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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
DNLFVHRDTPEDNPNIPFEFTAENKKRVEAILSIYPEGHKRGAMIPLLDLAQRQYGWLPISAMHKVAEILQLPNMRVYEV
ATFYTMFMRKPTGKYHIQVCTTTPCWLRGSDDILETCKKQLGIGVGDTTKDRKFTISEVECLGACVNAPMVAINDDYYED
LTSKDMQDILNDLKADKISPPGPRNGRFASEPKGEPTSLSEEPKGPGFGLQAGL

The query sequence (length=214) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8b9z:E 214 214 1.0000 1.0000 1.0000 2.07e-163 8ba0:E, 8esw:V2, 8esz:V2
2 7v2c:O 217 212 0.7243 0.7143 0.7311 2.79e-116 7ak5:E, 7ak6:E, 7b93:E, 8c2s:E, 8ca3:E, 8ca4:E, 8ca5:E, 7dgq:9, 7dgr:9, 7dgs:9, 7dgz:9, 7dh0:9, 7dkf:92, 6g2j:E, 6g72:E, 5gpn:d, 8iao:E, 8iap:E, 8ib4:E, 8ib5:E, 8ib9:E, 8iba:E, 8ibd:E, 8ibe:E, 8ic2:E, 8ic3:E, 5lc5:E, 5ldw:E, 5ldx:E, 5lnk:2, 5o31:E, 8olt:E, 8om1:E, 7psa:E, 8pw5:2, 8pw6:2, 8pw7:2, 8q0a:E, 8q0f:E, 8q0j:E, 8q0m:E, 8q0o:E, 8q0q:E, 8q1p:E, 8q1u:E, 8q1y:E, 8q25:E, 8q45:E, 8q46:E, 8q47:E, 8q48:E, 8q49:E, 8q4a:E, 6q9d:V2, 6qa9:V2, 6qbx:V2, 6qc2:V2, 6qc3:V2, 6qc4:V2, 6qc5:V2, 6qc6:V2, 6qc7:V2, 6qc8:V2, 6qc9:V2, 6qca:V2, 6qcf:V2, 7qsd:E, 7qsk:E, 7qsl:E, 7qsm:E, 7qsn:E, 7qso:E, 7r41:E, 7r42:E, 7r43:E, 7r44:E, 7r45:E, 7r46:E, 7r47:E, 7r48:E, 7r4c:E, 7r4d:E, 7r4f:E, 7r4g:E, 8rgp:2, 8rgq:2, 8rgr:2, 8rgt:2, 8ud1:1E, 8ueo:1E, 8uep:1E, 8ueq:1E, 8uer:1E, 8ues:1E, 8uet:1E, 8ueu:1E, 8uev:1E, 8uew:1E, 8uex:1E, 8uey:1E, 8uez:1E, 8ugh:1E, 8ugi:1E, 8ugj:1E, 8ugn:1E, 8ugn:5E, 8ugr:1E, 8ugr:5E, 7v2d:O, 7v2e:O, 7v2f:O, 7v2h:O, 7v2k:O, 7v2r:O, 7v30:O, 7v31:O, 7v32:O, 7v33:O, 7v3m:O, 7vb7:O, 7vbn:O, 7vbz:O, 7vwj:O, 7vxp:O, 7vxu:O, 7vy8:O, 7vya:O, 7vyf:O, 7vyh:O, 7vyn:O, 7vz1:O, 7vzv:O, 7vzw:O, 7w00:O, 7w0h:O, 7w0r:O, 7w0y:O, 7w1o:O, 7w1p:O, 7w1t:O, 7w1u:O, 7w1v:O, 7w1z:O, 7w20:O, 7w2k:O, 7w2l:O, 7w2r:O, 7w2u:O, 7w2y:O, 7w31:O, 7w32:O, 7w35:O, 7w4c:O, 7w4d:O, 7w4e:O, 7w4f:O, 7w4g:O, 7w4j:O, 7w4k:O, 7w4l:O, 7w4m:O, 7w4n:O, 7w4q:O, 5xtb:O, 5xtd:O, 5xth:O, 5xti:O, 5xti:BO, 7zd6:2, 7zdh:2, 7zdj:2, 7zdm:2, 7zdp:2, 7zeb:2, 6zk9:2, 6zkc:2, 6zkd:2, 6zke:2, 6zkf:2, 6zkg:2, 6zkh:2, 6zki:2, 6zkj:2, 6zkk:2, 6zkl:2, 6zkm:2, 6zkn:2, 6zko:2, 6zkp:2, 6zkq:2, 6zkr:2, 6zks:2, 6zkt:2, 6zku:2, 6zkv:2, 6zr2:E, 6ztq:E
