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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
DQPRPAFSAIRRNPPMGGNVVIFDTVITNQEEPYQNHSGRFVCTVPGYYYFTFQVLSQWEICLSIVSSSRGQVRRSLGFC
DTTNKGLFQVVSGGMVLQLQQGDQVWVEKDPKKGHIYQGSEADSVFSGFLIFPSAKFQSVFTVTRQTHQPPAPNSLIRFN
AVLTNPQGDYDTSTGKFTCKVPGLYYFVYHASHTANLCVLLYRSGVKVVTFCGHTSKTNQVNSGGVLLRLQVGEEVWLAV
NDYYDMVGIQGSDSVFSGFLLFPDGSAKATQKIAFSATRTINVPLRRDQTIRFDHVITNMNNNYEPRSGKFTCKVPGLYY
FTYHASSRGNLCVNLMRGRERAQKVVTFCDYAYNTFQVTTGGMVLKLEQGENVFLQATDKNSLLGMEGANSIFSGFLLFP
DM

The query sequence (length=402) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5hkj:A 402 402 1.0000 1.0000 1.0000 0.0 5hzf:A, 2jg8:B, 2jg8:C, 2jg8:D, 2jg8:E, 2jg9:B, 2jg9:E, 1pk6:B, 2wnu:F, 2wnv:B, 2wnv:C, 2wnv:D, 2wnv:E
2 4dou:A 399 399 0.3234 0.3258 0.3258 1.61e-57
3 4dou:A 399 275 0.2438 0.2456 0.3564 1.62e-40
4 5kca:A 807 419 0.3060 0.1524 0.2936 7.36e-38 5kc8:A
5 6u66:B 142 134 0.1343 0.3803 0.4030 7.72e-21 1c3h:D, 1c3h:E, 1c3h:F, 6u66:A, 6u66:C
6 6u66:B 142 141 0.1169 0.3310 0.3333 1.07e-15 1c3h:D, 1c3h:E, 1c3h:F, 6u66:A, 6u66:C
7 6u66:B 142 115 0.0796 0.2254 0.2783 4.02e-11 1c3h:D, 1c3h:E, 1c3h:F, 6u66:A, 6u66:C
8 4qql:C 131 143 0.1294 0.3969 0.3636 3.03e-19 4qql:A, 4qql:B, 4qql:D, 4qql:F, 4qql:E, 4qql:G, 4qql:H, 4qql:I
9 4qql:C 131 138 0.1144 0.3511 0.3333 3.29e-14 4qql:A, 4qql:B, 4qql:D, 4qql:F, 4qql:E, 4qql:G, 4qql:H, 4qql:I
10 4qql:C 131 118 0.0920 0.2824 0.3136 1.25e-12 4qql:A, 4qql:B, 4qql:D, 4qql:F, 4qql:E, 4qql:G, 4qql:H, 4qql:I
11 4d7y:A 131 138 0.1169 0.3588 0.3406 2.07e-18
12 4d7y:A 131 138 0.1269 0.3893 0.3696 1.21e-16
13 4d7y:A 131 118 0.0920 0.2824 0.3136 4.47e-12
14 1o91:C 131 130 0.1169 0.3588 0.3615 2.18e-18
15 1o91:C 131 132 0.1045 0.3206 0.3182 2.42e-12
16 1o91:C 131 128 0.0995 0.3053 0.3125 1.39e-10
17 1gr3:A 132 113 0.0945 0.2879 0.3363 9.81e-16
18 1gr3:A 132 118 0.1070 0.3258 0.3644 3.51e-13
19 1gr3:A 132 133 0.0945 0.2879 0.2857 1.37e-11
20 8a5a:U 690 74 0.0498 0.0290 0.2703 1.5 8a5o:U, 4am7:A, 4am7:B
21 4u03:A 389 30 0.0249 0.0257 0.3333 3.6 4txy:A, 4txz:A, 4ty0:A, 4u03:B, 4u0m:A, 4u0m:B, 4u0n:A, 4u0n:B, 4xj4:A
22 5cqx:B 116 29 0.0299 0.1034 0.4138 4.4 5cqx:A, 5cqy:A, 5cqy:B, 5cr2:A, 5cr2:B, 5cr2:C
23 5nxb:A 644 62 0.0448 0.0280 0.2903 5.2 4ccc:A, 4ccd:A, 4cce:A, 5nxb:B, 4ufh:A, 4ufi:A, 4ufj:A, 4ufk:A, 4ufl:A, 4ufm:A, 6y6s:A, 6y6t:A, 3zr5:A, 3zr6:A
24 8b6j:D 295 64 0.0423 0.0576 0.2656 7.6 8b6j:d, 8bqs:D, 8bqs:d, 8gym:qD, 8gym:qd, 8gym:Qd, 8gym:QD, 8gzu:qD, 8gzu:qd, 8gzu:QD, 8gzu:Qd, 7tgh:3D, 7tgh:3d

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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