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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AYKYLEELQRKKQSDVLRFLQRVRVWEYRQKNVIHRAARPTRPDKARRLGYKAKQGFVIYRVRVRRGNRKRPVPKGATYG
KPTNQGVNELKYQRSLRATAEERVGRRAANLRVLNSYWVNQDSTYKYFEVILVDPQHKAIRRDARYNWICDPVHKHREAR
GLTATGKKSRGINKGHKFNNTKAGRRK

The query sequence (length=187) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8aaf:A 203 187 1.0000 0.9212 1.0000 1.55e-136 8agt:A, 8agu:A, 8agv:A, 8agw:A, 8agx:A, 8agz:A, 5apn:N, 5apo:N, 7azy:R, 7b7d:LP, 8bip:LN, 8bjq:LN, 8bn3:M5, 8bqd:AQ, 8bqx:AQ, 7btb:N, 8ccs:QQ, 8cdl:QQ, 8cdr:QQ, 8ceh:QQ, 8cf5:QQ, 8cg8:QQ, 8cgn:QQ, 8civ:QQ, 8cku:QQ, 8cmj:QQ, 5dat:M5, 5dat:m5, 5dc3:M5, 5dc3:m5, 5dge:M5, 5dge:m5, 5dgf:M5, 5dgf:m5, 5dgv:M5, 5dgv:m5, 6elz:N, 6em5:N, 8eub:AN, 8evp:AN, 8evq:AN, 8evr:AN, 8evs:AN, 8evt:AN, 8ewb:AN, 8ewc:AN, 5fci:M5, 5fci:m5, 5fcj:M5, 5fcj:m5, 6ft6:N, 5gak:P, 6gq1:N, 6gqb:N, 6gqv:N, 5h4p:N, 6hd7:P, 8hfr:No, 6hhq:v, 6hhq:CP, 5i4l:M5, 5i4l:m5, 6i7o:AQ, 6i7o:XQ, 5it7:NN, 3j6x:55, 3j6y:55, 3j77:65, 3j78:65, 3jct:N, 5jcs:N, 5juo:S, 5jup:S, 5jus:S, 5jut:S, 5juu:S, 8k2d:LN, 8k82:LN, 5lyb:M5, 5lyb:m5, 5m1j:N5, 6m62:N, 5mc6:AQ, 5mei:v, 5mei:CP, 7mpi:AN, 7mpj:AN, 6n8j:N, 6n8k:N, 6n8l:N, 6n8m:a, 6n8n:a, 6n8o:a, 7n8b:AN, 7nac:N, 5ndg:M5, 5ndg:m5, 5ndv:M5, 5ndv:m5, 5ndw:M5, 5ndw:m5, 7nrc:LP, 7nrd:LP, 5obm:M5, 5obm:m5, 7of1:N, 7oh3:N, 7ohq:N, 7ohv:N, 6oig:N, 5on6:v, 5on6:CP, 7osa:eL15, 7osm:eL15, 8p8m:JV, 8p8n:JV, 8p8u:JV, 8pfr:JV, 6q8y:AQ, 6qik:O, 6qt0:O, 6qtz:O, 7r7a:N, 6r84:p, 6r86:p, 6r87:p, 6ri5:O, 7rr5:LN, 6rzz:O, 6s05:O, 6s47:AP, 6snt:t, 6sv4:AQ, 6sv4:XQ, 6sv4:zQ, 6t4q:LN, 5t62:a, 5t6r:a, 6t7i:LN, 6t7t:LN, 6t83:Ny, 6t83:Pa, 5tbw:v, 5tbw:CP, 6tb3:AQ, 5tga:M5, 5tga:m5, 5tgm:M5, 5tgm:m5, 6tnu:AQ, 7too:AL15, 7top:AL15, 7u0h:N, 4u3m:M5, 4u3m:m5, 4u3n:M5, 4u3n:m5, 4u3u:M5, 4u3u:m5, 4u4n:M5, 4u4n:m5, 4u4o:M5, 4u4o:m5, 4u4q:M5, 4u4q:m5, 4u4r:M5, 4u4r:m5, 4u4u:M5, 4u4u:m5, 4u4y:M5, 4u4y:m5, 4u4z:M5, 4u4z:m5, 4u50:M5, 4u50:m5, 4u51:M5, 4u51:m5, 4u52:M5, 