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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
DDLLTRYRANPAMMKNLKLSDIRGALLKFAKDQVGSRFIQQELASSKDRFEKDSIFDEVVSNADELVDDIFGNYVVQKFF
EYGEERHWARLVDAIIDRVPEYAFQMYACRVLQKALEKINEPLQIKILSQIRHVIHRCMKDQNGNHVVQKAIEKVSPQYV
QFIVDTLLESSNTIYEMSVDPYGCRVVQRCLEHCSPSQTKPVIGQIHKRFDEIANNQYGNYVVQHVIEHGSEEDRMVIVT
RVSNNLFEFATHKYSSNVIEKCLEQGAVYHKSMIVGAACHHQEGSVPIVVQMMKDQYANYVVQKMFDQVTSEQRRELILT
VRPHIPVLRQFPHGKHILAKLEKY

The query sequence (length=344) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7cgm:A 349 344 0.9942 0.9799 0.9942 0.0 7cgf:A, 7cgg:A, 7cgh:A, 7cgi:A, 7cgj:A, 7cgk:A, 7cgl:A, 6nod:A, 6nod:B, 6nod:C
2 3q0q:A 343 344 0.4419 0.4431 0.4419 1.26e-104 3bsb:B, 3bsx:A, 3bsx:B, 1m8w:A, 1m8w:B, 1m8x:A, 1m8x:B, 1m8y:A, 1m8y:B, 3q0l:A, 3q0l:B, 3q0m:A, 3q0m:B, 3q0n:A, 3q0n:B, 3q0o:A, 3q0o:B, 3q0p:A, 3q0p:B, 3q0r:A, 3q0s:A, 2yjy:A, 2yjy:B
3 5kla:A 337 328 0.4128 0.4214 0.4329 3.77e-99 5kl1:A, 5kl8:A
4 5kla:A 337 251 0.1686 0.1721 0.2311 5.88e-15 5kl1:A, 5kl8:A
5 5yki:A 383 382 0.4012 0.3603 0.3613 4.57e-77
6 3k49:A 353 354 0.3895 0.3796 0.3785 1.78e-75 3k49:C, 3k49:E, 3k4e:A, 3k4e:C, 3k4e:E
7 3k49:A 353 169 0.1279 0.1246 0.2604 1.09e-12 3k49:C, 3k49:E, 3k4e:A, 3k4e:C, 3k4e:E
8 3bx2:A 328 329 0.2965 0.3110 0.3100 5.15e-41 3bx2:B, 3bx3:A, 3bx3:B, 4dzs:A, 4dzs:B
9 3bx2:A 328 215 0.1512 0.1585 0.2419 1.85e-15 3bx2:B, 3bx3:A, 3bx3:B, 4dzs:A, 4dzs:B
10 5bz1:A 371 356 0.2733 0.2534 0.2640 2.88e-36 5bym:A, 5bz5:A, 5bzu:A, 5bzv:A
11 8sj7:A 404 335 0.2733 0.2327 0.2806 1.35e-32 3k5q:A, 3k5y:A, 3k5z:A, 3k61:A, 3k62:A, 3k64:A, 6noc:A, 6nof:A, 6noh:A, 6pun:A, 6pun:C, 3qg9:A, 3qgb:A, 3qgc:A, 7rzz:A, 7s02:A, 3v6y:A, 3v74:A
12 3v71:A 364 312 0.2297 0.2170 0.2532 8.73e-19
13 3v71:A 364 247 0.1657 0.1566 0.2308 2.65e-07
14 6ny5:A 386 258 0.1657 0.1477 0.2209 1.31e-06 6ny5:B
15 6ny5:A 386 92 0.0610 0.0544 0.2283 1.7 6ny5:B
16 4wzw:A 505 113 0.0872 0.0594 0.2655 0.020
17 4wzw:A 505 41 0.0378 0.0257 0.3171 0.15
18 4wzw:A 505 252 0.1453 0.0990 0.1984 0.46
19 5d6s:A 370 87 0.0610 0.0568 0.2414 1.4 5d6s:B, 5d6s:C, 5d6s:D, 5d6s:E
20 2b30:A 284 141 0.0843 0.1021 0.2057 1.7 2b30:B, 2b30:C, 2b30:D
21 5g0f:A 110 41 0.0349 0.1091 0.2927 1.9
22 5wzk:A 513 157 0.1105 0.0741 0.2420 2.7
23 3b7w:A 537 45 0.0378 0.0242 0.2889 3.9 3c5e:A, 3day:A, 3eq6:A, 3eq6:B, 3gpc:A, 3gpc:B, 2vze:A, 2vze:B, 2vze:C, 2wd9:A, 2wd9:B, 2wd9:C
24 5wzg:A 534 127 0.0843 0.0543 0.2283 5.5 5wzh:A, 5wzi:A, 5wzj:A
25 3dls:A 285 87 0.0785 0.0947 0.3103 6.5 3dls:C, 3dls:B, 3dls:D, 3dls:E, 3dls:F
26 6ks6:z 538 59 0.0465 0.0297 0.2712 6.6 6ks6:Z, 4v81:F, 4v81:N, 4v81:f, 4v81:n, 4v8r:AZ, 4v8r:Az, 4v8r:BZ, 4v8r:Bz, 4v94:F, 4v94:N, 4v94:f, 4v94:n, 7ylw:Z, 7ylw:z, 7ylx:Z, 7ylx:z, 7yly:Z, 7yly:z
27 7x6s:A 1453 62 0.0465 0.0110 0.2581 9.1 5ltf:A, 5ltn:A, 5ltn:B, 5t2t:A
28 7x6v:A 1381 62 0.0465 0.0116 0.2581 9.7

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218