
5 7nxd:B 690 637 0.4249 0.3319 0.3595 3.13e-118 7ceb:B, 7cec:B, 9ckv:B, 7nwl:B, 3vi3:B, 3vi3:D, 3vi4:D, 3vi4:B, 4wjk:B, 4wk0:B, 4wk2:B, 4wk4:B
6 8zjf:B 510 453 0.3599 0.3804 0.4283 4.96e-117 3v4p:B, 3v4p:D, 3v4v:B, 3v4v:D
7 5es4:B 674 469 0.3581 0.2864 0.4115 4.46e-111 5e6r:B, 5e6s:B, 5e6s:D, 5e6s:F, 5e6u:B, 5es4:D, 5es4:F, 5es4:H, 3k6s:B, 3k6s:D, 3k6s:F, 3k6s:H, 3k71:B, 3k71:D, 3k71:F, 3k71:H, 3k72:B, 3k72:D, 4neh:B, 4nen:B, 7usl:B, 7usm:B
8 5es4:B 674 166 0.0928 0.0742 0.3012 8.25e-15 5e6r:B, 5e6s:B, 5e6s:D, 5e6s:F, 5e6u:B, 5es4:D, 5es4:F, 5es4:H, 3k6s:B, 3k6s:D, 3k6s:F, 3k6s:H, 3k71:B, 3k71:D, 3k71:F, 3k71:H, 3k72:B, 3k72:D, 4neh:B, 4nen:B, 7usl:B, 7usm:B
9 8tcf:B 359 353 0.2635 0.3955 0.4023 2.24e-96 6om1:B, 6om1:D, 6om1:F, 6om1:H, 6om2:B, 6om2:D, 6uja:B, 6ujb:B, 6ujc:B, 8vs6:B, 8vsd:B, 7y1t:B
10 5b4x:A 710 56 0.0371 0.0282 0.3571 2.68e-04 3a7q:A, 5b4x:C, 2e26:A
11 5b4x:A 710 31 0.0260 0.0197 0.4516 1.9 3a7q:A, 5b4x:C, 2e26:A
12 6xqj:A 173 38 0.0297 0.0925 0.4211 0.004 6xqi:C, 6xqi:B, 6xqi:A, 6xqi:D
13 3maz:A 99 80 0.0408 0.2222 0.2750 1.1
14 2ddu:A 301 29 0.0241 0.0432 0.4483 1.5
15 3elv:A 145 30 0.0278 0.1034 0.5000 1.9 3elv:B
16 6sga:F7 662 75 0.0353 0.0287 0.2533 2.7 7pua:F7, 7pub:F7, 6sgb:F7
17 3mx6:B 260 61 0.0297 0.0615 0.2623 3.5 3mr1:A, 3mr1:B, 3mr1:C, 3mr1:D, 3mx6:A
18 4bs9:A 691 35 0.0223 0.0174 0.3429 7.0
19 1r5a:A 214 48 0.0241 0.0607 0.2708 8.5
20 6a48:A 651 31 0.0223 0.0184 0.3871 9.2

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218