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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
DDKELIEYFKSQMKEDPDMASAVAAIRTLLEFLKRDKGETIQGLRANLTSAIETLCGVDSSVAVSSGGELFLRFISDYSK
CKKIMIERGELFLRRISLSRNKIADLCHTFIKDGATILTHAYSRVVLRVLEAAVAAKKRFSVYVTESQPDLSGKKMAKAL
CHLNVPVTVVLDAAVGYIMEKADLVIVGAEGVVENGGIINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPD
KFKYKDLKEEHPWVDYTAPSLITLLFTDLGVLTPSAVSDELIKLYLG

The query sequence (length=287) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3ecs:C 294 292 0.9930 0.9694 0.9760 0.0 3ecs:B, 3ecs:D, 3ecs:E, 3ecs:F, 3ecs:G, 3ecs:H, 7kma:A, 7kma:C, 7kma:D, 7kma:E, 7kma:F, 7kma:G, 7kma:H, 7kmf:H, 7kmf:G
2 7kma:B 268 285 0.9338 1.0000 0.9404 0.0
3 3a9c:B 325 229 0.2439 0.2154 0.3057 3.76e-27 3a9c:A, 3a9c:C, 3a9c:D, 3a9c:E, 3a9c:F, 3vm6:A, 3vm6:B, 3vm6:C
4 6o85:E 357 204 0.2195 0.1765 0.3088 3.99e-26
5 5yfj:A 322 191 0.2056 0.1832 0.3089 1.47e-25 5yfj:B, 5yfj:C, 5yfs:A, 5yfs:B, 5yfs:C, 5yft:A, 5yft:B, 5yft:C, 5yfu:A, 5yfu:B, 5yfu:C, 5yfv:A, 5yfv:B, 5yfv:C, 5yfw:A, 5yfw:B, 5yfw:C, 5yfx:A, 5yg5:A, 5yg5:B, 5yg5:C, 5yg6:A, 5yg6:C, 5yg6:B, 5yg7:A, 5yg7:C, 5yg7:B, 5yg8:A, 5yg8:B, 5yg8:C, 5yg9:A, 5yg9:B, 5yg9:C, 5yga:A, 5yga:B, 5yga:C
6 6caj:C 318 270 0.2718 0.2453 0.2889 2.03e-22 6caj:D, 6ezo:C, 6ezo:D, 7l7g:C, 7l7g:D, 6o81:C, 6o81:D, 6o85:C, 6o85:D
7 6jly:G 363 227 0.2091 0.1653 0.2643 3.04e-17
8 6jly:C 338 173 0.1916 0.1627 0.3179 1.25e-16 6jly:D, 6jlz:C, 6jlz:D
9 2yvk:A 349 267 0.2334 0.1920 0.2509 5.12e-10 2yrf:A, 2yrf:B, 2yvk:B, 2yvk:C, 2yvk:D
10 4gz9:A 562 51 0.0697 0.0356 0.3922 0.33 9eou:A, 4gza:H, 2orz:A, 2qqm:A
11 7m0r:E 458 51 0.0697 0.0437 0.3922 0.34 7m0r:F
12 2z09:A 124 97 0.1080 0.2500 0.3196 1.4 2z08:A
13 3fa3:B 302 56 0.0767 0.0728 0.3929 1.7 3fa3:A, 3fa3:C, 3fa3:D, 3fa3:E, 3fa3:F, 3fa3:G, 3fa3:H, 3fa3:I, 3fa3:J, 3fa3:K, 3fa3:L, 3fa3:M, 3fa3:N, 3fa3:O, 3fa3:P, 3fa4:A, 3fa4:B, 3fa4:C, 3fa4:D, 3fa4:E, 3fa4:F, 3fa4:G, 3fa4:H, 3fa4:I, 3fa4:J, 3fa4:K, 3fa4:L
14 6pcm:A 793 36 0.0523 0.0189 0.4167 3.1 6pcm:B
15 4l1w:A 325 75 0.0697 0.0615 0.2667 3.3 6a7a:A, 3c3u:A, 3gug:A, 2hdj:A, 2hdj:B, 1ihi:A, 1ihi:B, 6ijx:A, 2ipj:A, 2ipj:B, 1j96:A, 1j96:B, 8jp2:A, 4jq1:A, 4jq1:B, 4jq2:A, 4jq2:B, 4jq3:A, 4jq3:B, 4jq4:A, 4jq4:B, 4jqa:A, 4jqa:B, 4jtq:A, 4jtq:B, 4jtr:A, 4jtr:B, 4l1w:B, 4l1x:A, 4l1x:B, 1mrq:A, 3nty:A, 1xjb:A, 1xjb:B, 4xo6:A, 4xo6:B, 4xo7:A, 4xo7:B, 4yvp:A, 4yvp:B
16 1qhg:A 622 143 0.1045 0.0482 0.2098 4.3
17 3pjr:A 646 143 0.1045 0.0464 0.2098 4.5 2pjr:A, 2pjr:B, 2pjr:F, 2pjr:G, 1qhh:A, 1qhh:D
18 8p82:A 1596 35 0.0418 0.0075 0.3429 5.4 8p82:B
19 1v9n:A 348 27 0.0418 0.0345 0.4444 8.0
20 6gh8:A 120 38 0.0488 0.1167 0.3684 8.6 6gh8:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218