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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AYATQGFNLDDRGRRIVVDPVTRIEGHMRCEVNVDANNVIRNAVSTGTMWRGLEVILKGRDPRDAWAFVERICGVCTGCH
ALASVRAVENALDIRIPKNAHLIREIMAKTLQVHDHAVHFYHLHALDWVDVMSALKADPKRTSELQQLVSPAHPLSSAGY
FRDIQNRLKRFVESGQLGPFMNGYWGSKAYVLPPEANLMAVTHYLEALDLQKEWVKIHTIFGGKNPHPNYLVGGVPCAIN
LDGASAPVNMERLSFVKARIDEIIEFNKNVYVPDVLAIGTLYKQAGWLYGGGLAATNVLDYGEYPNVAYNKSTDQLPGGA
ILNGNWDEVFPVDPRDSQQVQEFVSHSWYKYADESVGLHPWDGVTEPNYVLGANTKGTRTRIEQIDESAKYSWIKSPRWR
GHAMEVGPLSRYILAYAHARSGNKYAERPKEQLEYSAQMINSAIPKALGLPETQYTLKQLLPSTIGRTLARALESQYCGE
MMHSDWHDLVANIRAGDTATANVDKWDPATWPLQAKGVGTVAAPRGALGHWIRIKDGRIENYQCVVPTTWNGSPRDYKGQ
IGAFEASLMNTPMVNPEQPVEILRTLHSFDPCLACSTH

The query sequence (length=598) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4iub:L 602 601 1.0000 0.9934 0.9950 0.0 5d51:L, 4iuc:L, 4iud:L, 5mdj:L, 5mdk:L, 5mdl:L, 7odg:L, 7odh:L, 8pou:L, 8pov:L, 8pow:L, 8pox:L, 8poz:L, 3rgw:L, 4ttt:L
2 3ayx:A 595 596 0.7241 0.7277 0.7265 0.0 3ayx:C, 3ayz:A, 3ayz:C, 5y34:A, 5y34:C
3 4c3o:A 583 603 0.6538 0.6707 0.6484 0.0 4c3o:C, 4c3o:E
4 5a4f:L 581 601 0.5786 0.5955 0.5757 0.0 5a4f:M, 5a4i:L, 5a4i:M, 5a4m:L, 5a4m:M, 5adu:L, 5adu:M, 6fpi:L, 6fpi:M, 6fpo:L, 6fpo:M, 6fpw:L, 6fpw:M, 6g7r:L, 6g7r:M, 6g94:L, 6g94:M, 6g94:J, 6g94:K, 6gal:L, 6gal:M, 4gd3:L, 4gd3:M, 4gd3:J, 4gd3:K, 5jrd:L, 5jrd:M, 5lmm:L, 5lmm:M, 5lry:L, 5lry:M, 6rp2:L, 6rp2:M, 4ue3:LLL, 4ue3:MMM, 3uqy:L, 3uqy:M, 3usc:L, 3usc:M, 3use:L, 3use:M
5 3myr:D 561 587 0.5234 0.5579 0.5332 0.0 3myr:B, 3myr:F, 3myr:H
6 6ehq:L 551 590 0.4264 0.4628 0.4322 7.33e-155 6ehq:M, 6ehs:L, 6ehs:M, 6en9:L, 6en9:M, 6g7m:L, 6g7m:M, 6gam:L, 6gam:M, 6gan:L, 6gan:M, 7nem:L, 7nem:M, 6syo:LLL, 6syo:MMM, 6syx:LLL, 6syx:MMM, 6szd:LLL, 6szd:MMM, 6szk:LLL, 6szk:MMM, 7vxq:A, 7vxq:C, 5xvb:L, 5xvb:M, 5xvc:L, 5xvc:M, 5xvd:L, 5xvd:M
