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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
DPRLYFENRSKFIQDQKDKGINPYPHKFERTISIPEFIEKYKDLGNGEHLEDTILNITGRIMRVSKLRFFDLVGDGEKIQ
VLANYSFHNHEKGNFAECYDKIRRGDIVGIVGFPGKSKKGELSIFPKETILLSACLHMLPMKEIRYRQRYLDLLINESSR
HTFVTRTKIINFLRNFLNERGFFEVETPMMNLIAGGANARPFITHHNDLDLDLYLRIATELPLKMLIVGGIDKVYEIGKV
FRNEGIDNTHNPEFTSCEFYWAYADYNDLIKWSEDFFSQLVYHLFGTYKISYNKDGPENQPIEIDFTPPYPKVSIVEEIE
KVTNTILEQPFDSNETIEKMINIIKEHKIELPNPPTAAKLLDQLASHFIENKYNDKPFFIVEHPQIMSPLAKYHRTKPGL
TERLEMFICGKEVLNAYTELNDPFKQKECFKLQQKDRQLDSAFCTSLEYGLPPTGGLGLGIDRITMFLTNKNSIKDVILF
PTMRP

The query sequence (length=485) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6agt:B 506 503 1.0000 0.9585 0.9642 0.0 6agt:A, 6agt:C, 6agt:D, 7bt5:A, 7bt5:B, 6hcu:A, 6hcu:B, 6hcv:A, 6hcv:B, 8k9s:A, 8k9s:B, 8k9u:A, 8k9u:B, 8k9v:A, 8k9v:B, 8k9w:A, 8k9w:B, 8k9x:A, 8k9x:B, 6ka6:A, 6ka6:B, 6ka6:C, 6ka6:D, 6kab:A, 6kab:B, 6kab:C, 6kab:D, 6kbf:A, 6kbf:B, 6kcn:A, 6kcn:B, 6kcn:C, 6kcn:D, 6kct:A, 6kct:B, 6kct:C, 6kct:D, 6l3y:B, 6l3y:A, 6l4q:B, 6l4q:A, 6m0t:A, 6m0t:B, 6m0t:C, 6m0t:D, 4pg3:A, 4pg3:B, 4pg3:C, 4pg3:D, 4ycv:A, 4ycv:B, 4ycv:C, 4ycv:D, 5zh2:B, 5zh3:A, 5zh3:B, 5zh4:A, 5zh4:B, 5zh5:A, 5zh5:B
2 5zh2:A 464 489 0.9423 0.9849 0.9346 0.0
3 6bni:A 502 500 0.5567 0.5378 0.5400 0.0 6bni:B, 6c86:A, 6c86:B, 5eln:A, 5eln:B, 5eln:C, 5eln:D, 5elo:A, 5elo:B, 5elo:C, 5elo:D, 6hcw:A, 6hcw:B, 7zog:A, 7zog:B, 7zog:C, 7zog:D
4 6chd:A 506 506 0.5588 0.5356 0.5356 0.0 3bju:A, 3bju:B, 3bju:C, 3bju:D, 6chd:B, 4dpg:A, 4dpg:B, 4dpg:C, 4dpg:D, 4dpg:E, 4dpg:F, 4dpg:G, 4dpg:H, 7ea9:A, 7ea9:B, 7ea9:C, 7ea9:D, 6ild:A, 6ild:B, 6ilh:A, 6ilh:B, 4ycu:A, 4ycu:B, 4ycw:A, 4ycw:B, 4ycw:E, 4ycw:F
5 5hgq:B 482 493 0.5402 0.5436 0.5314 0.0 5hgq:A, 5hgq:D, 5hgq:C
6 7f6w:A 506 509 0.5175 0.4960 0.4931 3.01e-168
7 4up7:A 529 503 0.4660 0.4272 0.4493 2.03e-149 4up9:A, 4upa:A
8 3a74:A 484 482 0.4289 0.4298 0.4315 6.92e-122 3a74:B, 3a74:C, 3a74:D, 3e9h:A, 3e9h:B, 3e9h:C, 3e9h:D, 3e9i:A, 3e9i:B, 3e9i:C, 3e9i:D
9 1e1t:A 485 497 0.4247 0.4247 0.4145 3.29e-117 1e1o:A, 1e22:A, 1e24:A, 1lyl:A, 1lyl:B, 1lyl:C, 5yzx:A, 5yzx:B, 5yzx:C
10 1bbu:A 486 498 0.4227 0.4218 0.4116 2.39e-110
11 4ex5:A 486 497 0.3959 0.3951 0.3863 1.14e-100 4ex5:B
12 6wbd:B 485 501 0.3794 0.3794 0.3673 2.86e-97 6wbd:A
13 6aqg:C 490 500 0.3629 0.3592 0.3520 7.51e-96 6aqg:A, 6aqg:B, 6aqg:D, 5vl1:A, 5vl1:B, 5vl1:C, 5vl1:D
14 6nrz:A 517 515 0.3773 0.3540 0.3553 6.68e-94 6nrz:B, 6ns0:A, 6ns0:B, 6o3f:A, 6o3f:B
15 6aqh:B 490 505 0.3526 0.3490 0.3386 1.65e-83 6aqh:A, 6aqh:C, 6aqh:D
16 7qh8:A 471 498 0.3505 0.3609 0.3414 2.51e-79 7qhn:A, 7qi8:A
