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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
DKKYSIGLAIGTNSVGWAVITDEYKVPSKKFKVLGNTDRHSIKKNLIGALLFDSGETAEATRLKRTARRRYTRRKNRICY
LQEIFSNEMAKVDDSFFHRLEESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAHM
IKFRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINASGVDAKAILSARLSKSRRLENLIAQLPGEKKNGLFGNL
IALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLDNLLAQIGDQYADLFLAAKNLSDAILLSDILRVNTEITKAPLSASM
IKRYDEHHQDLTLLKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLVKLNREDLLRK
QRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARGNSRFAWMTRKSEETITPWNFEEV
VDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYFTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTV
KQLKEDYFKKIECFDSVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDREMIEERLKTYAH
LFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFMQLIHDDSLTFKEDIQKAQVSLHEHIAN
LAGSPAIKKGILQTVKVVDELVKVMGRHKPENIVIEMARENELDKAGFIKRQLVETRQITKHVAQILDSRMNTKYDENDK
LIREVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLNAVVGTALIKKYPKLESEFVYFFYSNIMNFFKTEITLAN
GEIRKRPLIETNGETGEIVWDKGRDFATVRKVLSMPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGF
DSPTVAYSVLVVAKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVKKDLIIKLPKYSLFELENGRKRML
ASAGELQKGNELALPSKYVNFLYLASHYESPEDNEQKQLFVEQHKHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHR
DKPIREQAENIIHLFTLTNLGAPAAFKYFDTTIDRKRYTSTKEVLDATLIHQSITGLYETRIDLSQLG

The query sequence (length=1188) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7z4g:B 1188 1188 1.0000 1.0000 1.0000 0.0 7zo1:B
2 7z4d:B 1259 1258 0.9966 0.9404 0.9412 0.0
3 4oo8:D 1163 1189 0.9747 0.9957 0.9739 0.0
4 8t6t:A 1168 1197 0.9638 0.9803 0.9566 0.0 8t7s:G
5 8t6y:A 1148 1192 0.9512 0.9843 0.9480 0.0 8t6o:A, 8t79:A
6 4zt9:C 1160 1208 0.9545 0.9776 0.9387 0.0
7 7z4d:E 1166 1223 0.9478 0.9657 0.9207 0.0
8 7s4v:A 1122 1191 0.9394 0.9947 0.9370 0.0 6o0x:A, 8t6p:A
9 7s4u:A 1092 1191 0.9141 0.9945 0.9118 0.0
10 8t76:A 1088 1192 0.9015 0.9844 0.8985 0.0
11 8t6s:A 962 1193 0.7567 0.9345 0.7536 0.0
12 5y36:A 1368 772 0.6414 0.5570 0.9870 0.0 5f9r:B, 6ifo:A, 6ifo:B, 6mcb:A, 6mcc:A, 7s36:P, 7s38:P, 7s4x:A, 7v59:B, 7v59:E, 5vw1:A, 5vzl:A, 8ye6:A, 8ye9:A, 7z4c:B, 7z4e:B, 7z4k:B, 4zt0:A
13 5y36:A 1368 478 0.3628 0.3151 0.9017 0.0 5f9r:B, 6ifo:A, 6ifo:B, 6mcb:A, 6mcc:A, 7s36:P, 7s38:P, 7s4x:A, 7v59:B, 7v59:E, 5vw1:A, 5vzl:A, 8ye6:A, 8ye9:A, 7z4c:B, 7z4e:B, 7z4k:B, 4zt0:A
