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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
DIKISVVVPTYNTELEGLKNLMASIDKQTMNPDEYELVFVDDGSTTDTYERLQEFAETRPNMTVKQIENSGWGSRPRNIA
TKMAKGEYILYLDHDDTVFPETFERVYNFGKENNLDVVSGKEVRTNGWSWGWKQFSENNPHAEEMGIECLLPMTPHKFYK
REFLLENDITFDDGARVLWEAVYFNSKAFIHGAKVGILADYPTYYWIATGANSFGRDPHEKWNQINKLFNFFKDNIKEQR
DLDFMLTHWYRSRVLGILGQWLLKNNNERIDIEFNYAKKLAEELIPAYISENLDKNNQVKDYLLRQGDLDSLKKLAQIDA
GITALSYVEDAYFKEDKLFFKTSTKMTYEDKEDFFIEKTADRMERILPEEIKSKLPKEFFDYSDDLAEFTYEPSIKGRNS
RATWKIDGSTSNVEVVNKKANLYKIEGEMSFSVQINDYILDAADKKQPWDIATRFTGLGYTSHRALTIGKILIKTALINN
KTMIVYKNASGLISLDVGSSVRSIVEDSGVKREQILIDKTSGKVTIPLNEIHVFGESLIEGNAELKPVGISDADPINVKA
KLIGEANKARVEVLLGDEKLSGEYHLVTNIQGKKDKQQIKITL

The query sequence (length=603) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8bz6:A 606 606 0.9983 0.9934 0.9934 0.0 8bz6:B, 8bz6:C, 8bz6:D, 8bz6:E, 8bz6:F, 8bz7:A, 8bz7:B, 8bz7:C, 8bz7:D, 8bz7:E, 8bz7:F, 8bz8:A, 8bz8:B, 8bz8:C, 8bz8:D, 8bz8:E, 8bz8:F
2 5tze:C 349 205 0.1128 0.1948 0.3317 1.14e-27 5tze:E, 5tzj:C, 5tzj:A, 5tzk:C
3 6h4f:B 318 256 0.1294 0.2453 0.3047 7.54e-23 6h1j:B, 6h21:A, 6h21:B, 6h21:C, 6h2n:A, 6h2n:B, 6h2n:C, 6h4f:C, 6h4f:F, 6h4f:O, 6h4f:P, 6h4f:E, 6h4f:G, 6h4f:Q, 6h4f:A, 6h4f:D, 6h4f:H, 6h4f:I, 6h4m:B, 6h4m:C, 6h4m:F, 6h4m:O, 6h4m:P, 6h4m:E, 6h4m:G, 6h4m:Q, 6h4m:A, 6h4m:D, 6h4m:H, 6h4m:I, 6hnq:B, 6hnq:C, 6hnq:F, 6hnq:O, 6hnq:P, 6hnq:E, 6hnq:G, 6hnq:Q, 6hnq:A, 6hnq:D, 6hnq:H, 6hnq:I
4 2z86:C 603 136 0.0663 0.0663 0.2941 7.72e-08 2z86:A, 2z86:B, 2z86:D, 2z87:A, 2z87:B
5 2z86:C 603 95 0.0448 0.0448 0.2842 0.002 2z86:A, 2z86:B, 2z86:D, 2z87:A, 2z87:B
6 5mlz:A 355 112 0.0597 0.1014 0.3214 2.92e-07 5mm0:A, 5mm1:A
7 6yv8:A 346 96 0.0514 0.0896 0.3229 2.52e-05 6yv8:B, 6yv9:A, 6yv9:B
8 8viw:B 545 107 0.0498 0.0550 0.2804 0.005 8vh7:A, 8vh7:B, 8vh8:A, 8vh8:B, 8vh8:C, 8vh8:D, 8viw:A, 8viw:D, 8viw:C
9 5eke:C 307 137 0.0547 0.1075 0.2409 0.016 5eke:A, 5eke:B, 5eke:D, 5ekp:C, 5ekp:A, 5ekp:B, 5ekp:D
10 1h7q:A 240 107 0.0514 0.1292 0.2897 0.053 1h7l:A, 1qgq:A, 1qgs:A
11 4r5e:A 343 102 0.0547 0.0962 0.3235 4.6
12 4l9y:C 316 86 0.0398 0.0759 0.2791 5.1 4l9y:A, 4l9y:B, 4l9y:D, 4l9y:E, 4l9y:F, 4l9z:A, 4l9z:B, 4l9z:C, 4l9z:D, 4l9z:E, 4l9z:F
13 7avk:A 83 52 0.0265 0.1928 0.3077 5.3 7avk:B
14 4iuh:A 143 75 0.0381 0.1608 0.3067 5.4 4iuh:B, 4iuk:A, 4iuk:B
15 8tj5:0 1246 65 0.0398 0.0193 0.3692 6.2 8tj5:Y
16 4c2u:A 658 64 0.0332 0.0304 0.3125 9.4 4c2t:A, 4c2t:B, 4c2t:C, 4c2t:D, 4c2u:D, 4c30:I, 4c30:D
17 4c30:F 632 64 0.0332 0.0316 0.3125 9.9 4c30:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218