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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
DLEGTTKRFEHLLSLSGLFKHFIESKADPKFRQVLDVLEENQFRESPAYVNGQLRPYQIQGVNWLVSLHKNKIAGILADE
MGLGKTLQTISFLGYLRYIEKIPGPFLVIAPKSTLNNWLREINRWTPDVNAFILQGDKEERAELIQKKLLGCDFDVVIAS
YEIIIREKSPLKKINWEYIIIDEAHRIKNEESMLSQVLREFTSRNRLLITGTPLQNNLHELWALLNFLLPDIFSDAQDFD
DWFSSESTEEDQDKIVKQLHTVLQPFLLRRIKSDVETSLLPKKELNLYVGMSSMQKKWYKKILEKDESKTRLLNIMMQLR
KCCNHPYLFDGAEPGPPYTTDEHLVYNAAKLQVLDKLLKKLKEEGSRVLIFSQMSRLLDILEDYCYFRNYEYCRIDGSTA
HEDRIQAIDDYNAPDSKKFVFLLTTRAGGLGINLTSADVVVLYDSDWNPQADLQAMDRAHRIGQKKQVKVFRLVTDNSVE
EKILERATQKLRLDQLVIQQNRTS

The query sequence (length=504) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7x3t:V 792 504 1.0000 0.6364 1.0000 0.0 6iro:L, 6jyl:K, 6k1p:K, 7x3w:K, 2y9z:A
2 6pwf:K 454 458 0.6925 0.7687 0.7620 0.0
3 6ne3:W 461 470 0.6091 0.6659 0.6532 0.0 8v4y:W, 8v6v:W, 8v6v:X, 8v7l:W
4 6vz4:K 616 473 0.4524 0.3701 0.4820 1.36e-151 6kw3:Y, 6kw4:Y, 6kw5:Q
5 7y8r:I 732 500 0.4623 0.3183 0.4660 5.00e-149
6 6uxw:A 778 504 0.4603 0.2982 0.4603 1.00e-148 7egp:A, 6iy2:O, 6iy3:O, 6uxv:A, 5x0x:O, 5x0y:O, 5z3l:O, 5z3o:O, 5z3u:O, 5z3v:O
7 6tda:S 783 472 0.4484 0.2886 0.4788 4.06e-148
8 7vdv:A 809 494 0.4603 0.2868 0.4696 5.18e-148 7vdt:A
9 8kcc:K 508 457 0.4444 0.4409 0.4902 6.98e-144 8j90:K, 8kcb:K, 8wh5:K, 8wh8:K, 8wh9:K, 8wha:K, 8wha:L
10 8atf:G 442 461 0.4187 0.4774 0.4577 5.46e-140 8oo9:G, 8oos:G
11 9gd1:W 849 472 0.4325 0.2568 0.4619 7.54e-140
12 7ux9:P 468 475 0.4444 0.4786 0.4716 2.58e-139
13 5jxt:M 324 236 0.3710 0.5772 0.7924 4.16e-139 5jxt:N, 5jxt:O, 5jxt:J, 5jxt:K, 5jxt:I, 5jxt:H
14 7tn2:W 895 487 0.4345 0.2447 0.4497 1.77e-138 9gd2:W, 9gd3:W
15 6ftx:W 878 474 0.4246 0.2437 0.4515 1.20e-134 6g0l:W, 5j70:A, 5j70:B, 3mwy:W, 3ted:A
16 6g0l:M 855 460 0.4167 0.2456 0.4565 2.29e-134 7nkx:W, 5o9g:W
17 7epu:B 748 453 0.4206 0.2834 0.4680 1.55e-133 8b0a:K, 7enn:K, 7otq:K
18 5hzr:A 552 499 0.4147 0.3786 0.4188 7.79e-129
19 6ryr:W 708 504 0.4425 0.3150 0.4425 1.81e-126 2l75:A, 1mm2:A, 6q3m:D, 6ryu:W, 6ryu:V
20 8b3f:b 534 479 0.3671 0.3464 0.3862 7.99e-101 8b3d:b, 7oo3:b, 7oob:b, 7oop:b, 7opc:b, 7opd:b
21 8he5:O 516 482 0.3472 0.3391 0.3631 1.68e-89
22 8tvy:M 558 487 0.3194 0.2885 0.3306 5.23e-86 5vvr:M
23 7zke:E 1623 526 0.3730 0.1158 0.3574 7.23e-84
24 7z8s:E 1514 487 0.3472 0.1156 0.3593 1.88e-83 7zb5:E, 7zb5:H
25 7xyf:K 656 511 0.3492 0.2683 0.3444 9.50e-77 7xyg:K
