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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
DRATKLLTYLADVTVNGHPEAKDRPKPLENAARPVVPYANGNGVKDGTKQLLDTLGPKKFGEWMRNEKRVLLTDTTMRDG
HQSLLATRMRTYDIARIAGTYSHALPNLLSLECWGGATFDVSMRFLTEDPWERLALIREGAPNLLLQMLLRGANGVGYTN
YPDNVVKYFVRQAAKGGIDLFRVFDCLNWVENMRVSMDAIAEENKLCEAAICYTGDILNSARPKYDLKYYTNLAVELEKA
GAHIIAVKDMAGLLKPAAAKVLFKALREATGLPIHFHTHDTSGIAAATVLAAVEAGVDAVDAAMDALSGNTSQPCLGSIV
EALSGSERDPGLDPAWIRRISFYWEAVRNQYAAFESDLKGPASEVYLHEMPGGQFTNLKEQARSLGLETRWHQVAQAYAD
ANQMFGDIVKVTPSSKVVGDMALMMVSQDLTVADVVSPREVSFPESVVSMLKGDLGQPPSGWPEALQKKALKGEKPYTVR
PGSLLKEADLDAERKVIEKKLEREVSDFEFASYLMYPKVFTDFALASDTYGPVSVLPTPAYFYGLADGEELFADIEKGKT
LVIVNQAVSATDSQGMVTVFFELNGQPRRIKVPDRA

The query sequence (length=596) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2qf7:A 1076 597 0.9983 0.5530 0.9966 0.0 3tw6:A
2 3tw6:B 1129 597 0.9966 0.5261 0.9950 0.0 4jx4:A, 4jx4:B, 4jx4:C, 4jx4:D, 4jx5:A, 4jx5:B, 4jx5:C, 4jx5:D, 4jx6:A, 4jx6:B, 4jx6:C, 4jx6:D, 4loc:A, 4loc:B, 4loc:C, 4loc:D, 4m6v:A, 4m6v:B, 4m6v:C, 4m6v:D, 4mfd:A, 4mfd:B, 4mfd:C, 4mfd:D, 4mfe:A, 4mfe:B, 4mfe:C, 4mfe:D, 4mim:A, 4mim:B, 4mim:C, 4mim:D, 3tw6:C, 3tw6:D
3 2qf7:B 1017 597 0.9950 0.5831 0.9933 0.0 3tw7:A, 3tw7:B
4 4qsh:C 1081 596 0.5017 0.2766 0.5017 0.0 4qsh:A, 4qsh:D, 4qsh:B, 4qsk:A, 4qsk:B
5 3bg5:A 1137 597 0.4983 0.2612 0.4975 0.0 3bg5:C, 8gk8:A, 8gk8:B, 3hb9:A, 3hb9:C, 3hbl:A, 3hbl:C, 4hnt:A, 4hnt:C, 4hnu:A, 4hnu:C, 4hnv:A, 4hnv:C
6 4hnv:B 1033 597 0.4983 0.2875 0.4975 0.0 8gk8:D
7 3bg5:B 1074 597 0.4983 0.2765 0.4975 0.0 3bg5:D, 8gk8:C, 3hb9:B, 3hb9:D, 3hbl:B, 3hbl:D, 4hnt:B, 4hnt:D, 4hnu:B, 4hnu:D, 4hnv:D, 3ho8:A, 3ho8:C, 3ho8:B
8 5vyz:C 1083 597 0.4916 0.2705 0.4908 0.0 5vyw:A, 5vyw:B, 5vyw:C, 5vz0:C
9 5vyz:A 1144 598 0.4899 0.2552 0.4883 0.0 5vyw:D, 5vyz:B, 5vyz:D, 5vz0:A, 5vz0:B, 5vz0:D, 7zyy:A, 7zyy:C, 7zyy:B, 7zyy:D, 7zyz:A, 7zz0:A, 7zz1:A, 7zz2:A, 7zz3:A, 7zz3:C, 7zz3:B, 7zz3:D, 7zz4:A, 7zz5:A, 7zz6:D, 7zz6:A, 7zz8:A, 7zz8:C, 7zz8:D, 7zz8:B
10 3ho8:D 934 596 0.4480 0.2859 0.4480 5.45e-173
11 8hwl:A 941 601 0.4732 0.2997 0.4692 2.12e-170 8hwl:B, 8hwl:C, 8hwl:E
12 7wtb:B 1147 601 0.4732 0.2459 0.4692 4.65e-168 3bg3:A, 3bg3:B, 3bg3:C, 3bg3:D, 3bg9:A, 3bg9:B, 3bg9:C, 3bg9:D, 8j7o:A, 8j7o:B, 8j7o:C, 8j7o:E, 7wta:C, 7wta:B, 7wta:D, 7wta:A, 7wtb:C, 7wtb:A, 7wtb:D, 7wtc:C, 7wtc:A, 7wtc:B, 7wtc:D, 7wtd:C, 7wtd:D, 7wte:C, 7wte:D
