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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
DTMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQIS
ERDVLCVQIAGLCRNLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQI
VGPLESPVLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKE
VGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTD
PKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPI
DHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQK
KEWN

The query sequence (length=484) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4mz7:B 493 484 0.9897 0.9716 0.9897 0.0 7a5y:A, 7a5y:B, 7a5y:C, 7a5y:D, 7a5y:E, 7a5y:F, 7a5y:G, 7a5y:H, 5ao0:A, 5ao0:B, 5ao1:A, 5ao1:B, 5ao1:C, 5ao1:D, 5ao2:A, 5ao2:B, 5ao2:C, 5ao2:D, 5ao3:A, 5ao3:C, 5ao3:B, 5ao3:D, 5ao4:A, 5ao4:B, 4bzb:A, 4bzb:C, 4bzb:D, 4bzb:B, 4bzc:A, 4bzc:C, 4bzc:D, 4bzc:B, 6cm2:D, 6cm2:A, 6cm2:B, 6cm2:C, 8d94:A, 8d94:D, 8d94:B, 8d94:C, 8d9j:A, 8d9j:D, 8d9j:B, 8d9j:C, 6dw3:D, 6dw3:C, 6dw3:B, 6dw3:A, 6dw4:D, 6dw4:C, 6dw4:B, 6dw4:A, 6dw5:A, 6dw5:D, 6dw5:B, 6dw5:C, 6dw7:A, 6dw7:B, 6dw7:C, 6dw7:D, 6dwd:D, 6dwd:A, 6dwd:C, 6dwd:B, 6dwj:D, 6dwj:A, 6dwj:C, 6dwj:B, 6dwk:A, 6dwk:D, 6dwk:B, 6dwk:C, 8gb1:A, 8gb1:B, 8gb1:C, 8gb1:D, 8gb2:D, 8gb2:A, 8gb2:B, 8gb2:C, 7ltt:A, 7ltt:D, 7ltt:B, 7ltt:C, 7lu5:A, 7lu5:D, 7lu5:C, 7lu5:B, 7lu5:E, 7lu5:H, 7lu5:F, 7lu5:G, 7lu5:I, 7lu5:L, 7lu5:K, 7lu5:J, 7lu5:M, 7lu5:P, 7lu5:O, 7lu5:N, 4mz7:A, 4q7h:A, 4q7h:B, 4q7h:C, 4q7h:D, 4qfx:A, 4qfx:D, 4qfx:B, 4qfx:C, 4qfy:A, 4qfy:D, 4qfy:B, 4qfy:C, 4qfz:A, 4qfz:D, 4qfz:B, 4qfz:C, 4qg0:A, 4qg0:D, 4qg0:B, 4qg0:C, 4qg1:A, 4qg1:B, 4qg1:C, 4qg1:D, 4qg2:A, 4qg2:D, 4qg2:B, 4qg2:C, 4qg4:A, 4qg4:D, 4qg4:B, 4qg4:C, 8qxj:A, 8qxj:B, 8qxj:C, 8qxj:D, 8qxk:A, 8qxk:B, 8qxk:C, 8qxk:D, 8qxl:A, 8qxl:B, 8qxl:C, 8qxl:D, 8qxm:A, 8qxm:C, 8qxm:B, 8qxm:D, 8qxn:A, 8qxn:B, 8qxn:C, 8qxn:D, 8qxo:A, 8qxo:B, 8qxo:D, 8qxo:C, 4rxo:A, 4rxo:B, 4rxo:C, 4rxo:D, 4rxp:A, 4rxp:B, 4rxq:A, 4rxq:B, 4rxr:A, 4rxr:B, 4rxs:A, 4rxs:B, 7s2y:A, 7s2y:B, 7s2y:C, 7s2y:D, 8tdv:A, 8tdv:B, 8tdw:A, 8tdw:B, 4tnp:A, 4tnp:C, 4tnp:D, 4tnp:B, 4tnq:A, 4tnq:D, 4tnq:C, 4tnq:B, 4tnr:D, 4tnr:A, 4tnr:C, 4tnr:B, 4tnx:A, 4tnx:C, 4tnx:D, 4tnx:B, 4tny:A, 4tny:C, 4tny:B, 4tny:D, 4tnz:C, 4tnz:B, 4tnz:A, 4tnz:D, 4to0:A, 4to0:D, 4to0:C, 4to0:B, 4to1:A, 