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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
EDAVRIVIQKSLEANGLVRGLSEVARTLDCKTAHMCILADDCEDEEYKKLVTALAKQGNIDLINVEEREKLAQWAGLVRR
DAGEVTKTLKCSSVAIRD

The query sequence (length=98) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6az1:Q 115 99 0.9898 0.8435 0.9798 2.77e-64 8ovj:SQ, 8rxh:SQ, 8rxx:SQ
2 7ase:h 121 99 0.7653 0.6198 0.7576 1.46e-50 5opt:i
3 4v8m:AF 121 99 0.7245 0.5868 0.7172 2.12e-45 8ova:AF
4 7olc:SM 118 98 0.4490 0.3729 0.4490 4.25e-23 7old:SM, 8oo0:SM, 7r81:N2, 7z3n:SM, 7z3o:SM
5 4v7e:BM 123 97 0.3878 0.3089 0.3918 6.94e-21 8r57:M
6 6zj3:SQ 122 97 0.4082 0.3279 0.4124 2.78e-20
7 4v6w:AM 119 97 0.4286 0.3529 0.4330 2.97e-20 6xu6:AM, 6xu7:AM, 6xu8:AM
8 7a01:e3 124 97 0.3980 0.3145 0.4021 5.09e-20 7a09:v, 5a2q:M, 5aj0:BM, 9bdl:AS12, 9bdn:AS12, 9bdp:AS12, 8bhf:N3, 9bkd:m, 9bln:m, 8btk:Al, 4d5l:M, 4d61:M, 6d90:NN, 6d9j:NN, 9f1b:Al, 9f1c:Al, 9f1d:Al, 6fec:r, 5flx:M, 6g18:M, 6g51:M, 6g53:M, 6g5h:M, 6g5i:M, 8g5y:SM, 8g5z:SM, 8g60:SM, 8g61:SM, 8g6j:SM, 8glp:SM, 6gz3:BM, 6gz4:BM, 6gz5:BM, 6hcf:N1, 6hcj:N2, 6hcm:N1, 6hcq:N2, 8ifd:3J, 8ife:3J, 6ip5:3J, 6ip6:3J, 6ip8:3J, 3j7p:SM, 3j7r:SM, 3jag:MM, 3jah:MM, 3jai:MM, 3jaj:SM, 3jan:SM, 7jqb:N, 7jqc:N, 5k0y:r, 8k2c:SM, 7k5i:M, 4kzx:M, 4kzy:M, 4kzz:M, 5lks:SM, 7ls1:M3, 7ls2:M3, 5lzs:MM, 5lzt:MM, 5lzu:MM, 5lzv:MM, 5lzw:MM, 5lzx:MM, 5lzy:MM, 5lzz:MM, 7mdz:MM, 7mq8:LA, 7mq9:LA, 7mqa:LA, 6mtb:MM, 6mtc:MM, 6mtd:MM, 6mte:MM, 7nwg:N2, 7nwh:MM, 7nwi:MM, 7o7y:Al, 7o7z:Al, 7o80:Al, 7o81:Al, 5oa3:M, 6ole:SM, 6olf:SM, 6olg:BM, 6oli:SM, 6olz:BM, 6om0:SM, 6om7:SM, 8oz0:q, 8p03:O, 8p09:O, 8p2k:Al, 6p4g:N, 6p4h:N, 6p5i:N, 6p5j:N, 6p5k:N, 6p5n:N, 8pj1:m, 8pj2:m, 8pj3:m, 8pj4:m, 8pj5:m, 8pj6:m, 8ppk:M, 8ppl:AM, 8q7z:Al, 8q87:Al, 7qgg:SM, 8qoi:SM, 7qp6:m, 7qp7:m, 6qzp:SM, 7r4x:M, 6r5q:RR, 