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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
DQKKHRKKNSGPKAAKKKKRLLQDEEDARKRNPKAFAVQSAVRMARSFHRTQDLKTKKHHIPVVDRTPLEPPPIVVVVMG
PPKVGKSTLIQCLIRNFTRQKLTEIRGPVTIVSGKKRRLTIIECGCDINMMIDLAKVADLVLMLIDASFGFEMETFEFLN
ICQVHGFPKIMGVLTHLDSFKHNKQLKKTKKRLKHRFWTEVYPGAKLFYLSGMVHGEYQNQEIHNLGRFITVMKFRPLTW
QTSHPYILADRMEDLTNPEDIRTNIKCDRKVSLYGYLRGAHLKNKSQIHMPGVGDFAVSDISFLPDPCALPEQQKKRCLN
EKEKLVYAPLSGVGGRQQQAAPNLRKLIYGHKADSLDCSRFLVEAPHDWDLEEVMNSIRDCFVTESTYFDDLKGEMQKQA
QLNRAEFEDQDDEARVQYEGFRPGMYVRIEIENVPCEFVQNFDPHYPIILGGLGNSEGNVGYVQMRLKKHRWYKKILKSR
DPIIFSVGWRRFQTIPLYYIEDHNGRQRLLKYTPQHMHCGAAFWGPITPQGTGFLAIQSVSGIMPDFRIAATGVVLDLDK
SIKIVKKLKLTGFPYKIFKNTSFIKGMFNSALEVAKFEGAVIRTVSGIRGQIKKALRAPEGAFRASFEDKLLMSDIVFMR
TWYPVSIPAFYNPVTSLLKPVGEKDTWSGMRTTGQLRLAHGVRLKANKDSLYKPILRQKKHFNSLHIPKALQKALPFKNK
PKTQAKAGKVPKDRRRPAVIREPHERKILALLDALSTVHSQKMKKAKEQRHLHNKEHFRAKQKEEEEKLKRQKDLRKKLF
RIQ

The query sequence (length=803) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7mqa:SI 803 803 1.0000 1.0000 1.0000 0.0
2 7mq8:SI 844 468 0.5791 0.5509 0.9936 0.0 7mq9:SI
3 7mq8:SI 844 296 0.3686 0.3507 1.0000 0.0 7mq9:SI
4 7ajt:CL 781 790 0.4932 0.5070 0.5013 0.0 7d5s:RJ, 6zqa:CL, 6zqb:CL, 6zqc:CL
5 7aju:CL 808 836 0.5006 0.4975 0.4809 0.0 6zqd:CL, 6zqe:CL, 6zqf:CL, 6zqg:CL
6 7suk:SI 802 815 0.4907 0.4913 0.4834 0.0 7d63:RJ, 6ke6:RJ, 6lqp:RJ, 6lqq:RJ, 6lqr:RJ, 6lqu:RJ, 6lqv:RJ, 5wlc:SI
7 7d4i:RJ 738 771 0.4770 0.5190 0.4968 0.0 7d5t:RJ, 6lqs:RJ, 6lqt:RJ
8 7wtl:CL 610 657 0.4284 0.5639 0.5236 0.0 5wyj:B1, 5wyk:B1
9 6rxt:CI 822 424 0.2590 0.2530 0.4906 4.16e-132 6rxu:CI, 6rxv:CI, 6rxx:CI, 6rxy:CI, 6rxz:CI
10 6rxt:CI 822 296 0.1893 0.1849 0.5135 5.37e-99 6rxu:CI, 6rxv:CI, 6rxx:CI, 6rxy:CI, 6rxz:CI
11 5oql:Z 639 442 0.2441 0.3067 0.4434 1.57e-114
12 5oql:Z 639 243 0.1594 0.2003 0.5267 8.53e-80
13 7wtt:u 642 646 0.1930 0.2414 0.2399 4.13e-26 6g18:u, 6g4s:u, 6g4w:u, 6g51:u, 7wts:u, 7wtu:u, 7wtv:u, 7wtw:u, 7wtx:u, 7wtz:u, 7wu0:u, 6zmt:u, 6zn5:u
14 8c00:t 619 205 0.0672 0.0872 0.2634 1.54e-09 8c01:t, 6rbd:k, 7wtr:CC
15 8c00:t 619 177 0.0448 0.0582 0.2034 1.63e-04 8c01:t, 6rbd:k, 7wtr:CC