4to1:B, 4to1:C, 4to1:D, 4to2:A, 4to2:D, 4to2:B, 4to2:C, 4to3:A, 4to3:D, 4to3:B, 4to3:C, 4to4:A, 4to4:D, 4to4:B, 4to4:C, 4to5:A, 4to5:D, 4to5:C, 4to5:B, 4to6:A, 4to6:D, 4to6:B, 4to6:C, 6tx0:A, 6tx0:B, 6txa:A, 6txa:B, 6txa:D, 6txa:C, 6txa:E, 6txa:F, 6txa:H, 6txa:G, 6txa:I, 6txa:L, 6txa:J, 6txa:K, 6txa:M, 6txa:N, 6txa:P, 6txa:O, 6txc:A, 6txc:B, 6txc:D, 6txc:C, 6txc:E, 6txc:F, 6txc:H, 6txc:G, 6txc:I, 6txc:J, 6txc:L, 6txc:K, 6txc:M, 6txc:N, 6txc:P, 6txc:O, 6txe:A, 6txe:B, 6txe:C, 6txe:D, 6txe:E, 6txe:F, 6txe:G, 6txe:H, 6txe:I, 6txe:J, 6txe:K, 6txe:L, 6txe:M, 6txe:N, 6txe:P, 6txe:O, 6txf:A, 6txf:B, 3u1n:A, 3u1n:B, 3u1n:C, 3u1n:D, 6u6x:A, 6u6x:D, 6u6y:A, 6u6y:D, 6u6y:B, 6u6y:C, 6u6z:A, 6u6z:D, 6u6z:B, 6u6z:C, 7ujn:A, 7ujn:B, 7ujn:C, 7ujn:D, 6xu1:A, 6xu1:B, 6xu1:C, 6xu1:D, 6xu1:E, 6xu1:F, 6xu1:G, 6xu1:H, 6yom:A, 6yom:B, 4zwe:A, 4zwe:C, 4zwe:D, 4zwe:B, 4zwg:A, 4zwg:D, 4zwg:B, 4zwg:C
2 5yhw:A 453 473 0.8244 0.8808 0.8436 0.0 5yhw:B, 5yhw:C, 5yhw:F
3 5ao4:C 389 463 0.7975 0.9923 0.8337 0.0 5ao4:D, 6u6x:B
4 6u6x:C 376 463 0.7707 0.9920 0.8056 0.0
5 6brh:B 502 475 0.7107 0.6853 0.7242 0.0 6brg:A, 6brg:B, 6brg:C, 6brg:D, 6brh:A, 6brk:A
6 5yhw:D 387 439 0.7128 0.8915 0.7859 0.0 5yhw:H, 5yhw:E, 5yhw:G
7 6pwy:B 513 445 0.3058 0.2885 0.3326 5.02e-63 6pwy:A, 6pwy:D, 6pwy:C
8 2hek:A 369 276 0.1777 0.2331 0.3116 7.45e-27 2hek:B
9 2q14:C 406 368 0.2066 0.2463 0.2717 1.14e-26 2q14:A, 2q14:B, 2q14:D, 2q14:E, 2q14:F, 2q14:G, 2q14:H
10 4lrl:C 455 235 0.1343 0.1429 0.2766 5.02e-17 3irh:A, 3irh:B, 3irh:C, 3irh:D, 4lrl:A, 4lrl:B, 4lrl:D, 2o6i:A, 2o6i:B
11 2dqb:C 364 112 0.0620 0.0824 0.2679 0.008 2dqb:A, 2dqb:B, 2dqb:D, 2dqb:E, 2dqb:F
12 8tww:A 244 95 0.0413 0.0820 0.2105 0.033 8ji2:A, 8ji2:B, 8ji3:A, 8ji3:B, 8ji4:A, 8ji4:B, 8ji5:A, 8ji5:B, 8ji6:A, 8ji6:B, 8ji7:A, 8ji7:B, 8twn:A, 8twt:A, 8twt:B, 8tww:B
13 4wad:A 498 206 0.1095 0.1064 0.2573 0.93 4x6l:A, 4x6l:B, 4x6l:C, 4x7m:A, 4x7m:B, 4x7r:A, 4x7r:B
14 8d8j:d 660 70 0.0393 0.0288 0.2714 4.6 8d8k:d
15 6a8l:A 183 90 0.0434 0.1148 0.2333 7.6 6a8l:B, 5zn8:A, 5zn8:B
16 6j5w:A 816 31 0.0289 0.0172 0.4516 8.0 6j5t:G, 6j5t:C, 6j5t:F, 6j5t:L, 6j5t:O, 6j6i:C, 6j6i:F, 6j6i:G, 6j6i:L, 6j6i:O
17 6jp9:A 298 43 0.0269 0.0436 0.3023 9.8 6jp9:B, 6jp9:C, 6jp9:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218