4u52:m5, 4u53:M5, 4u53:m5, 4u55:M5, 4u55:m5, 4u56:M5, 4u56:m5, 4u6f:M5, 4u6f:m5, 7ug6:N, 7uoo:N, 7uqb:N, 7uqz:N, 6uz7:AN, 7v08:N, 4v4b:BL, 4v6i:BP, 4v7f:O, 4v7h:BL, 4v7r:BO, 4v7r:DO, 4v88:BN, 4v88:DN, 4v8t:N, 4v8y:BN, 4v8z:BN, 8v87:N, 4v91:N, 6woo:N, 6xiq:N, 6xir:N, 8y0u:LN, 6ylg:N, 6ylh:N, 6yly:N, 7z34:N, 6z6j:LN, 6z6k:LN, 7zpq:BM, 7zrs:BM, 7zs5:BO, 7zuw:BM, 7zux:EM, 7zw0:LQ
2 8c3a:v 203 186 0.8984 0.8276 0.9032 3.77e-124 8c3a:BI, 8cq7:v, 8cq7:BI, 8cqw:v, 8cqw:BI, 8cre:v, 8cre:BI, 8oeq:v, 8oeq:BI, 7pzy:v, 7q08:v, 7q0f:v, 7q0p:v, 7q0r:v, 8q5i:v
3 7bt6:N 183 187 0.8930 0.9126 0.8930 1.16e-115 6c0f:N, 6cb1:N, 8e5t:N, 6em1:N, 6em3:N, 6em4:N, 7ohp:N, 7ohr:N, 7ohs:N, 7ohu:N, 7ohw:N, 7ohx:N, 7ohy:N, 7r6q:N, 8v83:N, 8v84:N, 6ylx:N, 5z3g:R
4 7olc:LN 202 187 0.8663 0.8020 0.8663 1.18e-111 8i9p:LN, 8i9r:LN, 8i9t:LN, 8i9v:LN, 8i9w:LN, 8i9x:LN, 8i9y:LN, 8i9z:LN, 8ia0:LN, 7old:LN, 8oo0:LN, 8pv1:LN, 8pv2:LN, 8pv3:LN, 8pv4:LN, 8pv5:LN, 8pv6:LN, 8pv7:LN, 8pv8:LN, 8pvk:LN, 8pvl:LN, 7r81:P1, 7z3n:LN, 7z3o:LN
5 8eug:N 200 181 0.7861 0.7350 0.8122 5.51e-108 8eui:N
6 4d5y:N 204 187 0.7166 0.6569 0.7166 4.97e-99 7a01:12, 8a3d:l, 5aj0:AN, 8b5l:N, 8b6c:N, 9bdl:AL15, 9bdn:AL15, 9bdp:AL15, 7bhp:LN, 8bhf:A1, 8bpo:M2, 8btk:BN, 7cpu:LN, 7cpv:LN, 4d67:N, 6d90:N, 6d9j:N, 9f1b:BN, 9f1c:BN, 9f1d:BN, 7f5s:LN, 8fl2:L9, 8fl3:L9, 8fl4:L9, 8fl6:L9, 8fl7:L9, 8fl9:L9, 8fla:L9, 8flb:L9, 8flc:L9, 8fld:L9, 8fle:L9, 8flf:L9, 6frk:N, 6ftg:N, 6fti:N, 6ftj:N, 8g5y:LN, 8g5z:LN, 8g60:LN, 8g61:LN, 8g6j:LN, 8glp:LN, 6gz3:AN, 6gz4:AN, 6gz5:AN, 6hcf:N3, 6hcj:N3, 6hcm:N3, 6hcq:N3, 8idt:U, 8idy:U, 8ie3:U, 8ifd:2H, 8ife:2H, 8ine:U, 8inf:U, 8ink:U, 6ip5:2H, 6ip6:2H, 6ip8:2H, 8ipd:U, 8ipx:U, 8ipy:U, 8ir3:U, 3j7o:N, 3j7p:N, 3j7q:N, 3j7r:N, 3j92:N, 3jag:N, 3jah:N, 3jai:N, 3jaj:N, 3jan:N, 8jdj:S, 8jdk:S, 8jdl:S, 8jdm:S, 8k2c:LN, 5lks:LN, 6lqm:U, 6lsr:U, 6lss:U, 7ls1:H1, 7ls2:H1, 6lu8:U, 5lzs:N, 5lzt:N, 5lzu:N, 5lzv:N, 5lzw:N, 5lzx:N, 5lzy:N, 5lzz:N, 7mdz:N, 6mtb:N, 6mtc:N, 6mtd:N, 6mte:N, 7nfx:N, 7nwg:N3, 