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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
CHLEMYDQAKYKPQQASEIFADGASARPLVEHTVARGRLRIDATSTGRVDGDPNGAYVTTIPIRITPELLERGAQRYRIY
CAVCHGVNGNGRGQVGLLLNPRPPSFYDQRLLDMPDGEYYDVLVNGRRTMYPYGYRVQSISDRWAIVAHIRELQKNP

The query sequence (length=157) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6lod:E 157 157 1.0000 1.0000 1.0000 2.47e-116 6loe:E
2 6f0k:E 182 157 0.4395 0.3791 0.4395 1.84e-35
3 8k9e:E 164 165 0.4140 0.3963 0.3939 9.62e-30 8k9f:E, 8x2j:E
4 6btm:E 161 155 0.2420 0.2360 0.2452 2.22e-08
5 6adq:C 223 88 0.1529 0.1076 0.2727 7.28e-04 6adq:O, 6hwh:M, 6hwh:K, 8ovc:O, 8ovc:C, 8ovd:O, 8ovd:C, 7rh5:O, 7rh5:I, 7rh6:O, 7rh6:I, 7rh7:O, 7rh7:I
6 6adq:C 223 23 0.0637 0.0448 0.4348 9.8 6adq:O, 6hwh:M, 6hwh:K, 8ovc:O, 8ovc:C, 8ovd:O, 8ovd:C, 7rh5:O, 7rh5:I, 7rh6:O, 7rh6:I, 7rh7:O, 7rh7:I
7 7qhm:C 233 94 0.1592 0.1073 0.2660 0.001 7q21:C, 7q21:c, 7qhm:P, 7qho:C, 7qho:P
8 7qhm:C 233 23 0.0637 0.0429 0.4348 6.3 7q21:C, 7q21:c, 7qhm:P, 7qho:C, 7qho:P
9 6hwh:i 162 83 0.1465 0.1420 0.2771 0.002 6hwh:j
10 6hwh:i 162 23 0.0637 0.0617 0.4348 8.9 6hwh:j
11 1kv9:A 664 27 0.0701 0.0166 0.4074 0.066
12 7y5e:VL 134 66 0.1338 0.1567 0.3182 0.16 7y5e:V6, 7y5e:v6, 7y5e:vL, 7y7a:V9, 7y7a:v9, 7y7a:VE, 7y7a:vE, 7y7a:VO, 7y7a:vO, 7y7a:VZ, 7y7a:vZ, 7y7a:Vm, 7y7a:vm
13 7e1w:O 223 82 0.1274 0.0897 0.2439 0.43 7e1v:O, 7e1v:C, 7e1w:C, 7e1x:O, 7e1x:C, 8hcr:C, 8hcr:O
14 2d0w:A 168 87 0.1465 0.1369 0.2644 0.50 2d0w:B
15 6z1p:BL 181 57 0.0955 0.0829 0.2632 0.55
16 8snh:G 304 83 0.1847 0.0954 0.3494 0.57
17 8snh:G 304 22 0.0446 0.0230 0.3182 5.2
18 6h5l:B 220 44 0.1146 0.0818 0.4091 0.61
19 6h5l:B 220 44 0.0892 0.0636 0.3182 2.1
20 5djq:C 303 25 0.0573 0.0297 0.3600 0.97 5djq:M, 5djq:F, 5djq:I, 3mk7:C, 3mk7:M, 3mk7:F, 3mk7:I
21 5djq:C 303 64 0.1274 0.0660 0.3125 2.1 5djq:M, 5djq:F, 5djq:I, 3mk7:C, 3mk7:M, 3mk7:F, 3mk7:I
22 6xkw:p 254 54 0.1146 0.0709 0.3333 0.99 6xkx:p, 6xkz:p
23 5lo9:A 471 20 0.0701 0.0234 0.5500 1.0 5lo9:B