26 6fml:G 731 311 0.2540 0.1751 0.4116 2.69e-74 8av6:G
27 6fml:G 731 155 0.1706 0.1176 0.5548 6.02e-51 8av6:G
28 8x19:I 864 330 0.2659 0.1551 0.4061 2.55e-73 8x1c:I
29 8x19:I 864 154 0.1567 0.0914 0.5130 1.87e-45 8x1c:I
30 7zi4:G 682 285 0.2341 0.1730 0.4140 1.43e-71
31 7zi4:G 682 157 0.1647 0.1217 0.5287 2.36e-48
32 8oo7:G 704 301 0.2401 0.1719 0.4020 2.07e-69 8oop:G
33 8oo7:G 704 155 0.1706 0.1222 0.5548 3.55e-51 8oop:G
34 6gej:M 688 330 0.2599 0.1904 0.3970 3.65e-69 6gen:M
35 6gej:M 688 157 0.1548 0.1134 0.4968 5.70e-44 6gen:M
36 6eg2:A 619 243 0.2242 0.1826 0.4650 6.77e-68 6eg3:A
37 1z63:A 468 450 0.2758 0.2970 0.3089 1.86e-67 1z63:B
38 1z3i:X 644 497 0.3115 0.2438 0.3159 1.55e-66
39 8x15:I 792 305 0.2163 0.1376 0.3574 3.84e-45
40 8x15:I 792 152 0.1468 0.0934 0.4868 1.67e-39
41 7z7n:E 1306 266 0.1786 0.0689 0.3383 4.90e-39
42 9c57:G 878 146 0.1270 0.0729 0.4384 1.88e-28
43 9c57:G 878 307 0.1587 0.0911 0.2606 2.36e-21
44 8eu9:Q 426 149 0.1270 0.1502 0.4295 3.55e-28 8ets:Q, 8etu:Q, 8euf:Q
45 8eu9:Q 426 60 0.0417 0.0493 0.3500 0.002 8ets:Q, 8etu:Q, 8euf:Q
46 6l8n:A 810 162 0.1131 0.0704 0.3519 4.33e-20
47 6l8n:A 810 293 0.1726 0.1074 0.2969 9.97e-20
48 8sp4:A 859 210 0.1171 0.0687 0.2810 4.18e-08 8spg:A
49 8sp4:A 859 49 0.0317 0.0186 0.3265 3.1 8spg:A
50 6rfl:Y 600 442 0.1944 0.1633 0.2217 1.40e-07 7aoh:Y, 8c8h:Y
51 7liu:A 442 142 0.0734 0.0837 0.2606 0.001 6cz5:A, 5e7j:A, 5e7m:A, 2i4i:A, 7liu:B, 4px9:A, 4px9:B, 4px9:C, 4pxa:A, 8ssw:A, 8ssw:B
52 4d26:A 430 143 0.0754 0.0884 0.2657 0.001 4d25:A
53 8y6o:I 597 147 0.0734 0.0620 0.2517 0.001 8qp8:G, 6qw6:5X, 6qx9:5X, 8r08:G
54 2db3:A 420 153 0.0675 0.0810 0.2222 0.017 2db3:B, 2db3:C, 2db3:D
55 7zsa:7 616 429 0.1667 0.1364 0.1958 0.041 8cen:7, 8ceo:7, 7o4i:7, 7o4j:7, 7o4k:7, 7o4l:7, 7o72:7, 7o73:7, 7o75:7, 7zs9:7, 7zsb:7
56 7k04:7 638 429 0.1667 0.1317 0.1958 0.041 5fmf:1, 7m2u:7, 7ml0:7, 7ml1:7, 7ml2:7, 5sva:Z
57 7ml3:7 548 429 0.1667 0.1533 0.1958 0.043
58 6z6p:M 534 170 0.0853 0.0805 0.2529 0.076
59 7r7j:B 574 168 0.0952 0.0836 0.2857 0.14 8h5y:B, 8h5y:A, 8h5z:B, 8h5z:A, 6jde:B, 6jde:A, 7r7j:A
60 7r76:A 1834 100 0.0516 0.0142 0.2600 0.21 7r77:A
61 7r78:A 1880 100 0.0516 0.0138 0.2600 0.22
62 5elx:A 391 124 0.0714 0.0921 0.2903 0.23 3peu:A, 3pev:A, 3pew:A, 3pey:A, 3rrm:A, 3rrn:A
63 7v4r:A 437 161 0.0833 0.0961 0.2609 0.27
64 5v9x:A 772 76 0.0437 0.0285 0.2895 0.50
65 6o5f:A 417 110 0.0556 0.0671 0.2545 0.72 6o5f:B
