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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
DIYSRLLKDRIVLLSGEINDSVASSIVAQLLFLEAEDPEKDIGLYINSPGGVITSGLSIYDTMNFIRPDVSTICIGQAAS
MGAFLLSCGAKGKRFSLPHSRIMIHQPLGGAQGQASDIEIISNEILRLKGLMNSILAQNSGQSLEQIAKDTDRDFYMSAK
EAKEYGLIDKVLQ

The query sequence (length=173) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2zl2:A 174 173 1.0000 0.9943 1.0000 2.92e-125 2zl2:B, 2zl2:C, 2zl2:E, 2zl2:F, 2zl2:G, 2zl2:H, 2zl2:K, 2zl2:M, 2zl2:N, 2zl4:A, 2zl4:B, 2zl4:C, 2zl4:D, 2zl4:E, 2zl4:F, 2zl4:G, 2zl4:H, 2zl4:I, 2zl4:J, 2zl4:K, 2zl4:L, 2zl4:M, 2zl4:N
2 6wr2:N 197 172 0.7052 0.6193 0.7093 2.19e-92 2fzs:A, 2fzs:B, 2fzs:C, 2fzs:D, 2fzs:E, 2fzs:F, 2fzs:G, 2fzs:H, 2fzs:I, 2fzs:J, 2fzs:K, 2fzs:L, 2fzs:M, 2fzs:N, 3hln:E, 3hln:I, 3hln:Z, 3hln:J, 7mk5:A, 7mk5:B, 7mk5:C, 7mk5:D, 7mk5:E, 7mk5:F, 7mk5:G, 7mk5:H, 7mk5:I, 7mk5:J, 7mk5:K, 7mk5:L, 7mk5:M, 7mk5:N, 7mk5:O, 7mk5:P, 7mk5:Q, 7mk5:R, 7mk5:S, 7mk5:T, 7mk5:U, 7mk5:V, 7mk5:W, 7mk5:X, 7mk5:Y, 7mk5:Z, 7mk5:a, 7mk5:b, 3mt6:A, 3mt6:G, 3mt6:B, 3mt6:C, 3mt6:D, 3mt6:E, 3mt6:F, 3mt6:I, 3mt6:H, 3mt6:J, 3mt6:K, 3mt6:L, 3mt6:M, 3mt6:N, 3mt6:U, 3mt6:O, 3mt6:P, 3mt6:Q, 3mt6:R, 3mt6:S, 3mt6:T, 3mt6:V, 3mt6:W, 3mt6:X, 3mt6:Y, 3mt6:Z, 3mt6:a, 3mt6:b, 6nb1:A, 6nb1:G, 6nb1:B, 6nb1:C, 6nb1:D, 6nb1:E, 6nb1:F, 6nb1:H, 6nb1:I, 6nb1:J, 6nb1:K, 6nb1:L, 6nb1:M, 6nb1:N, 6ppe:A, 6ppe:G, 6ppe:B, 6ppe:C, 6ppe:D, 6ppe:E, 6ppe:F, 6ppe:H, 6ppe:N, 6ppe:I, 6ppe:J, 6ppe:K, 6ppe:L, 6ppe:M, 8szm:A, 8szm:G, 8szm:X, 8szm:Y, 8szm:Z, 8szm:a, 6wr2:H, 6wr2:I, 6wr2:J, 6wr2:K, 6wr2:L, 6wr2:M
3 8r05:A 191 172 0.6705 0.6073 0.6744 5.87e-89 8r05:B, 8r05:C, 8r05:D, 8r05:E, 8r05:F, 8r05:G, 8r05:H, 8r05:I, 8r05:J, 8r05:K, 8r05:L, 8r05:M, 8r05:N