6r6g:RR, 6r6p:RR, 6r7q:RR, 8scb:MM, 6sgc:N1, 7syg:N, 7syh:N, 7syi:N, 7syj:N, 7syk:N, 7syl:N, 7sym:N, 7syn:N, 7syo:N, 7syp:N, 7syq:N, 7syr:N, 7sys:N, 7syt:N, 7syu:N, 7syv:N, 7syw:N, 7syx:N, 5t2c:AM, 8t4s:M, 7toq:AS12, 7tor:AS12, 7tql:O, 4ug0:SM, 4ujc:CM, 4ujd:CM, 4uje:BM, 4v6x:AM, 5vyc:M1, 5vyc:M2, 5vyc:M3, 5vyc:M4, 5vyc:M5, 5vyc:M6, 6w2s:N, 6w2t:N, 7wtt:M, 7wtu:M, 7wtv:M, 7wtw:M, 7wtx:M, 7wtz:M, 7wu0:M, 6xa1:SM, 7xnx:SM, 7xny:SM, 8xsx:SM, 8xsy:SM, 8xsz:SM, 8xxl:SM, 8xxm:SM, 8xxn:SM, 6y0g:SM, 6yal:O, 6yam:O, 6yan:O, 6ybs:m, 8yoo:SM, 8yop:SM, 6z6l:SM, 6z6m:SM, 6z6n:SM, 7zjw:SX, 7zjx:SX, 6zlw:O, 6zm7:SM, 6zme:SM, 6zmi:SM, 6zmo:SM, 6zmt:O, 6zmw:m, 6zn5:O, 6zoj:M, 6zol:M, 6zon:v, 6zp4:v, 6zuo:M, 6zv6:M, 6zvh:M, 6zvj:v, 6zvk:e3, 6zxd:M, 6zxe:M, 6zxf:M, 6zxg:M, 6zxh:M
9 8auv:C 117 80 0.3367 0.2821 0.4125 6.58e-17 8b2l:C1
10 9bh5:AM 117 99 0.3469 0.2906 0.3434 9.40e-15 9cai:AM
11 8i7j:M 122 81 0.3163 0.2541 0.3827 1.35e-13 6fyx:M, 6fyy:M, 6gsm:M, 6gsn:M, 5it7:M, 5it9:M, 3j80:M, 3j81:M, 3jam:M, 3jap:M, 8rw1:M, 8s8d:M, 8s8e:M, 8s8f:M, 8s8g:M, 8s8h:M, 8s8i:M, 8s8j:M, 6uz7:M
12 8c3a:CZ 119 101 0.3776 0.3109 0.3663 1.70e-13 8c3a:O, 8cq7:O, 8cq7:CZ, 8cqw:O, 8cqw:CZ, 8cre:O, 8cre:CZ, 8oeq:O, 8oeq:CZ, 7pzy:N, 7q08:N, 7q0f:N, 7q0p:N, 7q0r:N
13 4bts:AU 124 92 0.3571 0.2823 0.3804 4.97e-13 4bts:BU, 4bts:CU, 4bts:DU, 4v5o:AU, 4v5o:BU
14 8cbj:M 125 83 0.2857 0.2240 0.3373 3.23e-08 7a1g:D, 7b7d:D, 8bqd:D, 8bqx:D, 8cah:D, 8cas:F, 7d5s:SN, 5dat:C2, 5dat:c2, 5dc3:C2, 5dc3:c2, 5dge:C2, 5dge:c2, 5dgf:C2, 5dgf:c2, 5dgv:C2, 5dgv:c2, 6eml:D, 8eub:BM, 8evp:BM, 8evq:BM, 8evr:BM, 8evs:BM, 8evt:BM, 8ewb:BM, 8ewc:BM, 6fai:M, 5fcj:C2, 5fcj:c2, 6gq1:AC, 6gqb:AC, 6gqv:AC, 6hhq:N, 6hhq:c2, 5i4l:C2, 5i4l:c2, 6i7o:D, 6i7o:Db, 3j6x:12, 3j6y:12, 3j77:12, 3j78:12, 5juo:JB, 5jup:JB, 5jus:JB, 5jut:JB, 5juu:JB, 8k2d:SM, 