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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
DDQVKKIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRV
QVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRF
KASGVEGADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRM
CINTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFEGRITPELLTRGKFN
TSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGS
LYKTHPQYSRRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEM
ELGLRKQTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELF
DHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVV
NDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVNEYSLN
AGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDD
SILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSED
GSGKGAALITAVGVRLRTE

The query sequence (length=899) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1qha:A 903 899 1.0000 0.9956 1.0000 0.0 1bg3:A, 1bg3:B, 1cza:N, 1dgk:N, 4f9o:A, 4f9o:B, 4foe:A, 4foe:B, 4foi:A, 4foi:B, 4fpa:A, 4fpa:B, 4fpb:A, 4fpb:B, 1hkb:A, 1hkb:B, 1hkc:A, 1qha:B
2 5hfu:B 897 896 0.7353 0.7369 0.7377 0.0 5hex:A, 5hex:B, 5hfu:A, 2nzt:A
3 5hfu:B 897 449 0.2759 0.2765 0.5523 2.28e-176 5hex:A, 5hex:B, 5hfu:A, 2nzt:A
4 2nzt:B 867 896 0.7175 0.7439 0.7199 0.0
5 2nzt:B 867 449 0.2681 0.2780 0.5367 9.69e-164
6 5hg1:A 867 896 0.7141 0.7405 0.7165 0.0
7 5hg1:A 867 449 0.2759 0.2860 0.5523 2.70e-176
8 3hm8:A 441 445 0.3159 0.6440 0.6382 0.0 3hm8:B, 3hm8:C, 3hm8:D
9 3hm8:A 441 446 0.2570 0.5238 0.5179 9.24e-162 3hm8:B, 3hm8:C, 3hm8:D
10 3idh:A 453 445 0.2692 0.5342 0.5438 3.86e-172 3a0i:X, 4dhy:A, 6e0e:A, 6e0i:A, 3f9m:A, 3fgu:A, 3fr0:A, 3goi:A, 3h1v:X, 3id8:A, 3imx:A, 4iwv:A, 4ixc:A, 4l3q:A, 4mle:A, 4mlh:A, 4no7:A, 3qic:A, 4rch:A, 3s41:A, 7t78:A, 7t78:B, 7t79:A, 7t79:B, 1v4s:A, 3vev:A, 3vey:A, 3vf6:A
11 3idh:A 453 443 0.2469 0.4901 0.5011 2.33e-158 3a0i:X, 4dhy:A, 6e0e:A, 6e0i:A, 3f9m:A, 3fgu:A, 3fr0:A, 3goi:A, 3h1v:X, 3id8:A, 3imx:A, 4iwv:A, 4ixc:A, 4l3q:A, 4mle:A, 4mlh:A, 4no7:A, 3qic:A, 4rch:A, 3s41:A, 7t78:A, 7t78:B, 7t79:A, 7t79:B, 1v4s:A, 3vev:A, 3vey:A, 3vf6:A
12 4dch:A 434 447 0.2570 0.5323 0.5168 4.64e-159 4ise:A, 4isf:A, 4isg:A, 5v4w:A, 5v4x:A
13 4dch:A 434 452 0.2336 0.4839 0.4646 2.27e-143 4ise:A, 4isf:A, 4isg:A, 5v4w:A, 5v4x:A
14 1bdg:A 444 444 0.2280 0.4617 0.4617 1.68e-121
15 1bdg:A 444 447 0.2125 0.4302 0.4273 9.08e-109
16 6jj7:A 465 455 0.1958 0.3785 0.3868 7.10e-81 6jj7:C, 6jj7:E, 6jj8:C, 6jj8:A, 6jj8:B, 6jj9:C, 6jj9:A, 6jj9:E, 5zqt:A, 5zqt:B, 5zqt:C
17 6jj7:A 465 435 0.1846 0.3570 0.3816 6.22e-77 6jj7:C, 6jj7:E, 6jj8:C, 6jj8:A, 6jj8:B, 6jj9:C, 6jj9:A, 6jj9:E, 5zqt:A, 5zqt:B, 5zqt:C
18 3o5b:A 479 468 0.1835 0.3445 0.3526 1.36e-79 3o5b:B, 3o80:A, 3o8m:A
19 3o5b:A 479 453 0.1669 0.3132 0.3311 3.77e-68 3o5b:B, 3o80:A, 3o8m:A
