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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
EEVVIPKKKTWDKVAILQALASTVHRDSTAAPYVFQDDPYLIPTSSVESHSFLLAKKSGENAAKFIINSYPKYFQKDIAE
PHIPCLMPEYFEPQIEDVSEAALQERIKLQEPSANYNFQQREQSEELEEATEADNEKSKTKAGTWRTKNNAERIFALMPE
KNAHSYCTMIRGMVKHQAPTQALNLYTVLLNNRLRADVYTFNSLIEATALVVNEKFEEKWNNILDLLKQMVTQNVKPNLQ
TFNTILKCLRRFYAFGKLPALQTLREMKAIGIEPSLATYHYVIQLFYQHESPSKGSSLIIYDIMNEVMGKRFSPRDPDDD
MFFQSAMRVCSSLRDLELAYQVHGLLNTGDNWKLIGSDHRRNFYYSKFFNLLCFMEQIDVTLKWYKDLIPSVFFPHSQTM
IDLLQALDVANRLDMVPQIWKDSKEYGHTFRNELKEEILMLMARDQHPPELQVAFADCAADIKSTYESQPEWPASSLNYV
AVLFLRAGRTQEAWKMLGLFRKHNKIPRAELLNEFLDSAKASSSPAQAIELVKLASAFSLPVCEGLTRRVMAEFTLTQEQ
REALGELTALTS

The query sequence (length=572) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6gaw:Ao 572 572 1.0000 1.0000 1.0000 0.0 6gaz:Ao
2 8any:A4 595 593 0.7850 0.7546 0.7572 0.0 8oir:Ae, 8ois:Ae, 7po2:4, 7qi4:A4, 7qi5:A4, 7qi6:A4, 6zm5:A4, 6zm6:A4
3 7pnt:4 589 589 0.7430 0.7216 0.7216 0.0 7pnu:4, 7pnv:4, 7pnw:4
4 3jd5:o 461 265 0.3549 0.4403 0.7660 1.09e-140
5 3jd5:o 461 88 0.1486 0.1844 0.9659 2.19e-51
6 5aj3:o 476 267 0.1661 0.1996 0.3558 1.98e-83 5aj3:e, 5aj4:Ae, 5aj4:Bz, 5aj4:Ao, 5apn:z, 5apo:z, 4ce4:x, 4ce4:z, 5flc:C, 5flc:G, 6hiv:UD, 6hix:UD, 6sg9:Ui, 6sgb:UO, 6sgb:Ui, 7z34:oC
7 5i9f:A 388 294 0.1206 0.1778 0.2347 1.34e-12 5i9g:C
8 5i9f:A 388 265 0.1066 0.1572 0.2302 1.07e-11 5i9g:C
9 5i9f:A 388 150 0.0804 0.1186 0.3067 1.46e-11 5i9g:C
10 5i9f:A 388 150 0.0804 0.1186 0.3067 4.14e-11 5i9g:C
11 5i9f:A 388 120 0.0559 0.0825 0.2667 5.37e-05 5i9g:C
12 5i9h:A 368 269 0.1066 0.1658 0.2268 8.14e-12 5i9d:A
13 5i9h:A 368 292 0.1206 0.1875 0.2363 3.41e-11 5i9d:A
14 5i9h:A 368 154 0.0822 0.1277 0.3052 2.18e-10 5i9d:A
15 6een:A 315 305 0.1171 0.2127 0.2197 6.29e-11 6een:B, 6een:C, 6een:D
16 6een:A 315 264 0.1084 0.1968 0.2348 7.19e-10 6een:B, 6een:C, 6een:D
17 6een:A 315 132 0.0664 0.1206 0.2879 4.81e-08 6een:B, 6een:C, 6een:D
18 4m59:A 687 139 0.0664 0.0553 0.2734 1.06e-04 4m59:B, 4oe1:A, 4oe1:B
19 4m59:A 687 125 0.0507 0.0422 0.2320 0.001 4m59:B, 4oe1:A, 4oe1:B
20 4m59:A 687 103 0.0350 0.0291 0.1942 0.12 4m59:B, 4oe1:A, 4oe1:B
21 4m59:A 687 89 0.0402 0.0335 0.2584 0.63 4m59:B, 4oe1:A, 4oe1:B
22 4g23:A 476 106 0.0559 0.0672 0.3019 0.049 6bv5:A, 6bv6:A, 6bv8:A, 6bv9:A, 4g24:A, 4g25:A, 4g26:A, 6lvr:C, 6lvr:A
23 2dby:A 355 149 0.0647 0.1042 0.2483 1.5
24 4xa7:A 226 65 0.0332 0.0841 0.2923 2.2
25 5ds0:C 359 47 0.0280 0.0446 0.3404 3.0 5ds0:A, 5ds0:B, 5ds0:D, 5ds0:E, 5ds0:F, 5ds0:G, 5ds0:H, 5ds0:I, 5ds0:J, 5ds0:K, 5ds0:L
26 8iua:A 555 44 0.0262 0.0270 0.3409 4.4 8iu9:A, 8iub:A
27 6xyw:AQ 366 154 0.0577 0.0902 0.2143 5.2
28 7oq4:E 72 36 0.0245 0.1944 0.3889 7.0
29 4ntk:A 121 63 0.0367 0.1736 0.3333 7.1 4ntk:E, 4ntk:B, 4ntk:C, 4ntk:D, 4ntk:F, 4ntm:A, 4ntm:E, 4ntm:B, 4ntm:C, 4ntm:D, 4ntm:F, 4ntn:A, 4ntn:B, 4ntn:C, 4ntn:D, 4ntn:E, 4ntn:F, 3qn0:A, 3qn0:B, 3qn0:C, 3qn0:D, 3qn0:E, 3qn0:F, 3qn9:A, 3qn9:B, 3qna:A, 3qna:B, 3qna:C, 3qna:D, 3qna:E, 3qna:F
30 8eju:B 257 34 0.0210 0.0467 0.3529 7.1 8eju:A
31 4rav:B 110 51 0.0315 0.1636 0.3529 9.5 4rav:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218