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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
DAIQIIDENKHFNTGILDYINKTSPADVGNNYHIISVFGSQSTGKSTLLNRLFNTNFDVMGIWLAYSPVVSTTLGHTTSK
SNILVMDVEGTDEDQDFERKAALFALSTSEVLIINIWETQVGLYQGANMGLLKTVFEVNLSLFGKSKLETHNDHKVLLLI
VIRDHVGVTPVESLAKTFTLDLQNMWSSLAKPAELEHLQFADFFDVTFHALNHKVLQPKEFGEGINRLGDRLVVSNELFK
PEYHHDVPIDGWTMYAERCWEQIETNKDLDLPTQQILVAQFKCDEIVESVFQEFLTKYQHHFKEVDAAPDFEELGALFAD
LRQDAFEDYDASASRYNKAVYEQKRKKLRWLINDKLKEVFDVHAKNLCNTLLEKFEKDLVALKGKDFAVNVKTLSTKLVE
DVNFQVSLMSLQGDLSLDEIILALTKDIDAIVAKQQVVELNSIVNKSVKKLSASLSKSIQFELGDPNEETWDNVLQQFKG
VYEKFGGDFGLGTSSTQNQQAIEKFKFKSWCQFYDVTHKLISREKLLALLQDRFDDKFRYDENGLPKLYLNEQDLEKTFA
VAKQHALQVLPILTFAKLADGSEIVPDYDIFDSKLREQFLDHCFAEIITEQEKLEVLAKFKKEVDAKYIETKRSIV

The query sequence (length=636) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5ca9:A 656 655 1.0000 0.9695 0.9710 0.0 5ca8:A, 5cb2:A
2 6k1z:A 544 182 0.0739 0.0864 0.2582 0.10
3 6z1p:Aw 342 115 0.0503 0.0936 0.2783 0.27
4 9bht:E 288 24 0.0220 0.0486 0.5833 0.88 9bht:B
5 6jfk:A 428 63 0.0299 0.0444 0.3016 0.92 6jfm:A, 6jfm:B
6 3iev:A 302 67 0.0314 0.0662 0.2985 1.2 7c1o:A, 3r9w:A, 3r9x:A
7 6upr:B 270 30 0.0236 0.0556 0.5000 1.3
8 5goe:A 384 63 0.0267 0.0443 0.2698 1.5 5gns:A, 5gnt:A
9 5gom:A 407 63 0.0267 0.0418 0.2698 1.6 5gnr:A, 5gof:A, 5gom:B, 5yew:A, 5yew:B, 5yew:C
10 5nkk:D 258 26 0.0204 0.0504 0.5000 1.7 5nkk:F
11 2qag:B 246 36 0.0252 0.0650 0.4444 3.0
12 7tjh:E 439 62 0.0252 0.0364 0.2581 4.9 7tji:E, 7tjj:E, 7tjk:E
13 5zr1:E 460 62 0.0252 0.0348 0.2581 5.8 7mca:E, 6rqc:E, 7tjf:E
14 2d4h:B 284 80 0.0346 0.0775 0.2750 5.9
15 5v8f:E 422 62 0.0252 0.0379 0.2581 6.2 6wgc:E, 6wgg:E, 6wgi:E
16 2atv:A 168 83 0.0330 0.1250 0.2530 6.4
17 2vfk:A 205 67 0.0346 0.1073 0.3284 6.7 2vfl:A
18 7ckf:A 256 95 0.0425 0.1055 0.2842 7.0 7ckf:B
19 3u24:A 546 51 0.0283 0.0330 0.3529 7.1
20 7og2:A 622 189 0.0708 0.0723 0.2381 7.2 7og2:B
21 8rpl:B 630 78 0.0330 0.0333 0.2692 7.6 8rpk:A, 8rpk:B, 8rpk:C, 8rpk:D, 8rpl:A, 8rpl:C, 8rpl:D
22 6gyf:B 366 19 0.0173 0.0301 0.5789 7.8 6gye:A, 6gye:B, 6gyf:A, 6gzo:A, 6gzo:B
23 7e5a:B 471 122 0.0550 0.0743 0.2869 8.0 7e5a:A
24 2ejt:A 371 54 0.0314 0.0539 0.3704 9.3 2eju:A, 2ytz:A, 2ytz:B
25 8r1a:A 587 87 0.0409 0.0443 0.2989 9.4 2b8w:A, 2b8w:B, 2b92:A, 2b92:B, 2bc9:A, 8cqb:A, 8cqb:B, 2d4h:A, 1f5n:A, 6loj:B, 8r1a:B, 8r1a:C, 8r1a:D, 8r1a:E, 8r1a:F

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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