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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
DLHRDFTVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADH
YVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLCKNGVAFLGPPSEAMWALGDKIASTVVAQTLQ
VPTLPWSGSGLTVEWQGKRISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQVQS
EIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAPLAIFEFMEQCAIRLAKTVGYVS
AGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFETPSNPP
LARGHVIAARITSSGTVQELNFRSSKNVWGYFSVASQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLINLLE
TESFQNNDIDTGWLDY

The query sequence (length=496) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3jrx:A 496 496 1.0000 1.0000 1.0000 0.0 5kkn:B, 5kkn:C
2 3gid:A 460 484 0.9274 1.0000 0.9504 0.0 3gid:B
3 5csl:B 2072 514 0.6593 0.1578 0.6362 0.0 5ctb:A, 5ctb:C, 5ctc:A, 5ctc:B, 5ctc:C, 5cte:B, 5cte:C, 3h0s:A, 3k8x:A, 3k8x:B, 3k8x:C, 1od2:A, 1od2:B, 3pgq:A, 3pgq:C, 3tv5:A, 3tv5:B, 3tv5:C, 3tvu:A, 3tvu:B, 3tvu:C, 3tvw:A, 3tvw:B, 3tvw:C, 3tz3:A, 3tz3:B, 3tz3:C, 1w96:A, 1w96:B, 1w96:C, 4wyo:B, 4wyo:C, 4wz8:B, 4wz8:C
4 5csl:A 2050 516 0.6452 0.1561 0.6202 0.0
5 7ybu:A 670 490 0.3206 0.2373 0.3245 3.17e-69 7ybu:B, 7ybu:D, 7ybu:F, 7ybu:H, 7ybu:J
6 1dv2:A 450 485 0.3105 0.3422 0.3175 3.53e-63 1dv1:A, 1dv2:B, 3g8c:A, 3g8c:B, 3g8d:B, 2j9g:A, 2j9g:B, 3jzf:B, 3jzi:A, 3jzi:B, 6oi9:A, 6oi9:B, 3rup:A, 3rup:B, 3rv3:A, 3rv3:B, 3rv4:A, 2v58:A, 2v58:B, 2v59:A, 2v59:B, 2v5a:A, 2vr1:A, 2w6m:A, 2w6m:B, 2w6n:A, 2w6n:B, 2w6o:A, 2w6o:C, 2w6p:A, 2w6q:A, 2w6q:B, 2w6z:A, 2w70:A, 2w70:B, 2w71:A, 2w71:C
7 8rth:A 666 493 0.3065 0.2282 0.3083 3.81e-62 8rth:C, 8rth:E, 8rth:G, 8rth:I, 8rth:K
8 3ouu:A 446 494 0.2964 0.3296 0.2976 6.66e-62 3ouu:B, 3ouz:A, 3ouz:B
9 3n6r:G 646 483 0.3024 0.2322 0.3106 7.10e-62 3n6r:I, 3n6r:K
10 8hz4:A 456 468 0.3065 0.3333 0.3248 1.31e-61 8hz4:B, 8hz4:C, 8hz4:D
11 6ojh:A 445 500 0.3125 0.3483 0.3100 8.49e-61 4mv1:A, 4mv3:A, 4mv4:A, 4mv8:A, 6oi8:A
12 1dv1:B 428 478 0.2964 0.3435 0.3075 4.13e-60