7 1h2a:L 534 587 0.4181 0.4682 0.4259 4.36e-153 1h2r:L, 4u9h:L, 4u9i:L, 1ubh:L, 1ubj:L, 1ubk:L, 1ubl:L, 1ubm:L, 1ubo:L, 1ubr:L, 1ubt:L, 1ubu:L, 8w6x:L, 1wuh:L, 1wui:L, 1wuj:L, 1wuk:L, 1wul:L, 5xle:L, 5xlf:L, 5xlg:L, 5xlh:L, 5y4n:L
8 3cur:H 545 591 0.4214 0.4624 0.4264 1.20e-149 3cur:I, 3cur:J, 3cus:Q, 3cus:R, 3cus:S, 1frf:L, 3h3x:Q, 3h3x:R, 3h3x:S, 4ucq:Q, 4ucq:R, 4ucq:S, 4ucw:Q, 4ucw:R, 4ucw:S, 4ucx:Q, 4ucx:R, 4ucx:S, 4ud2:S, 4ud2:Q, 4ud2:R, 4ud6:Q, 4ud6:R, 4ud6:S, 4ue2:Q, 4ue2:R, 4ue2:S, 4ue6:R, 4ue6:Q, 4ue6:S, 4ueq:Q, 4ueq:R, 4ueq:S, 4ueq:T, 4ueq:U, 4ueq:V, 4uew:Q, 4uew:R, 4uew:S, 4upe:Q, 4upe:R, 4upe:S, 4upv:Q, 4upv:R, 4uql:Q, 4uql:R, 4uqp:Q, 4uqp:R, 4urh:Q, 4urh:S, 4urh:R, 1yqw:Q, 1yqw:R, 1yqw:S, 1yrq:H, 1yrq:I, 1yrq:J, 1yrq:K, 1yrq:M, 1yrq:N
9 1frv:B 530 588 0.4013 0.4528 0.4082 1.01e-141 1frv:D, 2frv:L, 2frv:B, 2frv:D, 2frv:F, 2frv:H, 2frv:J, 1yq9:H, 1yq9:I
10 1e3d:B 537 595 0.4164 0.4637 0.4185 4.14e-140 1e3d:D
11 6rtp:B 484 583 0.3110 0.3843 0.3190 1.77e-78 5jsh:B, 5jsk:B, 5jsu:B, 5jsy:B, 5jt1:B, 6ru9:B, 6ruc:B, 2wpn:B, 6z7r:B, 6z7r:D, 6z8j:B, 6z8j:D, 6z8m:B, 6z8o:B, 6z8o:D, 6z9g:B, 6z9g:D, 6z9g:F, 6z9g:H, 6z9o:B, 6za1:B, 3ze6:B, 3ze7:B, 3ze8:B, 3ze9:B, 3zea:B
12 4kl8:L 489 585 0.2993 0.3661 0.3060 1.17e-73 1cc1:L, 4kl8:M, 4kn9:L, 4kn9:M, 4ko1:L, 4ko1:M, 4ko2:L, 4ko2:M, 4ko3:L, 4ko3:M, 4ko4:L, 4ko4:M
13 8dqv:A 513 618 0.2709 0.3158 0.2621 4.52e-44 8dqv:C, 7utd:A, 7utd:C, 7utd:E, 7utd:G, 7utd:I, 7utd:K, 7utd:M, 7utd:O, 7uur:C, 7uur:F, 7uus:A, 7uus:C, 7uus:E, 7uus:G, 7uus:I, 7uus:K, 7uus:M, 7uus:O
14 5aa5:G 561 617 0.2609 0.2781 0.2528 2.93e-37 5aa5:C, 5aa5:E, 5aa5:K, 5aa5:I, 5aa5:L
15 5odc:F 447 115 0.0769 0.1029 0.4000 1.68e-20 5odc:L, 5odh:F, 5odh:L, 5odi:F, 5odi:L, 5odq:F, 5odq:L, 5odr:F, 5odr:L
16 5odc:F 447 83 0.0468 0.0626 0.3373 2.86e-04 5odc:L, 5odh:F, 5odh:L, 5odi:F, 5odi:L, 5odq:F, 5odq:L, 5odr:F, 5odr:L
17 7t2r:D 447 113 0.0736 0.0984 0.3894 1.24e-18 7t2r:I, 7t30:D, 7t30:I
18 7t2r:D 447 141 0.0619 0.0828 0.2624 0.003 7t2r:I, 7t30:D, 7t30:I
