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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
DDWRCARSMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQCGKTEVNYTQLVDLHARYAECGLRILAFPCNQFGKQEPGS
NEEIKEFAAGYNVKFDMFSKICVNGDDAHPLWKWMKIQPKGKGILGNAIKWNFTKFLIDKNGCVVKRYGPMEEPLVIEKD
LPHYF

The query sequence (length=165) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7u4m:A 171 165 1.0000 0.9649 1.0000 1.72e-125 5h5q:A, 5h5r:A, 5h5s:A, 6hkq:A, 7u4i:A, 7u4i:B, 7u4k:A, 7u4l:A, 7u4l:B, 7u4l:D, 7u4n:A, 7u4n:B
2 2wgr:A 163 155 0.5152 0.5215 0.5484 6.11e-54
3 2p5r:A 164 157 0.4364 0.4390 0.4586 1.16e-47
4 8w7y:A 474 71 0.1030 0.0359 0.2394 0.31
5 1xzo:A 172 92 0.1455 0.1395 0.2609 0.48 1xzo:B
6 1jba:A 189 52 0.0848 0.0741 0.2692 0.79
7 2jul:A 181 40 0.0848 0.0773 0.3500 2.4 2e6w:A
8 8c8x:D 186 55 0.1030 0.0914 0.3091 2.5 8c8y:D, 8c8z:D, 8c90:D, 8c91:D, 8c92:D, 8c94:D, 8c96:D, 6gc6:D, 6gc7:D, 8j1z:d, 7ode:L
9 2yp6:A 143 53 0.0788 0.0909 0.2453 3.0 2yp6:B, 2yp6:C, 2yp6:D
10 6u5w:A 1435 49 0.1030 0.0118 0.3469 6.7
11 8sfn:A 1302 36 0.0848 0.0108 0.3889 8.0 8sfh:A, 8sfl:A, 5xh6:A, 5xh7:A
12 8sfo:A 1240 36 0.0848 0.0113 0.3889 8.2 8sfi:A, 8sfp:A, 8sfq:A, 8sfr:A
13 8a3l:d 209 54 0.0970 0.0766 0.2963 9.0 7abz:C, 7ac7:C, 7acj:C, 7acr:C, 5ady:D, 5afi:D, 5aka:D, 8akn:d, 8am9:d, 8ana:d, 8ap4:d, 9ax7:d, 9ax8:4, 8aye:d, 8b0x:d, 7b5k:D, 8b7y:L, 3bbx:D, 8bf7:B, 8bge:B, 8bgh:B, 8bh4:B, 8bhj:B, 8bhl:B, 8bhn:B, 8bhp:B, 8bil:B, 8bim:B, 7bl2:D, 7bl3:D, 7bl4:D, 7bl5:D, 7bl6:D, 6bu8:05, 7bv8:D, 6by1:CD, 6by1:DD, 6c4h:D, 6c4i:D, 8cam:d, 8ceu:d, 8cgd:d, 8cgk:d, 8cgv:d, 9cg5:d, 9cg6:d, 9cg7:d, 7cpj:D, 4csu:D, 7d6z:D, 7d80:c, 6dnc:G, 8e30:N, 8e32:N, 8e33:N, 8e35:N, 8e36:N, 8e3l:N, 8e3m:N, 8e3o:N, 8e41:N, 8e42:N, 8e43:N, 8e44:N, 8e45:N, 8e46:N, 8e47:N, 8e48:N, 8e49:N, 8eiu:d, 8ekc:D, 8emm:d, 6enf:D, 6enj:D, 6enu:D, 9fbv:d, 8fiz:BE, 8fto:d, 8fzd:D, 8fze:D, 8fzf:D, 8fzg:D, 8fzh:D, 8fzi:D, 8fzj:D, 8g2u:D, 8g31:D, 8g34:D, 8g38:D, 8g6w:d, 8g6x:d, 8g6y:d, 8g7p:D, 8g7q:D, 8g7r:D, 8g7s:D, 5gad:D, 5gae:D, 5gaf:D, 5gag:D, 5gah:D, 6gbz:D, 6gc0:D, 6gc4:D, 6gc8:D, 6gwt:D, 6gxm:D, 6gxn:D, 6gxo:D, 6gxp:D, 6h4n:D, 5h5u:D, 6h58:D, 6h58:DD, 6hrm:C, 8hsp:d, 8htz:d, 8hu1:d, 6i0y:D, 6i7v:DD, 6i7v:CD, 8ifb:d, 8ifc:d, 