3 5gup:E 197 172 0.5841 0.6345 0.7267 7.34e-92
4 7zmb:H 221 213 0.5654 0.5475 0.5681 4.91e-82 7zm7:H, 7zmg:H
5 7b0n:E 216 212 0.5561 0.5509 0.5613 1.28e-81 6gcs:H, 7o6y:H, 7o71:H, 6rfq:H, 6rfr:H, 6rfs:H, 6y79:H, 6yj4:E
6 8e73:V2 222 216 0.4907 0.4730 0.4861 2.54e-67 6x89:V2
7 7a23:B 219 218 0.4579 0.4475 0.4495 5.07e-64 7a24:B, 7aqr:E, 7ar7:E, 7ar8:E, 7arb:E, 8bed:E, 8bpx:E, 8bq5:E, 8bq6:E
8 7arc:E 235 205 0.4673 0.4255 0.4878 2.17e-63 7ard:E
9 8b6f:AI 231 187 0.4206 0.3896 0.4813 6.37e-60 8bqs:AI, 8gym:v2, 8gym:V2, 8gzu:v2, 8gzu:V2, 7tgh:V2
10 8iuf:V2 225 200 0.4346 0.4133 0.4650 5.51e-58 8j9h:V2, 8j9i:V2, 8j9j:V2
11 8qby:E 236 189 0.3785 0.3432 0.4286 7.08e-53
12 8a6t:C 151 147 0.2804 0.3974 0.4082 1.82e-35 8a6t:F, 8bew:C, 8bew:F
13 8e9g:E 233 174 0.3084 0.2833 0.3793 3.31e-34 8e9h:E, 8e9i:E
14 7t2r:C 152 151 0.2850 0.4013 0.4040 2.07e-33 7t2r:H
15 3iam:2 179 159 0.2617 0.3128 0.3522 1.08e-32 2fug:2, 2fug:B, 2fug:K, 2fug:T, 4hea:2, 4hea:C, 6i0d:2, 6i0d:C, 6i1p:2, 6i1p:C, 3i9v:2, 3i9v:B, 3iam:B, 3ias:2, 3ias:B, 3ias:K, 3ias:T, 3m9s:2, 3m9s:B, 6q8o:2, 6q8o:C, 6q8w:2, 6q8w:C, 6q8x:2, 6q8x:C, 6y11:2, 6y11:C, 2ybb:2, 6ziy:2, 6zjl:2, 6zjn:2, 6zjy:2
16 7p5h:C 156 149 0.2664 0.3654 0.3826 8.60e-32 7p5h:F, 7p5h:c, 7p5h:f, 7p8n:c, 7p8n:C, 7p91:c, 7p91:C, 7p92:C
17 8a5e:C 156 150 0.2710 0.3718 0.3867 6.04e-31 7q4v:C, 7q4v:G, 7q4w:C, 7q4w:G
18 9fdk:C 160 154 0.2664 0.3563 0.3701 4.38e-30 9fdj:A, 9fdj:C, 9fdk:A, 9fdv:A, 9fdv:C, 9fe0:A, 9fe0:C, 9fe5:A, 9fe5:C, 9fe7:A, 9fe7:C, 9fe8:A, 9fe8:C, 9fea:A, 9fea:C, 9fif:A, 9fif:C, 9fih:A, 9fih:C, 9fii:A, 9fii:C, 9fij:A, 9fij:C, 9fil:A, 9fil:C, 6hl2:A, 6hl2:C, 6hl3:A, 6hl3:C, 6hl4:A, 6hl4:C, 6hla:A, 6hla:C, 6hli:A, 6hli:C, 6hlj:A, 6hlj:C, 6hlm:A, 6hlm:C, 7q5y:E, 7q5y:K, 7q5y:Q, 7q5y:W, 6q9c:A, 6q9c:C, 6q9g:A, 6q9g:C, 6q9j:A, 6q9j:C, 6q9k:A, 6q9k:C, 8qg1:A, 8qg1:C, 8qgw:A, 8qgw:C, 8qh4:A, 8qh4:C, 8qh7:A, 8qh7:C, 8qhk:A, 8qhk:C, 6r7p:A, 6r7p:C, 6saq:A, 6saq:C