4 8oll:A 192 172 0.6590 0.5938 0.6628 4.89e-86 5dl1:A, 5dl1:B, 5dl1:C, 5dl1:D, 5dl1:E, 5dl1:F, 5dl1:G, 5dl1:H, 5dl1:I, 5dl1:J, 5dl1:K, 5dl1:L, 5dl1:M, 5dl1:N, 8e71:A, 8e71:B, 8e71:C, 8e71:D, 8e71:E, 8e71:F, 8e71:G, 8e71:I, 8e71:K, 8e71:L, 8e71:M, 8e71:N, 8e71:S, 8e71:T, 8e7p:A, 8e7p:G, 8e7p:B, 8e7p:C, 8e7p:D, 8e7p:E, 8e7p:F, 8e7p:I, 8e7p:T, 8e7p:K, 8e7p:L, 8e7p:M, 8e7p:N, 8e7p:S, 8ef8:A, 8ef8:B, 8ef8:C, 8ef8:D, 8ef8:E, 8ef8:F, 8ef8:G, 8ef8:I, 8ef8:K, 8ef8:L, 8ef8:M, 8ef8:N, 8ef8:S, 8ef8:T, 6l3x:A, 6l3x:B, 6l3x:C, 6l3x:D, 6l3x:E, 6l3x:F, 6l3x:G, 6l3x:H, 6l3x:I, 6l3x:J, 6l3x:K, 6l3x:L, 6l3x:M, 6l3x:N, 6l40:E, 6l40:A, 6l40:B, 6l40:C, 6l40:D, 6l40:F, 6l40:G, 6l40:H, 6l40:I, 6l40:J, 6l40:K, 6l40:L, 6l40:M, 6l40:N, 6n80:A, 6n80:B, 6n80:C, 6n80:D, 6n80:E, 6n80:F, 6n80:G, 6n80:I, 6n80:K, 6n80:L, 6n80:M, 6n80:N, 6n80:S, 6n80:T, 8oll:B, 8oll:C, 8oll:D, 8oll:E, 8oll:F, 8oll:G, 8oll:H, 8oll:I, 8oll:J, 8oll:K, 8oll:L, 8oll:M, 8oll:N, 8oll:O, 8oll:P, 8oll:Q, 8oll:R, 8oll:S, 8oll:T, 8oll:U, 8oll:V, 8oll:W, 8oll:X, 8oll:Y, 8oll:Z, 8oll:a, 8oll:b, 6pka:A, 6pka:B, 6pka:C, 6pka:D, 6pka:E, 6pka:F, 6pka:G, 6pka:I, 6pka:K, 6pka:L, 6pka:M, 6pka:N, 6pka:S, 6pka:T, 6pmd:A, 6pmd:B, 6pmd:C, 6pmd:D, 6pmd:E, 6pmd:F, 6pmd:G, 6pmd:K, 6pmd:L, 6pmd:M, 6pmd:N, 6pmd:S, 6pmd:T, 6pmd:I, 8qyf:A, 8qyf:B, 8qyf:C, 8qyf:D, 8qyf:E, 8qyf:F, 8qyf:G, 8qyf:H, 8qyf:I, 8qyf:J, 8qyf:K, 8qyf:L, 8qyf:M, 8qyf:N, 8r03:A, 8r03:B, 8r03:C, 8r03:D, 8r03:E, 8r03:F, 8r03:G, 8r03:H, 8r03:I, 8r03:J, 8r03:K, 8r03:L, 8r03:M, 8r03:N, 3st9:B, 6ttz:A, 6ttz:G, 6ttz:B, 6ttz:C, 6ttz:D, 6ttz:E, 6ttz:F, 5vz2:A, 5vz2:B, 5vz2:C, 5vz2:D, 5vz2:E, 5vz2:F, 5vz2:G, 5vz2:I, 5vz2:K, 5vz2:L, 5vz2:M, 5vz2:N, 5vz2:S, 5vz2:T, 5w18:A, 5w18:B, 5w18:C, 5w18:D, 5w18:E, 5w18:F, 5w18:G, 5w18:I, 5w18:K, 5w18:L, 5w18:M, 5w18:N, 5w18:S, 5w18:T, 7wgs:A, 7wgs:G, 7wgs:B, 7wgs:C, 7wgs:D, 7wgs:E, 7wgs:F, 7wgs:H, 7wgs:N, 7wgs:I, 7wgs:J, 7wgs:K, 7wgs:L, 7wgs:M, 7wid:A, 7wid:G, 7wid:B, 7wid:C, 7wid:D, 7wid:E, 7wid:F, 7wid:H, 7wid:N, 7wid:I, 7wid:J, 7wid:K, 7wid:L, 7wid:M, 7xbz:A, 7xbz:B, 7xbz:C, 7xbz:D, 7xbz:E, 7xbz:F, 7xbz:G, 7xbz:H, 7xbz:I, 7xbz:J, 7xbz:K, 7xbz:L, 7xbz:M, 7xbz:N