14 7z4j:B 1345 772 0.6406 0.5658 0.9858 0.0 6aeb:B, 6aeb:F, 6aeg:B, 6ai6:A, 5b2t:B, 5fw2:B, 5fw3:B, 8fzt:E, 6k4p:B, 6k4q:B, 8kah:B, 8kai:B, 8kaj:B, 8kak:B, 8kak:F, 8kal:B, 8kal:G, 8kam:B, 7ox7:B, 7ox8:B, 7ox9:B, 7oxa:B, 7qqo:B, 7qqp:B, 7qqq:B, 7qqr:B, 7qqs:B, 7qqt:B, 7qqu:B, 7qqv:B, 7qqx:B, 7qqz:B, 7qr0:B, 7qr1:B, 7qr5:B, 7qr7:B, 7qr8:B, 8wuv:A, 8ygj:A
15 7z4j:B 1345 463 0.3586 0.3167 0.9201 0.0 6aeb:B, 6aeb:F, 6aeg:B, 6ai6:A, 5b2t:B, 5fw2:B, 5fw3:B, 8fzt:E, 6k4p:B, 6k4q:B, 8kah:B, 8kai:B, 8kaj:B, 8kak:B, 8kak:F, 8kal:B, 8kal:G, 8kam:B, 7ox7:B, 7ox8:B, 7ox9:B, 7oxa:B, 7qqo:B, 7qqp:B, 7qqq:B, 7qqr:B, 7qqs:B, 7qqt:B, 7qqu:B, 7qqv:B, 7qqx:B, 7qqz:B, 7qr0:B, 7qr1:B, 7qr5:B, 7qr7:B, 7qr8:B, 8wuv:A, 8ygj:A
16 8t77:A 1025 972 0.6768 0.7844 0.8272 0.0
17 8t77:A 1025 227 0.1852 0.2146 0.9692 1.49e-126
18 5b2r:B 1319 757 0.6305 0.5679 0.9894 0.0 5b2s:B, 5fq5:B, 5fw1:B, 8g1i:A, 6k3z:B, 6k4s:B, 6k4u:B, 6k57:B, 7qqw:B, 4un3:B, 4un4:B, 4un5:B, 8wus:A, 8wut:A, 8wuu:A
19 5b2r:B 1319 455 0.3594 0.3237 0.9385 0.0 5b2s:B, 5fq5:B, 5fw1:B, 8g1i:A, 6k3z:B, 6k4s:B, 6k4u:B, 6k57:B, 7qqw:B, 4un3:B, 4un4:B, 4un5:B, 8wus:A, 8wut:A, 8wuu:A
20 8kag:B 1346 763 0.6322 0.5579 0.9843 0.0 8kah:F, 8kai:F, 8kaj:F, 8spq:A, 8sqh:A, 8srs:A, 8tzz:A, 8u3y:A, 6vpc:B, 7z4h:B, 7z4i:B, 7z4l:B, 4zt9:A
21 8kag:B 1346 478 0.3628 0.3202 0.9017 0.0 8kah:F, 8kai:F, 8kaj:F, 8spq:A, 8sqh:A, 8srs:A, 8tzz:A, 8u3y:A, 6vpc:B, 7z4h:B, 7z4i:B, 7z4l:B, 4zt9:A
22 4oo8:A 1301 762 0.6330 0.5780 0.9869 0.0 4zt0:C
23 4oo8:A 1301 462 0.3426 0.3128 0.8810 0.0 4zt0:C
24 8t7s:A 1312 766 0.6128 0.5549 0.9504 0.0
25 8t7s:A 1312 461 0.3544 0.3209 0.9132 0.0
26 5xbl:A 1320 761 0.6069 0.5462 0.9474 0.0
27 5xbl:A 1320 478 0.3628 0.3265 0.9017 0.0
28 6o0z:A 1288 758 0.6035 0.5567 0.9459 0.0
29 6o0z:A 1288 462 0.3628 0.3346 0.9329 0.0
30 8t6x:A 1278 766 0.5808 0.5399 0.9008 0.0
31 8t6x:A 1278 465 0.3544 0.3294 0.9054 0.0
32 4cmq:B 1168 759 0.5547 0.5642 0.8682 0.0 4cmp:B, 4cmq:A
33 4cmq:B 1168 445 0.3089 0.3142 0.8247 0.0 4cmp:B, 4cmq:A
34 6o0y:A 1146 458 0.3805 0.3944 0.9869 0.0
35 6o0y:A 1146 451 0.3199 0.3316 0.8426 0.0
36 6o0y:A 1146 172 0.1439 0.1492 0.9942 3.54e-105
37 8pj9:A 1051 910 0.4141 0.4681 0.5407 0.0
38 8pj9:A 1051 193 0.1136 0.1284 0.6995 4.17e-66
39 7s37:P 1033 445 0.3476 0.3998 0.9281 0.0 7s3h:P
40 7s37:P 1033 478 0.3359 0.3863 0.8347 0.0 7s3h:P
41 7s37:P 1033 55 0.0421 0.0484 0.9091 7.51e-23 7s3h:P
42 8t78:A 863 613 0.3805 0.5238 0.7374 0.0
43 8t78:A 863 218 0.1801 0.2480 0.9817 1.97e-140
44 8t78:A 863 216 0.1549 0.2132 0.8519 2.59e-100
45 8uza:A 910 411 0.0859 0.1121 0.2482 6.36e-12 8uzb:A
46 8uza:A 910 18 0.0109 0.0143 0.7222 0.47 8uzb:A
47 7vw3:A 1052 269 0.0581 0.0656 0.2565 4.44e-11 5axw:A, 5czz:A, 7el1:A, 7eni:A, 7enr:A, 8jft:A, 8jg9:A, 8jg9:D
