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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
EFLDYKIIALLHDPPNKAWVITGRARNLTQQLSRKHEKVAKYIINQLFGKNYSEKVDNADKLASSIDRYLGSIVYKERSL
FENRSIFLKNILLSNIQRDIGNLFPKDKSKLDNLILEYKKLLNVINKTNLILKYQLFYLIYELVWIDSKYENTPSDTRNP
THTIFDHLYATAAMMNWILSLEKEAKGYLLGIDTIGVADFISKGRKTRDLWISSYLVSALLWYVITWFIEEYGPDVILFP
SLRFNQFYAFYLLEKLRKEGVSEDVIDEIKELITKYIFNGDDLFENLKIPPYPIIPGRITLILPGLIREGEEYKKVQDDN
CFISKVKERYNEGWRKLIEGLRCYSERKREDGFWNLVCRVLKLTEDLLQTTPLNIRVKQVSVTEDEIFNNNKLRSDSWKI
YDNKYRQLVSEFKKSKLVKVTPESRLKLFELTKFDKLPQIGEKSKRGYEFCTSCGVLPAVVIMPKEDELEKKLIDLGIAR
DEKDVRSIKNMISPGERLCPWCLVKRALGAEPRLMRILLLGDLYSVEKIVNEIVSRDVKIEIPSTSDIASIKTFEEMIEK
KNEICEDLKEEEVCEKPSESVLSMWQWFNKNYYNGINLTIDPEEYWFSEKRRRYYFSVFRRHRITFPSPYYALVRADSDY
LGDLLEGKLTPYLAGIIDSGDYANISEKKEEVNKLLEEYLVNAGSGSIVDYVKTVLKCIRENLNKCSCAEKIYSNEVAKV
MFRVNVEKANVEEEVKNSLEYFETILNEGRIIVTPAWHVSISSALNRGLLVELELVNKHKGFVIYAGGDDLLAMLPVDEV
LDFIKESRRAFAGFGTEKLGNMCLENGFVRINNAYYPSLPIVGRSYSVIIAHYADPLFFVINDSYNLLEEGKEIIRYRVM
YNGEYKDAKKDVAIFRYQGLTSVIPLSLKRPIVSSVSDFNEIASIIDVILELKKRIDEGRISVSLLYDYEKYKHLIVASD
EKYLTEFLVKDWIKRNSLRKHVEFTIDEKLYGVRLTIENYPIKIPNDLISNIVYTLRIIYGGE

The query sequence (length=1023) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6s6b:K 1024 1023 1.0000 0.9990 1.0000 0.0 6s8b:K, 6s8e:K, 6s91:K, 6sh8:K, 6shb:K, 6sic:K
2 4w8y:A 835 281 0.0753 0.0922 0.2740 1.24e-13 4w8y:B
3 4w8y:A 835 121 0.0411 0.0503 0.3471 1.46e-10 4w8y:B
4 4w8y:A 835 197 0.0469 0.0575 0.2437 0.52 4w8y:B
5 3w2w:A 618 146 0.0411 0.0680 0.2877 4.18e-09 4h4k:C, 3w2v:A
6 3w2w:A 618 72 0.0274 0.0453 0.3889 1.14e-07 4h4k:C, 3w2v:A
7 4doz:A 557 144 0.0411 0.0754 0.2917 4.69e-09 3ung:C, 3ur3:C
8 4doz:A 557 72 0.0274 0.0503 0.3889 1.47e-07 3ung:C, 3ur3:C
9 4doz:A 557 255 0.0606 0.1113 0.2431 1.4 3ung:C, 3ur3:C
10 3x1l:A 573 136 0.0411 0.0733 0.3088 6.31e-09
11 3x1l:A 573 72 0.0274 0.0489 0.3889 1.02e-07
12 9ash:A 753 38 0.0166 0.0226 0.4474 0.56 9asi:A, 6xn3:A, 6xn4:A, 6xn5:A, 6xn7:A
13 4fhc:A 340 66 0.0176 0.0529 0.2727 0.82 4fhd:A, 4fhe:A, 4fhf:A, 4fhg:A, 4k9r:A, 4rh0:A, 4rh1:A
14 3hkz:A 836 118 0.0283 0.0347 0.2458 1.2 3hkz:I, 2y0s:A, 2y0s:W
15 1jro:A 450 82 0.0254 0.0578 0.3171 3.5 1jro:C, 1jro:E, 1jro:G, 1jrp:A, 1jrp:C, 1jrp:E, 1jrp:G, 2w3r:A, 2w3r:C, 2w3r:E, 2w3r:G, 2w3s:A, 2w3s:C, 2w3s:E, 2w3s:G, 2w54:A, 2w54:C, 2w54:E, 2w54:G, 2w55:A, 2w55:C, 2w55:E, 2w55:G
16 4eys:A 343 96 0.0215 0.0641 0.2292 4.3
17 5y6f:A 226 73 0.0225 0.1018 0.3151 4.6
18 8c5s:A 924 112 0.0244 0.0271 0.2232 4.7 8ap1:A, 8att:A, 8atv:A, 8atw:A, 8c5u:A, 8q63:A, 6ymw:A
19 6muu:A 780 37 0.0137 0.0179 0.3784 5.2 6iqw:A, 6mur:A, 6mus:A, 6mut:A, 6o7e:A, 6o7h:A
20 7o80:Bz 595 83 0.0235 0.0403 0.2892 6.1 7a09:J, 6hcf:k1, 6hcm:k1, 3jag:jj, 3jah:jj, 3jai:jj, 5lzv:jj, 8p03:k, 8p09:k, 8scb:jj, 6yal:k, 6yam:k, 6zme:CI, 6zvj:1
21 8wfx:A 801 40 0.0147 0.0187 0.3750 8.5
22 2x1l:C 476 52 0.0176 0.0378 0.3462 9.1 2x1l:B
23 2x1l:A 511 43 0.0156 0.0313 0.3721 9.3 2x1m:A
24 1nrg:A 213 111 0.0274 0.1315 0.2523 9.8 6h00:A, 3hy8:A, 8qyt:A, 8qyw:A
25 6kc0:A 674 37 0.0147 0.0223 0.4054 9.8 6kbd:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218