13 2nx9:B 453 444 0.2785 0.3664 0.3739 1.78e-98 2nx9:A
14 5ks8:D 580 455 0.2987 0.3069 0.3912 2.09e-97
15 5ks8:C 603 455 0.2987 0.2952 0.3912 4.89e-97
16 5ks8:F 482 292 0.2265 0.2801 0.4623 4.96e-79
17 1rqb:A 472 478 0.2785 0.3517 0.3473 2.05e-75 1rqe:A, 1rqh:A, 1rr2:A, 1s3h:A, 1u5j:A
18 6ktq:A 399 99 0.0470 0.0702 0.2828 5.30e-04 6ktq:B
19 3ivt:B 400 106 0.0419 0.0625 0.2358 5.59e-04 3ivs:A, 3ivs:B, 3ivt:A, 3ivu:A, 3ivu:B, 3mi3:A, 3mi3:B
20 6nds:A 305 74 0.0436 0.0852 0.3514 0.002
21 2cw6:A 296 104 0.0487 0.0980 0.2788 0.003 2cw6:B, 2cw6:C, 2cw6:D, 2cw6:E, 2cw6:F, 3mp3:A, 3mp3:B, 3mp3:C, 3mp3:D, 3mp3:E, 3mp3:F, 3mp5:B, 3mp5:C
22 3a9i:A 347 97 0.0436 0.0749 0.2680 0.003 2ztj:A, 2ztk:A, 2zyf:A
23 6e1j:A 409 104 0.0436 0.0636 0.2500 0.040 6e1j:B
24 3bli:A 311 122 0.0520 0.0997 0.2541 0.088 3ble:A, 3blf:A
25 4ov9:A 380 79 0.0369 0.0579 0.2785 0.097 4ov4:A
26 1ydn:A 283 121 0.0537 0.1131 0.2645 0.11 1ydn:B, 1ydn:C, 1ydn:D
27 3rmj:B 308 117 0.0503 0.0974 0.2564 0.52 3rmj:A
28 8ih7:A 340 81 0.0487 0.0853 0.3580 1.0 8ih7:C
29 1kzl:A 202 57 0.0285 0.0842 0.2982 1.5
30 2db3:A 420 64 0.0369 0.0524 0.3438 2.4 2db3:B, 2db3:C, 2db3:D
31 8hvr:I 254 146 0.0654 0.1535 0.2671 2.4 8hvr:J, 8jke:I, 8jke:J, 8k60:I, 8k60:J
32 2qas:A 120 66 0.0268 0.1333 0.2424 2.6
33 3pa1:A 315 175 0.0738 0.1397 0.2514 3.9 5bsx:A, 5bsy:A, 6gw1:A, 6gw1:B, 6gw2:A, 6gw2:B, 6gy9:A, 6gy9:B, 5hza:A, 5hza:B, 5hzb:B, 5hzb:A, 3ony:A, 3ony:B, 3ony:C, 3pa1:B, 3pa2:A, 3pa2:B, 3q38:A, 3q39:A, 3q39:B, 3q3a:B, 3q3a:A, 3ry8:A, 8y6c:B, 8y6c:A, 8y6d:B, 8y6d:A, 4z4r:A, 4z4r:B, 4z4s:A, 4z4s:B, 4z4t:A, 4z4t:B, 4z4u:A, 4z4u:B, 4z4v:A, 4z4v:B, 4z4w:A, 4z4w:B, 4z4y:A, 4z4z:A, 4z4z:B
34 5ae6:B 767 96 0.0419 0.0326 0.2604 5.0 5a7m:A, 5a7m:B, 5ae6:A
35 3n75:A 711 26 0.0235 0.0197 0.5385 6.1 3n75:D, 3n75:B, 3n75:E, 3n75:C, 6q7l:A, 6q7l:F, 6q7l:B, 6q7l:C, 6q7l:D, 6q7l:J, 6q7l:E, 6q7l:H, 6q7l:G, 6q7l:I, 6q7l:K, 6q7l:R, 6q7l:L, 6q7l:Q, 6q7l:M, 6q7l:P, 6q7l:N, 6q7l:T, 6q7l:O, 6q7l:S, 6q7m:A, 6q7m:F, 6q7m:B, 6q7m:C, 6q7m:D, 6q7m:J, 6q7m:E, 6q7m:H, 6q7m:G, 6q7m:I, 6q7m:K, 6q7m:R, 6q7m:L, 6q7m:Q, 6q7m:M, 6q7m:P, 6q7m:N, 6q7m:O, 6q7m:S, 6q7m:T

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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