13 8j78:I 651 483 0.3105 0.2366 0.3188 6.41e-60 8j78:C, 8j7d:D, 8j7d:F, 8j7d:I, 8j7d:L, 8jaw:A, 8jaw:C, 8jaw:E, 8jaw:F, 8jaw:H, 8jaw:K, 8k2v:A, 8k2v:B, 8k2v:C, 8k2v:D, 8k2v:E, 8k2v:F
14 7kct:A 453 482 0.3004 0.3289 0.3091 6.92e-58 7kbl:A, 7kbl:B, 7kc7:A, 7kct:B
15 4rzq:A 422 496 0.2984 0.3507 0.2984 1.47e-57 4mv6:A, 4mv7:A, 4mv9:A
16 2vpq:B 448 481 0.3004 0.3326 0.3098 2.07e-57 2vpq:A
17 3bg5:A 1137 489 0.3004 0.1310 0.3047 2.57e-57 3bg5:C, 8gk8:A, 8gk8:B, 3hb9:A, 3hb9:C, 3hbl:A, 3hbl:C, 4hnt:A, 4hnt:C, 4hnu:A, 4hnu:C, 4hnv:A, 4hnv:C
18 3tw6:B 1129 514 0.3105 0.1364 0.2996 3.48e-57 4jx4:A, 4jx4:B, 4jx4:C, 4jx4:D, 4jx5:A, 4jx5:B, 4jx5:C, 4jx5:D, 4jx6:A, 4jx6:B, 4jx6:C, 4jx6:D, 4loc:A, 4loc:B, 4loc:C, 4loc:D, 4m6v:A, 4m6v:B, 4m6v:C, 4m6v:D, 4mfd:A, 4mfd:B, 4mfd:C, 4mfd:D, 4mfe:A, 4mfe:B, 4mfe:C, 4mfe:D, 4mim:A, 4mim:B, 4mim:C, 4mim:D, 3tw6:C, 3tw6:D
19 8sgx:X 657 476 0.3044 0.2298 0.3172 4.39e-57 8sgx:S, 8sgx:Z, 8sgx:V, 8sgy:V, 8sgy:B, 8sgy:S, 8sgy:Z, 8sgy:Y, 8sgz:V, 8sgz:Z, 8sgz:X, 8sgz:S, 8sgz:B, 8sgz:Y
20 2vqd:A 447 498 0.2984 0.3311 0.2972 1.92e-55
21 5vyz:A 1144 487 0.3024 0.1311 0.3080 7.77e-54 5vyw:D, 5vyz:B, 5vyz:D, 5vz0:A, 5vz0:B, 5vz0:D, 7zyy:A, 7zyy:C, 7zyy:B, 7zyy:D, 7zyz:A, 7zz0:A, 7zz1:A, 7zz2:A, 7zz3:A, 7zz3:C, 7zz3:B, 7zz3:D, 7zz4:A, 7zz5:A, 7zz6:D, 7zz6:A, 7zz8:A, 7zz8:C, 7zz8:D, 7zz8:B
22 7wtb:B 1147 501 0.3044 0.1316 0.3014 7.40e-53 3bg3:A, 3bg3:B, 3bg3:C, 3bg3:D, 3bg9:A, 3bg9:B, 3bg9:C, 3bg9:D, 8j7o:A, 8j7o:B, 8j7o:C, 8j7o:E, 7wta:C, 7wta:B, 7wta:D, 7wta:A, 7wtb:C, 7wtb:A, 7wtb:D, 7wtc:C, 7wtc:A, 7wtc:B, 7wtc:D, 7wtd:C, 7wtd:D, 7wte:C, 7wte:D
23 2qf7:B 1017 509 0.2923 0.1426 0.2849 1.73e-42 3tw7:A, 3tw7:B
24 8hwl:A 941 261 0.1976 0.1041 0.3755 1.81e-40 8hwl:B, 8hwl:C, 8hwl:E
25 3jzf:A 380 262 0.1956 0.2553 0.3702 1.93e-39
26 3jzf:A 380 143 0.0746 0.0974 0.2587 5.84e-11
27 8jxn:J 541 248 0.1815 0.1664 0.3629 1.32e-36
28 8jxn:J 541 78 0.0504 0.0462 0.3205 6.64e-04
29 4qsh:C 1081 290 0.2016 0.0925 0.3448 4.81e-36 4qsh:A, 4qsh:D, 4qsh:B, 4qsk:A, 4qsk:B
30 4qsh:C 1081 144 0.0887 0.0407 0.3056 2.10e-11 4qsh:A, 4qsh:D, 4qsh:B, 4qsk:A, 4qsk:B
