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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
DVTVEMEADAVLDAEIALGKALPPVTGALRTILLTGATGFLGAFLLEELCRRTDARIYCLVRSKTQEGMNRIRKNLESYS
LWNEALAPRIVPVRGDIGQPLLGLSEKEFQRLSEEIDAIYHNGALVNFLYPYESMRAANVLGTREILRLATRTRIKPLHY
VSTVSVLPLGRKAPIREDEPLEGPSSLVGGYAQSKWVAEKLVREASRRGLPVTILRPGRVTGHSRTGAWNTDDLVCRTLK
GCVRMGVAPSVDALLDLTPVDYVSSAIVDLSMRPESIGQTYHLVNPQFVRADEMWNYMRAFGYGLRVLPYDQWLSELGSA
ASSDSELGDLLMFLQQVDRSVGGPRMVVCDSGDTLKALGGTGTSCPSVDASLISTYLSSLVHRGFLKAPE

The query sequence (length=390) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4u7w:B 394 394 1.0000 0.9898 0.9898 0.0 4u7w:A
2 5msu:B 459 423 0.3359 0.2854 0.3097 2.89e-41 5mso:A, 5msu:C, 5msu:A
3 5msr:B 520 422 0.3282 0.2462 0.3033 1.78e-39 5msp:A, 5msr:A, 5msr:C, 5msr:D, 5msv:A, 5msv:B, 5msv:C, 5msv:D
4 6vtj:A 472 301 0.2256 0.1864 0.2924 2.53e-29
5 6nki:A 356 251 0.1949 0.2135 0.3028 8.33e-22
6 7eoz:A 482 152 0.1026 0.0830 0.2632 1.38e-07 7eoz:B
7 5u4q:A 321 251 0.1821 0.2212 0.2829 1.45e-07
8 5u4q:B 304 247 0.1744 0.2237 0.2753 1.65e-06
9 8v4h:B 342 272 0.1487 0.1696 0.2132 5.50e-06 8v4g:A, 8v4g:B, 8v4h:A
10 6zll:A 321 196 0.1128 0.1371 0.2245 2.97e-04 6zl6:A, 6zl6:B, 6zla:A, 6zla:B, 6zla:C, 6zla:D, 6zld:A, 6zld:B, 6zlj:A, 6zlj:B, 6zlk:A, 6zlk:B, 6zlk:C, 6zlk:D, 6zll:B, 6zll:C, 6zll:D
11 6vlo:A 319 264 0.1641 0.2006 0.2424 7.58e-04 6vlo:B, 6vlo:C, 6vlo:D
12 1ker:B 347 158 0.1128 0.1268 0.2785 0.002 1kep:A, 1kep:B, 1ker:A, 1ket:A, 1ket:B, 1oc2:A, 1oc2:B
13 4j2o:C 316 208 0.1308 0.1614 0.2452 0.005 4j2o:A, 4j2o:B, 4j2o:D, 4j2o:E, 4j2o:F
14 3ehe:A 290 171 0.1077 0.1448 0.2456 0.12 3ehe:B
15 8vr2:B 321 270 0.1436 0.1745 0.2074 0.15 8vr2:A, 8vr2:C, 8vr2:D
16 4ej0:A 330 175 0.1026 0.1212 0.2286 0.16 4ej0:B, 4ej0:C, 4ej0:D, 4ej0:E, 4ej0:F, 4ej0:G, 4ej0:H, 4ej0:I, 4ej0:J
17 8ewu:B 354 86 0.0564 0.0621 0.2558 0.23 8ewu:A
18 6bwl:A 313 203 0.1308 0.1629 0.2512 0.25
19 8b9z:P 377 267 0.1590 0.1645 0.2322 0.25 8ba0:P, 8esw:A9, 8esz:A9
20 6s6y:D 308 65 0.0564 0.0714 0.3385 0.34 6s6y:L, 6s6y:P
21 3e8x:A 214 263 0.1513 0.2757 0.2243 0.38
22 1r66:A 322 189 0.1333 0.1615 0.2751 0.47 1r6d:A
23 3w1v:A 347 139 0.0821 0.0922 0.2302 0.51 4g5h:A, 3vvc:A, 3w1v:B
24 3vvb:A 270 139 0.0821 0.1185 0.2302 0.51
25 4r1s:A 319 262 0.1513 0.1850 0.2252 0.76 4r1s:B
26 3slk:A 747 60 0.0538 0.0281 0.3500 0.94 3slk:B
27 3st7:A 369 39 0.0359 0.0379 0.3590 1.0 2zkl:A
28 4yrd:B 346 39 0.0359 0.0405 0.3590 1.2 3vhr:A, 4yrd:A
29 3enk:A 340 181 0.1128 0.1294 0.2431 1.2 3enk:B
30 3fl2:A 116 48 0.0462 0.1552 0.3750 1.4
31 3vps:A 303 180 0.1103 0.1419 0.2389 1.6 3vps:B
32 6bi4:C 311 188 0.1179 0.1479 0.2447 1.8 6bi4:B, 6bi4:D, 6bi4:A
33 8du1:A 361 209 0.1154 0.1247 0.2153 2.2 8du1:B, 8du1:C, 8du1:D
34 2jl1:A 287 72 0.0641 0.0871 0.3472 2.9 2vrb:A
35 4glw:B 281 32 0.0333 0.0463 0.4062 3.0 4glw:A
36 1izl:N 277 41 0.0385 0.0542 0.3659 3.9 1izl:D
37 4hjw:C 378 91 0.0692 0.0714 0.2967 6.3 4hjw:A, 4hjw:B
38 1gy8:C 370 215 0.1231 0.1297 0.2233 6.8 2cnb:A, 2cnb:B, 2cnb:C, 2cnb:D, 1gy8:A, 1gy8:B, 1gy8:D
39 1bsv:A 317 102 0.0667 0.0820 0.2549 7.1 1bws:A, 1e6u:A, 1e7q:A, 1e7r:A, 1e7s:A, 1fxs:A
40 3o3f:A 222 116 0.0744 0.1306 0.2500 7.5 2etj:A, 4hht:A, 3o3g:A, 3o3h:A
41 4bed:B 1734 138 0.0795 0.0179 0.2246 7.6 4bed:D, 3qjo:A, 3qjo:B
42 2gn4:A 329 141 0.0846 0.1003 0.2340 8.0 2gn4:B, 2gn6:A, 2gn6:B, 2gn8:A, 2gn8:B, 2gn9:A, 2gn9:B, 2gna:A, 2gna:B
43 3sxp:D 314 100 0.0641 0.0796 0.2500 8.1 3sxp:A, 3sxp:B, 3sxp:C, 3sxp:E
44 6nbr:A 316 183 0.1026 0.1266 0.2186 9.3 6nbr:B, 6nbr:C, 6nbr:D
45 3g6w:A 215 93 0.0564 0.1023 0.2366 9.8 3g6w:B, 3g6w:D, 3g6w:C, 1vst:A, 1xtt:A, 1xtt:B, 1xtt:C, 1xtt:D, 1xtu:A, 1xtu:H, 1xtu:B, 1xtu:C, 1xtu:F, 1xtu:G, 1xtu:D, 1xtu:E, 1xtv:A, 1xtv:C, 1xtv:E, 1xtv:G

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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