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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
DSFVAHFREAAPYIRQMRGTTLVAGIDGRLLEGGTLNKLAADIGLLSQLGIRLVLIHGAYHFLDRLAAAQGRTPHYCRGL
RVTDETSLGQAQQFAGTVRSRFEAALCGSSVPLVSGNFLTARPIGVIDGTDMEYAGVIRKTDTAALRFQLDAGNIVWMPP
LGHSYGGKTFNLDMVQAAASVAVSLQAEKLVYLTLSDGISRPDGTLAETLSAQEAQSLAEHAASETRRLISSAVAALEGG
VHRVQILNGAADGSLLQELFTRNGIGTSIAKEAFVSIRQAHSGDIPHIAALIRPLEEQGILLHRSREYLENHISEFSILE
HDGNLYGCAALKTFAEADCGEIACLAVSPQAQDGGYGERLLAHIIDKARGIGISRLFALSTNTGEWFAERGFQTASEDEL
PETRRKDYRSNGRNSHILVRRLHR

The query sequence (length=424) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3b8g:A 424 424 1.0000 1.0000 1.0000 0.0 3d2m:A, 3d2p:A, 3d2p:B, 4i49:A, 2r8v:A, 2r98:A
2 2bty:A 282 275 0.1934 0.2908 0.2982 1.04e-28 2bty:B, 2bty:C
3 2buf:C 298 283 0.1792 0.2550 0.2686 7.38e-19 2buf:A, 2buf:B, 2buf:D, 2buf:E, 2buf:F, 2buf:G, 2buf:H, 2buf:I, 2buf:J, 2buf:L
4 2v5h:B 289 285 0.1745 0.2561 0.2596 3.19e-17 2jj4:A, 2jj4:B, 2v5h:A, 2v5h:C, 2v5h:D, 2v5h:E, 2v5h:F
5 2buf:K 273 275 0.1769 0.2747 0.2727 7.87e-15
6 2rd5:B 283 281 0.1745 0.2615 0.2633 2.39e-14 2rd5:A, 4usj:A, 4usj:B
7 2ap9:A 299 285 0.1910 0.2709 0.2842 4.99e-12 7nln:A, 7nln:B, 7nlo:A, 7nlp:A, 7nlr:A, 7nlt:A, 7nlw:A, 7nlx:A, 7nly:A, 7nlz:A, 7nm0:A, 7nn8:A, 7nnb:A
8 5yge:A 169 119 0.0920 0.2308 0.3277 1.89e-10 6add:A, 6add:B, 5yge:B, 5yo2:A, 5yo2:B
9 4ab7:H 422 274 0.1557 0.1564 0.2409 1.61e-09 4ab7:D, 3zzf:A, 3zzf:B, 3zzf:C, 3zzf:D, 3zzh:A, 3zzh:B, 3zzh:C, 3zzh:D
10 3wwm:A 269 237 0.1580 0.2491 0.2827 1.68e-08
11 5gcn:A 166 101 0.0613 0.1566 0.2574 4.43e-04 1m1d:A, 1m1d:C, 1pu9:A, 1pua:A, 1q2c:A, 1q2d:A, 1qsn:A, 1qsr:A
12 6ao7:A 153 94 0.0590 0.1634 0.2660 0.087
13 1cm0:A 162 92 0.0566 0.1481 0.2609 0.27 1cm0:B, 4nsq:A, 4nsq:B, 4nsq:C, 4nsq:D
14 3s6h:A 436 266 0.1415 0.1376 0.2256 0.44 4kzt:A, 4kzt:B, 4kzt:X, 4kzt:Y, 3s6g:B, 3s6g:Y, 3s6h:X, 3s6h:B, 3s6h:Y
15 5h86:A 167 95 0.0660 0.1677 0.2947 0.54 8e6o:A, 8e6o:B, 8e6o:C, 8h65:C, 8h65:D, 8h65:E, 8h65:F, 8h65:B, 8h65:A, 8h65:G, 8h65:H, 8h66:E, 8h66:C, 8h66:D, 8h66:F, 8h66:B, 8h66:A, 8h66:G, 8h66:H, 8h6c:C, 8h6c:D, 8h6c:E, 8h6c:F, 8h6c:B, 8h6c:A, 8h6c:G, 8h6c:H, 8h6d:C, 8h6d:D, 8h6d:E, 8h6d:F, 8h6d:B, 8h6d:A, 8h6d:G, 8h6d:H, 5h84:A, 5trl:C, 5trl:D, 5trl:E, 5trl:F, 5trl:B, 5trl:A, 5trl:G, 5trl:H, 1z4r:A
16 3gy9:A 149 104 0.0637 0.1812 0.2596 0.80 3gya:A
17 4mnc:A 305 124 0.0684 0.0951 0.2339 1.1 4mni:A
18 3l86:A 245 212 0.1132 0.1959 0.2264 1.4
19 4jwp:A 165 108 0.0708 0.1818 0.2778 1.4
20 6sl2:A 619 94 0.0708 0.0485 0.3191 1.4 5nl7:A, 6sl3:A
21 8htu:4 206 36 0.0354 0.0728 0.4167 3.0 8htu:8, 7ksq:4, 7kux:4, 7xqp:4, 7xqp:8
22 9c57:G 878 90 0.0637 0.0308 0.3000 3.6
23 5xun:B 171 54 0.0425 0.1053 0.3333 4.0 5xun:A
24 2cnm:A 151 40 0.0330 0.0927 0.3500 5.1 2cnm:B, 2cnm:C, 2cns:A, 2cns:B, 2cns:C, 2cnt:A, 2cnt:B, 2cnt:C, 2cnt:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218