5iqr:C, 5it8:CD, 5it8:DD, 3iy9:C, 2j28:D, 3j5l:D, 5j5b:CD, 5j5b:DD, 3j7z:D, 5j7l:CD, 5j7l:DD, 3j8g:D, 5j88:CD, 5j88:DD, 5j8a:CD, 5j8a:DD, 3j9y:D, 3j9z:LX, 5j91:CD, 5j91:DD, 3ja1:LE, 3jbu:d, 3jbv:d, 3jcd:D, 3jce:D, 3jcj:C, 3jcn:D, 5jc9:CD, 5jc9:DD, 7jss:c, 7jsw:c, 7jsz:c, 5jte:BD, 7jt1:c, 7jt2:c, 7jt3:c, 5ju8:BD, 7k00:d, 7k50:c, 7k51:c, 7k52:c, 7k53:c, 7k54:c, 7k55:c, 5kcr:1E, 5kcs:1E, 5kps:C, 5kpv:B, 5kpw:B, 5kpx:B, 5l3p:E, 6lkq:V, 7lv0:c, 7lvk:L, 5lza:D, 5lzb:D, 5lzc:D, 5lzd:D, 5lze:D, 5lzf:D, 7m5d:C, 5mdv:C, 5mdw:C, 5mdy:C, 5mdz:C, 5mgp:D, 7n1p:LC, 7n2c:LC, 7n2u:LC, 7n2v:LC, 7n30:LC, 7n31:LC, 7nbu:d, 5nco:D, 5np6:b, 7nso:D, 7nsp:D, 7nsq:D, 5nwy:Q, 7nwt:C, 7nww:D, 7o19:BD, 7o1a:BD, 7o1c:BD, 5o2r:D, 6o9j:D, 6o9k:4, 6ofx:c, 6og7:c, 6ogf:c, 6ogg:c, 6ogi:c, 7oif:D, 7oig:D, 7oii:D, 7oiz:d, 7oj0:d, 6om6:C, 6ore:C, 6orl:C, 6osk:C, 6osq:C, 6ost:C, 6ot3:C, 7ot5:D, 7otc:D, 6ouo:C, 8p16:C, 8p17:C, 8p18:C, 7p3k:d, 6pc5:N, 6pc6:N, 6pc7:N, 6pc8:N, 6pch:N, 6pcq:N, 6pcr:N, 6pcs:N, 6pct:N, 8peg:c, 8phj:d, 6pj6:L, 7pjs:D, 7pjt:D, 7pju:D, 7pjv:D, 7pjw:D, 7pjx:D, 7pjy:D, 7pjz:D, 8pkl:c, 8pva:d, 7q4k:BD, 8q4f:d, 6q97:C, 6q98:C, 6q9a:C, 8qbt:D, 6qdw:d, 7qg8:Q, 7qgh:Q, 7qgn:Q, 7qgr:Q, 8qk7:C, 8qoa:d, 7qq3:L, 6qul:D, 8r6c:d, 8r8m:d, 8rpy:D, 8rpz:D, 8rq0:D, 8rq2:D, 6s0k:D, 7s1g:L, 7s1h:L, 7s1i:L, 7s1j:L, 7s1k:L, 7sa4:C, 7ss9:c, 7ssd:c, 7ssl:c, 7ssn:c, 7sso:c, 7ssw:c, 7st2:c, 7st6:c, 7st7:c, 8syl:D, 6szs:D, 8t5d:D, 8t5h:D, 6tbv:L031, 6tc3:L031, 7tos:L03, 4u1u:BD, 4u1u:DD, 4u1v:BD, 4u1v:DD, 4u20:BD, 4u20:DD, 4u24:BD, 4u24:DD, 4u25:BD, 4u25:DD, 4u26:BD, 4u26:DD, 4u27:BD, 4u27:DD, 5u4i:D, 6u48:CD, 5u9f:05, 5u9g:05, 7ug7:LC, 7uph:L, 8upo:j, 8upr:j, 8uql:j, 8uqm:j, 8uqp:j, 8ur0:j, 8urh:j, 8uri:j, 8urx:j, 8ury:j, 4uy8:D, 5uyk:05, 5uyl:05, 5uym:05, 5uyn:05, 5uyp:05, 5uyq:05, 4v4h:BD, 4v4h:DD, 4v4q:BD, 4v4q:DD, 4v4v:BB, 4v4w:BB, 4v50:BD, 4v50:DD, 4v52:BD, 4v52:DD, 4v53:BD, 4v53:DD, 4v54:BD, 4v54:DD, 4v55:BD, 4v55:DD, 4v56:BD, 4v56:DD, 4v57:BD, 4v57:DD, 4v5b:AD, 4v5b:CD, 4v5h:BD, 4v5y:BD, 4v5y:DD, 4v64:BD, 4v64:DD, 4v65:BY, 4v66:BY, 4v69:BD, 4v6c:BD, 4v6c:DD, 4v6d:BD, 4v6d:DD, 4v6e:BD, 4v6e:DD, 4v6k:AE, 4v6l:BE, 4v6m:BD, 4v6n:AE, 4v6o:BE, 4v6p:BE, 4v6q:BE, 4v6r:BE, 4v6s:AE, 4v6t:BD, 4v6v:BE, 4v6y:BD, 4v6z:BD, 