17 3a5z:C 324 336 0.1753 0.2623 0.2530 8.44e-25 3a5y:B, 3a5y:C, 3a5y:D, 3a5z:A, 3a5z:E, 3a5z:G, 3g1z:A, 3g1z:B
18 3a5y:A 297 336 0.1670 0.2727 0.2411 1.05e-23
19 1b8a:A 438 411 0.2062 0.2283 0.2433 4.58e-18 1b8a:B, 3nel:A, 3nem:A, 3nem:B
20 4o2d:B 515 381 0.1897 0.1786 0.2415 5.34e-14
21 1asy:A 490 348 0.1670 0.1653 0.2328 2.36e-12 1asy:B, 1asz:A, 1asz:B
22 4wj3:M 589 140 0.0845 0.0696 0.2929 3.65e-11 4wj3:N, 4wj3:O, 4wj3:P, 4wj4:A
23 4wj3:M 589 87 0.0557 0.0458 0.3103 1.05e-07 4wj3:N, 4wj3:O, 4wj3:P, 4wj4:A
24 1c0a:A 585 174 0.0969 0.0803 0.2701 4.71e-10 1il2:A, 1il2:B
25 1c0a:A 585 81 0.0577 0.0479 0.3457 9.69e-08 1il2:A, 1il2:B
26 6sjc:B 581 157 0.0784 0.0654 0.2420 7.59e-10 7ap4:A, 7ap4:B, 1efw:A, 1efw:B, 1g51:A, 1g51:B, 6hhv:A, 6hhv:B, 6hhw:A, 6hhw:B, 6hhx:A, 6hhx:B, 6sjc:A
27 6sjc:B 581 109 0.0742 0.0620 0.3303 1.62e-09 7ap4:A, 7ap4:B, 1efw:A, 1efw:B, 1g51:A, 1g51:B, 6hhv:A, 6hhv:B, 6hhw:A, 6hhw:B, 6hhx:A, 6hhx:B, 6sjc:A
28 5w25:A 583 179 0.0990 0.0823 0.2682 2.36e-09 5w25:B
29 5w25:A 583 86 0.0515 0.0429 0.2907 7.45e-04 5w25:B
30 4o2d:A 580 181 0.0990 0.0828 0.2652 1.30e-08 4rmf:A
31 4o2d:A 580 36 0.0371 0.0310 0.5000 1.06e-04 4rmf:A
32 3kfu:C 377 373 0.1505 0.1936 0.1957 1.35e-07 3kfu:A, 3kfu:D, 3kfu:B
33 2xgt:B 433 158 0.0887 0.0993 0.2722 4.42e-06 2xgt:A, 2xti:A, 2xti:B
34 3m4p:A 435 335 0.1299 0.1448 0.1881 4.01e-05 3m4p:B, 3m4p:C, 3m4p:D
35 8tc8:A 435 354 0.1464 0.1632 0.2006 1.19e-04 8h53:A, 8h53:B, 8h53:C, 8h53:D, 8tc8:B, 8tc8:C, 8tc8:D, 8tc9:A, 8tc9:B, 8tc9:C, 8tc9:D
36 1x54:A 434 351 0.1629 0.1820 0.2251 1.54e-04 1x55:A
37 3p8v:A 294 334 0.1443 0.2381 0.2096 0.012 3p8v:B, 3p8y:A, 3p8y:B, 3reu:A, 3reu:B, 3rex:A, 3rex:B, 3rl6:A, 3rl6:B
38 7u0r:B 278 116 0.0680 0.1187 0.2845 0.26 8c49:A, 8c49:B, 8dqg:D, 8dqg:A, 8dqh:D, 8dqh:A, 8dqi:D, 8dqi:A, 8dqj:D, 7u0r:A
39 8ci0:AAA 666 195 0.0907 0.0661 0.2256 1.2 8ci0:BBB, 8ci0:CCC, 1itz:A, 1itz:B, 1itz:C
40 7by6:A 299 26 0.0268 0.0435 0.5000 1.9
41 7dpi:C 292 26 0.0268 0.0445 0.5000 2.4 7dpi:A
42 6ha8:V 541 91 0.0454 0.0407 0.2418 2.4
43 3mbo:E 375 84 0.0454 0.0587 0.2619 2.5 3mbo:A, 3mbo:C, 3mbo:H
44 3l4g:C 508 55 0.0371 0.0354 0.3273 3.3 3l4g:A, 3l4g:E, 3l4g:G, 3l4g:I, 3l4g:K, 3l4g:M, 3l4g:O
45 5mgu:A 407 44 0.0309 0.0369 0.3409 4.3 3cmq:A, 3hfv:A, 5mgh:A, 5mgw:A, 8p8x:A, 3teg:A, 3tup:A
46 6z1p:BS 433 130 0.0660 0.0739 0.2462 4.4
47 7d08:B 263 155 0.0701 0.1293 0.2194 6.1 7d08:E, 7d09:B, 7d09:E, 7d0a:B, 7d0a:E, 6z5u:K, 6z5u:L
48 7k5b:B 4524 171 0.0784 0.0084 0.2222 6.6 8bx8:B, 7k58:B, 7kek:B
49 5hb3:C 709 27 0.0289 0.0197 0.5185 8.3 5hb3:A, 7tbi:D1, 7tbi:D2, 7tbi:D3, 7tbi:D4
50 3m49:A 665 84 0.0474 0.0346 0.2738 9.5 3hyl:A, 3hyl:B, 3m49:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218