31 5vyz:C 1083 266 0.1895 0.0868 0.3534 4.93e-35 5vyw:A, 5vyw:B, 5vyw:C, 5vz0:C
32 5vyz:C 1083 144 0.0746 0.0342 0.2569 0.002 5vyw:A, 5vyw:B, 5vyw:C, 5vz0:C
33 2qf7:A 1076 283 0.1915 0.0883 0.3357 3.07e-34 3tw6:A
34 2qf7:A 1076 160 0.0887 0.0409 0.2750 1.13e-08 3tw6:A
35 3bg5:B 1074 271 0.1815 0.0838 0.3321 5.48e-34 3bg5:D, 8gk8:C, 3hb9:B, 3hb9:D, 3hbl:B, 3hbl:D, 4hnt:B, 4hnt:D, 4hnu:B, 4hnu:D, 4hnv:D, 3ho8:A, 3ho8:C, 3ho8:B
36 3bg5:B 1074 142 0.0847 0.0391 0.2958 1.45e-11 3bg5:D, 8gk8:C, 3hb9:B, 3hb9:D, 3hbl:B, 3hbl:D, 4hnt:B, 4hnt:D, 4hnu:B, 4hnu:D, 4hnv:D, 3ho8:A, 3ho8:C, 3ho8:B
37 3ho8:D 934 271 0.1815 0.0964 0.3321 6.08e-34
38 3ho8:D 934 142 0.0847 0.0450 0.2958 1.15e-11
39 3n6r:A 591 279 0.1835 0.1540 0.3262 7.98e-34 3n6r:C, 3n6r:E
40 3n6r:A 591 151 0.1008 0.0846 0.3311 5.12e-15 3n6r:C, 3n6r:E
41 4hnv:B 1033 259 0.1653 0.0794 0.3166 3.31e-33 8gk8:D
42 4hnv:B 1033 142 0.0827 0.0397 0.2887 9.18e-11 8gk8:D
43 8hz5:A 350 235 0.1673 0.2371 0.3532 5.12e-31
44 8hz5:A 350 153 0.0927 0.1314 0.3007 7.38e-12
45 3va7:A 1130 257 0.1673 0.0735 0.3230 3.52e-27
46 3va7:A 1130 141 0.0806 0.0354 0.2837 3.45e-11
47 5dou:D 1430 233 0.1048 0.0364 0.2232 1.56e-06 5dou:A, 5dou:B, 5dou:C, 6w2j:A
48 1bxr:A 1073 213 0.0887 0.0410 0.2066 0.001 1a9x:A, 1a9x:C, 1a9x:E, 1a9x:G, 1bxr:C, 1bxr:E, 1bxr:G, 1c30:A, 1c30:C, 1c30:E, 1c30:G, 1c3o:A, 1c3o:C, 1c3o:E, 1c3o:G, 1ce8:A, 1ce8:C, 1ce8:E, 1ce8:G, 1cs0:A, 1cs0:C, 1cs0:E, 1cs0:G, 1jdb:B, 1jdb:E, 1jdb:H, 1jdb:K, 1kee:A, 1kee:C, 1kee:E, 1kee:G, 1m6v:A, 1m6v:C, 1m6v:E, 1m6v:G, 1t36:A, 1t36:C, 1t36:E, 1t36:G
49 1bxr:A 1073 216 0.0927 0.0429 0.2130 0.45 1a9x:A, 1a9x:C, 1a9x:E, 1a9x:G, 1bxr:C, 1bxr:E, 1bxr:G, 1c30:A, 1c30:C, 1c30:E, 1c30:G, 1c3o:A, 1c3o:C, 1c3o:E, 1c3o:G, 1ce8:A, 1ce8:C, 1ce8:E, 1ce8:G, 1cs0:A, 1cs0:C, 1cs0:E, 1cs0:G, 1jdb:B, 1jdb:E, 1jdb:H, 1jdb:K, 1kee:A, 1kee:C, 1kee:E, 1kee:G, 1m6v:A, 1m6v:C, 1m6v:E, 1m6v:G, 1t36:A, 1t36:C, 1t36:E, 1t36:G
50 6uel:A 1333 122 0.0504 0.0188 0.2049 0.074 6uel:B
51 7lgm:A 719 32 0.0262 0.0181 0.4062 0.086 7lgm:B
52 6w2j:B 1364 174 0.0726 0.0264 0.2069 0.19
53 8evy:B 317 87 0.0464 0.0726 0.2644 0.24 8evy:A, 8evy:C, 8evz:A, 8evz:B, 8evz:C