48 7vw3:A 1052 78 0.0219 0.0247 0.3333 0.50 5axw:A, 5czz:A, 7el1:A, 7eni:A, 7enr:A, 8jft:A, 8jg9:A, 8jg9:D
49 8x5v:A 892 399 0.0800 0.1065 0.2381 9.50e-09
50 8jtj:A 1042 317 0.0631 0.0720 0.2366 3.24e-05
51 8jtj:A 1042 18 0.0101 0.0115 0.6667 2.8
52 8jtr:A 1056 310 0.0640 0.0720 0.2452 9.86e-05
53 8jtr:A 1056 18 0.0101 0.0114 0.6667 2.8
54 8hnt:A 1000 123 0.0269 0.0320 0.2602 0.003
55 8wr4:B 1442 213 0.0497 0.0409 0.2770 0.016
56 6m0w:A 1032 375 0.0816 0.0940 0.2587 0.016 6m0v:A, 6m0x:A
57 8wmm:B 1212 213 0.0497 0.0487 0.2770 0.017 8iyq:A, 8wmh:A, 8wmm:A, 8wmn:A, 8wmn:B, 8wr4:A
58 6je4:O 1049 125 0.0261 0.0296 0.2480 0.15 8hj4:A, 8ja0:A, 6je9:C
59 6je4:O 1049 25 0.0118 0.0133 0.5600 6.0 8hj4:A, 8ja0:A, 6je9:C
60 6rj9:C 836 239 0.0497 0.0706 0.2469 0.25 6rjd:C
61 7v94:A 1076 107 0.0236 0.0260 0.2617 0.26 7v93:A
62 6jdq:A 1069 106 0.0227 0.0253 0.2547 0.28 6je4:A, 6je4:E, 6je4:K, 6je9:A
63 6kc7:A 963 106 0.0227 0.0280 0.2547 0.29
64 6rja:C 815 357 0.0682 0.0994 0.2269 0.62 6rja:F, 6rjg:C
65 6jfu:A 884 157 0.0303 0.0407 0.2293 0.66
66 6jfu:A 884 25 0.0118 0.0158 0.5600 6.1
67 7zjm:A 220 76 0.0210 0.1136 0.3289 1.9 6atg:B, 6atg:C
68 3x1l:D 331 126 0.0269 0.0967 0.2540 2.2 3x1l:C, 3x1l:E
69 2pla:A 343 89 0.0202 0.0700 0.2697 2.4 2pla:B
70 6bn2:A 393 72 0.0227 0.0687 0.3750 3.3
71 4gyi:A 339 115 0.0244 0.0855 0.2522 3.7
72 6stt:A 178 101 0.0227 0.1517 0.2673 4.5 6stt:B
73 8hnv:A 745 25 0.0118 0.0188 0.5600 4.7
74 4j2o:C 316 53 0.0143 0.0538 0.3208 5.2 4j2o:A, 4j2o:B, 4j2o:D, 4j2o:E, 4j2o:F
75 8ewy:A 1049 51 0.0177 0.0200 0.4118 5.4 6aah:A, 6aah:B, 6bbu:A, 6c7y:A, 6dbn:A, 5e1e:A, 5e1e:B, 4e4l:A, 4e4l:E, 4e4l:B, 4e4l:D, 4e4n:A, 4e4n:B, 4e5w:A, 4e5w:B, 4ehz:A, 4ehz:B, 4ehz:C, 4ehz:D, 4ei4:A, 4ei4:B, 6elr:A, 6elr:B, 8ewy:B, 3eyg:A, 3eyh:A, 4fk6:A, 4fk6:B, 6ggh:A, 6ggh:B, 5hx8:A, 5hx8:B, 6hzu:A, 6hzu:B, 4i5c:A, 4i5c:B, 4ivb:A, 4ivb:B, 4ivc:A, 4ivc:B, 4ivd:A, 4ivd:B, 4k6z:A, 4k77:A, 4k77:B, 5khw:A, 5khw:B, 5khx:A, 6n77:A, 6n77:B, 6n78:A, 6n79:A, 6n7a:A, 6n7a:B, 6n7b:A, 6n7c:A, 6n7c:B, 6n7d:A, 6rsb:A, 6rsb:B, 6rsc:A, 6rsc:B, 6rsd:A, 6rsd:B, 6rse:A, 6rse:B, 6rsh:A, 6rsh:B, 6sm8:A, 6sm8:B, 6smb:A, 6smb:B, 7t6f:A, 7t6f:B, 6tpe:A, 6tpe:B, 6tpf:A, 6tpf:B, 6w8l:A, 5wo4:A, 5wo4:B
76 6je3:A 858 25 0.0118 0.0163 0.5600 6.2
77 6efg:D 537 65 0.0160 0.0354 0.2923 7.9 6efg:A, 6efg:B
78 6l4t:7 188 58 0.0177 0.1117 0.3621 8.8 6l4u:7, 6ly5:E
79 2vjy:A 562 60 0.0152 0.0320 0.3000 9.6 6efg:E, 6efh:A, 6efh:B, 2vjy:B, 2vjy:C, 2vjy:D, 2vk4:A, 2vk4:B, 2vk4:C, 2vk4:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218