7nwh:N, 7nwi:N, 7o7y:BN, 7o7z:BN, 7o80:BN, 7o81:BN, 7obr:N, 8ohd:LN, 8oj0:LN, 8oj5:LN, 8oj8:LN, 6ole:O, 6olf:O, 6olg:AN, 6oli:O, 6olz:AN, 6om0:O, 6om7:O, 7ow7:t, 7oya:N1, 7oyb:N1, 7oyc:N1, 7oyd:N, 8p2k:BN, 6p5i:AN, 6p5j:AN, 6p5k:AN, 6p5n:AN, 8q7z:BN, 8q87:BN, 8qfd:N, 7qgg:O, 8qoi:LN, 7qvp:MN, 7qvp:LN, 7qwq:N, 7qwr:N, 7qws:N, 6qzp:LN, 6r5q:N, 6r6g:N, 6r6p:N, 6r7q:N, 8rjb:N, 8rjc:N, 8rjd:N, 8scb:N, 6sgc:N2, 6swa:M, 5t2c:t, 6t59:N3, 7tm3:N, 7toq:AL15, 7tor:AL15, 7tut:N, 7ucj:N, 7uck:N, 4ug0:LN, 4ujc:BN, 4ujd:AN, 4uje:CN, 4v5z:Bm, 4v6x:CN, 6w6l:O, 6xa1:LN, 7xnx:LN, 7xny:LN, 8xsx:LN, 8xsy:LN, 8xsz:LN, 6y0g:LN, 8y0w:LN, 8y0x:LN, 6y2l:LN, 6y57:LN, 6y6x:LN, 8yoo:LN, 8yop:LN, 6z6l:LN, 6z6m:LN, 6z6n:LN, 7zjw:LQ, 7zjx:LQ, 6zm7:LN, 6zme:LN, 6zmi:LN, 6zmo:LN, 6zvk:12
7 4v6w:CN 203 187 0.6845 0.6305 0.6845 3.70e-95 6xu6:CN, 6xu7:CN, 6xu8:CN
8 8azw:F 203 187 0.7059 0.6502 0.7059 3.90e-94 8b2l:F3, 7qiw:P, 7qiz:P
9 8ip8:HA 203 187 0.6738 0.6207 0.6738 2.91e-91 8ipa:HA, 8ipb:HA, 8jiv:CN, 4v3p:LP, 4v7e:CN
10 8esq:N 166 189 0.6845 0.7711 0.6772 4.67e-84 8esr:N, 8etc:N, 8etg:N, 8eth:N, 8eti:N, 8etj:N, 8eup:N, 8euy:N, 8ev3:N
11 5xxb:M 202 172 0.6471 0.5990 0.7035 1.60e-83
12 3j79:P 204 178 0.6150 0.5637 0.6461 1.17e-80 3jbn:AP, 3jbo:AP, 3jbp:AP, 8tpu:AP, 5umd:P
13 8fkp:L9 183 187 0.6257 0.6393 0.6257 2.03e-80 8fkq:L9, 8fkr:L9, 8fks:L9, 8fkt:L9, 8fku:L9, 8fkv:L9, 8fkw:L9, 8fkx:L9, 8fky:L9, 8fkz:L9, 8ir1:U
14 4v8p:BL 203 187 0.6364 0.5862 0.6364 2.60e-78 4v8p:CL, 4v8p:EL, 4v8p:GL
15 9bh5:CN 203 184 0.6578 0.6059 0.6685 2.67e-77 9cai:CN
16 6zu5:LN0 203 187 0.5722 0.5271 0.5722 2.22e-75
17 8a3w:M 203 178 0.5936 0.5468 0.6236 3.31e-70 8a98:M, 6az3:M, 3jcs:M, 8ovj:M, 8rxh:LM, 8rxx:LM, 5t2a:O, 5t5h:Q
18 5xy3:N 202 179 0.5401 0.5000 0.5642 4.64e-70
19 8p5d:LN0 203 185 0.5561 0.5123 0.5622 5.01e-70 8p60:LN0, 8p60:KN0, 7qca:LN0
20 6zj3:Lb 203 178 0.5989 0.5517 0.6292 3.86e-69
21 7qep:M5 203 184 0.5294 0.4877 0.5380 1.77e-67