8k82:SM, 6ke6:SN, 6lqp:SN, 6lqu:SN, 5lyb:C2, 5m1j:M2, 5mc6:D, 5mei:c2, 5mei:N, 7mpi:BM, 7mpj:BM, 7n8b:BM, 5ndg:C2, 5ndg:c2, 5ndv:c2, 5ndw:C2, 5ndw:c2, 7nrc:SD, 7nrd:SD, 5obm:C2, 5obm:c2, 5on6:c2, 5on6:N, 7osa:eS12, 6q8y:D, 6rbd:M, 6rbe:M, 7rr5:SM, 6s47:BN, 6snt:M, 6sv4:D, 6sv4:Db, 6sv4:Dc, 6t4q:SM, 6t7i:SM, 6t7t:SM, 6t83:Mb, 6t83:n, 5tbw:N, 5tbw:c2, 6tb3:D, 5tga:C2, 5tga:c2, 5tgm:C2, 5tgm:c2, 6tnu:D, 4u3m:C2, 4u3m:c2, 4u3n:C2, 4u3n:c2, 4u3u:C2, 4u3u:c2, 4u4n:C2, 4u4n:c2, 4u4o:C2, 4u4o:c2, 4u4q:C2, 4u4q:c2, 4u4r:C2, 4u4r:c2, 4u4u:C2, 4u4u:c2, 4u4y:C2, 4u4y:c2, 4u4z:C2, 4u4z:c2, 4u50:C2, 4u50:c2, 4u51:C2, 4u51:c2, 4u52:C2, 4u52:c2, 4u53:C2, 4u53:c2, 4u55:C2, 4u55:c2, 4u56:C2, 4u56:c2, 4u6f:C2, 4u6f:c2, 4uer:U, 4v88:AM, 4v88:CM, 4v8y:AM, 4v8z:AM, 6wdr:M, 6woo:MM, 5wyj:SN, 6y7c:M, 6z6j:SM, 6z6k:SM, 6zce:N, 7zpq:AM, 7zrs:AM, 6zu9:F, 7zuw:AM, 7zux:DM, 6zvi:u, 7zw0:sD
15 7qvp:Rf 78 96 0.3265 0.4103 0.3333 4.33e-08 6y57:Sf
16 5xyi:M 103 64 0.2551 0.2427 0.3906 1.48e-07
17 8fvy:M 103 86 0.2857 0.2718 0.3256 6.75e-07 8g4s:M
18 5fci:C2 124 76 0.2449 0.1935 0.3158 7.63e-06 5fci:c2, 5lyb:c2
19 5ndv:C2 102 75 0.2347 0.2255 0.3067 2.23e-05
20 8p5d:SM0 113 84 0.2653 0.2301 0.3095 3.82e-05 8p60:SM0, 8p60:RM0, 7qca:SM0
21 6rm3:SM0 119 73 0.2143 0.1765 0.2877 6.21e-04
22 3cc2:F 119 59 0.1633 0.1345 0.2712 0.001 3cc4:F, 3cc7:F, 3cce:F, 3ccj:F, 3ccl:F, 3ccm:F, 3ccq:F, 3ccr:F, 3ccs:F, 3ccu:F, 3ccv:F, 3cd6:F, 3cma:F, 3cme:F, 3cpw:F, 3cxc:F, 3g4s:F, 3g6e:F, 3g71:F, 3i55:F, 3i56:F, 1jj2:F, 1k73:H, 1k8a:H, 1k9m:H, 1kc8:H, 1kd1:H, 1kqs:F, 1m1k:H, 1m90:H, 1n8r:H, 1nji:H, 2otj:F, 2otl:F, 3ow2:F, 1q7y:H, 1q81:H, 1q82:H, 1q86:H, 2qa4:F, 2qex:F, 1qvf:F, 1qvg:F, 1s72:F, 4v9f:F, 1vq4:F, 1vq5:F, 1vq6:F, 1vq7:F, 1vq8:F, 1vq9:F, 1vqk:F, 1vql:F, 1vqm:F, 1vqn:F, 1vqo:F, 1vqp:F, 1w2b:F, 1yhq:F, 1yi2:F, 1yij:F, 1yit:F, 1yj9:F, 1yjn:F, 1yjw:F
