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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
DPTNQKACLSLLEDLTTNVKQIQDSVLEAILSRNAQTEYLRGFLNGQVDKQNFKKNVPVVTYEDIRSYIDRIANGEPSDL
ICDRPISVLLTPKLIPLTTEDLEQRISFSSLYAPLLYKHIDGLSEGKSLIFYFVTRESKTANGLMVRTMVTSFLKSDSLQ
VSPHAITTCADTTQSMYCQLLCGLLERDNVARLGAPFASSFLKVIKFLEDHWPELCSNIRTGRLSDWITDATCTSGIGKF
LTAPNPELASLIEQECSKTSWEAILKRLWPKAKCIESIITGTMAQYIPLLEFYSGGLPLTSSFYGSSECFMGVNFNPLCK
PSDVSYTIIPCMGYFEFLEVPVVVDLVDVKIGHDYEPVVTTFSGLYRYRVGDVLRATGFYNNAPHFCFVGRQKVVLSIDM
DKTYEDDLLKAVTNAKLLLEPHDLMLMDFTSRVDSSSFPGHYVIYWELGSKVKFEPNRDVMEECCFTVEESLDAVYRKGR
KNDKNIGPLEIKVVKPGAFDELMNFFLSRGSSVSQYKTPRSVTNEEALKILEANVISEFLSRKIPSW

The query sequence (length=547) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6e1q:A 569 563 0.9982 0.9596 0.9698 0.0 6avh:A, 6avh:C, 6avh:D
2 6avh:B 541 546 0.9872 0.9982 0.9890 0.0
3 7vka:A 595 581 0.5229 0.4807 0.4923 0.0 5kod:A, 5kod:B, 5kod:C, 7vka:B
4 5kod:D 566 564 0.5174 0.5000 0.5018 0.0
5 4epm:A 554 553 0.4973 0.4910 0.4919 0.0 4eq4:A, 4eq4:B, 4eql:A, 4eql:B, 4l39:A, 4l39:B, 6oms:A, 6oms:B
6 7dk8:A 558 559 0.4808 0.4713 0.4705 0.0
7 4b2g:B 572 575 0.4826 0.4615 0.4591 1.86e-178 4b2g:A
8 4ewv:B 492 540 0.4479 0.4980 0.4537 3.31e-162 4ewv:A
9 5ech:A 569 562 0.3693 0.3550 0.3594 5.25e-113 5ech:D, 5eci:A, 5eci:D, 5eck:A, 5eck:D, 5ecl:A, 5ecl:D, 5ecm:A, 5ecm:D, 5ecn:A, 5ecn:D, 5eco:A, 5eco:D, 5ecp:A, 5ecp:D, 5ecq:A, 5ecq:D, 5ecr:A, 5ecr:D, 4epl:A, 5gzz:A
10 7c3o:A 316 44 0.0293 0.0506 0.3636 1.7
11 2wmg:A 553 117 0.0512 0.0506 0.2393 4.1 2wmh:A
12 4lt6:A 467 49 0.0256 0.0300 0.2857 5.9 4lt6:B
13 5kdi:A 211 65 0.0329 0.0853 0.2769 6.1 5kdi:B
14 3s6t:A 575 54 0.0274 0.0261 0.2778 6.7 3nsn:A, 3ozo:A, 3ozp:A, 3vtr:A, 3wmb:A, 3wmc:A, 5y0v:A, 5y1b:A
15 5hgc:A 373 115 0.0512 0.0751 0.2435 8.2

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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