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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
DALSGQIDKILADHPALEGAMAGITVRSAETGAVLYEHSGDTRMRPASSLKLLTAAAALSVLGENYSFTTEVRTDGTLKG
KKLNGNLYLKGKGDPTLLPSDFDKMAEILKHSGVKVIKGNLIGDDTWHDDMRLSPDMPWSDEYTYYGAPISALTASPNED
YDAGTVIVEVTPNQKEGEEPAVSVSPKTDYITIKNDAKTTAAGSEKDLTIEREHGTNTITIEGSVPVDANKTKEWISVWE
PAGYALDLFKQSLKKQGITVKGDIKTGEAPSSSDVLLSHRSMPLSKLFVPFMKLSNNGHAEVLVKEMGKVKKGEGSWEKG
LEVLNSTLPEFGVDSKSLVLRDGSGISHIDAVSSDQLSQLLYDIQDQSWFSAYLNSLPVAGNPDRMVGGTLRNRMKGTPA
QGKVRAKTGSLSTVSSLSGYAETKSGKKLVFSILLNGLIDEEDGKDIEDQIAVILANQ

The query sequence (length=458) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2j9p:A 458 458 1.0000 1.0000 1.0000 0.0 2j9p:B, 1w5d:A
2 4b4x:A 466 456 0.4563 0.4485 0.4583 2.77e-115 4b4x:B, 4b4x:C, 4b4x:D, 4b4z:A, 4b4z:B, 4b4z:C, 4b4z:D, 4ben:A, 4ben:B, 4ben:C, 4ben:D, 2vgj:A, 2vgj:B, 2vgj:C, 2vgj:D, 2vgk:A, 2vgk:B, 2vgk:C, 2vgk:D, 1w79:A, 1w8q:A, 1w8q:B, 1w8q:C, 1w8q:D, 1w8y:A, 1w8y:B, 1w8y:C, 1w8y:D, 2wke:A, 2wke:B, 2wke:C, 2wke:D, 2xdm:A, 2xdm:B, 2xdm:C, 2xdm:D, 2xk1:A, 2xk1:B, 2xk1:C, 2xk1:D, 2xln:A, 2xln:B, 2xln:C, 2xln:D, 2y4a:A, 2y4a:B, 2y4a:C, 2y4a:D, 2y55:A, 2y55:B, 2y55:C, 2y55:D, 2y59:A, 2y59:B, 2y59:C, 2y59:D, 3zcz:A, 3zcz:B, 3zcz:C, 3zcz:D, 3zvt:A, 3zvt:B, 3zvt:C, 3zvt:D, 3zvw:A, 3zvw:B, 3zvw:C, 3zvw:D
3 2ex8:A 456 443 0.2729 0.2741 0.2822 6.16e-40 2ex6:A, 2ex9:A, 2exa:A, 2exb:A
4 3a3f:A 453 430 0.2445 0.2472 0.2605 4.92e-36 3a3e:A, 3a3f:B, 3a3i:A, 3a3i:B
5 3a3e:B 433 423 0.2424 0.2564 0.2624 2.51e-32
6 7kcv:A 362 39 0.0306 0.0387 0.3590 0.85 6c39:A, 6dz8:A, 6dz8:B, 3hum:A, 3hum:B, 3hun:A, 3hun:B, 7kcw:A, 7kcx:A, 7kcy:A, 5tw4:A, 5tw4:B, 5tw8:A, 5tw8:B, 5tx9:A, 5tx9:B, 5txi:A, 5txi:B, 5ty2:A, 5ty2:B, 5ty7:A, 5ty7:B
7 1osn:A 325 53 0.0371 0.0523 0.3208 1.4 1osn:B, 1osn:C, 1osn:D
8 5zqa:A 248 53 0.0415 0.0766 0.3585 1.9 5zqb:A, 5zqb:B, 5zqb:C, 5zqb:D, 5zqc:A, 5zqc:B, 5zqc:C, 5zqc:D, 5zqd:A, 5zqd:B, 5zqd:C, 5zqd:D, 5zqd:E, 5zqd:F, 5zqd:G, 5zqd:H, 5zqe:A, 5zqe:B, 5zqe:C, 5zqe:D, 5zqe:E, 5zqe:F, 5zqe:G, 5zqe:H
9 5lcv:B 405 126 0.0655 0.0741 0.2381 3.5 7a3n:A, 5lbv:B
10 6jv4:A 221 76 0.0546 0.1131 0.3289 3.8 6jv4:B, 6jv4:C, 6jv4:D, 6lf4:A, 6lf4:B, 6lf4:C, 6lf4:D, 6lfd:A, 6lfd:B, 6lfd:C, 6lfd:D
11 7op8:A 1118 211 0.1157 0.0474 0.2512 4.2 7op1:A, 7op3:A, 7op5:A
12 7kb1:A 428 36 0.0306 0.0327 0.3889 4.3 7kb1:B, 7kb1:C, 7kb1:D
13 1tiq:A 173 67 0.0393 0.1040 0.2687 5.5 1tiq:B
14 4k6n:A 352 185 0.0852 0.1108 0.2108 7.0
15 4ppr:A 300 61 0.0437 0.0667 0.3279 7.3
16 6ywe:i 124 22 0.0262 0.0968 0.5455 8.3 6yws:i, 6ywv:i, 6ywx:i, 6ywy:i

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218