23 2ale:A 132 73 0.2041 0.1515 0.2740 0.013 7ajt:CF, 7ajt:CG, 7aju:CF, 7aju:CG, 7d4i:3G, 7d4i:3H, 7d5s:3G, 7d5s:3H, 7d5t:3G, 7d5t:3H, 7d63:3G, 7d63:3H, 5gan:K, 5gap:K, 3jcm:M, 6ke6:3G, 6ke6:3H, 6lqp:3G, 6lqp:3H, 6lqq:3G, 6lqq:3H, 6lqr:3G, 6lqr:3H, 6lqs:3G, 6lqs:3H, 6lqt:3G, 6lqt:3H, 6lqu:3G, 6lqu:3H, 6lqv:3G, 6lqv:3H, 6nd4:e, 6nd4:f, 5nrl:K, 4nut:A, 7suk:SE, 7suk:SF, 5tzs:f, 5wlc:SE, 5wlc:SF, 5wyj:3G, 5wyj:3H, 5wyk:3G, 5wyk:3H, 6zqa:CF, 6zqb:CF, 6zqb:CG, 6zqc:CF, 6zqc:CG, 6zqd:CF, 6zqd:CG, 6zqe:CF, 6zqe:CG, 5zwm:M, 5zwo:M
24 4v8m:Bx 240 60 0.1735 0.0708 0.2833 0.090 8ova:Bx, 8ove:Bx, 5t5h:x
25 6tmf:b 123 76 0.2041 0.1626 0.2632 0.090
26 6k0a:I 116 75 0.2143 0.1810 0.2800 0.12 6k0a:J, 6k0b:I, 6k0b:J, 1sds:A, 1sds:C, 1sds:B
27 3siv:A 128 73 0.1735 0.1328 0.2329 0.33 6ah0:M, 6ahd:M, 1e7k:A, 1e7k:B, 8h6e:4E, 8h6j:4E, 8h6k:4E, 8h6l:4E, 7mq8:SE, 7mq8:SF, 7mq9:SE, 7mq9:SF, 7mqa:SE, 7mqa:SF, 5o9z:O, 2ozb:A, 2ozb:D, 8q7n:M, 8qo9:M, 8qoz:M, 8qpa:M, 8qpb:M, 8qpe:M, 6qw6:4D, 6qx9:4D, 8qxd:M, 8qzs:M, 8r08:M, 8r09:M, 8r0a:M, 8r0b:M, 8rm5:M, 3siu:A, 3siu:D, 3siv:D, 3siv:J, 3siv:G, 8y6o:O
28 7qep:C2 118 82 0.2041 0.1695 0.2439 1.3
29 5lf2:A 302 58 0.2041 0.0662 0.3448 1.5 5lf2:B
30 4ohb:A 159 30 0.1020 0.0629 0.3333 2.0 4jem:A, 4jem:B
31 5y7m:A 125 54 0.1327 0.1040 0.2407 6.5 4by9:G, 4by9:J, 4by9:D, 4by9:M, 5dcv:A, 5dcv:C, 3hax:D, 3hay:D, 3hjw:C, 2hvy:D, 5jb3:3, 5jbh:3, 3lwo:C, 3lwp:C, 3lwq:C, 3lwr:C, 3lwv:C, 3nmu:G, 3nmu:C, 3nvi:B, 3nvi:D, 3nvk:E, 3nvk:H, 7ozq:B, 7ozq:D, 7ozq:C, 7ozq:A, 6skf:BH, 6skf:BI, 6skg:BH, 6skg:BI, 6sw9:3, 6swc:3, 6swe:3, 6th6:BH, 6th6:BI, 6tph:A, 4v4n:B3, 4v4n:AG, 4v6u:A3, 4v6u:BG, 4v6u:B4, 5xtm:A, 5xtm:C, 5y7m:C, 7zag:3, 7zah:3, 7zai:3, 7zhg:3

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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