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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
DHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESA
KQAKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLY

The query sequence (length=120) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 9exw:A 148 132 0.9833 0.7973 0.8939 4.54e-80 9exw:B, 9exx:A, 9exx:B, 9exy:A, 7lmt:A, 7lmt:H, 7lmt:B, 7lmt:C, 7lmt:D, 7lmt:E, 7lmt:F, 7lmt:G, 7mdn:A, 7mdn:H, 7mdn:B, 7mdn:C, 7mdn:D, 7mdn:E, 7mdn:F, 7mdn:G, 6ue6:A, 6ue6:B, 6ue6:D, 6ue6:E, 6ue6:G, 6ue6:H, 5vc8:A, 7vln:B, 6xcg:A, 6xcg:B, 6xcg:C
2 9exy:B 135 124 0.9417 0.8370 0.9113 1.19e-77 6ue6:C, 6ue6:F
3 6g2b:A 123 119 0.5250 0.5122 0.5294 6.54e-44 6g24:A, 6g25:A, 6g27:A, 6g29:A, 6g2c:A, 6g2e:A, 6g2f:A, 6g2o:A
4 6kcp:B 84 45 0.1500 0.2143 0.4000 3.00e-06 6kco:O, 6kco:F, 6kco:M, 6kco:E, 6kco:P, 6kco:B, 6kco:H, 6kco:D, 6kco:I, 6kco:N, 6kco:G, 6kco:J, 6kco:L, 6kco:A, 6kco:C, 6kco:K
5 5xsk:A 90 62 0.2000 0.2667 0.3871 1.65e-05
6 5ciu:B 121 47 0.1500 0.1488 0.3830 1.67e-05
7 5nrr:B 137 48 0.1500 0.1314 0.3750 3.38e-05 5ciu:A, 5nr3:A, 5nr3:B, 5nrr:A, 5nrs:A, 5nrs:B, 5nrv:D, 5nrv:A, 5nv0:A, 5nv0:B, 5nv2:A, 5nv2:B, 5nv7:A, 5nv7:B, 6r3e:A
8 6iit:B 100 62 0.1917 0.2300 0.3710 2.67e-04 6iiq:A, 6iiq:B, 6iir:A, 6iir:B, 6iis:B, 6iis:A, 6iit:A
9 4n4g:A 209 49 0.1500 0.0861 0.3673 0.005 4n4h:A, 4n4i:A, 4ns5:A
10 3qj6:A 90 103 0.2167 0.2889 0.2524 0.017 3qby:B
11 8cbn:L 86 25 0.0917 0.1279 0.4400 0.079 8cbn:K, 8cbq:K, 8pc5:K, 8pc6:L, 8pc6:K, 8peo:K, 8pep:L, 8pep:K, 6s01:K
12 5b73:A 313 52 0.1417 0.0543 0.3269 0.27 4cos:A, 7cwh:B, 5y1z:C, 5y1z:D
13 7lh9:C 107 74 0.1667 0.1869 0.2703 0.72 4z02:B
14 3mo8:A 127 21 0.0917 0.0866 0.5238 0.87 5c6s:A, 2x4w:A, 2x4x:A, 2x4x:C, 2x4x:E, 2x4x:G, 2x4y:A, 2x4y:C, 2x4y:E, 2x4y:G, 2x4y:I, 2x4y:K, 2x4y:M, 2x4y:O
15 6fyx:i 121 53 0.1333 0.1322 0.3019 2.0 8cah:i, 8cas:A, 6fyy:i, 6gsm:i, 6gsn:i, 3j80:i, 3j81:i, 3jam:i, 3jap:i, 8rw1:i, 8s8d:i, 8s8e:i, 8s8f:i, 8s8g:i, 8s8h:i, 8s8i:i, 8s8j:i, 4uer:0, 6zce:i, 6zu9:A
16 8sky:B 303 61 0.1333 0.0528 0.2623 2.4 8sky:A, 8sut:A, 8sut:B, 8suu:A, 8suu:B
17 1ker:B 347 63 0.1583 0.0548 0.3016 4.3 1kep:A, 1kep:B, 1ker:A, 1ket:A, 1ket:B, 1oc2:A, 1oc2:B
18 4z02:A 119 20 0.0833 0.0840 0.5000 6.0 7lh9:B
19 1eje:A 192 57 0.1167 0.0729 0.2456 6.3
20 6ck7:A 172 37 0.1000 0.0698 0.3243 7.5 6ck7:B, 6ck7:C, 6ck7:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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