5 3p2l:A 189 173 0.6763 0.6190 0.6763 5.69e-86 3p2l:B, 3p2l:C, 3p2l:D, 3p2l:E, 3p2l:F, 3p2l:G
6 7fep:C 189 172 0.6821 0.6243 0.6860 6.42e-86 7fep:D, 7fep:E, 7fep:F, 7fep:G, 7fep:H, 7fep:I, 7fep:J, 7fep:K, 7fep:L, 7fep:N, 7fep:A, 7fep:B, 7fep:M, 7fer:A, 7fer:B, 7fer:C, 7fer:D, 7fer:E, 7fer:F, 7fer:G, 7fer:H, 7fer:I, 7fer:J, 7fer:K, 7fer:L, 7fer:M, 7fer:N, 3kti:A, 3kti:B, 3kti:G, 3kti:E, 3kti:F, 3kti:C, 3kti:D, 3ktj:A, 3ktj:B, 3ktj:G, 3ktj:E, 3ktj:F, 3ktj:C, 3ktj:D, 3ktk:A, 3ktk:B, 3ktk:G, 3ktk:E, 3ktk:F, 3ktk:C, 3ktk:D, 3ktk:H, 3ktk:I, 3ktk:N, 3ktk:L, 3ktk:M, 3ktk:J, 3ktk:K, 7p80:B, 7p80:C, 7p80:F, 7p80:G, 7p81:A, 7p81:B, 7p81:C, 7p81:D, 7p81:E, 7p81:F, 7p81:G, 7p81:H, 7p81:I, 7p81:J, 7p81:K, 7p81:L, 7p81:M, 7p81:N, 7p81:O, 7p81:P, 7p81:Q, 7p81:R, 7p81:S, 7p81:T, 7p81:U, 7p81:V, 7p81:W, 7p81:X, 7p81:Y, 7p81:Z, 7p81:a, 7p81:b, 3tt7:A, 3tt7:B, 3tt7:C, 3tt7:D, 3tt7:E, 3tt7:F, 3tt7:G
7 7dfu:A 191 173 0.6590 0.5969 0.6590 2.01e-85 7dfu:B, 7dfu:C, 7dfu:D, 7dfu:E, 7dfu:F, 7dfu:G
8 6cfd:I 188 173 0.6532 0.6011 0.6532 6.06e-85 6cfd:A, 6cfd:B, 6cfd:C, 6cfd:D, 6cfd:E, 6cfd:F, 6cfd:G, 6cfd:K, 6cfd:L, 6cfd:M, 6cfd:N, 6cfd:S, 6cfd:T
9 8r04:G 180 173 0.6705 0.6444 0.6705 3.25e-84 8r04:A, 8r04:B, 8r04:C, 8r04:D, 8r04:E, 8r04:F, 8r04:H, 8r04:I, 8r04:J, 8r04:K, 8r04:L, 8r04:M, 8r04:N
10 5dkp:k 194 175 0.6647 0.5928 0.6571 9.68e-83 5dkp:A, 5dkp:G, 5dkp:B, 5dkp:C, 5dkp:D, 5dkp:E, 5dkp:F, 5dkp:H, 5dkp:N, 5dkp:I, 5dkp:J, 5dkp:K, 5dkp:L, 5dkp:M, 5dkp:a, 5dkp:g, 5dkp:b, 5dkp:c, 5dkp:d, 5dkp:e, 5dkp:f, 5dkp:h, 5dkp:n, 5dkp:i, 5dkp:j, 5dkp:l, 5dkp:m, 6nah:A, 6nah:G, 6nah:B, 6nah:C, 6nah:D, 6nah:E, 6nah:F, 6nah:H, 6nah:N, 6nah:I, 6nah:J, 6nah:K, 6nah:L, 6nah:M, 6nah:O, 6nah:U, 6nah:P, 6nah:Q, 6nah:R, 6nah:S, 6nah:T, 6nah:V, 6nah:b, 6nah:W, 6nah:X, 6nah:Y, 6nah:Z, 6nah:a, 8szn:V, 8szn:b, 8szn:W, 8szn:X, 8szn:Y, 8szn:Z, 8szn:a, 8szn:H, 8szn:N, 8szn:I, 8szn:J, 8szn:K, 8szn:L, 8szn:M, 6w9t:F