16 8cbj:k 670 205 0.0672 0.0806 0.2634 1.70e-09 6fai:k, 6y7c:t
17 8cbj:k 670 177 0.0436 0.0522 0.1977 8.09e-05 6fai:k, 6y7c:t
18 7wtp:CC 661 205 0.0672 0.0817 0.2634 1.84e-09 6eml:t, 6wdr:k, 7wtq:CC
19 7wtp:CC 661 177 0.0436 0.0530 0.1977 9.56e-05 6eml:t, 6wdr:k, 7wtq:CC
20 3geh:A 442 79 0.0299 0.0543 0.3038 0.18
21 5mej:A 499 69 0.0224 0.0361 0.2609 0.30 5e9n:A, 5mew:A, 5mhu:A, 5mhv:A, 5mhw:A, 5mhx:A, 5mhy:A, 5mhz:A, 5mi1:A, 5mi2:A, 5mia:A, 5mib:A, 5mic:A, 5mid:A, 5mie:A, 5mig:A, 6rgh:A, 6rgp:A, 6rhh:A, 6rhi:A, 6rho:A, 6rhp:A, 6rhr:A, 6rhu:A, 6rhx:A, 6ri0:A, 6ri2:A, 6ri4:A, 6ri6:A, 6ri8:A, 6rii:A, 6rik:A, 6ril:A
22 6yxy:EQ 471 37 0.0174 0.0297 0.3784 0.52
23 7zjw:E 519 97 0.0286 0.0443 0.2371 0.89 5izl:A, 5izl:B
24 6gyf:B 366 85 0.0324 0.0710 0.3059 1.1 6gye:A, 6gye:B, 6gyf:A, 6gzo:A, 6gzo:B
25 5izm:B 495 90 0.0299 0.0485 0.2667 1.3 5izk:A, 5izm:A
26 3qu1:A 168 121 0.0361 0.1726 0.2397 1.4 3qu1:B
27 6s5f:A 188 57 0.0262 0.1117 0.3684 1.7
28 3j8g:X 418 82 0.0336 0.0646 0.3293 1.8
29 7pxc:E 483 36 0.0199 0.0331 0.4444 2.4 7px9:A, 7px9:B, 7px9:C, 7px9:E, 7px9:F, 7pxb:A, 7pxb:B, 7pxb:C, 7pxb:E, 7pxb:F, 7pxc:B, 7pxc:C, 7pxc:F, 7pxc:A, 7pxd:B, 7pxd:C, 7pxd:E, 7pxd:F, 7pxd:A
30 1mky:A 407 92 0.0349 0.0688 0.3043 2.4
31 7sqc:1C 1700 43 0.0187 0.0088 0.3488 2.4 7sqc:1D
32 7sqc:1B 1660 43 0.0187 0.0090 0.3488 2.5
33 5dn8:A 405 88 0.0324 0.0642 0.2955 2.6
34 6hyp:A 2272 99 0.0361 0.0128 0.2929 2.7
35 2e87:A 356 33 0.0224 0.0506 0.5455 3.5
36 1zny:A 183 19 0.0149 0.0656 0.6316 4.2 1znx:A, 1znz:A
37 2dyk:A 150 117 0.0399 0.2133 0.2735 4.8 2dyk:B
38 2bbw:A 220 27 0.0149 0.0545 0.4444 5.4 2bbw:B
39 2lkd:A 178 111 0.0361 0.1629 0.2613 6.1
40 3c41:J 242 19 0.0149 0.0496 0.6316 6.9 3c41:K, 3c4j:A, 3c4j:B, 2olj:A, 2olj:B, 2olk:A, 2olk:B, 2olk:C, 2olk:D, 2q0h:A, 2q0h:B
41 2m7b:A 77 32 0.0149 0.1558 0.3750 8.6
42 7cte:D 406 127 0.0423 0.0837 0.2677 8.9 7ctf:D, 7ctg:D, 7jpo:D, 7jpp:D, 7jpq:D, 7jpr:D, 7jps:D, 5uj7:C, 5uj7:D, 5ujm:D
43 6yoz:AAA 400 55 0.0224 0.0450 0.3273 9.4 1ojj:A, 1ojj:B, 1ojk:A, 1ojk:B, 6yoz:BBB
44 8s4t:A 136 41 0.0187 0.1103 0.3659 9.6 8s4t:B, 8s4t:C
45 6yxy:EM 330 64 0.0274 0.0667 0.3438 9.7

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218