22 7pwg:N 204 176 0.6043 0.5539 0.6420 4.52e-66 8br8:LO, 8brm:LO, 8bsi:LO, 8bsj:LO, 8btd:LO, 8btr:LO, 8fru:N, 7pwo:N2
23 8ova:BQ 203 178 0.5829 0.5369 0.6124 6.78e-66 8ove:BQ, 4v8m:BQ
24 6rm3:LN0 203 184 0.5348 0.4926 0.5435 1.25e-65
25 4v4n:AM 194 175 0.4545 0.4381 0.4857 4.22e-48 6skf:BP, 6skg:BP, 6th6:BP, 4v6u:BM
26 7r6k:N 92 166 0.4920 1.0000 0.5542 1.10e-42
27 4v9f:M 195 173 0.3904 0.3744 0.4220 4.32e-37 3cc2:M, 3cc4:M, 3cc7:M, 3cce:M, 3ccj:M, 3ccl:M, 3ccm:M, 3ccq:M, 3ccr:M, 3ccs:M, 3ccu:M, 3ccv:M, 3cd6:M, 3cma:M, 3cme:M, 3cpw:L, 3g4s:M, 3g6e:M, 3g71:M, 3i55:M, 3i56:M, 2otj:M, 2otl:M, 2qa4:M, 2qex:M, 1s72:M, 1vq4:M, 1vq5:M, 1vq6:M, 1vq7:M, 1vq8:M, 1vq9:M, 1vqk:M, 1vql:M, 1vqm:M, 1vqn:M, 1vqo:M, 1vqp:M, 1yhq:M, 1yi2:M, 1yij:M, 1yit:M, 1yj9:M, 1yjn:M, 1yjw:M
28 3cxc:L 194 173 0.3743 0.3608 0.4046 3.35e-36 1jj2:L, 1k73:N, 1k8a:N, 1k9m:N, 1kc8:N, 1kd1:N, 1kqs:L, 1m1k:N, 1m90:N, 1n8r:N, 1nji:N, 3ow2:L, 1q7y:N, 1q81:N, 1q82:N, 1q86:N, 1qvf:L, 1qvg:L, 1w2b:L
29 8hku:L15E 169 171 0.4225 0.4675 0.4620 3.10e-35 8hkv:L15E, 8hky:L15E, 8hkz:L15E, 8hl1:L15E, 8hl2:L15E, 8hl3:L15E, 8hl4:L15E, 8hl5:L15E
30 1ffk:I 194 171 0.3743 0.3608 0.4094 4.78e-25
31 8ee7:A 456 55 0.0963 0.0395 0.3273 0.63 8ee4:A, 8ee4:B, 8ee4:C, 8ee4:D, 8ee4:E, 8ee4:F, 8ee7:B, 8eea:A, 8eea:B, 8eea:C, 8eea:D, 8eea:E, 8eea:F, 8sux:A, 8sux:B, 8sux:C, 8sux:D, 8sux:E, 8sux:F
32 6zj3:Lr 218 67 0.1123 0.0963 0.3134 1.5
33 5ve5:A 350 43 0.0695 0.0371 0.3023 2.1 5ve3:B, 5ve3:A, 5ve4:A, 5ve4:B, 5ve4:C, 5ve5:B, 5ve5:C
34 5tky:A 597 89 0.1337 0.0419 0.2809 3.8 5tky:B
35 5x5h:A 385 113 0.1176 0.0571 0.1947 3.9
36 1o12:A 363 33 0.0695 0.0358 0.3939 3.9 1o12:B
37 8j6g:A 621 72 0.0963 0.0290 0.2500 5.0 3amo:A, 3amo:B, 1av4:A, 1avl:A, 2bt3:A, 2cfd:A, 2cfd:B, 2cfg:A, 2cfg:B, 2cfk:A, 2cfl:A, 2cfw:A, 2cg0:A, 2cg1:A, 2cwt:A, 2cwt:B, 2cwu:A, 2cwu:B, 2cwv:A, 2cwv:B, 2d1w:A, 2d1w:B, 2e2t:A, 2e2u:A, 2e2u:B, 2e2v:A, 2e2v:B, 7f8k:A, 1iqx:A, 1iqx:B, 1iu7:A, 1iu7:B, 1ivu:A, 1ivu:B, 1ivv:A, 1ivv:B, 1ivw:A, 1ivw:B, 1ivx:A, 1ivx:B, 3kii:A, 3kii:B, 3kn4:A, 6l9c:X, 