11 6hwm:E 195 172 0.6069 0.5385 0.6105 4.00e-78 6hwm:A, 6hwm:B, 6hwm:C, 6hwm:D, 6hwm:F, 6hwm:G, 6hwn:A, 6hwn:B, 6hwn:C, 6hwn:D, 6hwn:E, 6hwn:F, 6hwn:G
12 8dla:A 203 172 0.6127 0.5222 0.6163 4.32e-76 8dla:C, 8dla:B, 8dla:D, 8dla:G, 8dla:I, 8dla:M
13 1tg6:E 196 172 0.5780 0.5102 0.5814 2.08e-69 6bba:A, 6bba:G, 6bba:B, 6bba:C, 6bba:D, 6bba:E, 6bba:F, 6dl7:A, 6dl7:G, 6dl7:B, 6dl7:C, 6dl7:D, 6dl7:E, 6dl7:F, 6h23:A, 6h23:B, 6h23:C, 6h23:D, 6h23:E, 6h23:F, 6h23:G, 6h23:H, 6h23:N, 6h23:I, 6h23:J, 6h23:K, 6h23:L, 6h23:M, 8hgk:A, 8hgk:G, 8hgk:B, 8hgk:C, 8hgk:D, 8hgk:E, 8hgk:F, 8hgk:H, 8hgk:N, 8hgk:I, 8hgk:J, 8hgk:K, 8hgk:L, 8hgk:M, 8i7x:B, 8i7x:C, 8i7x:A, 8i7x:D, 8i7x:E, 8i7x:F, 8i7x:G, 8i7x:H, 8i7x:N, 8i7x:I, 8i7x:J, 8i7x:K, 8i7x:L, 8i7x:M, 1tg6:A, 1tg6:B, 1tg6:C, 1tg6:D, 1tg6:F, 1tg6:G, 7uvm:A, 7uvm:G, 7uvm:B, 7uvm:C, 7uvm:D, 7uvm:E, 7uvm:F, 7uvn:A, 7uvn:G, 7uvn:B, 7uvn:C, 7uvn:D, 7uvn:E, 7uvn:F, 7uvr:A, 7uvr:G, 7uvr:B, 7uvr:C, 7uvr:D, 7uvr:E, 7uvr:F, 7uvu:A, 7uvu:G, 7uvu:B, 7uvu:C, 7uvu:D, 7uvu:E, 7uvu:F, 7uw0:A, 7uw0:G, 7uw0:B, 7uw0:C, 7uw0:D, 7uw0:E, 7uw0:F, 7vp9:A, 7vp9:G, 7vp9:B, 7vp9:C, 7vp9:D, 7vp9:E, 7vp9:F, 7vp9:H, 7vp9:N, 7vp9:I, 7vp9:J, 7vp9:K, 7vp9:L, 7vp9:M, 8w7c:A, 8w7c:F, 8w7c:B, 8w7c:C, 8w7c:D, 8w7c:E, 8w7c:G, 8w7e:A, 8w7e:B, 8w7e:G, 8w7e:C, 8w7e:D, 8w7e:H, 8w7e:E, 8w7e:F, 8w7e:K, 8w7e:M, 8w7e:I, 8w7e:N, 8w7e:J, 8w7e:L, 7wh5:A, 7wh5:G, 7wh5:B, 7wh5:C, 7wh5:D, 7wh5:E, 7wh5:F, 7wh5:H, 7wh5:N, 7wh5:I, 7wh5:J, 7wh5:K, 7wh5:L, 7wh5:M, 8ylb:A, 8ylb:G, 8ylb:B, 8ylb:C, 8ylb:D, 8ylb:E, 8ylb:F, 8ylb:H, 8ylb:N, 8ylb:I, 8ylb:J, 8ylb:K, 8ylb:L, 8ylb:M
14 3q7h:B 193 173 0.5723 0.5130 0.5723 1.06e-68 3q7h:A, 3q7h:C, 3q7h:D, 3q7h:E, 3q7h:F, 3q7h:G, 3q7h:H, 3q7h:I, 3q7h:J, 3q7h:K, 3q7h:L, 3q7h:M, 3q7h:N
15 8xop:A 178 171 0.5491 0.5337 0.5556 8.54e-66 8xop:B, 8xop:C, 8xop:D, 8xop:E, 8xop:F, 8xop:G
