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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
DSCGAEPIHIPGAIQEHGALLVLSAREFSVVQASDNLANYIGVDLPIGAVATEANLPFISVLSAWYSGEESNFRYAWAEK
KLDVSAHRSGTLVILEVEKAGVGESAEKLMGELTSLAKYLNSAPSLEDALFRTAQLVSSISGHDRTLIYDFGLDWSGHVV
AEAGSGALPSYLGLRFPAGDIPPQARQLYTINRLRMIPDVDYKPVPIRPEVNAETGAVLDMSFSQLRSVSPVHLEYMRNM
GTAASMSVSIVVNGALWGLIACHHATPHSVSLAVREACDFAAQLLSMRIAMEQSSQDASRRVELGHIQARLLKGMAAAEK
WVDGLLGGEGEREDLLKQVGADGAALVLGDDYELVGNTPSREQVEELILWLGEREIADVFATDNLAGNYPTAAAYASVAS
GIIAMRVSELHGSWLIWFRPEVIKTVRWGGDPHPRKSFEIWKEQLRNTSFPWSEPELAAARELRGAIIGIVL

The query sequence (length=472) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5hsq:A 488 482 0.9915 0.9590 0.9710 0.0 8co5:A, 5i5l:A, 6r26:A, 6r27:A, 6r27:B, 6r27:C, 6r27:D
2 4r70:A 498 496 0.3877 0.3675 0.3690 1.64e-110 2ool:A, 2ool:B, 4r70:B
3 6bap:A 505 498 0.4110 0.3842 0.3896 1.27e-105 6baf:A, 6bak:A, 6bao:A, 6bao:B, 6bap:B, 6bap:C, 6bay:A, 6bay:B, 6bay:C, 4rq9:A
4 4r6l:A 473 489 0.4089 0.4080 0.3947 4.68e-103 4e04:A, 4e04:B, 4r6l:B, 4s21:A, 4s21:B
5 7jr5:A 482 496 0.4089 0.4004 0.3891 1.22e-93 7jr5:B, 7jri:A, 7jri:B, 6ptq:A, 6ptq:B, 6ptx:A, 6ptx:B, 6pu2:A, 6pu2:B
6 8u8z:A 517 495 0.3835 0.3501 0.3657 2.14e-93 8u4x:A, 8u4x:B, 8u62:B, 8u62:A, 8u63:A, 8u63:B, 8u8z:B
7 2vea:A 500 484 0.3665 0.3460 0.3574 6.83e-92
8 8u64:A 487 483 0.3750 0.3634 0.3665 1.21e-90 8u64:B, 8u65:B, 8u65:A
9 4gw9:A 628 492 0.3623 0.2723 0.3476 1.26e-89 4gw9:B, 4gw9:C, 4gw9:D, 5oy5:A, 5vik:A, 5viq:A, 5viv:A, 4xtq:A
10 6g1y:B 493 496 0.3623 0.3469 0.3448 1.20e-87 6g1y:A, 6g1z:A, 6g1z:B, 6g20:A, 6g20:B
11 8upk:A 739 490 0.3919 0.2503 0.3776 1.82e-87 8uph:A, 8uph:B, 8upk:B, 8upm:A, 8upm:B
12 6pl0:B 608 489 0.3665 0.2845 0.3538 5.45e-85 5akp:A, 5akp:B, 7l59:A, 6ndo:A, 6ndo:B, 6ndp:A, 6ndp:B, 6pl0:A, 5uyr:A, 5uyr:B
13 7l5a:A 477 497 0.3623 0.3585 0.3441 1.26e-80
14 8avw:B 579 485 0.3559 0.2902 0.3464 4.46e-70 8avw:A
15 9eut:A 728 510 0.3729 0.2418 0.3451 5.58e-70 3c2w:A, 3c2w:B, 3c2w:C, 3c2w:D, 3c2w:E, 3c2w:F, 3c2w:G, 3c2w:H, 9eut:B, 9euy:A, 9euy:B, 3g6o:A, 3g6o:B, 3ibr:A, 3ibr:B, 3nhq:A, 3nhq:B, 3nhq:C, 3nhq:D, 3nhq:E, 3nhq:F, 3nhq:G, 3nhq:H, 3nop:C, 3not:C, 3nou:C
16 6fht:B 735 485 0.3602 0.2313 0.3505 1.05e-69 5ajg:A, 8avv:A, 8avv:B, 8avx:A, 8avx:B, 8bor:A, 8bor:B, 8bor:C, 8bor:D, 8c3i:B, 8c3i:A, 5c5k:A, 5c5k:B, 5c5k:C, 5c5k:D, 4cqh:A, 6fht:A, 6ftd:A, 6ftd:B, 4ijg:A, 5k5b:A, 5l8m:A, 5lbr:A, 5mg0:A, 5mg1:A, 5nfx:A, 5nm3:A, 5nm3:B, 5nm3:C, 5nm3:D, 5nwn:A, 5nwn:B, 5nwn:C, 5nwn:D, 4o01:A, 4o01:B, 4o01:C, 4o01:D, 4o0p:A, 4o0p:B, 4o8g:A, 2o9b:A, 2o9c:A, 4q0h:A, 4q0i:A, 4q0j:A, 3s7n:A, 3s7o:A, 3s7p:A, 3s7q:A, 8sgk:A, 8sgk:B, 6t3l:B, 6t3l:A, 6t3u:B, 6t3u:A, 4y3i:A, 4y5f:A, 4z1w:A, 7z9d:A, 7z9e:A, 4zrr:A, 1ztu:A