54 1f7u:A 606 139 0.0706 0.0578 0.2518 1.1 1bs2:A, 1f7v:A
55 3nwa:A 608 112 0.0504 0.0411 0.2232 1.6 4hsi:C, 3nw8:B, 3nw8:A, 3nw8:C, 3nwa:B, 3nwa:C, 3nwa:D, 3nwd:C, 3nwf:A, 3nwf:B
56 5ifw:B 702 94 0.0464 0.0328 0.2447 2.0
57 3arq:A 575 38 0.0302 0.0261 0.3947 2.1 3arp:A, 3arr:A, 3art:A, 3aru:A, 3arv:A, 3arw:A, 3arx:A, 3ary:A, 3arz:A, 3as0:A, 3as1:A, 3as2:A, 3as3:A, 8hrf:A, 8hrf:B
58 8dgc:A 2028 123 0.0665 0.0163 0.2683 2.3 8dgc:B, 8dgc:C, 8dgc:D
59 2r86:A 334 129 0.0605 0.0898 0.2326 3.2 2r84:A, 2r85:A, 2r85:B, 2r86:B, 2r87:A, 2r87:B, 2r87:C, 2r87:D, 2r87:E, 2r87:F
60 6opc:B 741 59 0.0383 0.0256 0.3220 3.4 8dar:A, 8dar:B, 8dar:C, 8dar:D, 8dar:E, 8dar:F, 8das:A, 8das:B, 8das:C, 8das:D, 8das:E, 8das:F, 8dat:A, 8dat:B, 8dat:C, 8dat:D, 8dat:E, 8dat:F, 8dau:A, 8dau:B, 8dau:C, 8dau:D, 8dau:E, 8dau:F, 8dav:A, 8dav:B, 8dav:C, 8dav:D, 8dav:E, 8dav:F, 8daw:A, 8daw:B, 8daw:C, 8daw:D, 8daw:E, 8daw:F, 6oa9:A, 6oa9:B, 6oa9:C, 6oa9:E, 6oa9:F, 6oaa:B, 6oaa:C, 6oaa:D, 6oab:D, 6oab:B, 6oab:C, 6oab:A, 6omb:A, 6omb:B, 6omb:C, 6omb:D, 6omb:E, 6opc:A, 6opc:C, 6opc:D, 6opc:E
61 6oa9:D 489 58 0.0383 0.0389 0.3276 4.1 6oaa:E, 6oab:E
62 4nap:D 310 63 0.0363 0.0581 0.2857 4.1 4nap:A, 4nap:B, 4nap:C, 4pgn:A, 4pgn:B, 4pgn:C, 4pgn:D, 4pgp:A, 4pgp:B, 4pgp:C, 4pgp:D
63 2dwc:B 409 129 0.0685 0.0831 0.2636 4.3 2dwc:A
64 6esq:I 347 51 0.0302 0.0432 0.2941 6.1
65 8t2j:A 339 63 0.0323 0.0472 0.2540 6.3
66 6chs:H 550 71 0.0444 0.0400 0.3099 6.4 6chs:I, 6chs:J, 6chs:D, 6chs:E, 6chs:F
67 6rus:B 220 44 0.0302 0.0682 0.3409 7.5 7b26:B, 7noz:D, 8q6r:D, 8q6r:F, 6rur:V, 6rur:Y, 6ruv:V, 6ruv:Y, 6rv6:B, 6s08:A, 6s0a:A, 6s0b:A, 6sej:B
68 6fyq:A 443 70 0.0423 0.0474 0.3000 8.3
69 8dko:B 393 80 0.0403 0.0509 0.2500 8.9 8dko:A, 8dkp:A, 8dkp:B, 8dkq:B, 8w0k:B
70 1jdi:A 223 27 0.0242 0.0538 0.4444 9.3 1jdi:B, 1jdi:C, 1jdi:D, 1jdi:E, 1jdi:F, 1k0w:A, 1k0w:B, 1k0w:C, 1k0w:D, 1k0w:E, 1k0w:F
71 3aw8:A 360 239 0.1069 0.1472 0.2218 9.6 3aw8:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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