24 6ip5:2z 150 35 0.0828 0.0867 0.3714 1.1 7a01:G5, 7a09:k, 5a2q:S, 5aj0:BS, 9bdl:AS18, 9bdn:AS18, 9bdp:AS18, 8bhf:T3, 9bkd:f, 9bln:f, 8btk:Ar, 7cpu:SS, 7cpv:SS, 4d5l:S, 4d61:S, 6d90:TT, 6d9j:TT, 9f1b:Ar, 9f1c:Ar, 9f1d:Ar, 6fec:L, 5flx:S, 6g18:S, 6g4s:S, 6g4w:S, 6g51:S, 6g53:S, 6g5h:S, 6g5i:S, 8g5y:SS, 8g5z:SS, 8g60:SS, 8g61:SS, 8g6j:SS, 8glp:SS, 6gz3:BS, 6gz4:BS, 6gz5:BS, 6hcf:T1, 6hcj:T2, 6hcm:T1, 6hcq:T2, 8ifd:2z, 8ife:2z, 6ip6:2z, 6ip8:2z, 3j7p:SS, 3j7r:SS, 3jag:SS, 3jah:SS, 3jai:SS, 3jaj:SS, 3jan:SS, 8jdj:AE, 8jdk:AE, 8jdl:AE, 8jdm:AE, 7jqb:T, 7jqc:T, 5k0y:L, 8k2c:SS, 7k5i:S, 4kzx:S, 4kzy:S, 4kzz:S, 5lks:SS, 7ls1:A3, 7ls2:A3, 5lzs:SS, 5lzt:SS, 5lzu:SS, 5lzv:SS, 5lzw:SS, 5lzx:SS, 5lzy:SS, 5lzz:SS, 7mdz:SS, 6mtb:SS, 6mtc:SS, 6mtd:SS, 6mte:SS, 7nwg:T2, 7nwh:SS, 7nwi:SS, 7o7y:Ar, 7o7z:Ar, 7o80:Ar, 7o81:Ar, 5oa3:S, 6ole:SS, 6olf:SS, 6olg:BS, 6oli:SS, 6olz:BS, 6om0:SS, 6om7:SS, 7oya:S2, 7oyb:S2, 7oyc:S2, 7oyd:SS, 8oz0:n, 8p03:U, 8p09:U, 8p2k:Ar, 6p4g:T, 6p4h:T, 6p5i:T, 6p5j:T, 6p5k:T, 6p5n:T, 8pj1:f, 8pj2:f, 8pj3:f, 8pj4:f, 8pj5:f, 8pj6:f, 8ppk:S, 8ppl:AS, 8q7z:Ar, 8q87:Ar, 7qgg:SS, 8qoi:SS, 7qp6:f, 7qp7:f, 7qvp:SS, 7qvp:RS, 6qzp:SS, 7r4x:S, 6r5q:II, 6r6g:II, 6r6p:II, 6r7q:II, 8scb:SS, 6sgc:T1, 7syg:T, 7syh:T, 7syi:T, 7syj:T, 7syk:T, 7syl:T, 7sym:T, 7syn:T, 7syo:T, 7syp:T, 7syq:T, 7syr:T, 7sys:T, 7syt:T, 7syu:T, 7syv:T, 7syw:T, 7syx:T, 5t2c:A0, 8t4s:S, 7toq:AS18, 7tor:AS18, 7tql:T, 7ucj:SS, 7uck:SS, 4ug0:SS, 4ujc:CS, 4ujd:CS, 4uje:BS, 4v5z:Am, 4v6x:AS, 5vyc:S1, 5vyc:S6, 5vyc:S2, 5vyc:S5, 5vyc:S3, 5vyc:S4, 6w2s:T, 6w2t:T, 7wtt:S, 7wtu:S, 7wtv:S, 7wtw:S, 7wtx:S, 7wtz:S, 7wu0:S, 6xa1:SS, 7xnx:SS, 7xny:SS, 8xsx:SS, 8xsy:SS, 8xsz:SS, 8xxl:SS, 8xxm:SS, 8xxn:SS, 6y0g:SS, 8y0w:SS, 8y0x:SS, 6y2l:SS, 6y57:SS, 6yal:U, 6yam:U, 6yan:U, 6ybs:f, 8yoo:SS, 8yop:SS, 6z6l:SS, 6z6m:SS, 6z6n:SS, 7zjw:Sd, 7zjx:Sd, 6zlw:T, 6zm7:SS, 6zme:SS, 6zmi:SS, 6zmo:SS, 6zmt:T, 6zmw:f, 6zn5:T, 6zoj:S, 6zol:S, 6zon:k, 6zp4:k, 6zuo:S, 6zv6:S, 6zvh:S, 6zvj:k, 6zvk:G5, 6zxd:S, 6zxe:S, 6zxf:S, 6zxg:S, 6zxh:S
25 4yuu:V1 129 38 0.0828 0.1008 0.3421 1.3 4yuu:v1, 4yuu:V2, 4yuu:v2
26 3cc2:Q 95 57 0.1274 0.2105 0.3509 1.3 3cc4:Q, 3cc7:Q, 3cce:Q, 3ccj:Q, 3ccl:Q, 3ccm:Q, 3ccq:Q, 3ccr:Q, 3ccs:Q, 3ccu:Q, 3ccv:Q, 3cd6:Q, 3cma:Q, 3cme:Q, 3cpw:P, 3cxc:P, 1ffk:N, 3g4s:Q, 3g6e:Q, 3g71:Q, 3i55:Q, 3i56:Q, 1jj2:P, 1k73:R, 1k8a:R, 1k9m:R, 1kc8:R, 1kd1:R, 1kqs:P, 1m1k:R, 1m90:R, 1n8r:R, 1nji:R, 2otj:Q, 2otl:Q, 3ow2:P, 1q7y:R, 1q81:R, 1q82:R, 1q86:R, 2qa4:Q, 2qex:Q, 1qvf:P, 1qvg:P, 1s72:Q, 4v9f:Q, 1vq4:Q, 1vq5:Q, 1vq6:Q, 1vq7:Q, 1vq8:Q, 1vq9:Q, 1vqk:Q, 1vql:Q, 1vqm:Q, 1vqn:Q, 1vqo:Q, 1vqp:Q, 1w2b:P, 1yhq:Q, 1yi2:Q, 1yij:Q, 1yit:Q, 1yj9:Q, 1yjn:Q, 1yjw:Q
