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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
DIPQPIRGDKGATVKIPRNIERDRQNPDMLVPPETDHGTVSNMKFSFSDTHNRLEKGGYAREVTVRELPISENLASVNMR
LKPGAIRELHWHKEAEWAYMIYGSARVTIVDEKGRSFIDDVGEGDLFYFPSGLPHSIQALEEGAEFLLVFDDGSFSENST
FQLTDWLAHTPKEVIAANFGVTKEEISNLPGKEKYIFENQLPGSLKDDIVEGPNGEVPYPFTYRLLEQEPIESEGGKVYI
ADSTNFKVSKTIASALVTVEPGAMRELHWHPNTHEWQYYISGKARMTVFASDGHARTFNYQAGDVGYVPFAMGHYVENIG
DEPLVFLEIFKDDHYADVSLNQWLAMLPETFVQAHLDLGKDFTDVLSKEKHPVVKKK

The query sequence (length=377) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5vg3:A 382 377 0.9973 0.9843 0.9973 0.0 5hi0:A, 1j58:A, 1l3j:A, 4met:A, 4met:B, 4met:C, 4met:D, 3s0m:A, 6tzp:A, 6ufi:A, 1uw8:A, 2uy8:A, 2uy9:A, 2uya:A, 2uyb:A, 2v09:A, 5vg3:B, 5vg3:C
2 6l9i:A 338 338 0.5305 0.5917 0.5917 2.63e-153 6l9i:B, 6l9i:C, 6l9i:D, 6l9i:E, 6l9i:F
3 2vqa:A 356 326 0.3607 0.3820 0.4172 4.24e-86 2vqa:B, 2vqa:C
4 2vqa:A 356 139 0.1273 0.1348 0.3453 8.20e-22 2vqa:B, 2vqa:C
5 2vqa:A 356 156 0.1273 0.1348 0.3077 7.66e-19 2vqa:B, 2vqa:C
6 3fz3:A 388 102 0.0822 0.0799 0.3039 3.70e-06 3fz3:D, 3fz3:E
7 3fz3:A 388 122 0.0716 0.0696 0.2213 0.81 3fz3:D, 3fz3:E
8 3fz3:A 388 28 0.0318 0.0309 0.4286 3.8 3fz3:D, 3fz3:E
9 3fz3:B 410 102 0.0822 0.0756 0.3039 3.96e-06 3fz3:C, 3fz3:F
10 3fz3:B 410 122 0.0716 0.0659 0.2213 0.82 3fz3:C, 3fz3:F
11 3fz3:B 410 28 0.0318 0.0293 0.4286 4.0 3fz3:C, 3fz3:F
12 4lum:A 190 68 0.0637 0.1263 0.3529 9.51e-06 2gc0:A, 2gc0:B, 2gc1:A, 2gc1:B, 2gc2:A, 2gc2:B, 2gc3:A, 2gc3:B, 4lta:A, 4lta:B, 4luk:A, 4lul:A, 4lul:B, 4lum:B, 1qxr:A, 1qxr:B, 1qy4:A, 1qy4:B, 1x7n:A, 1x82:A
13 1j3p:A 187 72 0.0584 0.1176 0.3056 2.61e-04 1j3q:A, 1j3q:B, 1j3r:A, 1j3r:B
14 7zvy:A 112 91 0.0716 0.2411 0.2967 0.002
15 7zvm:A 104 91 0.0637 0.2308 0.2637 0.004
16 1o4t:A 115 76 0.0610 0.2000 0.3026 0.043 1o4t:B
17 4dnr:A 1031 55 0.0451 0.0165 0.3091 0.29 3k0i:A, 7kf6:A, 7kf6:B, 7kf6:C, 7kf7:B, 7kf8:B, 7kf8:C, 3t53:A
18 2evx:A 382 92 0.0610 0.0602 0.2500 0.32
19 4yrd:B 346 69 0.0531 0.0578 0.2899 0.43 3vhr:A, 4yrd:A
20 3st7:A 369 69 0.0531 0.0542 0.2899 0.45 2zkl:A
21 3ht2:A 143 95 0.0663 0.1748 0.2632 0.74 3ht2:C
22 2d5f:B 385 63 0.0451 0.0442 0.2698 0.82 2d5f:A, 2d5h:A, 2d5h:C, 2d5h:D, 2d5h:E, 2d5h:F, 1od5:A, 1od5:B
23 2d40:A 289 82 0.0637 0.0830 0.2927 0.88 2d40:B, 2d40:C, 2d40:D
24 3h50:A 114 66 0.0451 0.1491 0.2576 1.1
25 5cu1:A 197 68 0.0477 0.0914 0.2647 2.7
26 6yxa:A 536 43 0.0451 0.0317 0.3953 4.9 8acu:A, 8acu:B
27 6htq:x 341 43 0.0451 0.0499 0.3953 5.3
28 3fe5:A 283 56 0.0398 0.0530 0.2679 5.5
29 6km8:A 345 99 0.0557 0.0609 0.2121 5.8
30 5fok:A 656 51 0.0477 0.0274 0.3529 8.7 5fok:B
31 5wxu:B 400 61 0.0451 0.0425 0.2787 8.9 5wxu:A, 5wxu:D, 5wxu:F, 5wxu:C, 5wxu:E
32 3qyy:B 156 63 0.0504 0.1218 0.3016 9.2 3qyy:A
33 5dn6:A 505 180 0.1061 0.0792 0.2222 9.9 5dn6:B, 5dn6:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218