66 4q4k:A 351 60 0.0357 0.0513 0.3000 1.1 4q4k:B, 4qis:A, 4qis:B, 4qit:A, 4qit:B, 4qiu:A, 4qiu:B
67 7ena:6 652 186 0.0813 0.0629 0.2204 1.5 7ad8:A, 8bvw:0, 8ebs:A, 8ebv:A, 8ebw:A, 7egb:6, 7egc:6, 7enc:6, 8gxq:HH, 8gxs:HH, 5ivw:V, 5iy6:V, 5iy7:V, 5iy8:V, 5iy9:V, 7nvr:7, 7nvv:7, 7nvw:7, 7nvx:7, 7nvy:7, 7nvz:7, 7nw0:7, 6o9l:7, 6ro4:A, 8wak:6, 8wal:6, 8wan:6, 8wao:6, 8wap:6, 8waq:6, 8war:6, 8was:6
68 8ebu:A 604 186 0.0813 0.0679 0.2204 2.1 8ebt:A, 8ebx:A, 8eby:A
69 7lbm:W 574 170 0.0734 0.0645 0.2176 2.1
70 3ueq:A 632 70 0.0437 0.0348 0.3143 2.7 4fls:A, 1jg9:A, 1jgi:A, 1mvy:A, 1mw0:A, 1mw1:A, 1mw2:A, 1mw3:A, 5n6v:A, 5n7j:A, 1s46:A, 1zs2:A
71 7plm:A 1177 38 0.0317 0.0136 0.4211 4.1 7plm:B
72 1b0p:A 1231 38 0.0317 0.0130 0.4211 4.2 1b0p:B, 2c3m:A, 2c3m:B, 2c3o:A, 2c3o:B, 2c3p:A, 2c3p:B, 2c3u:A, 2c3u:B, 2c3y:A, 2c3y:B, 2c42:A, 2c42:B, 1kek:A, 1kek:B, 2pda:A, 2pda:B, 2uza:A, 2uza:B
73 4a36:A 523 82 0.0397 0.0382 0.2439 4.3 4a36:B
74 3ct8:A 133 27 0.0238 0.0902 0.4444 6.2
75 5gkd:A 726 183 0.0952 0.0661 0.2623 6.3 5gkd:B, 5gkd:C, 5gkd:D, 5gkq:A, 5gkq:B
76 8fkv:NI 647 87 0.0476 0.0371 0.2759 6.4 8fkt:NI, 8fku:NI, 8fkw:NI, 8fkx:NI, 8fky:NI
77 3o8o:E 752 52 0.0337 0.0226 0.3269 6.8 3o8o:A, 3o8o:C, 3o8o:G
78 6o3v:B 831 95 0.0536 0.0325 0.2842 7.4 6o3v:A, 6o3v:C, 6o6b:A, 6o6b:B, 6o6b:C, 6o6b:D
79 4cdn:A 463 37 0.0317 0.0346 0.4324 8.0 4cdm:A, 7f8t:A, 8kcm:A, 5o86:A, 5o8d:A, 5o8e:A, 8oet:A, 8oy3:A, 8oy4:A, 8oy5:A, 8oy6:A, 8oy7:A, 8oy8:A, 8oy9:A, 8oya:A, 8oyb:A, 8oyc:A, 7viw:A, 7vix:A, 7viy:A, 7viz:A, 7vj0:A, 7vj1:A, 7vj2:A, 7vj3:A, 7vj4:A, 7vj5:A, 7vj6:A, 7vj7:A, 7vj8:A, 7vj9:A, 7vja:A, 7vjb:A, 7vjc:A, 7vje:A, 7vjg:A, 7vjh:A, 7vji:A, 7vjj:A, 7vjk:A, 2xry:A, 2xrz:A, 7yc7:A, 7ycm:A, 7ycp:A, 7ycr:A, 7yd6:A, 7yd7:A, 7yd8:A, 7ydz:A, 7ye0:A, 7yeb:A, 7yec:A, 7yee:A, 7yei:A, 7yej:A, 7yek:A, 7yel:A, 7yem:A, 5zcw:A
80 4cdn:B 438 37 0.0317 0.0365 0.4324 8.6 8kcm:B, 8oet:B, 8oy3:B, 8oy4:B, 8oy5:B, 8oy6:B, 8oy7:B, 8oy8:B, 8oy9:B, 8oya:B, 8oyb:B, 8oyc:B, 2xrz:B, 7yc7:B, 7ycm:B, 7ycp:B, 7ycr:B, 7yd6:B, 7yd7:B, 7yd8:B, 7ydz:B, 7ye0:B, 7yeb:B, 7yec:B, 7yee:B, 7yei:B, 7yej:B, 7yek:B, 7yel:B, 7yem:B, 5zcw:B
81 6g1g:A 211 92 0.0456 0.1090 0.2500 8.8 6g1i:A, 6g1i:B, 2xqo:A
82 5diy:A 463 88 0.0417 0.0454 0.2386 9.2 5diy:B
83 3f41:A 590 53 0.0298 0.0254 0.2830 9.3 3f41:B, 4wu3:A, 4wu3:B, 4wu3:C, 4wu3:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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