1rjo:A, 1sih:A, 1sii:A, 1ui7:A, 1ui7:B, 1ui8:A, 1ui8:B, 1w4n:A, 1w4n:B, 1w5z:A, 1w6c:A, 1w6g:A, 3wa2:X, 3wa3:A, 3wa3:B, 7wir:A, 7wir:B, 7wis:A, 7wis:B, 1wmn:A, 1wmn:B, 1wmp:A, 1wmp:B, 7wno:X, 7wnp:X, 3x3x:A, 3x3x:B, 3x3y:A, 3x3y:B, 3x3z:A, 3x3z:B, 3x40:A, 3x40:B, 3x41:A, 3x41:B, 3x42:A, 3x42:B, 7ynh:A, 7ynh:B, 2yx9:A, 2yx9:B, 2zl8:A, 2zl8:B, 5zou:A, 5zou:B, 5zow:A, 5zow:B, 5zox:A, 5zox:B, 5zoy:A, 5zoy:B, 5zoz:A, 5zoz:B, 5zp0:A, 5zp0:B, 5zp1:A, 5zp1:B, 5zp2:A, 5zp2:B, 5zp3:A, 5zp3:B, 5zp4:A, 5zp4:B, 5zp5:A, 5zp5:B, 5zp6:A, 5zp6:B, 5zp7:A, 5zp7:B, 5zp8:A, 5zp8:B, 5zp9:A, 5zp9:B, 5zpa:A, 5zpa:B, 5zpb:A, 5zpb:B, 5zpc:A, 5zpc:B, 5zpd:A, 5zpd:B, 5zpe:A, 5zpe:B, 5zpf:A, 5zpf:B, 5zpg:A, 5zpg:B, 5zph:A, 5zph:B, 5zpi:A, 5zpi:B, 5zpj:A, 5zpj:B, 5zpk:A, 5zpk:B, 5zpl:A, 5zpl:B, 5zpm:A, 5zpm:B, 5zpn:A, 5zpn:B, 5zpo:A, 5zpo:B, 5zpp:A, 5zpp:B, 5zpq:A, 5zpq:B, 5zpr:A, 5zpr:B, 5zps:A, 5zps:B, 5zpt:A, 5zpt:B
38 3acs:A 822 36 0.0856 0.0195 0.4444 6.1 3acs:B, 3act:A, 3act:B, 3afj:A, 3afj:B, 2cqs:A, 2cqs:B, 2cqt:A, 2cqt:B, 3qfy:A, 3qfy:B, 3qfz:A, 3qfz:B, 3qg0:A, 3qg0:B
39 7oro:A 2008 20 0.0588 0.0055 0.5500 7.0 7ori:A
40 6z6b:PPP 2036 20 0.0588 0.0054 0.5500 7.6 6z6b:EEE
41 7orj:A 2129 20 0.0588 0.0052 0.5500 7.6
42 7orl:A 2183 20 0.0588 0.0050 0.5500 7.7 7oa4:AAA, 7oa4:BBB, 7oa4:DDD, 7oa4:GGG, 7ork:A, 7plr:AAA, 7plr:BBB, 7plr:DDD, 7plr:GGG, 2xi5:A, 2xi5:B, 2xi5:C, 2xi5:D, 2xi7:A, 2xi7:B, 2xi7:C, 2xi7:D
43 7vqo:A 1180 79 0.1016 0.0161 0.2405 7.9 7vqo:B, 7vqo:C, 7vqo:D
44 7orm:A 2145 20 0.0588 0.0051 0.5500 8.0
45 6z6g:A 2142 20 0.0588 0.0051 0.5500 8.1 5amr:A
46 6z8k:A 2158 20 0.0588 0.0051 0.5500 8.1 5amq:A, 7orn:A
47 7c0k:B 397 67 0.1230 0.0579 0.3433 8.7 7c0f:A, 7c0f:B, 7c0k:A, 7c0l:A, 7c0l:B, 7c0o:A, 7c0o:B, 7c0r:A, 7c0r:B, 7c0s:A, 7c0s:B, 7c0t:A, 7c0t:B, 7c0u:A, 7c0u:B, 7c0v:A, 7c0v:B, 7c0w:A, 7c0w:B, 7c0x:A, 7c0x:B, 7c0y:A, 7c0y:B, 7c0z:A, 7c0z:B, 7c14:A, 7c14:B, 7c15:A, 7c15:B, 7c16:A, 7c16:B, 7c19:A, 7c19:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218