4v70:BD, 4v71:BD, 4v72:BD, 4v73:BD, 4v74:BD, 4v75:BD, 4v76:BD, 4v77:BD, 4v78:BD, 4v79:BD, 4v7a:BD, 4v7b:BD, 4v7c:BE, 4v7d:AE, 4v7i:AD, 4v7s:BD, 4v7s:DD, 4v7t:BD, 4v7t:DD, 4v7u:BD, 4v7u:DD, 4v7v:BD, 4v7v:DD, 4v85:BD, 4v89:BD, 4v9c:BD, 4v9c:DD, 4v9d:CD, 4v9d:DD, 4v9o:AD, 4v9o:CD, 4v9o:ED, 4v9o:GD, 4v9p:AD, 4v9p:CD, 4v9p:ED, 4v9p:GD, 8vs9:L03, 8vsa:L03, 6vu3:j, 6vwl:B, 6vwm:B, 6vwn:B, 6vyq:j, 6vyr:j, 6vys:j, 6vyt:j, 6vyu:j, 6vyw:j, 6vyx:j, 6vyy:j, 6vyz:j, 6vz2:j, 6vz3:j, 6vz5:j, 6vz7:j, 6vzj:j, 8w51:D, 5wdt:D, 6wd0:c, 6wd1:c, 6wd2:c, 6wd3:c, 6wd4:c, 6wd5:c, 6wd6:c, 6wd7:c, 6wd8:c, 6wd9:c, 6wda:c, 6wdb:c, 6wdc:c, 6wdd:c, 6wde:c, 6wdf:c, 6wdg:c, 6wdh:c, 6wdi:c, 6wdj:c, 6wdk:c, 6wdl:c, 6wdm:c, 5we4:D, 5we6:D, 4wf1:BD, 4wf1:DD, 5wf0:D, 5wfk:D, 5wfs:D, 6wnt:c, 6wnv:c, 6wnw:c, 4woi:BD, 4woi:CD, 4www:RD, 4www:YD, 6wyv:N, 6x6t:j, 6x7f:j, 6x7k:j, 6x9q:j, 6xdq:j, 6xdr:j, 6xgf:j, 6xii:j, 6xij:j, 6xz7:D, 6xza:D2, 6xzb:D2, 6y69:D, 7y7c:d, 7y7d:d, 7y7e:d, 7y7f:d, 7y7g:d, 7y7h:d, 4ybb:CD, 4ybb:DD, 7yla:L, 6ys3:d, 6ysr:D, 6yss:D, 6yst:D, 6ysu:D, 7z20:d, 7zod:d, 7zp8:d, 7zq5:d, 7zq6:d, 6ztj:BD, 6ztl:BD, 6ztm:BD, 6ztn:BD, 6zto:BD, 6ztp:BD, 7zta:L031, 6zu1:BD
14 4fl2:A 555 27 0.0667 0.0198 0.4074 9.0 1a81:A, 1a81:C, 1a81:I, 8bi2:A, 5c26:A, 5c27:A, 1csy:A, 1csz:A, 5cxh:A, 5cxz:A, 5cy3:A, 4dfl:A, 4dfn:A, 3emg:A, 4f4p:A, 4fl1:A, 4fl3:A, 3fqe:A, 3fqh:A, 3fqh:B, 3fqs:A, 4fyn:A, 4fyo:A, 4fz6:A, 4fz7:A, 4gfg:A, 5ghv:A, 5ghv:B, 6hm6:A, 6hm7:A, 4i0r:A, 4i0s:A, 4i0t:A, 5lma:A, 5lmb:A, 5lmb:B, 4puz:A, 4puz:B, 4pv0:A, 4px6:A, 7q5t:EEE, 7q5t:CCC, 7q5t:DDD, 7q5t:AAA, 7q5t:BBB, 7q5t:FFF, 7q5u:FFF, 7q5u:DDD, 7q5u:BBB, 7q5u:CCC, 7q5u:EEE, 7q5u:AAA, 7q5w:BBB, 7q5w:DDD, 7q5w:FFF, 7q5w:EEE, 7q5w:AAA, 7q5w:CCC, 8rrq:A, 8rrz:A, 4rss:A, 4rx7:A, 4rx8:A, 4rx9:A, 3srv:A, 3srv:B, 6ssb:A, 5t68:A, 5t68:B, 5tiu:A, 5tr6:A, 5tt7:A, 3tub:A, 3tuc:A, 3tud:A, 3vf8:A, 3vf9:A, 6vov:A, 6vov:B, 4wnm:A, 8x5k:A, 1xbb:A, 1xbc:A, 4xg3:A, 4xg3:B, 4xg4:A, 4xg6:A, 4xg7:A, 4xg8:A, 4xg8:C, 4xg9:A, 4xg9:B, 5y5t:A, 5y5u:A, 5y5u:B, 4yjo:A, 4yjp:A, 4yjq:A, 4yjr:A, 4yjs:A, 4yjt:A, 4yju:A, 4yjv:A, 6zc0:A, 6zcp:A, 6zcq:A, 6zcr:A, 6zcs:A, 6zcu:A, 6zcx:A, 6zcy:A
15 8sfj:A 1001 36 0.0848 0.0140 0.3889 9.1

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218