17 5llw:B 673 499 0.3157 0.2214 0.2986 2.27e-60 5llw:A, 5llx:A, 5llx:B, 5lly:D, 5lly:A, 5lly:C, 5lly:B, 6saw:A, 6saw:B, 6saw:C, 6saw:D, 6saw:E, 6saw:F, 6saw:G, 6saw:H, 6sax:B, 6sax:A
18 6et7:A 646 480 0.3114 0.2276 0.3063 1.59e-58 6et7:B
19 6tl4:A 496 487 0.2945 0.2802 0.2854 3.10e-50
20 8iff:A 868 487 0.3030 0.1647 0.2936 6.33e-50 8f5z:B, 8f5z:A, 8iff:B, 8isj:A, 8isj:B
21 7rzw:B 864 484 0.2797 0.1528 0.2727 3.06e-47 7rzw:A
22 8isk:B 848 480 0.2966 0.1651 0.2917 3.93e-47 8isk:A
23 4our:A 448 485 0.2881 0.3036 0.2804 6.08e-47 4our:B
24 6tby:AAA 320 302 0.1907 0.2812 0.2980 4.31e-32 6tc5:AAA
25 6tc7:BBB 319 318 0.2034 0.3009 0.3019 5.78e-29 6tc7:AAA
26 6ozb:C 193 181 0.1398 0.3420 0.3646 3.59e-26 6ozb:A, 6ozb:B
27 2k2n:A 172 171 0.1314 0.3605 0.3626 5.14e-25 2lb9:A
28 4bwi:A 381 248 0.1525 0.1890 0.2903 3.97e-20 4bwi:B
29 5m85:A 159 135 0.0699 0.2075 0.2444 0.014 5m82:A
30 3w2z:A 178 139 0.0742 0.1966 0.2518 0.025 5zoh:A
31 4fof:A 168 123 0.0614 0.1726 0.2358 0.17 4glq:A, 2m7u:A, 2m7v:A, 6p58:A, 6p58:B, 6pru:A, 6pru:B, 6pry:A, 6pry:B, 6upp:A, 6upp:B, 3vv4:A, 3vv4:B
32 5okn:D 433 74 0.0445 0.0485 0.2838 0.21 4a9c:B, 5okn:C, 5okn:E, 5okn:F, 5okn:H, 6squ:B
33 5okn:G 402 72 0.0339 0.0398 0.2222 0.46 6squ:A
34 6ob8:A 307 155 0.0742 0.1140 0.2258 0.47 6oap:A, 6oap:B, 6oaq:A, 6oaq:B, 6ob8:B
35 6bhn:A 156 139 0.0678 0.2051 0.2302 0.55 6bho:A
36 7yk5:J 139 39 0.0360 0.1223 0.4359 3.3 7yk5:N, 7yk5:L, 7yk5:P
37 6jdc:A 269 118 0.0678 0.1190 0.2712 3.6
38 7dng:A 161 97 0.0593 0.1739 0.2887 4.8 7dnf:A, 7dnf:C, 7dnf:D, 7dnf:F
39 6oa9:D 489 31 0.0360 0.0348 0.5484 5.3 6oaa:E, 6oab:E
40 6opc:B 741 31 0.0360 0.0229 0.5484 5.4 8dar:A, 8dar:B, 8dar:C, 8dar:D, 8dar:E, 8dar:F, 8das:A, 8das:B, 8das:C, 8das:D, 8das:E, 8das:F, 8dat:A, 8dat:B, 8dat:C, 8dat:D, 8dat:E, 8dat:F, 8dau:A, 8dau:B, 8dau:C, 8dau:D, 8dau:E, 8dau:F, 8dav:A, 8dav:B, 8dav:C, 8dav:D, 8dav:E, 8dav:F, 8daw:A, 8daw:B, 8daw:C, 8daw:D, 8daw:E, 8daw:F, 6oa9:A, 6oa9:B, 6oa9:C, 6oa9:E, 6oa9:F, 6oaa:B, 6oaa:C, 6oaa:D, 6oab:D, 6oab:B, 6oab:C, 6oab:A, 6omb:A, 6omb:B, 6omb:C, 6omb:D, 6omb:E, 6opc:A, 6opc:C, 6opc:D, 6opc:E
41 1zfj:A 476 47 0.0297 0.0294 0.2979 5.6
42 2or1:L 63 63 0.0381 0.2857 0.2857 7.2 2or1:R, 1per:L, 1per:R, 1rpe:L, 1rpe:R
43 2qhs:A 210 49 0.0381 0.0857 0.3673 8.6 2qhu:A, 2qhv:A
44 4hs8:H 225 34 0.0212 0.0444 0.2941 8.9
45 6mfb:D 386 94 0.0551 0.0674 0.2766 9.4 6mfb:A, 6mfb:B, 6mfb:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218