27 6ncr:A 342 62 0.1274 0.0585 0.3226 1.5 6ncr:B
28 3w5m:A 1030 30 0.0764 0.0117 0.4000 1.6 3w5n:A
29 5mxy:A 83 18 0.0573 0.1084 0.5000 1.8 5mxz:A
30 1n1z:A 537 26 0.0701 0.0205 0.4231 2.0 1n1b:A, 1n1b:B, 1n1z:B, 1n20:A, 1n20:B, 1n21:A, 1n22:A, 1n22:B, 1n23:A, 1n23:B, 1n24:A, 1n24:B
31 8yts:A 83 24 0.0573 0.1084 0.3750 2.3 8yts:B
32 6jlu:V 137 69 0.1401 0.1606 0.3188 2.3 8iwh:V, 8iwh:v, 6j3y:V, 6j3y:v, 6j3z:V, 6j3z:v, 6j40:V, 6j40:v, 8j5k:V, 8j5k:v, 6jlu:v, 7vd5:V, 7vd5:v
33 7o38:A 81 63 0.1019 0.1975 0.2540 2.8
34 6esq:A 392 23 0.0637 0.0255 0.4348 3.2 6esq:B, 6esq:C, 6esq:D
35 9c0i:A 425 30 0.0828 0.0306 0.4333 3.6 9c0j:A
36 8iug:C 316 151 0.2611 0.1297 0.2715 3.8 8hju:C, 8hjv:C, 8iun:C, 8j5o:C, 8j5p:C, 5yq7:C
37 8uf3:A 187 33 0.0764 0.0642 0.3636 3.9 8uf3:B
38 8q1b:D 245 19 0.0637 0.0408 0.5263 3.9 8q1b:O
39 8eqm:V 131 23 0.0510 0.0611 0.3478 4.1 8eqm:v
40 1p91:A 268 74 0.1338 0.0784 0.2838 4.3 1p91:B
41 1yiq:A 684 19 0.0573 0.0132 0.4737 4.4
42 2fyn:B 256 19 0.0637 0.0391 0.5263 4.8 8asi:C, 8asi:G, 8asj:C, 8asj:G, 2fyn:E, 2fyn:H, 2fyn:K, 2fyn:N, 2fyn:Q, 5kkz:B, 5kkz:F, 5kkz:L, 5kkz:P, 5kli:B, 5kli:F, 5kli:L, 5kli:P, 6nhh:B, 6nhh:F, 6nin:B, 6nin:F, 6nin:L, 6nin:P, 6nin:T, 6nin:X, 2qjk:B, 2qjk:E, 2qjk:H, 2qjk:K, 2qjk:N, 2qjk:Q, 2qjp:B, 2qjp:E, 2qjp:H, 2qjp:K, 2qjy:B, 2qjy:E, 2qjy:H, 2qjy:K, 2qjy:N, 2qjy:Q, 7tce:B, 7tce:F, 7tce:L, 7tce:P, 7tlj:F, 7tlj:B
43 5yug:E 102 38 0.0828 0.1275 0.3421 5.4 5yug:A, 5yug:B, 5yug:G, 5yuh:A
44 4jj0:A 181 43 0.0892 0.0773 0.3256 5.4 4jj0:B, 4jj3:A, 4jj3:B
45 2yev:B 319 17 0.0637 0.0313 0.5882 5.4 2yev:E
46 8xr6:V 137 63 0.1210 0.1387 0.3016 5.9 8wb4:V, 8wb4:v, 8xr6:v
47 3rwk:X 493 38 0.0764 0.0243 0.3158 6.1 3sc7:X
48 8smr:G 312 37 0.0764 0.0385 0.3243 6.2
49 6onq:A 159 56 0.1083 0.1069 0.3036 7.3
50 6rxu:UT 2033 73 0.1274 0.0098 0.2740 8.1 6rxv:UT, 6rxx:UT, 6rxz:UT
51 3vrd:A 174 44 0.0701 0.0632 0.2500 8.4
52 2yiu:B 206 18 0.0573 0.0437 0.5000 8.5 2yiu:E
53 8x38:A 430 54 0.0764 0.0279 0.2222 9.3

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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