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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
DDEEEENDDKILKELEDLRFRGQPGEAKDDGDELYYQERLKKWVKQRSCGSQRSSDLPEWRRPHPNIPDAKLNSQFKIPG
EIYSLLFNYQKTCVQWLYELYQQNCGGIIGDEMGLGKTIQVIAFIAALHHSGLLTGPVLIVCPATVMKQWCNEFQHWWPP
LRTVILHSMGSGMASDHILITTYVGLRIHSDKLLKVKWQYAVLDEGHKIRNPDSEISLTCKKLKTHNRIILSGTPIQNNL
TELWSLFDFIFPGKLGTLPVFQQQFVIPINIGGYANATNIQVQTGYKCAVALRDLISPYLLRRVKADVAKDLPQKKEMVL
FCKLTKYQRSKYLEFLHSSDLNQIQNGKRNVLFGIDILRKICNHPDLLDRDTKRHNPDYGDPKRSGKMQVVKQLLLLWHK
QGYKALLFTQSRQMLDILEEFISTKDPDLSHLNYLRMDGTTNIKGRQSLVDRFNNESFDVFLLTTRVGGLGVNLTGANRI
IIFDPDWNPSTDMQARERAWRIGQKREVSIYRLMVGGSIEEKIYHRQIFKQFLTNRILTDPKQKRFFKIHELHDLFSL

The query sequence (length=558) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8tvy:M 558 558 1.0000 1.0000 1.0000 0.0 5vvr:M
2 8he5:O 516 534 0.6219 0.6725 0.6498 0.0
3 8b3f:b 534 508 0.5287 0.5524 0.5807 0.0 8b3d:b, 7oo3:b, 7oob:b, 7oop:b, 7opc:b, 7opd:b
4 7zke:E 1623 506 0.3351 0.1152 0.3696 1.94e-94
5 7z8s:E 1514 483 0.3280 0.1209 0.3789 8.69e-92 7zb5:E, 7zb5:H
6 6vz4:K 616 461 0.3047 0.2760 0.3688 1.45e-90 6kw3:Y, 6kw4:Y, 6kw5:Q
7 6tda:S 783 471 0.3065 0.2184 0.3631 3.71e-89
8 6ne3:W 461 463 0.2975 0.3601 0.3585 4.19e-89 8v4y:W, 8v6v:W, 8v6v:X, 8v7l:W
9 6pwf:K 454 464 0.2939 0.3612 0.3534 1.19e-87
10 6uxw:A 778 460 0.2939 0.2108 0.3565 2.16e-86 7egp:A, 6iy2:O, 6iy3:O, 6uxv:A, 5x0x:O, 5x0y:O, 5z3l:O, 5z3o:O, 5z3u:O, 5z3v:O
11 7vdv:A 809 469 0.2885 0.1990 0.3433 3.11e-84 7vdt:A
12 1z3i:X 644 521 0.3190 0.2764 0.3417 4.71e-82
13 7tn2:W 895 492 0.3047 0.1899 0.3455 2.81e-81 9gd2:W, 9gd3:W
14 9gd1:W 849 483 0.3011 0.1979 0.3478 5.12e-81
15 8atf:G 442 474 0.2832 0.3575 0.3333 1.74e-79 8oo9:G, 8oos:G
16 6ftx:W 878 482 0.2993 0.1902 0.3465 2.90e-79 6g0l:W, 5j70:A, 5j70:B, 3mwy:W, 3ted:A
17 7x3t:V 792 465 0.2796 0.1970 0.3355 4.41e-79 6iro:L, 6jyl:K, 6k1p:K, 7x3w:K, 2y9z:A
18 7y8r:I 732 463 0.2849 0.2172 0.3434 9.89e-79
19 6g0l:M 855 476 0.2975 0.1942 0.3487 4.25e-78 7nkx:W, 5o9g:W
20 8kcc:K 508 466 0.2867 0.3150 0.3433 1.51e-77 8j90:K, 8kcb:K, 8wh5:K, 8wh8:K, 8wh9:K, 8wha:K, 8wha:L
21 7ux9:P 468 476 0.2903 0.3462 0.3403 2.21e-74
22 5hzr:A 552 454 0.2688 0.2717 0.3304 7.03e-70
23 7epu:B 748 469 0.2885 0.2152 0.3433 2.30e-69 8b0a:K, 7enn:K, 7otq:K
24 1z63:A 468 474 0.2778 0.3312 0.3270 3.24e-69 1z63:B
25 6ryr:W 708 512 0.2885 0.2274 0.3145 9.68e-69 2l75:A, 1mm2:A, 6q3m:D, 6ryu:W, 6ryu:V