19 8oh5:A 150 134 0.2430 0.3467 0.3881 6.44e-28 8oh5:D, 8oh5:G, 8oh5:J, 8oh9:A, 8oh9:D, 8oh9:G, 8oh9:J
20 7awt:E 156 157 0.2477 0.3397 0.3376 1.60e-27 7nyr:E, 7nyu:E, 7nyv:E, 7nz1:E, 7p61:E, 7p62:E, 7p63:E, 7p64:E, 7p69:E, 7p7c:E, 7p7e:E, 7p7j:E, 7p7k:E, 7p7l:E, 7p7m:E, 7z7r:E, 7z7s:E, 7z7t:E, 7z7v:E, 7z80:E, 7z83:E, 7z84:E, 7zc5:E, 7zci:E
21 6vw8:C 152 133 0.1869 0.2632 0.3008 1.86e-21 6vw7:A, 6vw7:C, 6vw8:A
22 6tg9:G 148 150 0.2009 0.2905 0.2867 1.64e-17 6tg9:C, 6tga:G, 6tga:C
23 2auv:A 85 82 0.1449 0.3647 0.3780 4.27e-17
24 7vw6:B 560 157 0.1916 0.0732 0.2611 2.16e-10 7e5z:B, 8j83:B, 7xqw:B
25 5xfa:A 581 119 0.1121 0.0413 0.2017 0.096 5xf9:A, 5xf9:E, 5xfa:E
26 8hfr:zp 88 59 0.0794 0.1932 0.2881 0.13 7bt6:z, 7btb:z, 6elz:z, 6em1:z, 6em5:z, 6ft6:z, 3jct:z, 6m62:z, 6n8j:z, 6n8k:z, 6n8l:z, 7nac:z, 7oh3:z, 7ohq:z, 7r7a:z, 7u0h:z, 7uoo:z, 7uqb:z, 7uqz:z, 7v08:z, 8v87:z, 6ylx:z, 6yly:z, 7z34:z
27 7p8n:B 613 81 0.0935 0.0326 0.2469 2.0 7p5h:B, 7p5h:E, 7p5h:b, 7p5h:e, 7p8n:b, 7p91:b, 7p91:B, 7p92:B
28 6h8k:H 154 16 0.0561 0.0779 0.7500 2.1 4wz7:H
29 3fpz:A 311 58 0.0701 0.0482 0.2586 2.1 3fpz:B, 4y4l:A, 4y4l:B, 4y4l:C, 4y4l:D
30 7p8n:a 642 66 0.0935 0.0312 0.3030 2.2 7p5h:A, 7p5h:D, 7p5h:a, 7p5h:d, 7p8n:A, 7p91:a, 7p91:A, 7p92:A
31 3fwx:A 165 94 0.1308 0.1697 0.2979 3.7 3fwx:B
32 3nwn:A 308 46 0.0794 0.0552 0.3696 4.4
33 8ibd:AB 418 42 0.0654 0.0335 0.3333 5.6 8iao:Ab, 8iar:Ab, 8ibd:Ab, 8ibg:AB, 8ibg:Ab
34 7q21:b 534 44 0.0701 0.0281 0.3409 6.4 7q21:B, 7qhm:B, 7qhm:O, 7qho:B, 7qho:O
35 3oti:A 379 61 0.0841 0.0475 0.2951 6.4 3oti:B
36 1f37:B 110 69 0.0701 0.1364 0.2174 6.6 1f37:A, 1m2a:A, 1m2a:B, 1m2b:A, 1m2b:B, 1m2d:A, 1m2d:B
37 6b3x:A 327 87 0.0981 0.0642 0.2414 8.0

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218