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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
DLMLALALADRADELTRVRFGALDLRIDTKPDLTPVTDADRAVESDVRQTRDRPGDGVLEEFFTGRQWIVDPIDGTKNFV
RGVPVWASLIALLEDGVPSVGVVSAPALQRRWWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRE
RFIGLTDTVWRVRAYGDFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGPHGGSAVATNGLLHDE
VLTRLN

The query sequence (length=246) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5zon:A 256 254 1.0000 0.9609 0.9685 4.72e-168 5yht:A, 5yht:B, 5zon:B, 5zon:C, 5zon:D
2 2p3n:A 256 249 0.3049 0.2930 0.3012 3.92e-24 2p3n:B, 2p3n:C, 2p3n:D
3 5eq9:B 260 204 0.2764 0.2615 0.3333 6.04e-22 5eq8:A, 5eq9:A, 5eq9:C, 5eq9:D, 5t3j:A
4 4as5:A 274 241 0.2683 0.2409 0.2739 1.33e-16 4as5:B, 4as5:C, 4as5:D
5 2czi:A 259 235 0.2967 0.2819 0.3106 5.66e-16 2czh:B
6 2bji:A 274 243 0.2967 0.2664 0.3004 1.56e-15 2bji:B
7 3luz:B 234 193 0.2602 0.2735 0.3316 2.82e-14
8 3lv0:A 258 212 0.2724 0.2597 0.3160 4.35e-14 3luz:A, 3lv0:B
9 6giu:A 275 164 0.2033 0.1818 0.3049 5.39e-14 4as4:A, 4as4:B, 1awb:A, 1awb:B, 6giu:B, 6gj0:A, 6gj0:B, 2hhm:A, 2hhm:B, 1ima:A, 1ima:B, 1imb:A, 1imb:B, 1imc:A, 1imc:B, 1imd:A, 1imd:B, 1ime:A, 1ime:B, 6zk0:AAA, 6zk0:BBB
10 8wdq:A 273 241 0.3049 0.2747 0.3112 7.68e-14 8wdq:B
11 1dk4:A 252 165 0.1789 0.1746 0.2667 8.88e-14 1dk4:B, 1g0h:A, 1g0h:B, 1g0i:A, 1g0i:B
12 5dw8:A 260 225 0.2683 0.2538 0.2933 7.76e-13 5dw8:B, 5j16:A, 5j16:B, 5j16:C, 5j16:D
13 4hxv:A 317 202 0.2195 0.1703 0.2673 5.33e-12 4o7i:A
14 6ib8:B 270 204 0.2520 0.2296 0.3039 9.55e-12 6ib7:A, 6ib8:A, 2qfl:A, 6tqn:T, 6tqn:S, 6tqo:T, 6tqo:S
15 5eyg:B 265 183 0.1911 0.1774 0.2568 5.86e-11 5eyg:A, 5eyh:A, 5eyh:B, 5f24:A, 5f24:B, 4g61:A, 4g61:B, 4i3e:A, 4i3e:B, 4i3y:A, 4i3y:B, 4i40:A, 4i40:B, 4ptk:A, 4ptk:B, 3ryd:A, 3ryd:C
16 1k9y:A 354 218 0.2561 0.1780 0.2890 3.63e-10 1k9z:A, 1ka0:A, 1ka1:A, 1qgx:A
17 8f9y:A 352 109 0.1423 0.0994 0.3211 5.68e-07
18 6b5z:A 252 229 0.2602 0.2540 0.2795 1.09e-06 6b5z:B, 6b60:A, 6b60:B, 6b61:A, 6b61:B, 6b62:A, 6b62:B, 6b63:A, 6b63:B, 6b64:A, 6b64:B, 6b65:A, 6b65:B, 6b66:A, 6b66:B, 1lbx:A, 1lbx:B, 1lby:A, 1lby:B, 1lbz:A, 1lbz:B
19 2wef:A 303 163 0.1626 0.1320 0.2454 1.35e-06 1jp4:A
20 5djj:A 257 54 0.0935 0.0895 0.4259 0.006 5djg:A, 5djh:A, 5dji:A, 5djk:A
21 1inp:A 400 184 0.1789 0.1100 0.2391 0.20
22 3epy:A 88 38 0.0732 0.2045 0.4737 0.67 3epy:B
23 5w81:A 1173 58 0.0813 0.0171 0.3448 2.4
24 1lml:A 465 27 0.0488 0.0258 0.4444 2.7
25 9ax8:z 509 44 0.0569 0.0275 0.3182 3.5 3jcj:f, 3jcn:b, 5me0:W, 5me1:W, 6o7k:f, 6o9k:z
26 1zh8:A 325 64 0.0732 0.0554 0.2812 4.3 1zh8:B
27 7kir:A 326 170 0.1585 0.1196 0.2294 7.3 7kio:A
28 3voc:A 416 66 0.0772 0.0457 0.2879 8.6

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218