16 1y7o:B 178 172 0.5202 0.5056 0.5233 1.16e-64 1y7o:A, 1y7o:C, 1y7o:E, 1y7o:F, 1y7o:G
17 5dzk:N 179 171 0.4971 0.4804 0.5029 5.13e-62 5dzk:H, 5dzk:I, 5dzk:J, 5dzk:K, 5dzk:L, 5dzk:M, 5dzk:h, 5dzk:i, 5dzk:j, 5dzk:k, 5dzk:l, 5dzk:m, 5dzk:n, 6iw7:B, 6iw7:K, 6iw7:M, 6iw7:D, 6iw7:I, 6iw7:N, 6iw7:G, 4u0g:H, 4u0g:I, 4u0g:J, 4u0g:K, 4u0g:L, 4u0g:M, 4u0g:N, 4u0g:V, 4u0g:W, 4u0g:X, 4u0g:Y, 4u0g:Z, 4u0g:a, 4u0g:b, 6vgq:N, 6vgq:H, 6vgq:I, 6vgq:J, 6vgq:K, 6vgq:L, 6vgq:M, 7x8x:K, 7x8x:B, 7x8x:M, 7x8x:D, 7x8x:I, 7x8x:G, 7x8x:N, 7x8x:W, 7x8x:P, 7x8x:Y, 7x8x:R, 7x8x:U, 7x8x:b, 7x8x:Z
18 5dzk:B 200 173 0.5145 0.4450 0.5145 6.94e-56 5dzk:A, 5dzk:C, 5dzk:D, 5dzk:E, 5dzk:F, 5dzk:G, 5dzk:a, 5dzk:b, 5dzk:c, 5dzk:d, 5dzk:e, 5dzk:f, 5dzk:g, 6iw7:A, 6iw7:C, 6iw7:F, 6iw7:H, 6iw7:J, 6iw7:L, 6iw7:E, 4u0g:A, 4u0g:B, 4u0g:G, 4u0g:C, 4u0g:D, 4u0g:E, 4u0g:F, 4u0g:O, 4u0g:P, 4u0g:Q, 4u0g:R, 4u0g:S, 4u0g:T, 4u0g:U, 6vgn:A, 6vgn:B, 6vgn:G, 6vgn:F, 6vgn:E, 6vgn:D, 6vgn:C, 7x8x:J, 7x8x:A, 7x8x:F, 7x8x:C, 7x8x:H, 7x8x:E, 7x8x:L, 7x8x:V, 7x8x:O, 7x8x:S, 7x8x:Q, 7x8x:T, 7x8x:a, 7x8x:X
19 8xop:H 176 173 0.4682 0.4602 0.4682 1.77e-54 8xop:I, 8xop:J, 8xop:K, 8xop:L, 8xop:M, 8xop:N
20 4fnb:A 232 30 0.0867 0.0647 0.5000 0.022 4fn8:A, 4fnd:A
21 4eht:A 268 64 0.1272 0.0821 0.3438 0.33 4eht:B, 4ehu:A, 4ehu:B, 4eia:A
22 4rel:A 446 89 0.1387 0.0538 0.2697 1.1 4rem:A, 4ren:A, 4whm:A
23 3hda:P 382 67 0.1156 0.0524 0.2985 1.8 3hbv:P
24 4mgz:E 632 33 0.0751 0.0206 0.3939 3.2 3cf6:E, 4mgi:E, 4mgk:E, 4mgy:E, 4mh0:E
25 6fyx:I 188 54 0.0925 0.0851 0.2963 4.6 6fyy:I, 6gsm:I, 6gsn:I, 8i7j:I, 5it7:I, 5it9:I, 3j80:I, 3j81:I, 3jam:I, 3jap:I, 8rw1:I, 8s8d:I, 8s8e:I, 8s8f:I, 8s8g:I, 8s8h:I, 8s8i:I, 8s8j:I, 6uz7:I
26 8kgf:A 1261 58 0.1156 0.0159 0.3448 7.7
27 2z6i:B 321 40 0.0694 0.0374 0.3000 8.7 2z6i:A, 2z6j:A, 2z6j:B
28 3mmr:A 308 80 0.1503 0.0844 0.3250 8.7 3sl0:A, 3sl1:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218