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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
DDLMLALALADRADELTRVRFGALDLRIDTKPDLTPVTDADRAVESDVRQTLGRDRPGDGVLGEEFGGSTTFTGRQWIVD
PIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRRWWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLS
GWARPGLRERFIGLTDTVWRVRAYGDFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGPHGGSAV
ATNGLLHDEVLTRLN

The query sequence (length=255) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5zon:A 256 255 1.0000 0.9961 1.0000 0.0 5yht:A, 5yht:B, 5zon:B, 5zon:C, 5zon:D
2 2p3n:A 256 251 0.3020 0.3008 0.3068 1.59e-26 2p3n:B, 2p3n:C, 2p3n:D
3 5eq9:B 260 204 0.2745 0.2692 0.3431 9.77e-26 5eq8:A, 5eq9:A, 5eq9:C, 5eq9:D, 5t3j:A
4 4as5:A 274 241 0.2824 0.2628 0.2988 3.40e-21 4as5:B, 4as5:C, 4as5:D
5 2bji:A 274 243 0.2980 0.2774 0.3128 8.89e-20 2bji:B
6 8wdq:A 273 241 0.3137 0.2930 0.3320 1.51e-19 8wdq:B
7 2czi:A 259 236 0.2902 0.2857 0.3136 6.66e-18 2czh:B
8 5dw8:A 260 225 0.2745 0.2692 0.3111 1.36e-17 5dw8:B, 5j16:A, 5j16:B, 5j16:C, 5j16:D
9 3luz:B 234 195 0.2588 0.2821 0.3385 6.15e-17
10 6giu:A 275 241 0.2706 0.2509 0.2863 6.66e-17 4as4:A, 4as4:B, 1awb:A, 1awb:B, 6giu:B, 6gj0:A, 6gj0:B, 2hhm:A, 2hhm:B, 1ima:A, 1ima:B, 1imb:A, 1imb:B, 1imc:A, 1imc:B, 1imd:A, 1imd:B, 1ime:A, 1ime:B, 6zk0:AAA, 6zk0:BBB
11 3lv0:A 258 215 0.2745 0.2713 0.3256 7.92e-17 3luz:A, 3lv0:B
12 4hxv:A 317 308 0.2980 0.2397 0.2468 2.99e-15 4o7i:A
13 6ib8:B 270 204 0.2471 0.2333 0.3088 5.05e-15 6ib7:A, 6ib8:A, 2qfl:A, 6tqn:T, 6tqn:S, 6tqo:T, 6tqo:S
14 1dk4:A 252 179 0.1804 0.1825 0.2570 4.70e-14 1dk4:B, 1g0h:A, 1g0h:B, 1g0i:A, 1g0i:B
15 5eyg:B 265 225 0.2235 0.2151 0.2533 4.04e-13 5eyg:A, 5eyh:A, 5eyh:B, 5f24:A, 5f24:B, 4g61:A, 4g61:B, 4i3e:A, 4i3e:B, 4i3y:A, 4i3y:B, 4i40:A, 4i40:B, 4ptk:A, 4ptk:B, 3ryd:A, 3ryd:C
16 1k9y:A 354 199 0.2196 0.1582 0.2814 1.85e-09 1k9z:A, 1ka0:A, 1ka1:A, 1qgx:A
17 6b5z:A 252 235 0.2549 0.2579 0.2766 1.17e-08 6b5z:B, 6b60:A, 6b60:B, 6b61:A, 6b61:B, 6b62:A, 6b62:B, 6b63:A, 6b63:B, 6b64:A, 6b64:B, 6b65:A, 6b65:B, 6b66:A, 6b66:B, 1lbx:A, 1lbx:B, 1lby:A, 1lby:B, 1lbz:A, 1lbz:B
18 2wef:A 303 264 0.2431 0.2046 0.2348 1.19e-07 1jp4:A
19 8f9y:A 352 109 0.1373 0.0994 0.3211 6.33e-07
20 5djj:A 257 64 0.1059 0.1051 0.4219 1.57e-04 5djg:A, 5djh:A, 5dji:A, 5djk:A
21 1inp:A 400 184 0.1725 0.1100 0.2391 0.32
22 5w81:A 1173 58 0.0784 0.0171 0.3448 2.4
23 1lml:A 465 27 0.0471 0.0258 0.4444 3.1
24 9ax8:z 509 44 0.0549 0.0275 0.3182 3.9 3jcj:f, 3jcn:b, 5me0:W, 5me1:W, 6o7k:f, 6o9k:z
25 1zh8:A 325 64 0.0706 0.0554 0.2812 4.2 1zh8:B
26 8onh:I 343 47 0.0549 0.0408 0.2979 6.0
27 3voc:A 416 66 0.0745 0.0457 0.2879 9.4
28 7kir:A 326 170 0.1529 0.1196 0.2294 9.8 7kio:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218