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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
DHFNYQNDGRLFVEGLPVEQVVKKTGTPAYIYSRATIERHWQAFDSAAGHPHLICYAVKANSNLAVLNLMARMGSGFDIV
SVGELMRVIQAGGDPKKIVFSGVGKTEIEISAALQANIMCFNVESISELYRINSVAKALNVKAPISIRINPENKFGIEIE
QALDVYKIASDLEFLEIKGVDCHIGSQLTEIAPFIEALDKLLILIDLLAEKITISHLDLGGGLGVPYDDETPPEPAEYMT
AIINRMGRSLKLIFEPGRAIMANAGVLVTKVEFLKLNDKNFAIVDAAMNDLIRPALYSAWQNIIPLNTDYQDGQDRPVRS
YDIVGPICETGDFLGKERQLALAEGDYLVIRSTGAYGSTMSSNYNSRCRAAEILVDGEKAFIVREREELKDLWRGEHILP
IHH

The query sequence (length=403) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4xg1:B 418 419 0.9926 0.9569 0.9547 0.0 4xg1:C, 4xg1:D
2 4xg1:A 393 403 0.9653 0.9898 0.9653 0.0
3 3c5q:A 394 397 0.4169 0.4264 0.4232 1.45e-92 2qgh:A
4 1tuf:A 434 429 0.4218 0.3917 0.3963 2.46e-89 1tuf:B, 1twi:A, 1twi:B, 1twi:C, 1twi:D
5 6n2a:A 422 422 0.3499 0.3341 0.3341 6.89e-62 6n2a:B, 6n2f:B, 6n2f:A
6 2yxx:A 385 397 0.3251 0.3403 0.3300 5.07e-60
7 1knw:A 421 408 0.3052 0.2922 0.3015 1.66e-46 1ko0:A
8 7ru7:A 412 370 0.2680 0.2621 0.2919 9.02e-39 2j66:A
9 1hkv:A 446 424 0.2878 0.2601 0.2736 9.24e-38 1hkv:B
10 5x7m:A 443 423 0.2829 0.2573 0.2695 1.55e-31 5x7m:B, 5x7n:A, 5x7n:B
11 6knh:C 384 370 0.2506 0.2630 0.2730 6.11e-30 6knh:A, 6knh:B, 6kni:A, 6kni:B, 6kni:C, 6knk:A, 6knk:B, 6knk:C
12 8d4i:A 462 427 0.2655 0.2316 0.2506 8.75e-29 8d2y:A, 8d4i:C, 8d5d:A, 8d5d:B, 8d5r:A, 8d5r:B, 8d88:A, 8d88:B
13 5gjo:A 385 386 0.2655 0.2779 0.2772 1.98e-28 5gjn:A, 5gjo:B, 5gjp:A
14 7kh2:D 415 406 0.2531 0.2458 0.2512 1.13e-25 7kh2:A, 7kh2:B, 7kh2:C
15 2plj:A 376 375 0.2432 0.2606 0.2613 1.02e-22 2plj:B, 2plk:A, 2plk:B
16 1f3t:B 381 398 0.2531 0.2677 0.2563 4.78e-20 1f3t:A, 1f3t:C, 1f3t:D, 1njj:A, 1njj:B, 1njj:C, 1njj:D, 1qu4:A, 1qu4:B, 1qu4:C, 1qu4:D, 1szr:C, 1szr:D, 1szr:A, 1szr:B, 2tod:A, 2tod:B, 2tod:C, 2tod:D
17 2oo0:A 419 335 0.2084 0.2005 0.2507 3.51e-17 5bwa:A, 7odc:A, 2on3:A, 2on3:B, 2oo0:B, 7s3f:A, 7s3f:B, 7s3g:A, 7s3g:B, 7u6p:A, 7u6p:B, 7u6u:A, 7u6u:B, 4zgy:A
18 2nv9:B 372 344 0.2184 0.2366 0.2558 1.40e-15 2nv9:A, 2nv9:C, 2nv9:D, 2nv9:E, 2nv9:F, 2nv9:G, 2nv9:H, 2nva:A, 2nva:B, 2nva:C, 2nva:D, 2nva:E, 2nva:F, 2nva:G, 2nva:H
19 3nzq:A 628 309 0.1811 0.1162 0.2362 4.49e-09 3nzq:B
20 3nzp:B 591 282 0.1712 0.1168 0.2447 1.09e-08 3nzp:A
21 3n2o:A 630 264 0.1613 0.1032 0.2462 3.43e-07 3n2o:B, 3n2o:C, 3n2o:D
22 6cdf:A 333 83 0.0620 0.0751 0.3012 0.69 8ari:A, 8ari:G, 8ari:D, 8ari:F, 8ari:E, 8ari:J, 8ari:H, 8ari:K, 8ari:I, 8ari:P, 8ari:L, 8ari:M, 8ari:N, 8ari:T, 8ari:O, 8ari:Q, 8ari:R, 8ari:U, 8ari:S, 8ari:X, 8ari:B, 8ari:C, 8ari:V, 8ari:W, 6cdr:A, 1hku:A, 1hl3:A, 2hu2:A, 7kwm:A, 4lce:A, 1mx3:A, 4u6q:A, 4u6s:A, 6v89:A, 6v8a:A
23 8ati:A 330 83 0.0596 0.0727 0.2892 2.3 8ati:B, 8ati:C, 8ati:D, 4lcj:A, 4lcj:B, 4lcj:C, 4lcj:D, 4lcj:E, 4lcj:F, 4lcj:G, 4lcj:H, 2ome:A, 2ome:B, 2ome:C, 2ome:D, 2ome:E, 2ome:F, 2ome:G, 2ome:H, 6wkw:D, 6wkw:C, 6wkw:B, 6wkw:A
24 3j6b:C 249 56 0.0447 0.0723 0.3214 5.1 5mrc:C, 5mre:C, 5mrf:C
25 2e7u:A 424 65 0.0571 0.0542 0.3538 6.5
26 7x0b:B 301 24 0.0273 0.0365 0.4583 6.6 7wzv:A, 7wzv:B, 7wzx:A, 7x0b:A
27 5nof:A 325 111 0.0720 0.0892 0.2613 7.8 5nof:B
28 3n29:A 371 127 0.0844 0.0916 0.2677 8.3 3n29:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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