26 7xyf:K 656 516 0.2814 0.2393 0.3043 2.39e-63 7xyg:K
27 7z7n:E 1306 257 0.1792 0.0766 0.3891 3.67e-46
28 6gej:M 688 306 0.1882 0.1526 0.3431 2.38e-45 6gen:M
29 6gej:M 688 156 0.1201 0.0974 0.4295 1.19e-30 6gen:M
30 8x19:I 864 306 0.1792 0.1157 0.3268 9.74e-43 8x1c:I
31 8x19:I 864 149 0.1201 0.0775 0.4497 3.22e-32 8x1c:I
32 6fml:G 731 302 0.1703 0.1300 0.3146 9.66e-41 8av6:G
33 6fml:G 731 157 0.1111 0.0848 0.3949 2.42e-29 8av6:G
34 7zi4:G 682 292 0.1631 0.1334 0.3116 2.18e-38
35 7zi4:G 682 143 0.1093 0.0894 0.4266 6.16e-31
36 8oo7:G 704 303 0.1738 0.1378 0.3201 2.91e-37 8oop:G
37 8oo7:G 704 156 0.1075 0.0852 0.3846 2.82e-29 8oop:G
38 5jxt:M 324 227 0.1541 0.2654 0.3789 2.83e-36 5jxt:N, 5jxt:O, 5jxt:J, 5jxt:K, 5jxt:I, 5jxt:H
39 6eg2:A 619 242 0.1470 0.1325 0.3388 1.31e-35 6eg3:A
40 8x15:I 792 149 0.1111 0.0783 0.4161 2.31e-27
41 8x15:I 792 191 0.1147 0.0808 0.3351 6.92e-26
42 8x15:I 792 55 0.0358 0.0253 0.3636 0.024
43 6l8n:A 810 304 0.1541 0.1062 0.2829 7.02e-22
44 6l8n:A 810 158 0.0914 0.0630 0.3228 2.36e-18
45 9c57:G 878 140 0.0896 0.0569 0.3571 7.23e-18
46 9c57:G 878 182 0.0986 0.0626 0.3022 3.57e-16
47 9c57:G 878 65 0.0430 0.0273 0.3692 0.016
48 8eu9:Q 426 143 0.0878 0.1150 0.3427 3.17e-16 8ets:Q, 8etu:Q, 8euf:Q
49 8eu9:Q 426 58 0.0358 0.0469 0.3448 0.047 8ets:Q, 8etu:Q, 8euf:Q
50 6rfl:Y 600 466 0.1774 0.1650 0.2124 1.86e-04 7aoh:Y, 8c8h:Y
51 7r76:A 1834 128 0.0627 0.0191 0.2734 4.35e-04 7r77:A
52 7r76:A 1834 70 0.0430 0.0131 0.3429 0.031 7r77:A
53 7r78:A 1880 132 0.0645 0.0191 0.2727 0.001
54 7r78:A 1880 70 0.0430 0.0128 0.3429 0.029
55 8sp4:A 859 177 0.0717 0.0466 0.2260 0.004 8spg:A
56 8sp4:A 859 50 0.0305 0.0198 0.3400 0.57 8spg:A
57 7t02:A 1752 100 0.0556 0.0177 0.3100 0.014
58 6k7l:A 992 151 0.0573 0.0323 0.2119 0.56 6k7i:A, 6k7j:A, 6k7k:A, 6k7m:A, 6k7n:A
59 2fkn:B 546 145 0.0627 0.0641 0.2414 1.8 2fkn:A, 2fkn:C, 2fkn:D
60 4twb:A 278 51 0.0323 0.0647 0.3529 4.1 4twb:B, 4twb:C, 4twb:D, 4twb:E, 4twb:F
61 6ior:A 241 39 0.0197 0.0456 0.2821 5.9 6iop:A, 6iop:B, 6ioq:A, 6ior:B, 6ior:C, 6ior:D, 6ios:A, 6iot:A, 6iot:B, 6iot:C, 6iot:D, 6iou:A, 6iou:B
62 7d9f:A 591 48 0.0269 0.0254 0.3125 6.1 7d9f:B, 7d9g:A, 7d9g:B, 7d9h:A, 7d9h:B, 7d9i:A, 7d9i:B, 7d9j:A, 7d9j:B
63 8wa1:c 1176 41 0.0251 0.0119 0.3415 7.4
64 8arp:C 445 82 0.0323 0.0404 0.2195 9.9 8arp:A, 8arp:B, 8arp:D, 8arp:E, 8arp:F

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218