20 4qs7:A 455 440 0.1758 0.3473 0.3591 1.18e-72 4qs9:A
21 4qs7:A 455 436 0.1769 0.3495 0.3647 6.89e-67 4qs9:A
22 3b8a:X 470 467 0.1791 0.3426 0.3448 2.07e-70
23 3b8a:X 470 450 0.1646 0.3149 0.3289 2.79e-59
24 6pdt:A 500 480 0.1802 0.3240 0.3375 3.34e-65 6pdt:B, 6pdt:C, 6pdt:D
25 6pdt:A 500 493 0.1758 0.3160 0.3205 4.56e-56 6pdt:B, 6pdt:C, 6pdt:D
26 7zzi:B 467 474 0.1724 0.3319 0.3270 6.51e-56 7zzi:A
27 7zzi:B 467 473 0.1691 0.3255 0.3214 4.87e-47 7zzi:A
28 6ksr:A 467 473 0.1713 0.3298 0.3256 1.58e-52
29 6ksr:A 467 483 0.1769 0.3405 0.3292 1.62e-50
30 2yhx:A 457 182 0.0412 0.0810 0.2033 8.89e-05
31 2yhx:A 457 186 0.0445 0.0875 0.2151 1.22e-04
32 6n5u:A 161 50 0.0211 0.1180 0.3800 0.19 6n5u:B, 6n5u:C
33 6yny:C1 513 136 0.0423 0.0741 0.2794 1.0 6yny:A1, 6yny:B1, 6yny:C2, 6yny:A2, 6yny:B2, 6ynz:C1, 6ynz:A1, 6ynz:B1, 6ynz:C2, 6ynz:A2, 6ynz:B2, 6ynz:C4, 6ynz:A4, 6ynz:B4, 6ynz:C5, 6ynz:A5, 6ynz:B5, 6yo0:C1, 6yo0:B1, 6yo0:A1
34 4wh3:A 356 119 0.0367 0.0927 0.2773 1.5 4ock:A, 4oco:A, 4ocp:A, 4ocv:A, 4wh2:A
35 8sk1:A 162 37 0.0178 0.0988 0.4324 2.1 8sk1:B
36 2wiw:B 126 78 0.0267 0.1905 0.3077 2.5 2wiz:A, 2wj0:B, 2wj0:A
37 4fdg:B 592 59 0.0211 0.0321 0.3220 3.8 8eaf:A, 8eaf:B, 8eaf:C, 8eaf:D, 8eaf:E, 8eaf:F, 8eag:B, 8eag:C, 8eag:D, 8eag:E, 8eag:F, 8eag:A, 8eah:A, 8eah:B, 8eah:C, 8eah:D, 8eah:E, 8eah:F, 8eai:B, 8eai:C, 8eai:D, 8eai:E, 8eai:F, 8eai:A, 8eaj:A, 8eaj:B, 8eaj:C, 8eaj:D, 8eaj:E, 8eaj:F, 8eak:B, 8eak:C, 8eak:D, 8eak:E, 8eak:A, 8eak:F, 8eal:A, 8eal:B, 8eal:C, 8eal:D, 8eal:E, 8eal:F, 8eam:B, 8eam:C, 8eam:D, 8eam:E, 8eam:A, 8eam:F, 4fdg:A, 4fdg:C, 4fdg:D, 4fdg:E, 6mii:A, 6mii:B, 6mii:C, 6mii:D, 6mii:E, 6mii:F, 2vl6:A, 2vl6:B, 2vl6:C, 6wnz:B, 6wnz:A
38 4r7y:A 591 59 0.0211 0.0321 0.3220 4.5 4r7y:B, 4r7z:A, 4r7z:B, 4r7z:C, 4r7z:D, 4r7z:E, 4r7z:F, 4r7z:G, 4r7z:H, 4r7z:I, 4r7z:P, 4r7z:J, 4r7z:K, 4r7z:L, 4r7z:M, 4r7z:N, 4r7z:O
39 7wh1:A 499 105 0.0345 0.0621 0.2952 6.5
40 5dat:p0 143 111 0.0300 0.1888 0.2432 6.5 8aaf:0, 8agt:0, 8agu:0, 8agv:0, 8agw:0, 8agx:0, 8agz:0, 5apn:q, 5apo:q, 5dge:p0, 5dgf:p0, 5fcj:p0, 5i4l:p0, 6i7o:BU, 6i7o:YU, 3j77:P0, 3j78:P0, 5mei:p0, 5ndg:p0, 5obm:p0, 6r84:r, 6r86:r, 6r87:r, 6sv4:BU, 6sv4:YU, 6sv4:ZU, 6t83:ba, 5tbw:p0, 5tga:p0, 5tgm:p0, 4u3m:p0, 4u3n:p0, 4u3u:p0, 4u4n:p0, 4u4o:p0, 4u4q:p0, 4u4r:p0, 4u4u:p0, 4u4y:p0, 4u4z:p0, 4u50:p0, 4u51:p0, 4u52:p0, 4u53:p0, 4u55:p0, 4u56:p0, 4u6f:p0, 4v7r:DM, 4v8y:Bq, 4v8z:Bq
41 6hpf:A 312 50 0.0167 0.0481 0.3000 7.6
42 6sr6:C 524 187 0.0467 0.0802 0.2246 9.2 4gni:A, 4gni:B, 5mb9:B, 5mb9:A, 6sr6:A, 7z3n:D, 7z3o:D
43 3d6y:A 277 32 0.0156 0.0505 0.4375 9.7 1bow:A, 7ckq:G, 7ckq:I, 3d6z:A, 3d70:A, 3d71:A, 1exi:A, 1exj:A, 3q1m:A, 3q2y:A, 3q3d:A, 3q5p:A, 3q5r:A, 3q5s:A, 1r8e:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218