19 4ci0:A 385 116 0.0786 0.1221 0.4052 1.58e-18 4omf:A
20 4ci0:A 385 89 0.0452 0.0701 0.3034 4.65e-06 4omf:A
21 5xf9:D 455 129 0.0652 0.0857 0.3023 4.92e-14 5xf9:H, 5xfa:D, 5xfa:H
22 5xf9:D 455 137 0.0635 0.0835 0.2774 1.98e-06 5xf9:H, 5xfa:D, 5xfa:H
23 6qgr:A 437 105 0.0552 0.0755 0.3143 1.89e-11 6qgt:A, 6qii:A
24 6qgr:A 437 248 0.0987 0.1350 0.2379 2.23e-07 6qgt:A, 6qii:A
25 7z0s:E 532 96 0.0502 0.0564 0.3125 5.33e-09 7z0t:E
26 6cfw:L 374 146 0.0619 0.0989 0.2534 8.19e-08
27 6cfw:L 374 82 0.0368 0.0588 0.2683 0.18
28 7zmb:C 441 102 0.0401 0.0544 0.2353 0.009 7zm7:C, 7zmg:C
29 3e5z:A 290 76 0.0435 0.0897 0.3421 0.017 3e5z:B
30 6i0d:4 384 93 0.0385 0.0599 0.2473 0.17 6i0d:E, 6i1p:E, 3i9v:4, 3iam:4, 3ias:4, 3ias:D, 3ias:M, 3ias:V, 3m9s:4, 3m9s:D, 6q8o:4, 6q8o:E, 6q8w:4, 6q8w:E, 6q8x:4, 6q8x:E, 2ybb:4
31 6ct6:B 331 117 0.0502 0.0906 0.2564 0.40 6ct6:A
32 4hvl:A 369 31 0.0251 0.0407 0.4839 1.4
33 6l8n:A 810 36 0.0234 0.0173 0.3889 1.4
34 8xaw:B 567 71 0.0385 0.0406 0.3239 1.8 8xaw:C, 8xaw:D, 8xaw:E, 8xaw:A, 8xaw:F, 8xax:A, 8xax:B, 8xax:C, 8xax:D, 8xax:E, 8xax:F, 8xay:B, 8xay:C, 8xay:D, 8xay:E, 8xay:A, 8xay:F
35 8qby:D 410 91 0.0368 0.0537 0.2418 2.0
36 6ovi:A 210 71 0.0351 0.1000 0.2958 2.3 6ovi:B, 6ovi:C
37 8ebw:H 532 172 0.0719 0.0808 0.2500 4.1 8ebs:H, 8ebt:H, 8ebv:H, 8ebx:H
38 7mp4:A 534 49 0.0301 0.0337 0.3673 4.3 7mp4:B, 7mp4:C, 7mp4:D, 7mp4:E, 7mp4:F, 7mp4:G, 7mp4:H
39 5nem:2 214 80 0.0401 0.1121 0.3000 5.9
40 1t47:A 362 106 0.0435 0.0718 0.2453 6.3 1t47:B
41 5hab:B 463 41 0.0284 0.0367 0.4146 7.1 5haa:A, 5haa:B, 5hab:A, 6llb:A, 6llb:B, 5ws2:A, 5ws2:B
42 6o8w:E 206 107 0.0502 0.1456 0.2804 9.6 7nhk:I, 6o8x:E, 6o8y:E, 6o8z:E, 6o90:E, 7p7q:I, 7p7r:I, 7p7s:I, 7p7t:I, 7p7u:I, 6w6p:E, 6wu9:E
43 7mdi:A 734 125 0.0502 0.0409 0.2400 9.9 7mdi:B, 7mdi:D, 7mdi:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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