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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
DLTGAVSVVKVDEIQKQGENNPVKALQGRVPGMNITADGNPSGSATVRIRGIGTLNNNDPLYIIDGVPTKAGMHELNGND
IESIQVLKDAASASIYGSRAANGVIIITTKQGKKGQIKINFDASVSASMYQSKMNVLNTEQYGRAMWQAYVNDGENPNGN
ALGYAYNWGYNADGNPVLYGMTLSKYLDSKNTMPVADTDWFDEITRTGVIQQYNLSVSNGSEKGSSFFSLGYYKNLGVIK
DTDFDRFSARMNSDYKLIDDILTIGQHFTLNRTSEVQAPGGIIETALDIPSAIPVYASDGSWGGPVGGWPDRRNPRAVLE
YNKDNRYTYWRMFGDAYVNLTPFKGFNLRSTFGLDYANKQARYFTYPYQEGTQTNNGKSAVEAKQEHWTKWMWNAIATYQ
LEVGKHRGDVMIGMELNREDDSHFSGYKEDFSILTPDYMWPDAGSGTAQAYGAGEGYSLVSFFGKMNYSYADRYLLSLTL
RRDGSSRFGKNHRYATFPSVSLGWRITQENFMKELTWLDDLKLRASWGQTGNQEISNLARYTIYAPNYGTTDSFGGQSYG
TAYDITGSNGGGVLPSGFKRNQIGNDNIKWETTTQTNVGIDFSLFKQSLYGSLEYYYKKATDILTEMAGVGVLGEGGSRW
INSGAMKNQGFEFNLGYRNKTAFGLTYDLNGNISTYRNEILELPETVAANGKFGGNGVKSVVGHTYGAQVGYIADGIFKS
QDEVDNHATQEGAAVGRIRYRDIDHNGVIDERDQNWIYDPTPSFSYGLNIYLEYKNFDLTMFWQGVQGVDIISDVKKKSD
FWSASNVGFLNKGTRLLNAWSPTNPNSDIPALTRSDTNNEQRVSTYFVENGSFLKLRNIQLGYTVPAVISKKMRMDRLRF
YCSAQNLLTIKSKNFTGEDPENPNFSYPIPVNITFGLNIGF

The query sequence (length=921) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8aa0:A 924 921 1.0000 0.9968 1.0000 0.0 8aa0:I, 8aa1:A, 8aa1:I, 8aa2:A, 8aa2:I, 8aa3:A, 8aa3:I, 5t3r:D, 5t4y:C, 6z8i:B, 6z9a:B, 6zaz:B
2 8a9y:A 903 921 0.9674 0.9867 0.9674 0.0 8a9y:I
3 6sml:B 911 959 0.2856 0.2887 0.2742 6.82e-62 6sli:B, 6sli:D, 6sli:G, 6sli:J, 6slj:B, 6slj:A, 6sln:B, 6sln:A, 6sm3:B, 6smq:B, 6smq:E
4 5fq6:M 948 978 0.2443 0.2373 0.2301 7.31e-31 5fq6:D, 5fq6:I, 5fq6:B, 5fq7:D, 5fq7:B, 5fq8:B, 5fq8:D
5 5fr8:A 707 125 0.0445 0.0580 0.3280 1.46e-05 5fr8:B
6 5fp2:A 499 106 0.0369 0.0681 0.3208 1.96e-05
7 5fp2:B 538 109 0.0380 0.0651 0.3211 2.44e-05
8 5nc3:A 705 125 0.0391 0.0511 0.2880 1.45e-04 6i2j:A, 5nc4:A, 5nr2:A, 7obw:AAA, 6q5e:A, 6r1f:A, 6y47:A, 6yy5:AAA, 6z2n:AAA, 6z33:AAA
9 2gsk:A 590 119 0.0358 0.0559 0.2773 0.015 3m8d:A, 1nqg:A, 1nqh:A, 1ujw:A
10 8the:A 712 110 0.0358 0.0463 0.3000 0.11
11 3c8e:A 284 74 0.0228 0.0739 0.2838 1.8 3c8e:B
12 2guf:A 551 119 0.0347 0.0581 0.2689 1.9 3m8b:A, 1nqe:A, 1nqf:A, 3rgm:A, 3rgn:A
13 5ccb:B 371 36 0.0174 0.0431 0.4444 4.5 5ccx:B, 5cd1:E
14 7x0f:C 458 98 0.0282 0.0568 0.2653 4.6 7x0e:A, 7x0f:A, 7x0f:B, 7x0f:D, 7x17:A, 7x17:B, 7x17:C, 7x17:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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